The regulation of leukemia inhibitory factor
... regulates the embryonic stem cell self-renewal and is an indispensable factor to maintain mouse embryonic stem cell pluripotency [11]. Furthermore, LIF plays an important role in embryonic implantation. LIF regulates several events during implantation, which include the receptive state of endometria ...
... regulates the embryonic stem cell self-renewal and is an indispensable factor to maintain mouse embryonic stem cell pluripotency [11]. Furthermore, LIF plays an important role in embryonic implantation. LIF regulates several events during implantation, which include the receptive state of endometria ...
Mending Mendelism - SHiPS Resource Center
... in immune cells). Rather, they are expressed independently, in parallel. Others conceive dominance and recessiveness as the presence or absence of a trait, protein or gene product (e.g. Lewin 2000, p. 19). Here, one sees the phenotype as switched on or off. Geneticists in the early 1900s actively de ...
... in immune cells). Rather, they are expressed independently, in parallel. Others conceive dominance and recessiveness as the presence or absence of a trait, protein or gene product (e.g. Lewin 2000, p. 19). Here, one sees the phenotype as switched on or off. Geneticists in the early 1900s actively de ...
Chlamydia Exploit the Mammalian Tryptophan-Depletion
... proteins, whose extruded N-termini are important virulence factors. Although these N-termini ...
... proteins, whose extruded N-termini are important virulence factors. Although these N-termini ...
Chpt12_RNAProcessing.doc
... cleave a particular mRNA, thereby turning off expression of a particular gene. If over-expression or ectopic expression of a defined gene were the cause of some pathology (e.g. some form of cancer), then reducing its expression could have therapeutic value. Other RNAs possibly involved in catalysis, ...
... cleave a particular mRNA, thereby turning off expression of a particular gene. If over-expression or ectopic expression of a defined gene were the cause of some pathology (e.g. some form of cancer), then reducing its expression could have therapeutic value. Other RNAs possibly involved in catalysis, ...
Sun J, Ke J, Johnson JL, Nikolau BJ, Wurtele ES
... expressed GST-CAC2 fusion protein was used to generate antiserum (Fig. 2A). The resulting antiserum was used on western blots to identify the CAC2 protein in Arabidopsis leaf extracts (Fig. 2B). This anti-GST-CAC2 serum, but not the control preimmune serum, reacted solely with a 51-kD polypeptide, w ...
... expressed GST-CAC2 fusion protein was used to generate antiserum (Fig. 2A). The resulting antiserum was used on western blots to identify the CAC2 protein in Arabidopsis leaf extracts (Fig. 2B). This anti-GST-CAC2 serum, but not the control preimmune serum, reacted solely with a 51-kD polypeptide, w ...
View our poster (1.1 MB PDF)
... Figure 1. RNA interference (RNAi) is a highly evolutionarily conserved mechanism of gene regulation. RNAi occurs at the post-transcriptional level and is triggered by short double-stranded RNA (dsRNA), known as short interfering RNA (siRNA), which is endogenously processed from long dsRNA by the RNa ...
... Figure 1. RNA interference (RNAi) is a highly evolutionarily conserved mechanism of gene regulation. RNAi occurs at the post-transcriptional level and is triggered by short double-stranded RNA (dsRNA), known as short interfering RNA (siRNA), which is endogenously processed from long dsRNA by the RNa ...
Implementation of molecular markers for quantitative traits in
... donor parent. Young and Tanksley (1989) demonstrated that large amounts of donor parent chromosomal material can remain around a target gene even after many generations of conventional backcrossing. Since this surrounding material may contribute to “linkage drag,” especially if the donor parent is a ...
... donor parent. Young and Tanksley (1989) demonstrated that large amounts of donor parent chromosomal material can remain around a target gene even after many generations of conventional backcrossing. Since this surrounding material may contribute to “linkage drag,” especially if the donor parent is a ...
LEADING ARTICLE Concurrent disruption of p16INK4a and
... by DNA damage,33,34 results in apoptosis or cell growth arrest in both G1 and G2.33,35 ARF and p16INK4a are encoded by a single genetic locus, designated INK4a/ARF and located at chromosome 9p21.35–38 This locus consists of exon 1 specific for ARF, exon 1␣ specific for p16INK4a, and exons 2 and 3 c ...
... by DNA damage,33,34 results in apoptosis or cell growth arrest in both G1 and G2.33,35 ARF and p16INK4a are encoded by a single genetic locus, designated INK4a/ARF and located at chromosome 9p21.35–38 This locus consists of exon 1 specific for ARF, exon 1␣ specific for p16INK4a, and exons 2 and 3 c ...
THE GENETICS AND REPRODUCTIVE ISOLATING MECHANISMS
... The case of Pieris napi L. and bryonia? Ochsenheimer has wasted much ink in arguments among taxonomists as to whether bryonia: is a distinct species or only a subspecies of napi, without having brought about a satisfactory explanation. Even after the extensive work of MULLER and KAUTZ (1938), a turn ...
... The case of Pieris napi L. and bryonia? Ochsenheimer has wasted much ink in arguments among taxonomists as to whether bryonia: is a distinct species or only a subspecies of napi, without having brought about a satisfactory explanation. Even after the extensive work of MULLER and KAUTZ (1938), a turn ...
Gene Technology Regulation 2002
... Notifiable low risk dealings suitable for at least physical containment level 2 or 3 ...
... Notifiable low risk dealings suitable for at least physical containment level 2 or 3 ...
Youngson and Whitelaw, 2008
... during the lifetime of an organism. According to Lamarck, both environment and behavior direct organic change in an organism’s form and guide adaptation through the generations. A major problem with Lamarckian evolution, as pointed out initially by August Weismann in the nineteenth century, is the s ...
... during the lifetime of an organism. According to Lamarck, both environment and behavior direct organic change in an organism’s form and guide adaptation through the generations. A major problem with Lamarckian evolution, as pointed out initially by August Weismann in the nineteenth century, is the s ...
Student Handout
... teosinte and maize look like very different plants. It seemed unlikely that teosinte would give rise to maize within the 10,000 years or so that humans had been growing crops, because the process would involve changes in many genes—too many to occur in this time span. Dr. Beadle’s experiment set out ...
... teosinte and maize look like very different plants. It seemed unlikely that teosinte would give rise to maize within the 10,000 years or so that humans had been growing crops, because the process would involve changes in many genes—too many to occur in this time span. Dr. Beadle’s experiment set out ...
invited review
... human kidney cortex, and, to a much lesser degree, in the ileum (70, 71). Rat kidney SGLT1 and SGLT2 genes are transcribed in the cortex and the outer medulla, respectively (74). SGLT3 was isolated from a pig renal cell line by using our rabbit SGLT1 probe, and it was designated SAAT1 on the basis o ...
... human kidney cortex, and, to a much lesser degree, in the ileum (70, 71). Rat kidney SGLT1 and SGLT2 genes are transcribed in the cortex and the outer medulla, respectively (74). SGLT3 was isolated from a pig renal cell line by using our rabbit SGLT1 probe, and it was designated SAAT1 on the basis o ...
Genetics - Brook Biology
... Gene Expression Multicellular organisms need a variety of cell types to perform specific functions for the organism; therefore, individual cells differentiate and become specialized in structure and function. • Differentiation happens due to selective gene expression – some genes are turned off, ...
... Gene Expression Multicellular organisms need a variety of cell types to perform specific functions for the organism; therefore, individual cells differentiate and become specialized in structure and function. • Differentiation happens due to selective gene expression – some genes are turned off, ...
no isthmus and pax2.1 in zebrafish tubulogenesis
... pax5 and pax8 genes have been grouped into a common subfamily based on their sequence similarity and expression pattern. pax2/pax5/pax8 members share in common the paired domain, an octapeptide motif, and a partial homeodomain. Mice homozygous for a null mutation in pax2 display severe defects in ge ...
... pax5 and pax8 genes have been grouped into a common subfamily based on their sequence similarity and expression pattern. pax2/pax5/pax8 members share in common the paired domain, an octapeptide motif, and a partial homeodomain. Mice homozygous for a null mutation in pax2 display severe defects in ge ...
Practice final key
... the F1 progeny have purple-flowers. What can you conclude? (3 pts) Purple is dominant over white. b) The F1 progeny are allowed to self-fertilize. What phenotypic ratios do you expect in the F2 progeny? (3 pts) 3 Purple: 1 White “3:1” without specifying which (2 pts) c) Around 1900, Bateson, Saunder ...
... the F1 progeny have purple-flowers. What can you conclude? (3 pts) Purple is dominant over white. b) The F1 progeny are allowed to self-fertilize. What phenotypic ratios do you expect in the F2 progeny? (3 pts) 3 Purple: 1 White “3:1” without specifying which (2 pts) c) Around 1900, Bateson, Saunder ...
Chapter 14 Mendel and the Gene Idea Multiple-Choice
... Chapter 14 Mendel and the Gene Idea Multiple-Choice Questions 1) Pea plants were particularly well suited for use in Mendelʹs breeding experiments for all of the following reasons except that A) peas show easily observed variations in a number of characters, such as pea shape and flower color. B) it ...
... Chapter 14 Mendel and the Gene Idea Multiple-Choice Questions 1) Pea plants were particularly well suited for use in Mendelʹs breeding experiments for all of the following reasons except that A) peas show easily observed variations in a number of characters, such as pea shape and flower color. B) it ...
SLOs - 3.3 Genetics small - Miss Jan`s Science Wikispace
... State some examples of mutagenic agents Explain how these mutagenic agents cause mutations 3. To learn about the effects of mutations Explain why somatic mutations have less significant impact on a species than those that occur in gametes Explain why most mutations are not expressed Explai ...
... State some examples of mutagenic agents Explain how these mutagenic agents cause mutations 3. To learn about the effects of mutations Explain why somatic mutations have less significant impact on a species than those that occur in gametes Explain why most mutations are not expressed Explai ...
CIRCADIAN RHYTHMS IN PLANTS C Robertson McClung
... are unsuitable for circadian studies. Even though mRNA abundance oscillates in response to clock-gated transcription, the reporter activity (e.g. β-glucuronidase or chloramphenicol acetyltransferase) is too stable to allow turnover within a circadian cycle, and the accumulation of reporter activity ...
... are unsuitable for circadian studies. Even though mRNA abundance oscillates in response to clock-gated transcription, the reporter activity (e.g. β-glucuronidase or chloramphenicol acetyltransferase) is too stable to allow turnover within a circadian cycle, and the accumulation of reporter activity ...
Inheritance involved in the pathogenesis of idiopathic scoliosis
... Radiation therapy, tumors and syrinx formation have also been implicated as etiologies of scoliosis (Richards and Vitale, 2008). To date, the genetics underlying idiopathic curvature have not been identified. This is most likely a consequence of several factors, including inconsistent pedigree const ...
... Radiation therapy, tumors and syrinx formation have also been implicated as etiologies of scoliosis (Richards and Vitale, 2008). To date, the genetics underlying idiopathic curvature have not been identified. This is most likely a consequence of several factors, including inconsistent pedigree const ...
Gregor Mendel was a 19th century priest and botanist who
... o Dunn (1965), under the assumption that Mendel studied one gene on each of the seven chromosomes, calculated the probability of doing so as 6/7 x 5/7 x 4/7 x 3/7 x 2/7 x 1/7 = 0.0061 (<1%), again calling Mendel's experimental results into question. Mendel studied: http://www.jic.bbsrc.ac.uk/germpla ...
... o Dunn (1965), under the assumption that Mendel studied one gene on each of the seven chromosomes, calculated the probability of doing so as 6/7 x 5/7 x 4/7 x 3/7 x 2/7 x 1/7 = 0.0061 (<1%), again calling Mendel's experimental results into question. Mendel studied: http://www.jic.bbsrc.ac.uk/germpla ...
Full text PDF
... specified before being deployed in Markers Assisted Selection (MAS). It could be argued that specific SSR haplotypes associated with Xgwm44 and Xgwm111 for Dn ...
... specified before being deployed in Markers Assisted Selection (MAS). It could be argued that specific SSR haplotypes associated with Xgwm44 and Xgwm111 for Dn ...
11-4 Meiosis - Midland Park School District
... that the farther apart two genes were on a chromosome, the more likely it would be that a crossover event would occur between them. If two genes are close together, then crossovers between them should be rare. If two genes are far apart, then crossovers between them should be more common. ...
... that the farther apart two genes were on a chromosome, the more likely it would be that a crossover event would occur between them. If two genes are close together, then crossovers between them should be rare. If two genes are far apart, then crossovers between them should be more common. ...
INHERITANCE OF POLYDACTYLY IN THE MOUSE
... of polydactyls are as follows: 75.6f 2.4 for litters born when dams (and sires) one to 4 months of age; 77.3 A 1.9, for 5 to 7 months of age; and 75.0 A 3.6, for 8 to 11 months of age. Matings in this line usually were not continued to the reproductive limit since the practice has been to discontinu ...
... of polydactyls are as follows: 75.6f 2.4 for litters born when dams (and sires) one to 4 months of age; 77.3 A 1.9, for 5 to 7 months of age; and 75.0 A 3.6, for 8 to 11 months of age. Matings in this line usually were not continued to the reproductive limit since the practice has been to discontinu ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.