Effect of microaerobiosis
... aerobic conditions following bubbling with air for 60 min. It is noteworthy to mention that the induction of microaerobic environment inside the culture itself is achieved by various methods including bubbling gases (such as N2, argon etc.) or by enzymatic reactions. In our study, we used real-time ...
... aerobic conditions following bubbling with air for 60 min. It is noteworthy to mention that the induction of microaerobic environment inside the culture itself is achieved by various methods including bubbling gases (such as N2, argon etc.) or by enzymatic reactions. In our study, we used real-time ...
To how many simultaneous hypothesis tests can normal, student's t or bootstrap calibration be applied?
... statistical problems, it is not uncommon to apply hypothesis tests in a highly simultaneous way. The number, ν say, of tests used can be much larger than the sample sizes, n, to which the tests are applied, yet we wish to calibrate the tests so that the overall level of the simultaneous test is accu ...
... statistical problems, it is not uncommon to apply hypothesis tests in a highly simultaneous way. The number, ν say, of tests used can be much larger than the sample sizes, n, to which the tests are applied, yet we wish to calibrate the tests so that the overall level of the simultaneous test is accu ...
Spider Syndrome - OSU Fact Sheets
... to the sex of the individual; these are called sex linked. Other genes, such as eye color, hair color, etc., are not related to an individual’s sex. These are called autosomal genes. An autosomal genetic trait can, therefore, be found in both the male and female. ...
... to the sex of the individual; these are called sex linked. Other genes, such as eye color, hair color, etc., are not related to an individual’s sex. These are called autosomal genes. An autosomal genetic trait can, therefore, be found in both the male and female. ...
A G Protein Alpha Subunit from Cochliobolus heterostrophus
... chromosome. Arrows show locations of primers (described in the text) used to generate 259- and 812-bp PCR products shown in C and the probe used in D. (B) Gene disruption vector pAG3.3 was constructed by ligating the 791-bp XhoI (indicated by X2)–PstI CGA1 fragment from pG2.1 and the 939-bp PstI–Xho ...
... chromosome. Arrows show locations of primers (described in the text) used to generate 259- and 812-bp PCR products shown in C and the probe used in D. (B) Gene disruption vector pAG3.3 was constructed by ligating the 791-bp XhoI (indicated by X2)–PstI CGA1 fragment from pG2.1 and the 939-bp PstI–Xho ...
What Do You Mean, “Epigenetic”?
... more advanced pursuits to determine how epigenetic processes occur. After all, how can scientists effectively study a process when they cannot even agree on how to define it? With the usage of the term epigenetic increasing exponentially across scientific and mainstream literature, one must wonder: fo ...
... more advanced pursuits to determine how epigenetic processes occur. After all, how can scientists effectively study a process when they cannot even agree on how to define it? With the usage of the term epigenetic increasing exponentially across scientific and mainstream literature, one must wonder: fo ...
Next Generation Sequencing Panel for Severe Congenital
... Partial exonic copy number changes and rearrangements of less than 400 bp may not be detected by array-CGH. Array-CGH will not detect low-level mosaicism, balanced translocations, inversions, or point mutations that may be responsible for the clinical phenotype. The sensitivity of this assay may be ...
... Partial exonic copy number changes and rearrangements of less than 400 bp may not be detected by array-CGH. Array-CGH will not detect low-level mosaicism, balanced translocations, inversions, or point mutations that may be responsible for the clinical phenotype. The sensitivity of this assay may be ...
Neutral and Non-Neutral Evolution of Duplicated Genes with Gene
... to maintain the process of gene conversion in duplicated genes in which higher dosage is favored. The human Y chromosome contains many genes that undergo frequent gene conversion [8]. These genes are expressed in the testis and are thought to be under strong selective pressure for higher dosage beca ...
... to maintain the process of gene conversion in duplicated genes in which higher dosage is favored. The human Y chromosome contains many genes that undergo frequent gene conversion [8]. These genes are expressed in the testis and are thought to be under strong selective pressure for higher dosage beca ...
RNA interference - genemol de Jean
... of 20-25 nucleotide-long RNA molecules that interfere with the expression of genes. They are naturally produced as part of the RNA interference (RNAi) pathway by the enzyme Dicer. They can also be exogenously (artificially) introduced by investigators to bring about th knockdown of a particular gene ...
... of 20-25 nucleotide-long RNA molecules that interfere with the expression of genes. They are naturally produced as part of the RNA interference (RNAi) pathway by the enzyme Dicer. They can also be exogenously (artificially) introduced by investigators to bring about th knockdown of a particular gene ...
The influence of genomic imprinting on brain
... loci, important in tissue functioning but not resource acquisition, that would function to decrease the costs associated with the hypothesized paternally expressed alleles (Haig & Westoby, 1989). As an illustration, if the genes involved in suckling are paternally expressed and maternally silent, ge ...
... loci, important in tissue functioning but not resource acquisition, that would function to decrease the costs associated with the hypothesized paternally expressed alleles (Haig & Westoby, 1989). As an illustration, if the genes involved in suckling are paternally expressed and maternally silent, ge ...
Johanson-Blizzard syndrome: a report of gender
... in the UBR1 gene. The different outcomes presented by these siblings from the same family, and most likely with the same mutation (molecular confirmation was not possible for the female twin), were mainly determined by early initiation of nutritional support and pancreatic enzyme replacement, making ...
... in the UBR1 gene. The different outcomes presented by these siblings from the same family, and most likely with the same mutation (molecular confirmation was not possible for the female twin), were mainly determined by early initiation of nutritional support and pancreatic enzyme replacement, making ...
Linkage Introduction
... chromosome, there is a deviation from this relationship. This deviation is summarized by the recombination fraction. The recombination fraction is often denoted by θ where 0 6 θ 6 12 P(recombinant gamete)= θ If θ < 21 , the loci are said to be linked or in genetic linkage When loci are completely li ...
... chromosome, there is a deviation from this relationship. This deviation is summarized by the recombination fraction. The recombination fraction is often denoted by θ where 0 6 θ 6 12 P(recombinant gamete)= θ If θ < 21 , the loci are said to be linked or in genetic linkage When loci are completely li ...
final_report_columns
... related sequences that may share similar function to the query sequence , (3) obtains the alignment of these chosen sequences, and (4) calculates normalized probabilities for all possible substitutions from the alignment. Positions with normalized probabilities less than 0.05 are predicted to be del ...
... related sequences that may share similar function to the query sequence , (3) obtains the alignment of these chosen sequences, and (4) calculates normalized probabilities for all possible substitutions from the alignment. Positions with normalized probabilities less than 0.05 are predicted to be del ...
Practical exon and gene quantification in R
... Ex 1) For how many regions are described in the GTF file? (the dimensions of a data.frame can be queried with the nrow and ncol functions) The first, third, fourth, fifth, and ninth columns are of particular interest as these contain the chromosome, element type, start, end and name of the various e ...
... Ex 1) For how many regions are described in the GTF file? (the dimensions of a data.frame can be queried with the nrow and ncol functions) The first, third, fourth, fifth, and ninth columns are of particular interest as these contain the chromosome, element type, start, end and name of the various e ...
Epigenetics: Histone Modification III
... Position-effect variegation (PEV) - Large segments of eukaryotic genomes are made of repetitive sequences that are constitutively heterochromatin - Juxtaposition of a gene to the heterochromatic regions derives PEV. - Spreading heterochromatic features to a nearby gene in a clonal fashion. - The dr ...
... Position-effect variegation (PEV) - Large segments of eukaryotic genomes are made of repetitive sequences that are constitutively heterochromatin - Juxtaposition of a gene to the heterochromatic regions derives PEV. - Spreading heterochromatic features to a nearby gene in a clonal fashion. - The dr ...
Chapter 1 - Online Open Genetics
... the phenotype that results will be that of the action of one “type” of protein, even if though there are two copies of the gene – they are both the same allele. There’s no real interaction because the proteins do the same thing. It’s in heterozygotes that we can see whether a Figure 1-2 particular a ...
... the phenotype that results will be that of the action of one “type” of protein, even if though there are two copies of the gene – they are both the same allele. There’s no real interaction because the proteins do the same thing. It’s in heterozygotes that we can see whether a Figure 1-2 particular a ...
Human fetal normal cDNA panel
... MgCl2, 10mM DTT). The estimated cDNA concentration is about 5.5ng/µl. 1µl cDNA is good enough for one PCR reaction. The 5' end of human clathrin cDNA (a 6 kb gene) has been amplified by PCR from all of these cDNAs. ...
... MgCl2, 10mM DTT). The estimated cDNA concentration is about 5.5ng/µl. 1µl cDNA is good enough for one PCR reaction. The 5' end of human clathrin cDNA (a 6 kb gene) has been amplified by PCR from all of these cDNAs. ...
Rates and patterns of chromosome evolution in enteric bacteria
... timescale. Short-term rates of chromosome evolution have been analyzed in experimental populations of E. coli B propagated for 2000 generations under four different thermal regimes: 32°C, 37°C, 42°C, and alternating 32°C and 42°C. In an analysis of these lines, chromosome alterations were monitored ...
... timescale. Short-term rates of chromosome evolution have been analyzed in experimental populations of E. coli B propagated for 2000 generations under four different thermal regimes: 32°C, 37°C, 42°C, and alternating 32°C and 42°C. In an analysis of these lines, chromosome alterations were monitored ...
genetics - Gene In The Title
... Two teams have independently decoded the entire genome of patients to find the exact genetic cause of their diseases. This approach could offer a start in the so far disappointing effort to identify the genetic roots of major killers: heart disease, diabetes and Alzheimer’s. http://www.nytimes.com/ ...
... Two teams have independently decoded the entire genome of patients to find the exact genetic cause of their diseases. This approach could offer a start in the so far disappointing effort to identify the genetic roots of major killers: heart disease, diabetes and Alzheimer’s. http://www.nytimes.com/ ...
A series of promoters for constitutive expression of heterologous
... in YE medium containing intrinsic thiamine, which is commonly used for yeast cell culture. Therefore, this property of the nmt1 promoter may limit the area of research in some cases. In addition to these inducible promoters, the adh1 promoter has been used in a number of expression vectors, and its ...
... in YE medium containing intrinsic thiamine, which is commonly used for yeast cell culture. Therefore, this property of the nmt1 promoter may limit the area of research in some cases. In addition to these inducible promoters, the adh1 promoter has been used in a number of expression vectors, and its ...
Document
... outcome of a sequencing project are masses of raw data The challenge is to turn these raw data into biological knowledge A valuable tool for this challenge is an automated diagnostic pipe through which newly determined sequences can be streamlined ...
... outcome of a sequencing project are masses of raw data The challenge is to turn these raw data into biological knowledge A valuable tool for this challenge is an automated diagnostic pipe through which newly determined sequences can be streamlined ...
Polypeptide Synthesis - Fairfax Senior High School
... Why does the original mRNA molecule break up into ...
... Why does the original mRNA molecule break up into ...
Mitosis in Drosophila
... 1986). Studies of the phenotypes of these mutants either singly, or as double mutant combinations, have enabled functional relationships between various mutants to be determined. The interrelationships between these genes are formally expressed as pathways of sequential activities. Several observati ...
... 1986). Studies of the phenotypes of these mutants either singly, or as double mutant combinations, have enabled functional relationships between various mutants to be determined. The interrelationships between these genes are formally expressed as pathways of sequential activities. Several observati ...
Applied and Environmental Microbiology
... Archaeoglobus fulgidus (16). Form IV is designated a RubisCOlike protein, as its sequence is most closely related to RubisCO but it is not involved in the Calvin cycle. The large subunit of form I RubisCO is encoded by the cbbL gene (18). The cbbL gene is 1,400 bp long and thus is large enough for u ...
... Archaeoglobus fulgidus (16). Form IV is designated a RubisCOlike protein, as its sequence is most closely related to RubisCO but it is not involved in the Calvin cycle. The large subunit of form I RubisCO is encoded by the cbbL gene (18). The cbbL gene is 1,400 bp long and thus is large enough for u ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.