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1 X chromosome crossover formation and genome stability in
1 X chromosome crossover formation and genome stability in

... (COUTEAU AND ZETKA 2011). These phenotypes of H2AK5ac are regulated, at least in part, by the histone acetyltransferase (HAT) mys-1, the worm homolog of Tip60, the catalytic subunit of the NuA4 HAT complex. Tip60 complexes are known to modulate the DDR through acetylation of the conserved sensor, AT ...
slides - Referent Tracking Unit
slides - Referent Tracking Unit

Ch. 7: Presentation Slides
Ch. 7: Presentation Slides

... • When chromosome 21 is one of the acrocentrics in a Robertsonian translocation, the rearrangement leads to a familial type of Down syndrome • The heterozygous carrier is phenotypically normal, but a high risk of Down syndrome results from aberrant segregation in meiosis • Approximately 3 percent of ...
slides - Referent Tracking Unit
slides - Referent Tracking Unit

... genes do?’ is sensible, one may ask … – What does the word ‘gene’ then mean? •  terminological question ...
Congenital adrenal hyperplasia (CAH)
Congenital adrenal hyperplasia (CAH)

... hormones within the body. Hormones are chemical messengers that switch on and off processes within the body. The adrenal glands consist of two parts: „„the medulla (inner section) which makes the hormone ‘adrenaline’ which is part of the ‘fight or flight’ response a person has when stressed. This is ...
Topic 7: The Axial Skeleton Divisions of the Skeleton:
Topic 7: The Axial Skeleton Divisions of the Skeleton:

... Rib cage is external to the ________________ Costal scerotomal cells move laterally, not ventrally ...
poéticas del desierto: dos voces
poéticas del desierto: dos voces

... expressions give us clues on the behavior of our conceptual system, which linguistically reflects conceptual metaphors (Oliveira, 2009). According to Steen (1997) ‘[…] cognitive linguistics are going out of their way to show that linguistic metaphor is fundamentally conceptual, but that in doing so, ...
Archives of Microbiology 167:
Archives of Microbiology 167:

... heterocyst glycolipids. Sequence analysis around the site of insertion revealed an ORF of 3,159 base pairs, termed hglE. hglE putatively encodes a 115.4-kDa protein containing two domains with conserved amino acid sequences identified with acyl transferase and the chain length factor variation of β- ...
Concordance trees, concordance factors, and the exploration of
Concordance trees, concordance factors, and the exploration of

... great progress is being made (e.g., Rosenberg, 2002; Liu & Pearl, 2006), it is not yet practical to reliably infer a population tree from molecular data, especially in cases that involve reticulation at the population level (e.g., introgression, lateral gene transfer). Instead of estimating a popula ...
Molecular Dynamics of a Presynaptic Active Zone
Molecular Dynamics of a Presynaptic Active Zone

... analyses usually involve protein expression methods that override endogenous regulatory mechanisms, and therefore cause overexpression and temporal or spatial misexpression of exogenous fusion proteins, which may seriously compromise the physiological validity of such experiments. These problems can ...
THE EFFECT OF INBREEDING ON THE VARIATION DUE TO
THE EFFECT OF INBREEDING ON THE VARIATION DUE TO

Impact of nucleosome dynamics and histone modifications
Impact of nucleosome dynamics and histone modifications

... Histone modification is one of the first steps of the gene expression control cascade by facilitating the recruitment of transcription factors and/or other proteins to chromatin. Among them, acetylation and methylation of various lysine residues in histones H3 and H4 are the most studied in relation ...
Elongation and Termination of Transcription
Elongation and Termination of Transcription

... • HIV LTR is also regulated at initiation by a large number of transcription factors that bind upstream of the core promoter, all within the LTR. ...
Full-Text PDF
Full-Text PDF

... fully answered. Expression analysis of pollen allergens does not yet have any specific protocols or methods developed, despite a very good sequence background available in public bioinformatics databases. However, research in this area of interest has a great application potential for breeding and b ...
Non-conflict theories for the evolution of genomic imprinting
Non-conflict theories for the evolution of genomic imprinting

... and different stages of development, and even among individuals. Moreover, although the direction of imprinting at a particular locus (that is, whether the maternal or paternal copy’s expression is downregulated) is consistent within a species, there is significant discordance among species, with th ...
Expression analysis of Arc in mouse brain Theresa Köhler
Expression analysis of Arc in mouse brain Theresa Köhler

... memory. Arc is induced in various situations of neuronal activity. In previous experiments it was found differentially expressed in female virgin mice exposed to pups compared to mice without exposure. This lead to the conclusion that maternal behavior might be an inductor for Arc expression. To sup ...
post-transcription
post-transcription

... • One benefit of genes with introns is a phenomenon called alternative splicing • A pre-mRNA with multiple introns can be spliced in different ways – This will generate mature mRNAs with different combinations of exons ...
Synergistic interaction of the two paralogous
Synergistic interaction of the two paralogous

... functional analysis of Arabidopsis LRX1 has shown that it is involved in cell morphogenesis of root hairs. In this work, we have studied LRX2, a paralog of LRX1. LRX2 expression is mainly found in roots and is responsive to factors promoting or repressing root hair formation. The function of LRX1 an ...
A Genome-Wide Survey of the NAC Transcription
A Genome-Wide Survey of the NAC Transcription

... al. (2010) reported 151 and 117 NAC genes in rice and Arabidopsis, respectively. To date, a few of these genes have been characterized but most of the NAC family members have yet to be studied, despite the likelihood that these genes play important roles in the physiology of plants. Substantial expe ...
controlling flowering time and plant height in
controlling flowering time and plant height in

... et a!. (1993). However, in many cases the traits vary quantitatively suggesting that they are controlled by many genes. Molecular marker maps, usually based on RFLPs, have been widely used to map quantitative trait loci ...
Genetics of Male Infertility - the Infertility Center of St. Louis
Genetics of Male Infertility - the Infertility Center of St. Louis

... and elsewhere, but the repetitive nucleotide sequences which characterize much of the Y chromosome made it very difficult with standard STS markers to define smaller deletions (104). The unusually repetitive sequence structure of the AZFc region of the Y plagued even the first attempts at constructi ...
MARKER GENE TRANSFER TO WINTER DURUM WHEAT (Triticum
MARKER GENE TRANSFER TO WINTER DURUM WHEAT (Triticum

... Mature embryos of durum wheat were found to be suitable explant material for transformation studies. For the tested gold particles, 1.6 µm average diameter was found to give better results if used at 650 psi bombardment pressure and at 6 cm target distance. However 1.0 µm average diameter gold parti ...
Mitochondrial genes in the colourless alga Prototheca wickerhamii
Mitochondrial genes in the colourless alga Prototheca wickerhamii

... Prototheca wickerhamii contains two mosaic genes as was revealed from complete sequencing of the circular extranuclear genome. The genes for the large subunlt of the ribosomal RNA (LSUrRNA) as well as for subunlt I of the cytochrome oxidase (coxl) carry two and three Intronic sequences respectively. ...
PDF
PDF

... that wg is required for specification of ventral structures, and that loss of wg activity can result in supernumerary limbs that result from bifurcations along the P/D axis (Baker, 1988; Peifer et al., 1990; Couso et al., 1993). Ectopic expression of wg in clones has provided additional insight into ...
Alnylam Licenses Intellectual Property from Cold Spring Harbor
Alnylam Licenses Intellectual Property from Cold Spring Harbor

... major breakthrough, and the journal Science named RNAi the top scientific achievement of 2002 as well as one of the top ten scientific advances of 2003. Because many diseases are caused by the inappropriate activity of specific genes, the ability to silence such genes selectively through RNAi could ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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