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DFL1, an auxin-responsive GH3 gene homologue, negatively
DFL1, an auxin-responsive GH3 gene homologue, negatively

... application (Hagen and Guilfoyle, 1985; Roux and PerrotRechenmann, 1997). This G. max GH3 gene contains an auxin-responsive element in its promoter (Liu et al., 1994). Extensive studies have been made using this promoter to identify other auxin-responsive elements (Liu et al., 1994; Ulmasov et al., ...
PDF manual - QIAGEN Bioinformatics
PDF manual - QIAGEN Bioinformatics

... length fraction" and "Minimum similarity fraction" settings will be used only for the mapping of all entries in sequence lists where one or more of the reads is 56bp or longer. The mapping parameters are: • Maximum number of mismatches. This parameter is available if you have selected at least one s ...
White Paper: DMET™ Plus allele translation
White Paper: DMET™ Plus allele translation

... verification and validation. The haplotype names and definitions in the translation table adhere as closely as possible to the literature definitions of the haplotypes. To confirm accuracy of the information in the DMET Plus translation library file, an independent DMET Scientific Advisory Consortiu ...
Autism-lessons from the X chromosome
Autism-lessons from the X chromosome

... Such anomalies may occur during the formation of the gamete, during the formation of the zygote or after cell division begins in early embryonic development. In the former situation, the abnormality is going to be represented in every somatic cell. If the structural problem occurs later, in a segmen ...
Functional Analysis of Genes Implicated in Down Syndrome: 2
Functional Analysis of Genes Implicated in Down Syndrome: 2

... The association between atypical laterality and mental retardation has been reported several times, particularly in Down syndrome (DS). We investigated common genetic correlates of these components of the syndrome, examining direction (number of right paw entries in the Collins test) and degree (abs ...
123 Author`s personal copy
123 Author`s personal copy

... method consists in performing breeding (hybridization) experiments on different strains of the same species, and in observing the distribution of characters among individuals of different generations, in order to draw information concerning the transmission of genes, which are supposed to be respons ...
Sno/Ski Proto-Oncogene Family - The Newfeld Lab
Sno/Ski Proto-Oncogene Family - The Newfeld Lab

... Sno Function in Loss-of-Function Experiments Phenotypes generated when gene function is lost, for example, by mutation, engineered knockout at the DNA level or when transcripts are knocked down with a silencing RNA are impor­ tant clues to that gene’s function. The first Sno knockout mouse developed ...
Genomic Analysis of Hox Clusters in the Sea Lamprey
Genomic Analysis of Hox Clusters in the Sea Lamprey

... were aligned with those from mouse and amphioxus. This alignment was then used in a neighbor-joining analysis resulting in the bootstrapped tree of Figure 3. The known mouse Hox gene cognates cluster together on the neighbor-joining tree in all cases. Note that for the posterior (i.e., 5′) cognate g ...
genes is conserved among species related to
genes is conserved among species related to

... possesses two S-protein-encoding genes, one of which is silent, on a chromosomal segment of 6 kb. The 5-protein-encoding gene in the expression site can be exchanged for the silent S-protein-encoding gene by inversion of t h i s slp segment. In this study the presence of S-protein and corresponding ...
123 Author`s personal copy
123 Author`s personal copy

... method consists in performing breeding (hybridization) experiments on different strains of the same species, and in observing the distribution of characters among individuals of different generations, in order to draw information concerning the transmission of genes, which are supposed to be respons ...
Winge`s sex-linked color patterns and SDL in the guppy: genes or
Winge`s sex-linked color patterns and SDL in the guppy: genes or

... for human gene nomenclature" gives the following definition based on phenotypic point of view: "… a DNA segment that contributes to phenotype/function. In the absence of demonstrated function a gene may be characterized by sequence, transcription or homology". Gene Sweepstake Web Site - Sanger Insti ...
PDF
PDF

... complete eukaryotic genome (Nozaki et al., 2007). Interestingly, the genome shows extremely simplified structure that contains almost exclusively intron-lacking genes (only 26 genes contain an intron), very low percentage (0,7%) of transposable elements and a novel class of a repetitive element, cor ...
Ethylene 2013
Ethylene 2013

... based on this phenotype 3. Clone the corresponding gene by map-based cloning ...
The PTPN22 R620W mutation is independent of HLA
The PTPN22 R620W mutation is independent of HLA

... powered to detect associations after stratification by disease or serological subgroups. This may also explain why no significant associations were observed for the other SNPs with a low MAF. The SNPs tested were haplotype tagging SNPs which means that the true causal SNP may not have been tested di ...
Document
Document

... Analysis Map shows each transformation for easy adjustment of entire analysis protocol Powerful graphing and clustering tools provide comprehensive data analysis Expression profile searching and matching is easy and reproducible with user-generated gene lists Easy data and graph exporting feature pr ...
AACL BIOFLUX
AACL BIOFLUX

... for human gene nomenclature" gives the following definition based on phenotypic point of view: "… a DNA segment that contributes to phenotype/function. In the absence of demonstrated function a gene may be characterized by sequence, transcription or homology". Gene Sweepstake Web Site - Sanger Insti ...
Chapter 12 The Chromosomal Basis of Inheritance
Chapter 12 The Chromosomal Basis of Inheritance

... Behavior of a Chromosome Pair • In one experiment, Morgan mated male flies with white eyes (mutant) with female flies with red eyes (wild type) – The F1 generation all had red eyes – The F2 generation showed the 3:1 red:white ...
Solid Tumour Section tumors Atlas of Genetics and Cytogenetics
Solid Tumour Section tumors Atlas of Genetics and Cytogenetics

iTagPlot: an accurate computation and interactive drawing tool for
iTagPlot: an accurate computation and interactive drawing tool for

... Results: We have developed iTagPlot to compute tag density across functional features in parallel using multicores and a grid engine and to interactively explore it in a graphical user interface. It allows us to stratify features by defining groups based on biological function and measurement, summa ...
Parallels between UNUSUAL FLORAL ORGANS and FIMBRIATA
Parallels between UNUSUAL FLORAL ORGANS and FIMBRIATA

... Coen and Meyerowitz, 1991; Coen and Carpenter, 1993; Weigel and Meyerowitz, 1994). Meristem identity genes act early to switch on the floral genetic program, and their activity is required for the later expression of floral organ identity genes in specific domains of the meristem. Severa1 meristem a ...
A catalogue of imprinted genes and parent-of
A catalogue of imprinted genes and parent-of

... strongest evidence is provided by direct detection of parent-of-origin-specific transcription from a gene, for example as seen with SNRPN which is only transcribed from the paternally inherited allele. Detection of imprinted gene expression in some tissues does not necessarily indicate that the gene ...
The Drosophila Tissue Polarity Gene inturned Functions Prior to
The Drosophila Tissue Polarity Gene inturned Functions Prior to

(a) (b)
(a) (b)

... Behavior of a Chromosome Pair • In one experiment, Morgan mated male flies with white eyes (mutant) with female flies with red eyes (wild type) – The F1 generation all had red eyes – The F2 generation showed the 3:1 red:white ...
Chapter 2: Mendelian Inheritance
Chapter 2: Mendelian Inheritance

S-B-9-1_Rabbit Natural Selection Laboratory Activity
S-B-9-1_Rabbit Natural Selection Laboratory Activity

... 5. Shake the bag to simulate the rabbits mating. Without looking, select two alleles at a time. Place the rabbits (pairs of alleles) in the appropriate dish: FF, Ff, or ff. Record the results in the data table next to “Generation 1.” For example, if you draw colors represented by Ff, place a tally m ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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