Using bacterial biosensors to understand the genetic basis for
... • Successful construction of a light emitting biosensor library using an industrially isolated strain of Pseudomonas aeruginosa. • Screening using sub-MIC preservatives identified biosensors with altered light expression in both planktonic and agar growth. ...
... • Successful construction of a light emitting biosensor library using an industrially isolated strain of Pseudomonas aeruginosa. • Screening using sub-MIC preservatives identified biosensors with altered light expression in both planktonic and agar growth. ...
Pseudogenes as regulators of biological function
... results using such techniques suggest that as many as one-fifth of pseudogenes may be transcribed into RNA [5]. Recent RNA-seq experiments have shown that pseudogene RNA represents a significant proportion of the transcriptome in cancer cells [19]. A recent genome-wide study of pseudogene sequences ...
... results using such techniques suggest that as many as one-fifth of pseudogenes may be transcribed into RNA [5]. Recent RNA-seq experiments have shown that pseudogene RNA represents a significant proportion of the transcriptome in cancer cells [19]. A recent genome-wide study of pseudogene sequences ...
miRNA FAQs
... particular cell line. Inhibitors generally last longer than 48 hours in cells. The inhibitors are stabilized by their chemical modification pattern and have performed well in-house to at least 96 hours after transfection. We would suggest a time-course experiment to determine, empirically, how long ...
... particular cell line. Inhibitors generally last longer than 48 hours in cells. The inhibitors are stabilized by their chemical modification pattern and have performed well in-house to at least 96 hours after transfection. We would suggest a time-course experiment to determine, empirically, how long ...
ppt
... So, as something gets larger, the volume increases more than the surface area… and the demand for nutrients (to meet peak productivity) grows faster than the rate at which the more slowly increasing SA can supply them. So, supply fails to meet demand, and the cell cannot meet peak productivity… it b ...
... So, as something gets larger, the volume increases more than the surface area… and the demand for nutrients (to meet peak productivity) grows faster than the rate at which the more slowly increasing SA can supply them. So, supply fails to meet demand, and the cell cannot meet peak productivity… it b ...
A novel frameshift mutation of HEXA gene in the
... frameshift which are located throughout the gene, whereas most of the missense mutations are clustered in highly conserved amino acids in ligand-like binding domain. As in our patient who is the first case of genetically confirmed HEXA mutation in Thailand, the missense mutation is located in exon 1 ...
... frameshift which are located throughout the gene, whereas most of the missense mutations are clustered in highly conserved amino acids in ligand-like binding domain. As in our patient who is the first case of genetically confirmed HEXA mutation in Thailand, the missense mutation is located in exon 1 ...
The Genetic Architecture of Domestication in Animals
... further comb phenotype – the walnut comb). Other monogenic domestication traits have also been identified in the chicken – principally yellow skin color (controlled by the BCDO2 gene), 28 duplex comb, 29 and barred coat color genes.30 Dogs. In dogs, strong breed differences and extreme inbreeding ha ...
... further comb phenotype – the walnut comb). Other monogenic domestication traits have also been identified in the chicken – principally yellow skin color (controlled by the BCDO2 gene), 28 duplex comb, 29 and barred coat color genes.30 Dogs. In dogs, strong breed differences and extreme inbreeding ha ...
1b. Mendalian Genetics Definitions
... Genotypes of BB and Bb will result in the dominant trait in the offspring If an individual receives the allele for blue eyes from his/her mother and the allele for brown eyes from his/her father and blue eyes is the recessive trait, he/she will have brown eyes. ...
... Genotypes of BB and Bb will result in the dominant trait in the offspring If an individual receives the allele for blue eyes from his/her mother and the allele for brown eyes from his/her father and blue eyes is the recessive trait, he/she will have brown eyes. ...
Case Study: Visualization of annotated DNA sequences
... semantic zooming and annotation comparison, but zooming and panning is not real-time (VIII) and the browser does not support DNA sequence comparisons (X). Therefore, we have developed a DNA visualization tool that fulfills all defined requirements. DNAVis is written in C++ and runs on both Windows a ...
... semantic zooming and annotation comparison, but zooming and panning is not real-time (VIII) and the browser does not support DNA sequence comparisons (X). Therefore, we have developed a DNA visualization tool that fulfills all defined requirements. DNAVis is written in C++ and runs on both Windows a ...
Alteration of Iris Color (Melanin Production) is Achieved via
... We chose to alter eye color in humans for aesthetic purposes. Certain SNPs have high associations with different eye colors. We plan on altering the already existing SNPs in the OCA2 and HERC2 genes in order to create the desired color. (Tori) The version of the HERC2 gene that a person carries i ...
... We chose to alter eye color in humans for aesthetic purposes. Certain SNPs have high associations with different eye colors. We plan on altering the already existing SNPs in the OCA2 and HERC2 genes in order to create the desired color. (Tori) The version of the HERC2 gene that a person carries i ...
An early dihybrid cross
... shown for the B-C distance. Of course, these two possibilities can be discriminated by examining the actual recombination frequency between B and C. Genetica per Scienze Naturali a.a. 08-09 prof S. Presciuttini ...
... shown for the B-C distance. Of course, these two possibilities can be discriminated by examining the actual recombination frequency between B and C. Genetica per Scienze Naturali a.a. 08-09 prof S. Presciuttini ...
Mutations in a gene encoding a novel protein tyrosine
... isoforms predicted to have different functions, in a manner analogous to the Drosophila PTP, dPTP61F, which also undergoes alternative splicing at the 3´ end17. In the case of dPTP61F, it is known that the alternate C termini govern the localization of the protein to either the cytoplasmic membrane ...
... isoforms predicted to have different functions, in a manner analogous to the Drosophila PTP, dPTP61F, which also undergoes alternative splicing at the 3´ end17. In the case of dPTP61F, it is known that the alternate C termini govern the localization of the protein to either the cytoplasmic membrane ...
Gene Regulation Notes
... • General transcription factors are essential for the transcription of all protein-coding genes ...
... • General transcription factors are essential for the transcription of all protein-coding genes ...
Sample pages 2 PDF
... short enough for GWAS to even isolate a single candidate gene for an association. Also, GWAS works on unrelated individuals, so natural populations can be investigated without the need to construct a pedigree. However, a GWAS is a major undertaking in terms of both sample size and construction of ma ...
... short enough for GWAS to even isolate a single candidate gene for an association. Also, GWAS works on unrelated individuals, so natural populations can be investigated without the need to construct a pedigree. However, a GWAS is a major undertaking in terms of both sample size and construction of ma ...
Limitations of Pseudogenes in Identifying Gene Losses
... while the other 91 do not. We were also able to identify a large number of previously unannotated genes in the D. melanogaster genome, most of which also had evidence for transcription. Though our results suggest that pseudogene-based methods for finding gene losses will miss a large proportion of th ...
... while the other 91 do not. We were also able to identify a large number of previously unannotated genes in the D. melanogaster genome, most of which also had evidence for transcription. Though our results suggest that pseudogene-based methods for finding gene losses will miss a large proportion of th ...
On the origin and frequency of Y chromosome deletions responsible
... Identifying the site of origin of deletions is reminiscent of similar classical studies on varying rates of sensitivity to mutagenesis in successive spermatogenic and spermiogenic stages in mammals. Sensitivity was originally measured by relating the degree of induced mutation to different spermatog ...
... Identifying the site of origin of deletions is reminiscent of similar classical studies on varying rates of sensitivity to mutagenesis in successive spermatogenic and spermiogenic stages in mammals. Sensitivity was originally measured by relating the degree of induced mutation to different spermatog ...
Binding of ColEl-kan Plasmid DNA by Tobacco
... the screening procedure employed required that the kanamycin resistance gene be maintained within the plant cell for many generations. Maintenance via autonomous replication of the plasmid would require that the plasmid be taken up physically intact by the protoplasts. This may not have occurred. Th ...
... the screening procedure employed required that the kanamycin resistance gene be maintained within the plant cell for many generations. Maintenance via autonomous replication of the plasmid would require that the plasmid be taken up physically intact by the protoplasts. This may not have occurred. Th ...
Genes for Cognitive Function: Developments on the X
... nih.gov/Omim/). In ∼75% of these, MR is a component of a syndromal autosomal recessive or dominant phenotype. There is no known autosomal form of familial nonspecific MR similar to MRX. A recent update on XLMR (Lubs et al. 1999) reviewed 178 XLMR entries of which 120 are syndromal (MRXS) and 58 are ...
... nih.gov/Omim/). In ∼75% of these, MR is a component of a syndromal autosomal recessive or dominant phenotype. There is no known autosomal form of familial nonspecific MR similar to MRX. A recent update on XLMR (Lubs et al. 1999) reviewed 178 XLMR entries of which 120 are syndromal (MRXS) and 58 are ...
General background text Pharmacogenetics - CYP3A4
... in question and the combination with environmental factors such as co-medication, diet and disease conditions. Variations can exist in a population for the DNA that encodes for a protein. Variations can result in alleles that encode for proteins with no or reduced activity. The simplest form of vari ...
... in question and the combination with environmental factors such as co-medication, diet and disease conditions. Variations can exist in a population for the DNA that encodes for a protein. Variations can result in alleles that encode for proteins with no or reduced activity. The simplest form of vari ...
Chromosome Locations of the MYB Related Genes, AMYB and
... (3). Early studies had indicated a role for MYB in differentiation (3-5) and recent evidence suggests that the MYB gene product is required for cell proliferation (6, 7). Nomura et al. (8) have isolated and characterized cDNA3 clones for two human MYB related genes, AMYB and BMYB, and expression of ...
... (3). Early studies had indicated a role for MYB in differentiation (3-5) and recent evidence suggests that the MYB gene product is required for cell proliferation (6, 7). Nomura et al. (8) have isolated and characterized cDNA3 clones for two human MYB related genes, AMYB and BMYB, and expression of ...
DNA helicase deficiencies associated with cancer
... death (1,2). Moreover, the loss of p53 results in genomic instability. In WS cells, p53-mediated apoptosis is attenuated, while ectopic expression of WRN in these cells can rescue this deficiency (29). Overexpression of WRN results in elevated p53dependent transcriptional activity and induction of p ...
... death (1,2). Moreover, the loss of p53 results in genomic instability. In WS cells, p53-mediated apoptosis is attenuated, while ectopic expression of WRN in these cells can rescue this deficiency (29). Overexpression of WRN results in elevated p53dependent transcriptional activity and induction of p ...
Genetics: the Breeder`s Blueprint
... trait or group of traits which tend to occur in the same manner. But what about traits which, as a group, behave in a recessive manner? Since recessives are masked by dominants, they can be difficult to isolate. (The recessive genes often control undesirable traits such as an undershot jaw or light ...
... trait or group of traits which tend to occur in the same manner. But what about traits which, as a group, behave in a recessive manner? Since recessives are masked by dominants, they can be difficult to isolate. (The recessive genes often control undesirable traits such as an undershot jaw or light ...
Virus on virus infects bacterium
... other. For example, not all strains of V. cholerae that express TCP can form transferable bacteriophage particles. Perhaps most of the TcpA is incorporated into a colonization pilus, and the remainder is used to coat the DNA in infectious phage particles (but only in those strains that can produce t ...
... other. For example, not all strains of V. cholerae that express TCP can form transferable bacteriophage particles. Perhaps most of the TcpA is incorporated into a colonization pilus, and the remainder is used to coat the DNA in infectious phage particles (but only in those strains that can produce t ...