Variable Autosomal and X Divergence Near and Far from Genes
... Male mutation bias, when more mutations are passed on via the male germline than via the female germline, is observed across mammals. One common way to infer the magnitude of male mutation bias, a, is to compare levels of neutral sequence divergence between genomic regions that spend different amoun ...
... Male mutation bias, when more mutations are passed on via the male germline than via the female germline, is observed across mammals. One common way to infer the magnitude of male mutation bias, a, is to compare levels of neutral sequence divergence between genomic regions that spend different amoun ...
Journal of Bacteriology
... ropA encodes a 36-kDa outer membrane protein of Rhizobium leguminosarum bv. viciae strain 248 which constitutes the low-Mr part of antigen group III (R. A. de Maagd, I. H. M. Mulders, H. C. J. Canter Cremers, and B. J. J. Lugtenberg, J. Bacteriol. 174:214–221, 1992). We observed that genes homologou ...
... ropA encodes a 36-kDa outer membrane protein of Rhizobium leguminosarum bv. viciae strain 248 which constitutes the low-Mr part of antigen group III (R. A. de Maagd, I. H. M. Mulders, H. C. J. Canter Cremers, and B. J. J. Lugtenberg, J. Bacteriol. 174:214–221, 1992). We observed that genes homologou ...
One gene, many neuropsychiatric disorders
... multiple diseases is closely associated with the concept of an allelic series. As formulated by Victor A. McKusick in 1973, the term allelic series describes disease phenotypes that are seemingly caused by different genes on clinical grounds, but with genetic and/or biochemical evidence supporting m ...
... multiple diseases is closely associated with the concept of an allelic series. As formulated by Victor A. McKusick in 1973, the term allelic series describes disease phenotypes that are seemingly caused by different genes on clinical grounds, but with genetic and/or biochemical evidence supporting m ...
(COX2) gene in giant panda, Ailuropoda melanoleuca
... complete mitochondrial genome of giant panda as reported (Peng et al., 2007) and with those deposited in GenBank, as the BLAST results revealed 100% sequence identity. Although some mutations were detected in the COX2 sequences, none of those mutations caused changes in the amino acids, and hence th ...
... complete mitochondrial genome of giant panda as reported (Peng et al., 2007) and with those deposited in GenBank, as the BLAST results revealed 100% sequence identity. Although some mutations were detected in the COX2 sequences, none of those mutations caused changes in the amino acids, and hence th ...
Introduction - Society for the Advancement of American Philosophy
... Dewey's understanding of nature includes a constantly evolving trajectory, as the environment changes the definition of an adapted and adapting individual changes to suit it. The connection between growth and education is more than analogy for Dewey. Dewey defines education as a “continuous process ...
... Dewey's understanding of nature includes a constantly evolving trajectory, as the environment changes the definition of an adapted and adapting individual changes to suit it. The connection between growth and education is more than analogy for Dewey. Dewey defines education as a “continuous process ...
Basic Concepts in the Study of Diseases with Complex Genetics
... down a small region on the chromosome where the gene is located. If that is feasible, the steps that follow, namely cloning of the region and identifying every gene within the linked region, albeit hard work, have become easier and more straightforward (Collins 1995). With the advances of the Human ...
... down a small region on the chromosome where the gene is located. If that is feasible, the steps that follow, namely cloning of the region and identifying every gene within the linked region, albeit hard work, have become easier and more straightforward (Collins 1995). With the advances of the Human ...
Maternal and paternal genomes contribute equally to the
... than the sperm (Fig. 1b). In addition, 543 transcripts had at least fourfold higher reads per million (genome- and cDNA-matching reads) values at the 8-cell stage than at the 1-cell/2-cell stages, which suggested active transcription of the corresponding genes between the 1-cell/2cell and 8-cell sta ...
... than the sperm (Fig. 1b). In addition, 543 transcripts had at least fourfold higher reads per million (genome- and cDNA-matching reads) values at the 8-cell stage than at the 1-cell/2-cell stages, which suggested active transcription of the corresponding genes between the 1-cell/2cell and 8-cell sta ...
KNOX1 genes regulate lignin deposition and composition
... including cellulose, hemicellulose, and lignin. Lignin functions primarily to maintain the structural and mechanical integrity of both the transport vessel and the entire plant itself. Since lignin has been identified as a major source of biomass for biofuels, regulation of secondary cell wall biosyn ...
... including cellulose, hemicellulose, and lignin. Lignin functions primarily to maintain the structural and mechanical integrity of both the transport vessel and the entire plant itself. Since lignin has been identified as a major source of biomass for biofuels, regulation of secondary cell wall biosyn ...
The linear chromosome of the plant
... and psyllids (Psyllidae) [1]. Phytoplasmas were recently assigned to the novel provisional genus Candidatus Phytoplasma [2]. They represent a monophyletic group within the class Mollicutes (trivial name mycoplasmas), which has evolved from Gram-positive bacteria [3]. Mycoplasmas are among the smalle ...
... and psyllids (Psyllidae) [1]. Phytoplasmas were recently assigned to the novel provisional genus Candidatus Phytoplasma [2]. They represent a monophyletic group within the class Mollicutes (trivial name mycoplasmas), which has evolved from Gram-positive bacteria [3]. Mycoplasmas are among the smalle ...
Analysis of alternative splicing in Drosophila genetic
... natural physiological context and simultaneous observations can be made on a variety of tissues. In cases where splicing is developmentally regulated, the ability to monitor splicing over time in differentiating tissues has the potential to reveal information about the dynamics of splicing factor fu ...
... natural physiological context and simultaneous observations can be made on a variety of tissues. In cases where splicing is developmentally regulated, the ability to monitor splicing over time in differentiating tissues has the potential to reveal information about the dynamics of splicing factor fu ...
DNA sequencing revealed a definitive
... Figure 4. Similarity matrix for the amino acid sequences of the homeo domains of iab-7 and its deuterostome cognates. Numbers represent % aa positional identity, which is 100 x the number of matched aa/60 aa. 72% aa positional identity, respectively (26,28,30,31,32). Also, the HB4 homeo domain share ...
... Figure 4. Similarity matrix for the amino acid sequences of the homeo domains of iab-7 and its deuterostome cognates. Numbers represent % aa positional identity, which is 100 x the number of matched aa/60 aa. 72% aa positional identity, respectively (26,28,30,31,32). Also, the HB4 homeo domain share ...
Identification of a Class of Chromatin Boundary Elements
... after five cycles of the enrichment protocol (see below) and selected by alpha complementation. From 101 plasmids, 11 cBEs were obtained, and of these, 4 had sequences related to cBE28. Both strands of the cBEs were dideoxy sequenced, and sequence comparisons and database searches were performed wit ...
... after five cycles of the enrichment protocol (see below) and selected by alpha complementation. From 101 plasmids, 11 cBEs were obtained, and of these, 4 had sequences related to cBE28. Both strands of the cBEs were dideoxy sequenced, and sequence comparisons and database searches were performed wit ...
Z66Ind gene detection and its relationship with the titer of antibodies
... invasiveness of Salmonella typhi, which can lead to perforation of the bowel (lymphoid tissue). In the process of bacterial invasion requires direct contact with the surface of host cells, attachment to the cell surface receptor and then enter the cell by endocytosis [6]. Flagella function thought t ...
... invasiveness of Salmonella typhi, which can lead to perforation of the bowel (lymphoid tissue). In the process of bacterial invasion requires direct contact with the surface of host cells, attachment to the cell surface receptor and then enter the cell by endocytosis [6]. Flagella function thought t ...
Impact of genetic engineering on the understanding of
... mouse strain expressing enhanced GFP (EGFP) under chicken beta-actin promoter showed that beta-actin is highly expressed in spermatogonia and elongating spermatids, and that its expression is regulated by FSH (Ventela et al., 2000). Finally, the generation of transgenic animals has been made by gene ...
... mouse strain expressing enhanced GFP (EGFP) under chicken beta-actin promoter showed that beta-actin is highly expressed in spermatogonia and elongating spermatids, and that its expression is regulated by FSH (Ventela et al., 2000). Finally, the generation of transgenic animals has been made by gene ...
Variations on a theme: Genomics of sex
... avian W; in contrast to this, sex chromosomes in fish, if present at all, are often homomorphic and differentiation is not detectable by karyotyping [2]. Overall, fish show frequent turnover of sex-determining systems [5], which stands in sharp contrast to other vertebrate clades, especially to bird ...
... avian W; in contrast to this, sex chromosomes in fish, if present at all, are often homomorphic and differentiation is not detectable by karyotyping [2]. Overall, fish show frequent turnover of sex-determining systems [5], which stands in sharp contrast to other vertebrate clades, especially to bird ...
RNA Interference and Small Interfering RNAs
... siRNAs is indicated. RNAi in the injected animal or its offspring. This is possible by the introduction of transgenes composed ing at a considerable distance. In plants, grafting experiof inverted repeats which produce dsRNA hairpins after tranments[48, 49] as well as the localized introduction of t ...
... siRNAs is indicated. RNAi in the injected animal or its offspring. This is possible by the introduction of transgenes composed ing at a considerable distance. In plants, grafting experiof inverted repeats which produce dsRNA hairpins after tranments[48, 49] as well as the localized introduction of t ...
HiPer® Bacterial Conjugation Teaching Kit
... elements. The factors (plasmids) contain about 20-30 genes, most of which are associated with conjugation. These genes encode enzymes that replicate DNA during conjugation and structural proteins needed to synthesize special pili at the cell surface. Known as F pili or sex pili, these hairlike fibre ...
... elements. The factors (plasmids) contain about 20-30 genes, most of which are associated with conjugation. These genes encode enzymes that replicate DNA during conjugation and structural proteins needed to synthesize special pili at the cell surface. Known as F pili or sex pili, these hairlike fibre ...
Online supplement: references - Evidence
... 1.48, 95% CI 1.24, 1.76), and especially l-allele homozygotes (OR = 1.17, 95% CI 0.91, 1.51). Risk of depression when exposed to both SLEs and 5HTT s-allele was greater than multiplicative (and hence also greater than additive). Of 33 studies that have examined this relationship since then, 17 have ...
... 1.48, 95% CI 1.24, 1.76), and especially l-allele homozygotes (OR = 1.17, 95% CI 0.91, 1.51). Risk of depression when exposed to both SLEs and 5HTT s-allele was greater than multiplicative (and hence also greater than additive). Of 33 studies that have examined this relationship since then, 17 have ...
physical maps
... Males have twofold higher mutation rate than females. Human races have very few unique distinguishing genes. All living organisms evolve from a common ancestor. Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
... Males have twofold higher mutation rate than females. Human races have very few unique distinguishing genes. All living organisms evolve from a common ancestor. Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
Chapter 4: EXTENSIONS OF MENDELIAN INHERITANCE
... that obey two laws: the law of segregation and the law of independent assortment. Until now, we have mainly considered traits that are affected by a single gene that is found in two different alleles. In these cases, one allele is dominant over the other. This type of inheritance is sometimes called ...
... that obey two laws: the law of segregation and the law of independent assortment. Until now, we have mainly considered traits that are affected by a single gene that is found in two different alleles. In these cases, one allele is dominant over the other. This type of inheritance is sometimes called ...
Pain Genes?: Natural Variation and Transgenic Mutants
... second order spinal cord neurons to innocuous stimuli. Finally, there are conditions in which pain is maladaptive; in these conditions, pain can be considered a disease of the nervous system. For example, after nerve injury, there may be intense, spontaneous pains, and various stimuli can evoke abno ...
... second order spinal cord neurons to innocuous stimuli. Finally, there are conditions in which pain is maladaptive; in these conditions, pain can be considered a disease of the nervous system. For example, after nerve injury, there may be intense, spontaneous pains, and various stimuli can evoke abno ...
Dynamic changes of yak (Bos grunniens) gut microbiota during
... years old), there were smaller proportion changes (< 0.5%) of these diet-related metabolism processes between ...
... years old), there were smaller proportion changes (< 0.5%) of these diet-related metabolism processes between ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.