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Effects of Inbreeding and Heterosis in Hereford Lines on
Effects of Inbreeding and Heterosis in Hereford Lines on

... This alternative mechanism is called epistasis. Previous research documents reduced performance resulting from the mating of closely related individuals (inbreeding). Inbreeding generally reduces growth and reproductive rates and delays maturity. This inbreeding depression arises from increasing the ...
The human genome. Implications for medicine and society
The human genome. Implications for medicine and society

... aid of such maps, on which genetic markers are indicate the region where the gene which interests us is located, the region containing the said gene can be isolated through cloned fragments that represent the particular region and are available. Due to the fact that mapping and definition of the nuc ...
CDKN2 (p16/MTS1) Gene Deletion or CDK4
CDKN2 (p16/MTS1) Gene Deletion or CDK4

... The distance between the CDKN2 gene and its flanking loci, MTS2 and 1063. 7 has been estimated to be between 20 and 30 kilobases (7). In this study, breakpoints have been demonstrated within this rela tively short distance in a number of the tumors. Breakpoints occurred between the MTS2 locus and th ...
The Homologous Drosophila Transcriptional Adaptors ADA2a and
The Homologous Drosophila Transcriptional Adaptors ADA2a and

... revealed by in vitro pull-down experiments (19). Dmp53 induces apoptosis in response to genotoxic stresses by transactivating proapoptotic target genes through specific response elements in their promoters. Interestingly, the response elements to which Dmp53 binds are similar or identical to those r ...
Familial Long QT Syndrome
Familial Long QT Syndrome

miRNA pptx - NUS School of Computing
miRNA pptx - NUS School of Computing

... Improving miRNA Target Genes Prediction Rikky Wenang Purbojati ...
Dominant and recessive central core disease associated with
Dominant and recessive central core disease associated with

... kyphoscoliosis), the two surviving children improved their motor milestones and had a normal intellectual development. The muscular weakness appeared to be `non-progressive'; there was no cardiac involvement and the respiratory capacities were acceptable for their respective ages. It should be noted ...
Emphysema - Harlem Children Society
Emphysema - Harlem Children Society

... Antioxidants and Lung • Rich network of antioxidants to protect the lung • Antioxidants are increased in response to cigarette smoke • Antioxidant responses are quite variable • Differences in antioxidant responses may account for differences in disease susceptibility • Epidemiologic data links ant ...
Zebrafish and Skin Color Reference Data
Zebrafish and Skin Color Reference Data

... SLC24A5 gene is larger than the region shown above. Recall that the golden phenotype in zebrafish is also caused by a change in the SLC24A5 gene, but it is the result of a different mutation. The mutation that causes the golden phenotype in zebrafish is located farther upstream of the amino acids ...
Mendelian Genetics
Mendelian Genetics

... Mendel’s work, plant and animal breeders based their work on the theory of “Blending”. ...
Adaptation to nocturnality - learning from avian genomes
Adaptation to nocturnality - learning from avian genomes

... additionally sequenced to reduce false positive results. The result of such analyses (comparative genomics and gene ontology analyses) is typically a list of processes or functions (for example metabolic pathways) that are significantly associated with, for example, nocturnality. For example, many c ...
genes. Numbers of 6-10 copies per genome have
genes. Numbers of 6-10 copies per genome have

... genes11,39,40. The position of the first intron is the same as that found for other small subunit genes11,39. Comparison of TSSU3-8 to NtSS23 shows a striking degree of homology. The sequences from the ATG to the EcoRl site, including the intron, are identical. This is unexpected as intron sequences ...
X-adrenoleukodystrophy
X-adrenoleukodystrophy

... The lifetime of a mouse in the lab can be up to about two and a half years. In previous studies, it was found that mice do not develop any pathological symptoms until at least the age of 6 months (Pujol et al., 2002). In light of these facts, any experiments conducted on the lab mice should be done ...
Full Paper - Biotechniques.org
Full Paper - Biotechniques.org

... 2007), 18S rRNA (Zimmerman et al. 2011), and rbcL (Paul et al. 2000). The rbcL gene is of particular interest because it codes for the large subunit of the protein ribulose-1,5-bisphosphate carboxylase oxygenase (RuBisCO). RuBisCO is a key enzyme in the carbon fixation step of the Calvin Cycle. Ther ...
Dutch Elm Disease (DED) Ophiostoma ulmi and Ophiostoma ulmi
Dutch Elm Disease (DED) Ophiostoma ulmi and Ophiostoma ulmi

Paradox of Animal Sociality,
Paradox of Animal Sociality,

... 50-50 chance of having both received that gene from your parents. The analysis that produces this conclusion is called "path analysis". It starts with designating a particular relative, A, and traces all the paths by which the same gene might have been passed to relative, B. Two individuals are rela ...
No Slide Title
No Slide Title

... gene of interest – good to create mouse models for human diseases • knockout the same gene disrupted in a human and may be able to understand disease better and develop efficacious treatments • excellent review is Müller (1999) Mechanisms of Development 82, 321. ...
Integrating Genetic and Network Analysis to Characterize Genes
Integrating Genetic and Network Analysis to Characterize Genes

... The relationship between connectivity and knock-out essentiality is dependent on the module under consideration. Hub genes in some modules may be non-essential. This study shows that intramodular connectivity is much more meaningful than whole network connectivity: ...
Growth hormone genotyping by MspI restriction enzyme and PCR
Growth hormone genotyping by MspI restriction enzyme and PCR

... increasing and is able to reduce Indonesian dependency on beef and cattle from other countries. The GH gene is a single peptide of molecular weight equal to 22-kD secreted from pituitary gland in circadian and pulsatile manner, the pattern of which plays important role in postnatal longitudinal grow ...
U05_Heredity_Study_Guide_T
U05_Heredity_Study_Guide_T

... CONTENT GUIDE (This includes the major concepts for which students will be responsible in this unit. Additional content as studied in the unit under these major concepts may be included. Examples would include information from labs, activities, diagrams, tables and charts. The student must also be a ...
Validating therapeutic targets through human genetics
Validating therapeutic targets through human genetics

... in a Nobel Prize7. Hench observed that the symptoms of patients with rheumatoid arthritis improved during pregnancy and following temporary stress brought upon by surgery — both clinical conditions in which levels of endogenous steroid hormones were known to be elevated. Hench was also aware of the ...
Genes
Genes

... • Transcend phenomenological diagnosis, and represent mechanisms of disease • Offer the potential to identify at-risk individuals and biological pathways for the development of ...
asSeq: A set of tools for the study of allele-specific RNA
asSeq: A set of tools for the study of allele-specific RNA

... can easily collapse these counts at exon set level into gene level. If some exons are shared by two genes, we will treat those exons shared by two genes as a gene. Allele-specific expression has been extracted into two BAM files in the previous step and they can be counted the same way. ...
Depth-stratified functional and taxonomic niche
Depth-stratified functional and taxonomic niche

... evolve under different selective pressures than their host versions and have recombined back into the host (Sullivan et al., 2006). Cyanophage AMGs can also evolve to the point that they perform modified function. For example, when discovered, viral pebS was most similar to a cyanobacterial pebA gen ...
Practice with Monohybrid Punnett Squares
Practice with Monohybrid Punnett Squares

... Often times, people will refer to a trait or characteristic such as eye color or hair color as being genetic, but what does the word genetic really mean? Genetics is termed as the study of heredity and how traits in offspring are based upon those of the parents. Heredity is the process in which trai ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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