Chapter 4: Individual gene function
... Some loss-of-function alleles may still produce DNA, RNA, or protein, but still lack gene activity. This might happen if a gene lacks the ability to make the crucial functional domain of its product, it may not be able to function even if detectable protein product is present. For example, a gene en ...
... Some loss-of-function alleles may still produce DNA, RNA, or protein, but still lack gene activity. This might happen if a gene lacks the ability to make the crucial functional domain of its product, it may not be able to function even if detectable protein product is present. For example, a gene en ...
Operon Models
... 9. Place stick-on tabs on the parts of the operator and the repressor protein that fit together, so that they can stick together without being held in place. You may do the same for the repressor and the co-repressor/tryptophan ball. ...
... 9. Place stick-on tabs on the parts of the operator and the repressor protein that fit together, so that they can stick together without being held in place. You may do the same for the repressor and the co-repressor/tryptophan ball. ...
Design a Kid
... A. Determine the sex of your child. Flip the penny once to determine the chromosome inherited from the father. Flip the penny a second time to determine the chromosome inherited by the mother: ...
... A. Determine the sex of your child. Flip the penny once to determine the chromosome inherited from the father. Flip the penny a second time to determine the chromosome inherited by the mother: ...
Albinism - OG
... gene from the father and the albinism gene from the mother both have to passed on to the kid. The kid needs to have both albinism genes from each parent to have albinism, not just one. If they only have one albino gene, then the child will be considered a “carrier” of an albinism gene. Albinis ...
... gene from the father and the albinism gene from the mother both have to passed on to the kid. The kid needs to have both albinism genes from each parent to have albinism, not just one. If they only have one albino gene, then the child will be considered a “carrier” of an albinism gene. Albinis ...
The Toll immune-regulated Drosophila protein Fondue is involved in
... CG15825 (referred to as fon in this paper) is induced four-fold by septic injury with a mixture of Gram-positive and Gramnegative bacteria and also induced after natural infection by the entomopathogenic fungus Beauveria bassiana (De Gregorio et al., 2001). The expression profile in response to sept ...
... CG15825 (referred to as fon in this paper) is induced four-fold by septic injury with a mixture of Gram-positive and Gramnegative bacteria and also induced after natural infection by the entomopathogenic fungus Beauveria bassiana (De Gregorio et al., 2001). The expression profile in response to sept ...
An Analysis of the Arabidopsis Pollen
... Becker et al. (Becker et al., 2003) that used ATH8 microarrays covering about one-third of the Arabidopsis genome. In both studies, viable, hydrated pollen grains were sorted from other pollen stages and cell debris with flow cytometry. Using ATH1 microarrays, representing 22,750 annotated genes, Pi ...
... Becker et al. (Becker et al., 2003) that used ATH8 microarrays covering about one-third of the Arabidopsis genome. In both studies, viable, hydrated pollen grains were sorted from other pollen stages and cell debris with flow cytometry. Using ATH1 microarrays, representing 22,750 annotated genes, Pi ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... Astanand Jugessur ,Fedik Rahimov , Jeffrey C.Murray Genetic variants in IRF6 and risk of facial clefts: single marker and haplotype-based analyses in a population-based case control study of facial clefts in Norway. 2008 DOI: 10.1002/gepi.20314 Alexandre R Viera , Joseph R Avila , Jill Harrington Me ...
... Astanand Jugessur ,Fedik Rahimov , Jeffrey C.Murray Genetic variants in IRF6 and risk of facial clefts: single marker and haplotype-based analyses in a population-based case control study of facial clefts in Norway. 2008 DOI: 10.1002/gepi.20314 Alexandre R Viera , Joseph R Avila , Jill Harrington Me ...
Triple-hit lymphoma
... (2). Translocation of the BCL-2 gene on chromosome 18q21 results in constant inactivation of apoptosis (3). Translocation of the c-MYC gene on chromosome 8q24 results in constant cell proliferation (3). These double-hit lymphomas are associated with an aggressive clinical course, with poor response ...
... (2). Translocation of the BCL-2 gene on chromosome 18q21 results in constant inactivation of apoptosis (3). Translocation of the c-MYC gene on chromosome 8q24 results in constant cell proliferation (3). These double-hit lymphomas are associated with an aggressive clinical course, with poor response ...
Molecular Mechanisms of Floral Boundary Formation in Arabidopsis
... of the ARGONAUTE family that acts in small RNA pathways [54–56], and the genes required for organ primordia development, including BOP2 and JAGGED (JAG), a C2H2 zinc finger transcriptional factor that promotes cell division and growth of lateral organs [53,57,58]. These interactions promote the func ...
... of the ARGONAUTE family that acts in small RNA pathways [54–56], and the genes required for organ primordia development, including BOP2 and JAGGED (JAG), a C2H2 zinc finger transcriptional factor that promotes cell division and growth of lateral organs [53,57,58]. These interactions promote the func ...
The Biological Performance of Calcium Hydroxide
... reaction. RNA was extracted using Trizol according to the manufacturer’s instructions and was reverse transcribed to complementary DNA using a reverse transcription kit (Fermentas, Vilnius, Lithuania). Real-time PCR reactions were performed using Faststart Universal SYBR Green Master (Rox; Roche, Ba ...
... reaction. RNA was extracted using Trizol according to the manufacturer’s instructions and was reverse transcribed to complementary DNA using a reverse transcription kit (Fermentas, Vilnius, Lithuania). Real-time PCR reactions were performed using Faststart Universal SYBR Green Master (Rox; Roche, Ba ...
What is meant by the term monogenic? What`s probability got to do
... identified gene homologs in Pisum sativum (pea), Arabidopsis thaliana, and Festuca pratensis (meadow fescue), mutations of which partially disable plant senescence. The biochemical properties and map location of this gene in pea indicate that it is the same locus that determines yellow (I) and green ...
... identified gene homologs in Pisum sativum (pea), Arabidopsis thaliana, and Festuca pratensis (meadow fescue), mutations of which partially disable plant senescence. The biochemical properties and map location of this gene in pea indicate that it is the same locus that determines yellow (I) and green ...
Professor Anthony Monaco - AWARES, the All Wales Autism Resource
... Are autism associated CNVs more likely to be sporadic “mutations” or inherited risk factors? ...
... Are autism associated CNVs more likely to be sporadic “mutations” or inherited risk factors? ...
Neema Bhukhan
... identical patterns of non-coding sequence conservation in human, dog, and mouse DNA. Of the 14 conserved non-coding sequences found, 2 were determined to be gene regulatory elements. The results they obtained suggest that a large fraction of non-coding elements identified are conserved because of fu ...
... identical patterns of non-coding sequence conservation in human, dog, and mouse DNA. Of the 14 conserved non-coding sequences found, 2 were determined to be gene regulatory elements. The results they obtained suggest that a large fraction of non-coding elements identified are conserved because of fu ...
Intelligent Systems and Bioinformatics Laboratory
... (2) The Tree View does not display the entire GO tree. It only displays the terms and their parent terms from the GO tree for which the total number of genes found in the input list is not zero. The Synchronized View is a bar graph that is synchronized with the Tree View. It is synchronized with the ...
... (2) The Tree View does not display the entire GO tree. It only displays the terms and their parent terms from the GO tree for which the total number of genes found in the input list is not zero. The Synchronized View is a bar graph that is synchronized with the Tree View. It is synchronized with the ...
Maternal-Effect Genes That Alter the Fate Map of the Drosophila
... wild-type embryo at the cellular blastoderm stage (3 hr) exhibits seven stripes offtz protein. (b) A wild-type embryo at the end of embryogenesis (22 hr). Some segments are indicated. T, thoracic; A, abdominal; tl, telson. (c) vdpD/vc&? The broad region offtz staining that occurs in place of stripes ...
... wild-type embryo at the cellular blastoderm stage (3 hr) exhibits seven stripes offtz protein. (b) A wild-type embryo at the end of embryogenesis (22 hr). Some segments are indicated. T, thoracic; A, abdominal; tl, telson. (c) vdpD/vc&? The broad region offtz staining that occurs in place of stripes ...
Figures and figure supplements
... and a loss of G418 resistance. (B) Quantitative RT-PCR analysis of α1 and α2 mRNA levels in a strain containing wild-type HMLα (JRY9623), and α1 and cre mRNA levels in a strain containing HMLα::cre (JRY9625). To determine the fold repression, mRNA levels were also measured in HMLα and HMLα::cre stra ...
... and a loss of G418 resistance. (B) Quantitative RT-PCR analysis of α1 and α2 mRNA levels in a strain containing wild-type HMLα (JRY9623), and α1 and cre mRNA levels in a strain containing HMLα::cre (JRY9625). To determine the fold repression, mRNA levels were also measured in HMLα and HMLα::cre stra ...
BLSSpeller: exhaustive comparative discovery of
... definition of conservation was previously used by Gordân et al. (2010) and is especially relevant when studying more diverged species for which accurate multiple sequence alignments are difficult to generate. Alignment-based discovery adds the constraint that motifs must be aligned, i.e. occur at t ...
... definition of conservation was previously used by Gordân et al. (2010) and is especially relevant when studying more diverged species for which accurate multiple sequence alignments are difficult to generate. Alignment-based discovery adds the constraint that motifs must be aligned, i.e. occur at t ...
GST SF in E. coli - Institute for Genomic Biology
... Taking advantage of existing samples… Noncovalent Protein: Ligand Interactions Measured by Native ESI-MS (from test cases to EFI samples…) ...
... Taking advantage of existing samples… Noncovalent Protein: Ligand Interactions Measured by Native ESI-MS (from test cases to EFI samples…) ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.