X-Chromosome dosage compensation
... In C. elegans, the processes of dosage compensation and sex determination are coordinately regulated by a group of genes that respond to the primary sex-determination signal. Following this common step of regulation, sex determination and dosage compensation are separately controlled by distinct gen ...
... In C. elegans, the processes of dosage compensation and sex determination are coordinately regulated by a group of genes that respond to the primary sex-determination signal. Following this common step of regulation, sex determination and dosage compensation are separately controlled by distinct gen ...
Cold-induced silencing by long antisense transcripts of an
... is mostly unknown1. We are investigating the link between noncoding RNA and chromatin regulation through analysis of FLC — a regulator of flowering time in Arabidopsis and a target of several chromatin pathways. Here we use an unbiased strategy to characterize non-coding transcripts of FLC and show ...
... is mostly unknown1. We are investigating the link between noncoding RNA and chromatin regulation through analysis of FLC — a regulator of flowering time in Arabidopsis and a target of several chromatin pathways. Here we use an unbiased strategy to characterize non-coding transcripts of FLC and show ...
trigger - Bioconductor
... Description This R package provides tools for the statistical analysis of integrative genomic data that involve some combination of: genotypes, high-dimensional intermediate traits (e.g., gene expression, protein abundance), and higher-order traits (phenotypes). The package includes functions to: (1 ...
... Description This R package provides tools for the statistical analysis of integrative genomic data that involve some combination of: genotypes, high-dimensional intermediate traits (e.g., gene expression, protein abundance), and higher-order traits (phenotypes). The package includes functions to: (1 ...
Taxonomic evaluation of the Streptomyces griseus clade using
... from 0.001 to 0.010 within individual clusters. It was also shown that the bootstrap support for the 16S rRNA gene tree was generally low, especially for the deeper nodes. PCR amplification and sequencing of the atpD, gyrB, recA, rpoB and trpB genes were successful for the 18 additional strains. Gen ...
... from 0.001 to 0.010 within individual clusters. It was also shown that the bootstrap support for the 16S rRNA gene tree was generally low, especially for the deeper nodes. PCR amplification and sequencing of the atpD, gyrB, recA, rpoB and trpB genes were successful for the 18 additional strains. Gen ...
Interleukin?1 gene cluster variants with innate cytokine production
... that ex vivo production of the cytokines IL-1, IL-1Ra, tumor necrosis factor ␣ (TNF␣), and IL-10 varies by 60–70% based on heritability alone (7). Subjects can thus be characterized as high (proinflammatory) or low (antiinflammatory) producers based on these cytokine profiles (8,9). Such a characte ...
... that ex vivo production of the cytokines IL-1, IL-1Ra, tumor necrosis factor ␣ (TNF␣), and IL-10 varies by 60–70% based on heritability alone (7). Subjects can thus be characterized as high (proinflammatory) or low (antiinflammatory) producers based on these cytokine profiles (8,9). Such a characte ...
Identity-by-descent filtering of exome sequence data for disease
... We model the exome sequencing results using an HMM that can transition between hidden (unobservable) states, each of which ‘emits’ observable tokens. The goal of HMMs is typically to predict the most likely sequence of hidden states that best explain the observed data. HMMs have been used in many ap ...
... We model the exome sequencing results using an HMM that can transition between hidden (unobservable) states, each of which ‘emits’ observable tokens. The goal of HMMs is typically to predict the most likely sequence of hidden states that best explain the observed data. HMMs have been used in many ap ...
bantam Encodes a Developmentally Regulated microRNA that
... temporally and spatially regulated in response to patterning cues. bantam microRNA simultaneously stimulates cell proliferation and prevents apoptosis. We identify the pro-apoptotic gene hid as a target for regulation by bantam miRNA, providing an explanation for bantam’s anti-apoptotic activity. In ...
... temporally and spatially regulated in response to patterning cues. bantam microRNA simultaneously stimulates cell proliferation and prevents apoptosis. We identify the pro-apoptotic gene hid as a target for regulation by bantam miRNA, providing an explanation for bantam’s anti-apoptotic activity. In ...
Complete comparative genomic analysis of two field isolates of
... also contains multiple deletions in the v90/4 genome. The largest deletion is a 1165 bp fragment that contains orf21 (bro-a) and a portion of orf20. An alignment of the v90/4 and v90/2 sequences around the junction regions of the 1165 bp deletion is shown in Fig. 3. The 1165 bp fragment contains a p ...
... also contains multiple deletions in the v90/4 genome. The largest deletion is a 1165 bp fragment that contains orf21 (bro-a) and a portion of orf20. An alignment of the v90/4 and v90/2 sequences around the junction regions of the 1165 bp deletion is shown in Fig. 3. The 1165 bp fragment contains a p ...
Balancing between respiration and fermentation - UvA-DARE
... environment.. They have developed specific regulatory systems to sense the presence, type and concentrationn of a carbon source in order to carry out the metabolic functions most appropriate too the situation (figure 1). This provides the yeast cell with energy and reducing equivalents in thee form ...
... environment.. They have developed specific regulatory systems to sense the presence, type and concentrationn of a carbon source in order to carry out the metabolic functions most appropriate too the situation (figure 1). This provides the yeast cell with energy and reducing equivalents in thee form ...
Rhizobium Nodulation Protein NodC Is an Important Determinant of
... strains with R. meliloti and R. loti NodC, producing chitintetraose and chitinpentaose, respectively. In vitro experiments, using UDP-[14C]GlcNAc as a precursor, show that this difference reflects intrinsic properties of these NodC proteins and that it is not influenced by the UDP-GlcNAc concentrati ...
... strains with R. meliloti and R. loti NodC, producing chitintetraose and chitinpentaose, respectively. In vitro experiments, using UDP-[14C]GlcNAc as a precursor, show that this difference reflects intrinsic properties of these NodC proteins and that it is not influenced by the UDP-GlcNAc concentrati ...
What determines a leaf`s shape? | SpringerLink
... maturation until final shape is achieved. We found that the underlying factors governing these processes are inherently genetic: PIN1 and KNOX1 are indicators of leaf initiation, HD-ZIPIII, KANADI, and YABBY specify leaf outgrowth while ANGUSTIFOLIA3 and GROWTH-REGULATING FACTOR5 control leaf expans ...
... maturation until final shape is achieved. We found that the underlying factors governing these processes are inherently genetic: PIN1 and KNOX1 are indicators of leaf initiation, HD-ZIPIII, KANADI, and YABBY specify leaf outgrowth while ANGUSTIFOLIA3 and GROWTH-REGULATING FACTOR5 control leaf expans ...
Chapter 2 - psychpro.us
... • Genome-wide association method - Identify genetic variations linked to a particular disease • Human genome consists of many genes that collaborate: – Both with each other and with nongenetic factors inside and outside the body ...
... • Genome-wide association method - Identify genetic variations linked to a particular disease • Human genome consists of many genes that collaborate: – Both with each other and with nongenetic factors inside and outside the body ...
The virulence plasmids of Salmonella
... The exact role of the virulence plasmid in pathogenesis is unclear. Evidence exists that spv genes enable S. typhimurium to infect the spleen and the liver by increasing the rate of bacterial replication within host cells [22]. Plasmid-cured strains are able to colonize and persist in the spleen and ...
... The exact role of the virulence plasmid in pathogenesis is unclear. Evidence exists that spv genes enable S. typhimurium to infect the spleen and the liver by increasing the rate of bacterial replication within host cells [22]. Plasmid-cured strains are able to colonize and persist in the spleen and ...
Mice 2 NZW)F Genetic Complementation in Female (BXSB ×
... loci for the Yaa⫹ BXSB (possibly four regions on chromosome 1, possibly two on chromosome 4, and a single locus each on chromosomes 3, 7, 8, 10, 13, 14, and 17) (10 –12). Although some of the overlapping loci from different strains may represent the same gene, it is evident from this and other studi ...
... loci for the Yaa⫹ BXSB (possibly four regions on chromosome 1, possibly two on chromosome 4, and a single locus each on chromosomes 3, 7, 8, 10, 13, 14, and 17) (10 –12). Although some of the overlapping loci from different strains may represent the same gene, it is evident from this and other studi ...
Age-related macular degeneration: a perspective on genetic studies
... severe visual loss.1 As the disease primarily impacts on central vision, it is the leading cause of blindness in people above 60 years of age and accounts for about 50% of blind registration.2,3 A number of epidemiological studies have implicated AMD as an inherited disease showing that family membe ...
... severe visual loss.1 As the disease primarily impacts on central vision, it is the leading cause of blindness in people above 60 years of age and accounts for about 50% of blind registration.2,3 A number of epidemiological studies have implicated AMD as an inherited disease showing that family membe ...
Gregor Mendel and Genetics
... round seeds like one of the two parents. When the F1 generation plants self-pollinated, however, their offspring—the F2 generation—showed all possible combinations of the two characteristics. Some had green round seeds, for example, and some had yellow wrinkled seeds. These combinations of character ...
... round seeds like one of the two parents. When the F1 generation plants self-pollinated, however, their offspring—the F2 generation—showed all possible combinations of the two characteristics. Some had green round seeds, for example, and some had yellow wrinkled seeds. These combinations of character ...
Family Secrets Part 4 - University of Rochester Medical Center
... Testing for the HD Gene Narrator: Jenny, Jeremy, and their father have decided to undergo genetic testing for Huntington’s disease. Today, our lab groups will act as gene testing laboratory technicians. We will use the gel electrophoresis laboratory procedure to analyze the results of the simulated ...
... Testing for the HD Gene Narrator: Jenny, Jeremy, and their father have decided to undergo genetic testing for Huntington’s disease. Today, our lab groups will act as gene testing laboratory technicians. We will use the gel electrophoresis laboratory procedure to analyze the results of the simulated ...
pdf
... Nitrosococcus oceani strain ATCC 19707 was obtained from the American Type Culture Collection and maintained at a temperature of 30°C in the dark on marine medium as described previously (1, 40, 59). For the isolation of genomic DNA, cultures were grown in 0.6- and 1-liter batches of medium in 2- an ...
... Nitrosococcus oceani strain ATCC 19707 was obtained from the American Type Culture Collection and maintained at a temperature of 30°C in the dark on marine medium as described previously (1, 40, 59). For the isolation of genomic DNA, cultures were grown in 0.6- and 1-liter batches of medium in 2- an ...
Part 4 - URMC - University of Rochester
... Testing for the HD Gene Narrator: Jenny, Jeremy, and their father have decided to undergo genetic testing for Huntington’s disease. Today, our lab groups will act as gene testing laboratory technicians. We will use the gel electrophoresis laboratory procedure to analyze the results of the simulated ...
... Testing for the HD Gene Narrator: Jenny, Jeremy, and their father have decided to undergo genetic testing for Huntington’s disease. Today, our lab groups will act as gene testing laboratory technicians. We will use the gel electrophoresis laboratory procedure to analyze the results of the simulated ...
Slide 1
... During sexual reproduction, male and female reproductive cells join in a process known as fertilization to produce a new cell. In peas, this new cell develops into a tiny embryo encased within a seed. ...
... During sexual reproduction, male and female reproductive cells join in a process known as fertilization to produce a new cell. In peas, this new cell develops into a tiny embryo encased within a seed. ...
Vernalization Gene Architecture as a Predictor of Growth Habit in
... facultative forms can be planted in the fall or spring. Growth habit is important because it determines the range of adaptation. Winter and fall-sown facultative varieties generally yield more than spring-planted forms, provided that they have sufficient winter hardiness. However, a lack of winter ...
... facultative forms can be planted in the fall or spring. Growth habit is important because it determines the range of adaptation. Winter and fall-sown facultative varieties generally yield more than spring-planted forms, provided that they have sufficient winter hardiness. However, a lack of winter ...
Complex cocktails: the evolutionary novelty of venoms
... (Calloselasma rhodostoma) were demonstrated to correlate significantly with variation in the diet of the species. ...
... (Calloselasma rhodostoma) were demonstrated to correlate significantly with variation in the diet of the species. ...
Genomic dissection of plant development and its
... gain basic insights into the relationships between the different phases of plant development, HEI, and their influence on TGW. We observed very high correlations (0.88–0.93) between SHO, HEA, and MAT (Table 3). This indicates that early shooting lines also tend to be early for other stages. Another ...
... gain basic insights into the relationships between the different phases of plant development, HEI, and their influence on TGW. We observed very high correlations (0.88–0.93) between SHO, HEA, and MAT (Table 3). This indicates that early shooting lines also tend to be early for other stages. Another ...
Genetics text - Lyons USD 405
... Mendel’s work, titled Experiments in Plant Hybridization, was published in 1866, and sent to prominent libraries in several countries, as well as 133 natural science associations. Mendel himself even sent carefully marked experiment kits to Karl von Nageli, the leading botanist of the day. The resul ...
... Mendel’s work, titled Experiments in Plant Hybridization, was published in 1866, and sent to prominent libraries in several countries, as well as 133 natural science associations. Mendel himself even sent carefully marked experiment kits to Karl von Nageli, the leading botanist of the day. The resul ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.