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FinalPresentation_ccb2012_marc_shangying_yan
... Inhibition of HER2 signaling to apoptotic transcription factors is studied. Models with different complexities are analyzed. Laptinib induced inhibition of HER2 is simulated. Outlook Improve the stochastic study Improve the pathway model with more details by getting more rates from experim ...
... Inhibition of HER2 signaling to apoptotic transcription factors is studied. Models with different complexities are analyzed. Laptinib induced inhibition of HER2 is simulated. Outlook Improve the stochastic study Improve the pathway model with more details by getting more rates from experim ...
Tumour necrosis factor and lymphotoxin A progression? EDITORIAL
... in quitters and sustained smokers, might yield important information about pathophysiological mechanisms underlying the sex differences in susceptibility to cigarette smoke. In conclusion, TANAKA et al. [1] report, contrary to previously reported positive studies in Asians on chronic obstructive pul ...
... in quitters and sustained smokers, might yield important information about pathophysiological mechanisms underlying the sex differences in susceptibility to cigarette smoke. In conclusion, TANAKA et al. [1] report, contrary to previously reported positive studies in Asians on chronic obstructive pul ...
Engrailed cooperates with extradenticle and homothorax to repress
... boundaries during Drosophila development (Akam, 1987; Blair, 1995). Its homologs in mammals are important in brain and limb development, where they might provide a similar function (Augustine et al., 1995; Joyner, 1996; Wurst et al., 1994). The En gene product regulates several key target genes. It ...
... boundaries during Drosophila development (Akam, 1987; Blair, 1995). Its homologs in mammals are important in brain and limb development, where they might provide a similar function (Augustine et al., 1995; Joyner, 1996; Wurst et al., 1994). The En gene product regulates several key target genes. It ...
Perspectives in Diabetes Glucokinase Gene Structure
... nondiabetic animal do not substantially alter blood glucose concentrations. Nevertheless, both studies point to the importance of understanding how the tissue-specific differential regulation of glucokinase occurs, especially when the role of this enzyme in regulating glucose metabolism of the liver ...
... nondiabetic animal do not substantially alter blood glucose concentrations. Nevertheless, both studies point to the importance of understanding how the tissue-specific differential regulation of glucokinase occurs, especially when the role of this enzyme in regulating glucose metabolism of the liver ...
of Gray Alpacas - North Sound Alpaca Association
... most dark-headed roans have NO ROAN PARENTS. This is the classic sign of a recessive trait. For dominant traits, if you have the allele, you have the trait. Clearly, this is not the case for dark-headed roans. Breeding two dark-headed roans together should always yield more darkheaded roans (if it i ...
... most dark-headed roans have NO ROAN PARENTS. This is the classic sign of a recessive trait. For dominant traits, if you have the allele, you have the trait. Clearly, this is not the case for dark-headed roans. Breeding two dark-headed roans together should always yield more darkheaded roans (if it i ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... mixed till the pellet was dislodged and then 125l of 10% SDS was added, mixed gently again. The tubes were then incubated at 55o C in water bath for 10-20 minutes to lyse the WBC and release the DNA The contents were then transferred into sterile eppendorf tubes and 300l of 6M NaCl was added, mixe ...
... mixed till the pellet was dislodged and then 125l of 10% SDS was added, mixed gently again. The tubes were then incubated at 55o C in water bath for 10-20 minutes to lyse the WBC and release the DNA The contents were then transferred into sterile eppendorf tubes and 300l of 6M NaCl was added, mixe ...
Idic(15)
... instruction booklets (or recipes) that contain all the genetic information telling the body how to develop, grow and function. Chromosomes (and genes) usually come in pairs with one member of each chromosome pair being inherited from each parent. Humans have 23 pairs of chromosomes giving a total of ...
... instruction booklets (or recipes) that contain all the genetic information telling the body how to develop, grow and function. Chromosomes (and genes) usually come in pairs with one member of each chromosome pair being inherited from each parent. Humans have 23 pairs of chromosomes giving a total of ...
The cuticle
... The cuticle surrounding the main body of the animal can be sub-divided into the broad dorsal and ventral regions overlying the dorsal and ventral hypodermis and the narrow lateral regions overlying the seam cells where longitudinal ridges termed alae are positioned on the cuticle of the L1 and dauer ...
... The cuticle surrounding the main body of the animal can be sub-divided into the broad dorsal and ventral regions overlying the dorsal and ventral hypodermis and the narrow lateral regions overlying the seam cells where longitudinal ridges termed alae are positioned on the cuticle of the L1 and dauer ...
Chapter 15
... exhibited greater longevity than non-aa genotypes when reared on various concentrations of dry yeast in the food medium (Thomas, 1991). This life-span extension was observed for all yeast concentrations, except for the concentration used by Templeton (1982, 1983), which reduced life span. Thus, nutr ...
... exhibited greater longevity than non-aa genotypes when reared on various concentrations of dry yeast in the food medium (Thomas, 1991). This life-span extension was observed for all yeast concentrations, except for the concentration used by Templeton (1982, 1983), which reduced life span. Thus, nutr ...
Selection for TnlO Tet Repressor Binding to tet Operator
... We have constructed a genetic assay which selects positively for a functional interaction between Tet repressor and its cognate operator in Escherichia coli. In this strain Tet repressor blocks expression of lacl and lacZ. This leads to derepression of a lacPO controlled galK gene. The strain can be ...
... We have constructed a genetic assay which selects positively for a functional interaction between Tet repressor and its cognate operator in Escherichia coli. In this strain Tet repressor blocks expression of lacl and lacZ. This leads to derepression of a lacPO controlled galK gene. The strain can be ...
The enhancement of ribosomal transcription by the recycling of RNA
... Grummt et al. (10) and Henderson and Sollner-Webb (11), have recently identified a termination sequence at about 168 b.p., upstream of the pre-rRNA initiation site of the mouse rDNA. Both sets of authors find that deletion of this termination site reduces pre-rRNA initation at the adjacent promoter. ...
... Grummt et al. (10) and Henderson and Sollner-Webb (11), have recently identified a termination sequence at about 168 b.p., upstream of the pre-rRNA initiation site of the mouse rDNA. Both sets of authors find that deletion of this termination site reduces pre-rRNA initation at the adjacent promoter. ...
Mouse Lefty2 and Zebrafish Antivin Are Feedback
... no homozygous animals were found, indicating that lefty2 null mutants are embryonic lethal. To characterize the embryonic lethality, we initially analyzed litters from heterozygous intercrosses at embryonic days 8.0 (E8.0) to E11.5. At E8.25, homozygous mutant embryos were present at roughly the exp ...
... no homozygous animals were found, indicating that lefty2 null mutants are embryonic lethal. To characterize the embryonic lethality, we initially analyzed litters from heterozygous intercrosses at embryonic days 8.0 (E8.0) to E11.5. At E8.25, homozygous mutant embryos were present at roughly the exp ...
Foxf1 controls mesoderm differentiation
... *Author for correspondence (e-mail: [email protected]) ...
... *Author for correspondence (e-mail: [email protected]) ...
In vitro fertilization (IVF) in mammals: epigenetic and developmental
... different characters are transmitted from parents to offspring. But, Waddington underlined, that there wasn’t much knowledge about the mechanisms of development. He named this process Epigenetics, which is now understood as the conditions that control the expression of genes that are highly influenc ...
... different characters are transmitted from parents to offspring. But, Waddington underlined, that there wasn’t much knowledge about the mechanisms of development. He named this process Epigenetics, which is now understood as the conditions that control the expression of genes that are highly influenc ...
Seed Dormancy and Germination
... maintained in fus3 mutants but not in lec1, which suggests that these mutants affect the germination potential of seeds in different ways. Apart from mutants that influence general seed maturation, other mutants more specifically influence seed dormancy, i.e. mutants, which are altered in ABA biosyn ...
... maintained in fus3 mutants but not in lec1, which suggests that these mutants affect the germination potential of seeds in different ways. Apart from mutants that influence general seed maturation, other mutants more specifically influence seed dormancy, i.e. mutants, which are altered in ABA biosyn ...
No Slide Title
... Theory of Mind – able to reflect on the contents of one's own and other's minds. For many of those with autism or Asperger's, mindblindness, or lack of Theory of Mind creates major barriers to communication and closeness. These barriers often lead to those nearest to the individual feel, whether re ...
... Theory of Mind – able to reflect on the contents of one's own and other's minds. For many of those with autism or Asperger's, mindblindness, or lack of Theory of Mind creates major barriers to communication and closeness. These barriers often lead to those nearest to the individual feel, whether re ...
jing is required for wing development and to establish the
... Culi et al. Like most transcription factors, those that are required for PD axis formation in the Drosophila leg have additional and very distinct functions at other stages and tissues during development. For example, dac plays an important role in the development of the eye, central nervous system ...
... Culi et al. Like most transcription factors, those that are required for PD axis formation in the Drosophila leg have additional and very distinct functions at other stages and tissues during development. For example, dac plays an important role in the development of the eye, central nervous system ...
Pourcel et al., Microbiology 2005
... been found in all archaea and hyperthermophilic bacteria investigated so far and also in some eubacteria at one or several loci in the chromosome. Their structure is remarkably constant. They consist of repeated sequences, 21–37 bp in length, separated by similarly sized variable sequences or spacer ...
... been found in all archaea and hyperthermophilic bacteria investigated so far and also in some eubacteria at one or several loci in the chromosome. Their structure is remarkably constant. They consist of repeated sequences, 21–37 bp in length, separated by similarly sized variable sequences or spacer ...
Tomé, S., Manley, K., Simard, J.P., Clark, G.W., Slean, M.M., Swami
... of MutSb in expansions extends beyond its ability to bind slippedDNAs [50] as an ATPase-functional MutSb complex is necessary for CAG expansions [47] and downstream mismatch repair proteins, like PMS2 are partially required for instability [28]. The MutSb complex may act on CAG repeats during errors ...
... of MutSb in expansions extends beyond its ability to bind slippedDNAs [50] as an ATPase-functional MutSb complex is necessary for CAG expansions [47] and downstream mismatch repair proteins, like PMS2 are partially required for instability [28]. The MutSb complex may act on CAG repeats during errors ...
Cotyledon organogenesis - Journal of Experimental Botany
... never been entirely clear for some species of paleoherbs such as Nymphaea (Tillich, 1990), which has a single cotyledon with two lobes, which could also be interpreted as two fused cotyledons. It has been suggested that Nymphaea is a monocot (Titova and Batygina, 1986), although molecular studies co ...
... never been entirely clear for some species of paleoherbs such as Nymphaea (Tillich, 1990), which has a single cotyledon with two lobes, which could also be interpreted as two fused cotyledons. It has been suggested that Nymphaea is a monocot (Titova and Batygina, 1986), although molecular studies co ...
Exam Questions from Exam 1 – Basic Genetic Tests
... st– mutation are “stubby-legged” (wild-type flies are long-legged). You mate flies from two true-breeding strains, and the resulting F1 flies are all are straight-backed, smooth-winged, and long-legged. F1 females are then mated to males that are humpbacked, blistery-winged, and stubby-legged. In th ...
... st– mutation are “stubby-legged” (wild-type flies are long-legged). You mate flies from two true-breeding strains, and the resulting F1 flies are all are straight-backed, smooth-winged, and long-legged. F1 females are then mated to males that are humpbacked, blistery-winged, and stubby-legged. In th ...
LATHYROIDES, encoding a WUSCHEL
... Weng et al., 2011). In wild type, a representative cell type of dorsal petals is a long strip with wavy margins, one of the lateral petals is jigsaw puzzle-like, and the one of the ventral petals is ripple-like (Figure 5G). The dorsal petals of lst mutant exhibited the abnormal epidermal cells which ...
... Weng et al., 2011). In wild type, a representative cell type of dorsal petals is a long strip with wavy margins, one of the lateral petals is jigsaw puzzle-like, and the one of the ventral petals is ripple-like (Figure 5G). The dorsal petals of lst mutant exhibited the abnormal epidermal cells which ...
Gene interactions in the evolution of genomic imprinting
... reflect this pattern, we assign the same subscripts to those alleles that work best together. We focus on this form of epistasis because it does not contain any dominance effect, and therefore these models are not influenced by selection on dominance modification, discussed above. This model further ...
... reflect this pattern, we assign the same subscripts to those alleles that work best together. We focus on this form of epistasis because it does not contain any dominance effect, and therefore these models are not influenced by selection on dominance modification, discussed above. This model further ...
Gene expression profiling
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In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.