Catabolic Plasmids - UQ eSpace
... cAMP-independent systems of Bacillus, acting in opposition to specific, plasmid-borne positive regulation. This is based generally on a two-component sensor/regulator ...
... cAMP-independent systems of Bacillus, acting in opposition to specific, plasmid-borne positive regulation. This is based generally on a two-component sensor/regulator ...
Applications of RNA minimum free energy computations
... sequences, which are processed from a stem-loop precursor by Dicer (Tuschl, 2003; Lim et al., 2003) – see Figure 1, which depicts the predicted secondary structure for C. elegans let-7 precursor RNA. MicroRNA is (approximately) the reverse complement of a portion of transcribed mRNA and has been sho ...
... sequences, which are processed from a stem-loop precursor by Dicer (Tuschl, 2003; Lim et al., 2003) – see Figure 1, which depicts the predicted secondary structure for C. elegans let-7 precursor RNA. MicroRNA is (approximately) the reverse complement of a portion of transcribed mRNA and has been sho ...
Identification and Functional Analysis of Mutations in the Hepatocyte
... mutation (Pro379fsdelCT) in exon 6, and another patient carried a novel 2-bp substitution at nucleotides 145 (G to A) and 146 (C to A) from the transcriptional site of the promoter region. These mutations were identified in heterozygous form and were not identified in 64 unrelated healthy control su ...
... mutation (Pro379fsdelCT) in exon 6, and another patient carried a novel 2-bp substitution at nucleotides 145 (G to A) and 146 (C to A) from the transcriptional site of the promoter region. These mutations were identified in heterozygous form and were not identified in 64 unrelated healthy control su ...
The tightly regulated promoter of the xanA gene of
... 1990). This mutation results in overexpression of some genes such as amdS and nil expression of others such as uapA (Arst and Scazzocchio, 1975; Hynes, 1975; Gorfinkiel et al., 1993; Diallinas et al., 1995; Ravagnani et al., 1997) and still virtually unchanged expression of others such as azgA (Cecc ...
... 1990). This mutation results in overexpression of some genes such as amdS and nil expression of others such as uapA (Arst and Scazzocchio, 1975; Hynes, 1975; Gorfinkiel et al., 1993; Diallinas et al., 1995; Ravagnani et al., 1997) and still virtually unchanged expression of others such as azgA (Cecc ...
Structure, expression and chromosomal location of the Oct
... group of related transcription factors containing a bipartite DNA-binding domain of 81 and 60 conserved amino acids which are separated by a poorly conserved linker sequence (reviewed in Sch61er, 1991). With the exception of these two regions, the proteins of this family are highly divergent. The PO ...
... group of related transcription factors containing a bipartite DNA-binding domain of 81 and 60 conserved amino acids which are separated by a poorly conserved linker sequence (reviewed in Sch61er, 1991). With the exception of these two regions, the proteins of this family are highly divergent. The PO ...
guidelines for usage of the vetgen dna marker
... range of causative factors identified. A specific progressive renal disease of young dogs has been reported on for the following breeds: Bedlington Terrier, Bull Terrier (miniature), Cocker Spaniel, Doberman Pincher, Keeshond, Lhasa Apso, Malamute, Norwegian Elkhound, Samoyed, Shih Tzu, Soft Coated ...
... range of causative factors identified. A specific progressive renal disease of young dogs has been reported on for the following breeds: Bedlington Terrier, Bull Terrier (miniature), Cocker Spaniel, Doberman Pincher, Keeshond, Lhasa Apso, Malamute, Norwegian Elkhound, Samoyed, Shih Tzu, Soft Coated ...
Non-Mendelian Inheritance
... assumed to occur as a result of methylation. Studies using CsCl density gradient, highpressure liquid chromatography, and restriction endonucleases have shown that mt+ cpDNAs are methylated but mt- cpDNA are not. Furthermore, the isolation of DNA methyltansferases from C.reinhardtii with molecular w ...
... assumed to occur as a result of methylation. Studies using CsCl density gradient, highpressure liquid chromatography, and restriction endonucleases have shown that mt+ cpDNAs are methylated but mt- cpDNA are not. Furthermore, the isolation of DNA methyltansferases from C.reinhardtii with molecular w ...
Archives of Microbiology
... nor whether the unique addition of 21 nucleotides in the vnfDG fusion area of Anabaena sp. CH1 is of functional signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to those from Methanosarcina spp. and were clearly separated f ...
... nor whether the unique addition of 21 nucleotides in the vnfDG fusion area of Anabaena sp. CH1 is of functional signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to those from Methanosarcina spp. and were clearly separated f ...
Newton E. Morton - The American Society of Human Genetics
... to Rh was identified 25 years later as protein band 4.1. Subsequently several dominant alleles at different loci unlinked to each other were identified, including spectrin (SPTA1) and spectrin (SPTB), initially coded EL1, EL2, EL3. A similar code was later applied to other diseases of high penet ...
... to Rh was identified 25 years later as protein band 4.1. Subsequently several dominant alleles at different loci unlinked to each other were identified, including spectrin (SPTA1) and spectrin (SPTB), initially coded EL1, EL2, EL3. A similar code was later applied to other diseases of high penet ...
Direct Sequence Analysis of the 14q+ and 18q
... translocation in these tumors. The breakpoint on bcl-2 fell within the range of previously determined7 breaks in the mbr region. There was a clear preponderance (5 of 7) for the J, member of the J, family. Most of the J, sequences had some single base differences when compared with their germline eq ...
... translocation in these tumors. The breakpoint on bcl-2 fell within the range of previously determined7 breaks in the mbr region. There was a clear preponderance (5 of 7) for the J, member of the J, family. Most of the J, sequences had some single base differences when compared with their germline eq ...
Brassinosteroid-6-Oxidases from Arabidopsis and
... acid residues and conserved ones are indicated by hatched characters. Gaps introduced to improve the alignment are shown by hyphens. The GenBank/EMBL/DDBJ accession nos. of the AtBR6ox gene (CYP85) and the tomato Dwarf gene (CYP85) are AB035868 and U54770, respectively. The heme-binding signature se ...
... acid residues and conserved ones are indicated by hatched characters. Gaps introduced to improve the alignment are shown by hyphens. The GenBank/EMBL/DDBJ accession nos. of the AtBR6ox gene (CYP85) and the tomato Dwarf gene (CYP85) are AB035868 and U54770, respectively. The heme-binding signature se ...
Genetics and ecosystems - Pearson Schools and FE Colleges
... As temperature increases the rate of chemical reactions increases. This increases the release of heat from these reactions. As a result the animal gets even warmer. This speeds up the chemical reactions even more. Causes heat stroke, enzymes may be denatured and the animal dies. ...
... As temperature increases the rate of chemical reactions increases. This increases the release of heat from these reactions. As a result the animal gets even warmer. This speeds up the chemical reactions even more. Causes heat stroke, enzymes may be denatured and the animal dies. ...
Fifteen years of genomewide scans for selection: trends, lessons
... mutational events occurs span several orders of magnitude. In humans, single-nucleotide mutations happen at a rate of 10 8–10 9/site/generation (Nachman & Crowell 2000; Roach et al. 2010), microsatellite mutation rates range from 10 2 to 10 6 (Weber & Wong 1993; Sun et al. 2012), and large-scale cop ...
... mutational events occurs span several orders of magnitude. In humans, single-nucleotide mutations happen at a rate of 10 8–10 9/site/generation (Nachman & Crowell 2000; Roach et al. 2010), microsatellite mutation rates range from 10 2 to 10 6 (Weber & Wong 1993; Sun et al. 2012), and large-scale cop ...
The ISME Journal
... be very densely colonized by these organisms (Figure 1) and it can be assumed that many microbes are associated with epiphytes rather than with the host plant. Bacterial communities on leaves are limited by nutrient availability and it is known that mainly simple sugars, which leach from the interio ...
... be very densely colonized by these organisms (Figure 1) and it can be assumed that many microbes are associated with epiphytes rather than with the host plant. Bacterial communities on leaves are limited by nutrient availability and it is known that mainly simple sugars, which leach from the interio ...
Frequent, independent transfers of a catabolic gene from bacteria to
... horizontal gene transfer (HGT). Prokaryotes adapt largely by HGT, and strains of a particular species can differ by large fractions of their genome [2–6]. Long thought to be a prokaryote specialty, HGT is now recognized as a mechanism of genetic innovation in eukaryotes as well [7–10]. Genome analys ...
... horizontal gene transfer (HGT). Prokaryotes adapt largely by HGT, and strains of a particular species can differ by large fractions of their genome [2–6]. Long thought to be a prokaryote specialty, HGT is now recognized as a mechanism of genetic innovation in eukaryotes as well [7–10]. Genome analys ...
Selective regain of egfr gene copies in CD44+/CD24
... © 2010 Agelopoulos et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the origi ...
... © 2010 Agelopoulos et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the origi ...
Defining the Epigenetic Mechanism of Asymmetric Cell Division of
... 1987; Klar 1990). This rule results from asymmetric cell division occurring in each of the two consecutive generations. Such a growth pattern is analogous to the mammalian stem cell asymmetric cell division, in which one daughter cell behaves like the parental cell, while the other daughter cell di ...
... 1987; Klar 1990). This rule results from asymmetric cell division occurring in each of the two consecutive generations. Such a growth pattern is analogous to the mammalian stem cell asymmetric cell division, in which one daughter cell behaves like the parental cell, while the other daughter cell di ...
- ResearchOnline@JCU
... 2350 within exon 2 (g.54014C4T). The residue is highly conserved in mammals and birds (Figure 1d), and is located within a wellconserved region that encodes the extracellular protein domain. As a result of this premature stop codon, mutant mRNA is predicted to undergo nonsense mediated decay. RNF43 ...
... 2350 within exon 2 (g.54014C4T). The residue is highly conserved in mammals and birds (Figure 1d), and is located within a wellconserved region that encodes the extracellular protein domain. As a result of this premature stop codon, mutant mRNA is predicted to undergo nonsense mediated decay. RNF43 ...
DNA extraction from frozen fieldcollected and dehydrated herbarium
... of many Basidiomycetes species are coriaceous or even woody hard, which poses additional difficulties in DNA extraction. In the studied species, all these problems occur: Hymenochaetaceae are characterized by the extensive production of styrylpyrones and complex phenolic compounds in their basidioma ...
... of many Basidiomycetes species are coriaceous or even woody hard, which poses additional difficulties in DNA extraction. In the studied species, all these problems occur: Hymenochaetaceae are characterized by the extensive production of styrylpyrones and complex phenolic compounds in their basidioma ...
Genetics- Ch. 5 text notes
... • Is the likelihood that particular crossover frequency data indicates linkage • LOD scores of 3 or greater are considered significant and indicate the data would be observed by chance 1/1000 times • Was used when disease genes were not identified ...
... • Is the likelihood that particular crossover frequency data indicates linkage • LOD scores of 3 or greater are considered significant and indicate the data would be observed by chance 1/1000 times • Was used when disease genes were not identified ...
software development and application in bioinformatics: single
... over another? It is also an important step toward implementing more accurate and more efficient algorithms for SNPs detection. This work can also be used toward improving an already existing application. I present some of the most commonly used applications for SNP discovery as well as how and when ...
... over another? It is also an important step toward implementing more accurate and more efficient algorithms for SNPs detection. This work can also be used toward improving an already existing application. I present some of the most commonly used applications for SNP discovery as well as how and when ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse