Inferring Host Gene Subnetworks Involved in Viral
... Systematic, genome-wide loss-of-function experiments can be used to identify host factors that directly or indirectly facilitate or inhibit the replication of a virus in a host cell. We present an approach that combines an integer linear program and a diffusion kernel method to infer the pathways th ...
... Systematic, genome-wide loss-of-function experiments can be used to identify host factors that directly or indirectly facilitate or inhibit the replication of a virus in a host cell. We present an approach that combines an integer linear program and a diffusion kernel method to infer the pathways th ...
Role of 1-aminocyclopropane-1-carboxylate (ACC) Synthases
... in flower petal senescence is important and is cultivar dependent with variable cultivar sensitivity. 2) They point to the need for additional work, because results in some instances are contradictory. While it makes sense in the studies with the miniature potted roses of short- and long-lived flowe ...
... in flower petal senescence is important and is cultivar dependent with variable cultivar sensitivity. 2) They point to the need for additional work, because results in some instances are contradictory. While it makes sense in the studies with the miniature potted roses of short- and long-lived flowe ...
Bombay Phenotype or O h
... Oh (hh) individuals are all non-secretors of ABH substances, because both the H gene and the Se gene must be inherited for the ABH antigens to be found in secretions. ...
... Oh (hh) individuals are all non-secretors of ABH substances, because both the H gene and the Se gene must be inherited for the ABH antigens to be found in secretions. ...
Transcriptional Repression of the
... The luciferase gene driven by different promoter constructs was assayed for responsiveness to cotransfected AR. The promoter constructs studied are 21500 to 145 bp of the human a-subunit gene with an intact ARE (21500 wt), 21500 to 145 bp of the human a-subunit gene with a block replacement mutation ...
... The luciferase gene driven by different promoter constructs was assayed for responsiveness to cotransfected AR. The promoter constructs studied are 21500 to 145 bp of the human a-subunit gene with an intact ARE (21500 wt), 21500 to 145 bp of the human a-subunit gene with a block replacement mutation ...
C.W. Cunningham 2004
... datasets were manually aligned. As many of the ITS sequences were identical within an individual, the number of taxa in the ITS dataset was reduced by only considering the two most divergent alleles within each individual. Tests of Selection Mussel F- and M-mtDNA are known to be under different sele ...
... datasets were manually aligned. As many of the ITS sequences were identical within an individual, the number of taxa in the ITS dataset was reduced by only considering the two most divergent alleles within each individual. Tests of Selection Mussel F- and M-mtDNA are known to be under different sele ...
The role of mutagenesis in defining genes in behaviour
... ability to define quantitative outliers by statistical means. Some tests appear to introduce a high variability and may be influenced by human interference.13 Problems may also be related to the number of successive tests mice are subjected to in order to increase test information density.14,15 As a ...
... ability to define quantitative outliers by statistical means. Some tests appear to introduce a high variability and may be influenced by human interference.13 Problems may also be related to the number of successive tests mice are subjected to in order to increase test information density.14,15 As a ...
Cover Letter
... by the glimmer and gene mark. Gap -1 is more compact than Gap 20. Thus the LORF is selected. CDS 24352 - 24798 /note=It is worth noticing that the gap is 94, bigger than the 30 limit. CDS 24795 - 25142 /note=Start at 24795 has better score and longer ORF than 24810 (called by Glimmer and GeneMark) C ...
... by the glimmer and gene mark. Gap -1 is more compact than Gap 20. Thus the LORF is selected. CDS 24352 - 24798 /note=It is worth noticing that the gap is 94, bigger than the 30 limit. CDS 24795 - 25142 /note=Start at 24795 has better score and longer ORF than 24810 (called by Glimmer and GeneMark) C ...
Biotechnology and Biosafety Awareness Namibia
... simply hearing about something vs. understanding it ...
... simply hearing about something vs. understanding it ...
ENVIRONMENTAL SPREAD OF ANTIBIOTIC MOLECULES
... Kozak et al., 2009). Even in the surrounding air of pig farms, Enterococcus spp., Staphylococcus spp. and Streptococcus spp. carrying genes that confer resistance to tetracyclines, macrolides, lincosamides and streptogramins were observed (Sapkota et al., 2006), suggesting that air might also act as ...
... Kozak et al., 2009). Even in the surrounding air of pig farms, Enterococcus spp., Staphylococcus spp. and Streptococcus spp. carrying genes that confer resistance to tetracyclines, macrolides, lincosamides and streptogramins were observed (Sapkota et al., 2006), suggesting that air might also act as ...
video slide
... – This cDNA represents only part of the genome – This is advantageous for; • Studying the genes responsible for specialized functions of a particular type of cells such as brain or liver cells. • In addition by making cDNA library from cells of same type at different stages of life of an organism, r ...
... – This cDNA represents only part of the genome – This is advantageous for; • Studying the genes responsible for specialized functions of a particular type of cells such as brain or liver cells. • In addition by making cDNA library from cells of same type at different stages of life of an organism, r ...
Reciprocal Deletion and Duplication of 17p11.2-11.2
... and failure to thrive. In our cases, both of our patients showed developmental language delay and intellectual disability. Although patient 1 was too young to show full expression of clinical features, he showed mildly dysmorphic features including a broad, square-shaped forehead, brachycephaly, an ...
... and failure to thrive. In our cases, both of our patients showed developmental language delay and intellectual disability. Although patient 1 was too young to show full expression of clinical features, he showed mildly dysmorphic features including a broad, square-shaped forehead, brachycephaly, an ...
Homeotic genes regulate the spatial expression
... transcription patterns of target or 'realizator' genes (Garcia-Bellido, 1977). In the epidermis, the nervous system, and the visceral mesoderm, cross-regulatory interactions have been observed among the homeotic genes; thus the first target genes to have been identified are homeotic genes (Hafen et ...
... transcription patterns of target or 'realizator' genes (Garcia-Bellido, 1977). In the epidermis, the nervous system, and the visceral mesoderm, cross-regulatory interactions have been observed among the homeotic genes; thus the first target genes to have been identified are homeotic genes (Hafen et ...
Frameshift mutations of RIZ, but no point mutations in RIZ1
... markers tested here is explainable by the small number of lesions investigated. In gastrointestinal and endometrial carcinomas, MSI has been an important other criterion in lesions with RIZ frameshift mutations (Piao et al., 2000; Chadwick et al., 2000). Therefore, there are two possible reasons for ...
... markers tested here is explainable by the small number of lesions investigated. In gastrointestinal and endometrial carcinomas, MSI has been an important other criterion in lesions with RIZ frameshift mutations (Piao et al., 2000; Chadwick et al., 2000). Therefore, there are two possible reasons for ...
the loci of evolution: how predictable is genetic
... product, either a protein or a mature RNA (Fig. 1). One can distinguish three main types of mutations: (1) coding changes, which alter the amino-acid sequence or the mature RNA nucleotide sequence; (2) cis-regulatory changes, which alter gene expression; and (3) genetic changes that alter both the c ...
... product, either a protein or a mature RNA (Fig. 1). One can distinguish three main types of mutations: (1) coding changes, which alter the amino-acid sequence or the mature RNA nucleotide sequence; (2) cis-regulatory changes, which alter gene expression; and (3) genetic changes that alter both the c ...
THE LOCI OF EVOLUTION: HOW PREDICTABLE IS GENETIC
... product, either a protein or a mature RNA (Fig. 1). One can distinguish three main types of mutations: (1) coding changes, which alter the amino-acid sequence or the mature RNA nucleotide sequence; (2) cis-regulatory changes, which alter gene expression; and (3) genetic changes that alter both the c ...
... product, either a protein or a mature RNA (Fig. 1). One can distinguish three main types of mutations: (1) coding changes, which alter the amino-acid sequence or the mature RNA nucleotide sequence; (2) cis-regulatory changes, which alter gene expression; and (3) genetic changes that alter both the c ...
Genetics Review
... • In purple people eaters, one-horn is dominant and no horns is recessive. • Draw a Punnet Square showing the cross of a purple people eater that is hybrid for horns, with a purple people eater that does not have horns. ...
... • In purple people eaters, one-horn is dominant and no horns is recessive. • Draw a Punnet Square showing the cross of a purple people eater that is hybrid for horns, with a purple people eater that does not have horns. ...
NanoString™: User Guide | nCounter® Expression Data Analysis
... Each miRGE CodeSet contains probes designed against sixteen ERCC transcript sequences. Six of these sequences are used as positive hybridization controls, two are used as ligation controls and eight are designed as negative controls. For each positive hybridization control, in-vitro transcribed RNA ...
... Each miRGE CodeSet contains probes designed against sixteen ERCC transcript sequences. Six of these sequences are used as positive hybridization controls, two are used as ligation controls and eight are designed as negative controls. For each positive hybridization control, in-vitro transcribed RNA ...
Analytical approaches to RNA profiling data for
... The mammalian brain is the most complex organ of the body, containing hundreds of intermingled cell populations. These cells can be classified into types according to their morphology, projections, functions and gene expression profiles. Currently, in vivo analysis of gene expression and translation ...
... The mammalian brain is the most complex organ of the body, containing hundreds of intermingled cell populations. These cells can be classified into types according to their morphology, projections, functions and gene expression profiles. Currently, in vivo analysis of gene expression and translation ...
Transcriptional analysis of the gene for glutamine synthetase II and
... especially important in nitrogen metabolism, as it is the only enzyme capable of ammonium assimilation under conditions of nitrogen starvation. So far, four dierent glutamine synthetase types (GSI, GSII, GSIII and GlnT) have been discovered in bacteria (for review, see Merrick and Edwards 1995). Al ...
... especially important in nitrogen metabolism, as it is the only enzyme capable of ammonium assimilation under conditions of nitrogen starvation. So far, four dierent glutamine synthetase types (GSI, GSII, GSIII and GlnT) have been discovered in bacteria (for review, see Merrick and Edwards 1995). Al ...
—1— User Guide © Copyright 2009 Robert C. Edgar, all rights
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
Extrapolation to the whole human genome
... and 22 for their prevalent functional classes and compared them to the classes for genes predicted using GenomeScan (Yeh et al., 2001). The total number of InterPro motif assignments and consequently GO-class assignments is much smaller for the nonprocessed pseudogenes in comparison with the gene to ...
... and 22 for their prevalent functional classes and compared them to the classes for genes predicted using GenomeScan (Yeh et al., 2001). The total number of InterPro motif assignments and consequently GO-class assignments is much smaller for the nonprocessed pseudogenes in comparison with the gene to ...
Protein expression pattern in cerebellum of Cav2.1 mutant, tottering
... We counted Purkinje cells in defined areas of cerebellum in a blinded manner. Four square counting frames (1 mm × 1 mm) were placed of the four regularly spaced sections. The number of Purkinje cells and granular cells in each counting frame and the average number was used for statistical analysis i ...
... We counted Purkinje cells in defined areas of cerebellum in a blinded manner. Four square counting frames (1 mm × 1 mm) were placed of the four regularly spaced sections. The number of Purkinje cells and granular cells in each counting frame and the average number was used for statistical analysis i ...
Julio`s MCB - Digital Access to Scholarship at Harvard
... the Mfrn genes, we utilized genome-wide chromatin immunoprecipitation (ChIP) datasets for the major erythroid transcription factor GATA-1. We identified the CRMs that faithfully drive the expression of Mfrn1 during blood and heart development and Mfrn2 ubiquitously. Through in vivo analyses of the M ...
... the Mfrn genes, we utilized genome-wide chromatin immunoprecipitation (ChIP) datasets for the major erythroid transcription factor GATA-1. We identified the CRMs that faithfully drive the expression of Mfrn1 during blood and heart development and Mfrn2 ubiquitously. Through in vivo analyses of the M ...
2006 - Genetics, development and evolution of adaptive
... ‘hood’ was selected to be small in some lines and large in others. Castle initially thought these size differences reflected different alleles of the major gene responsible for hooding; however, Wright showed that so-called modifier genes were responsible for variation in hood size, providing the fi ...
... ‘hood’ was selected to be small in some lines and large in others. Castle initially thought these size differences reflected different alleles of the major gene responsible for hooding; however, Wright showed that so-called modifier genes were responsible for variation in hood size, providing the fi ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.