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Divergent evolution of oxidosqualene cyclases in plants
Divergent evolution of oxidosqualene cyclases in plants

... OSC genes (Inagaki et al., 2011). One of these (Os02g04710 ⁄ OsOSC2) encodes cycloartenol synthase (CS), while a further two (Os11g08569 ⁄ OsOSC7 and Os11g18194 ⁄ OsOSC8) have been shown to synthesize the triterpenes, parkeol and achilleol B, respectively, in Saccharomyces cerevisiae GIL77 (Ito et a ...
Ribosome profiling reveals post-transcriptional buffering of divergent
Ribosome profiling reveals post-transcriptional buffering of divergent

... C. Joel McManus,1 Gemma E. May, Pieter Spealman, and Alan Shteyman Carnegie Mellon University, Department of Biological Sciences, Pittsburgh, Pennsylvania 15213, USA Understanding the patterns and causes of phenotypic divergence is a central goal in evolutionary biology. Much work has shown that mRN ...
Gene-environment correlation
Gene-environment correlation

... • Hidden G-C interaction may be one of the reasons why we rarely see C: The effects of the shared environment may be modified by genes • We should at least discuss this possibility • Still, our results are meaningful – given a certain environment ...
Punnet Squares, Linked Genes and Pedigrees
Punnet Squares, Linked Genes and Pedigrees

... Phenotype ratio: ...
Genes - Dallas ISD
Genes - Dallas ISD

... Location of Genes In sexually reproducing organisms, cells have a homologous pair of chromosomes (one from each parent). ...
Genetic Techniques for Biological Research Chapter8
Genetic Techniques for Biological Research Chapter8

Mendel Discovers “Genes” 9-1
Mendel Discovers “Genes” 9-1

... BOTH an A and a B allele has BOTH “A” and “B” glycoproteins on its ...
Heterologous products from the yeast Kluyveromyces lactis
Heterologous products from the yeast Kluyveromyces lactis

... Although a large amount of basic knowledge, molecular tools and protocols are available for model organisms, they may not fulfill all the requirements for a scalable process of heterologous protein production. This is particularly true for the production of biologically active eukaryotic proteins fr ...
Protein expression in plastids Peter B Heifetz* and Ann Marie Tuttle
Protein expression in plastids Peter B Heifetz* and Ann Marie Tuttle

... The plastid rpoA, rpoB, rpoC1 and rpoC2 genes encode the catalytic subunits of a eubacterial-type RNA polymerase that recognizes upstream sequences that have high homology to the consensus –10 and –35 regions typically found in eubacterial promoters. Promoter recognition by this plastid-encoded RNA ...
Chapter 17: From Gene to Protein 1. Overview of Gene Expression 2. Transcription
Chapter 17: From Gene to Protein 1. Overview of Gene Expression 2. Transcription

... How are Genes related to DNA? Genes are segments of DNA that code for a particular protein (or RNA molecule) • the human genome contains ~3 billion base pairs (bps) and ~25,000 genes • most genes encode proteins • when we talk about “genes” we will focus on those that express proteins ...
The genomic substrate for adaptive radiation in African cichlid fish
The genomic substrate for adaptive radiation in African cichlid fish

... reads or introns. These introns together with the set of transcribed exons were combined to produce a set of 40899 transcript models. The longest open reading frame in each of these models was BLAST-ed19 against the set of UniProt PE levels 1 and 2 protein sequences in order to classify the models a ...
Journal of Bacteriology
Journal of Bacteriology

... host-specific nod gene products, resulting in effective nodules on a limited range of host plants (1, 16, 38, 48). Other nod genes identified in R. leguminosarum bv. viciae are nodlJ, nodMNT (6, 54, 55), and nodO (11, 15). Mutations in these genes have more or less severe effects on nodulation, depe ...
Genetic Inheritance - leavingcertbiology.net
Genetic Inheritance - leavingcertbiology.net

... Gregor Mendel • Mendel developed separate populations of pea plants, each a pure breed (homozygous) for a particular quality – e.g. for height, Mendel developed purebred (homozygous) tall pea plants and purebred (homozygous) dwarf pea plants (this took a long time to achieve as Mendel had to check ...
Learning Objectives and Outcomes
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... This states that all species of all living things have evolved over time from common ancestors through the process of natural selection ...
Biology 3201
Biology 3201

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... The aim of a microarray experiment is to measure the gene expression levels of cDNA samples. We describe a Bayesian model based on the idea to interpret the microarray experiment as a selection procedure, where the mRNA molecules initially present in a tissue solution are stepwise selected, until ev ...
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Genetics Review - Biology Junction
Genetics Review - Biology Junction

... (many genes), they can not be traced to a single parent Many genes have been discovered through the study of genetic disorders - they can be dominant or recessive ...
pARA-R Restriction Digest: An Introduction to Plasmids and
pARA-R Restriction Digest: An Introduction to Plasmids and

... Cut DNA molecules from various organisms and recombine pieces ...
Integrons and the Origin of Antibiotic Resistance Gene Cassettes
Integrons and the Origin of Antibiotic Resistance Gene Cassettes

... vancomycin resistance gene cluster found in enterococci and those of the glycopeptide-producing actinomycetes. While no other direct evidence is presently available, many antibioticproducing strains other than those used industrially exist in nature and could be a source of resistance genes. The rec ...
Gene Regulation in Development and Evolution
Gene Regulation in Development and Evolution

... typical animal genome contains approximately 20,000 genes. This is not only true for comparatively simple creatures such as nematode worms, but also pertains to the “crown and summit” of animal evolution, the human genome. Differential gene expression can be defined as the synthesis of a protein (or ...
CAFE: Computational Analysis of gene Family Evolution
CAFE: Computational Analysis of gene Family Evolution

... mcl understands. Then we give the .abc file to mcxload, which creates a network and a dictionary file (.mci and .tab, respectively). These two files are then used by mcl to perform the clustering, which is done with the last two commands. The -I (inflation) parameter determines how granular the clus ...
C2005/F2401 `07 -- Lecture 15 -- Last Edited
C2005/F2401 `07 -- Lecture 15 -- Last Edited

... a. There is a different repressor protein for each operon. Repressor binds to specific sequence of DNA found in its respective operator. b. Synthesis of repressor protein is constitutive -- gene is always on. (State of repressor protein varies, not the amount; see below.) Question: Does the gene for ...
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H H

... Indep. asstmt. of chromos increases unique gene combos…8 million diff. combos of chromos in gametes!!! ...
genes. Numbers of 6-10 copies per genome have
genes. Numbers of 6-10 copies per genome have

... The SSU genes and flanking regions in TSSU3-2 and TSSU3-8 were sequenced. Using sequences of other SSU genes, the leader peptide, mature coding regions and introns were located. In Figure 2, the sequence of these two genes is shown and compared to that of a previously sequenced tobacco SSU gene, NtS ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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