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Base Composition and Translational Selection are Insufficient to
Base Composition and Translational Selection are Insufficient to

... 5.7kb that is translated from subgenomic RNAs, and geminiviruses have one or two circular, ~2.7kb, ambisense genomic segments that are transcribed by host enzymes [23]. Unlike cellular organisms, which share related genes across extremely divergent clades, which can be used as the basis for phylogen ...
Functional SNPs in the SCGB3A2 promoter are
Functional SNPs in the SCGB3A2 promoter are

... of susceptibility genes (3) and non-genetic factors, such as infection (4). Many genetic studies of GD have been carried out and several genes, such as human leukocyte antigen (3), cytotoxic T lymphocyte antigen 4 (CTLA-4) (5,6), CD40 gene (7), PTPN22 (8), TSHR (9) and SAS-ZFAT (10) have been linked ...
Advances in Environmental Biology  Zahra Maryami, Arash Fazeli, Ali-Ashraf Mehrabi
Advances in Environmental Biology Zahra Maryami, Arash Fazeli, Ali-Ashraf Mehrabi

... (GBSSI) is one of the most important determinants of starch synthesis of cereals [7] which are located on the group-7 chromosomes of each genomes [8,9]. In bread wheat (TriticumaestivumL. ssp. aestivum; 2n = 6x = 42, AABBDD), three waxy proteins, one for each genome, have been identified. Each waxy ...
Regulation and Flexibility of Genomic Imprinting
Regulation and Flexibility of Genomic Imprinting

... ranging from the regulation of pigmentation, protein storage, transcriptional regulation, chromatin modification, and cytoskeletal function to mRNA regulation (Table 1). For instance, five recently described potentially imprinted genes, for which only transcripts from one parental allele were detect ...
Finding Patterns in Protein Sequence and Structure
Finding Patterns in Protein Sequence and Structure

... • There are about 3bn (3  109) nucleotides in the nucleus of almost all of the trillions (3.5  1012 ) of cells of a human body (an exception is, for example, red blood cells which have no nucleus and therefore no DNA) – a total of ~1022 nucleotides! • Many DNA regions code for proteins, and are ca ...
Screening of a Specific Point Mutation in Tumor Suppressor p53
Screening of a Specific Point Mutation in Tumor Suppressor p53

... The point mutation at a specific site (the third base of codon 249 of exon 7) in the p53 gene was not found in the 8 hepatocellular carcinoma samples from Korean patients. This result is quite different from the report on Chinese and South African patients that showed the point mutations at the same ...
Epigenetic memory in mammals
Epigenetic memory in mammals

... Epigenetic information is encrypted in genetic sequences, and includes DNA methylation, histone modifications and small RNA changes (Bonasio et al., 2010). Epigenetic memory is the ability to transfer epigenetic information from one generation to the next. Epigenetic information uses patterns of inhe ...
Population genetics and the modern synthesis of evolutionary theory
Population genetics and the modern synthesis of evolutionary theory

... − or in terms of alleles: “70% of the thumb alleles are S, and 30% are h” − we can think of a population as a gene pool: − the collection of alleles, lurking in individuals, from which alleles are randomly drawn to create gametes, which in turn randomly combine in sexual reproduction to form the nex ...
Solving Even-Parity Problems using Multi Expression Programming
Solving Even-Parity Problems using Multi Expression Programming

... and even-4 parity problems using a population of 4000 individuals [3]. The cumulative probability of success was 100% for the even-3-parity problem and 42% for the even-4-parity problem [3]. A perfect comparison between MEP and GP cannot be made due to the incompatibility of the respective represent ...
Chapter 6 GENETIC LINKAGE AND MAPPING IN EUKARYOTES
Chapter 6 GENETIC LINKAGE AND MAPPING IN EUKARYOTES

... the same chromosome, the linkage can be altered during meiosis. In diploid eukaryotic species, homologous chromosomes can exchange pieces with each other, a phenomenon called crossing over. This event occurs during prophase of meiosis I. As discussed in Chapter 3, the replicated chromosomes, known a ...
Discovery of Paralogous Nuclear Gene Sequences Coding for the
Discovery of Paralogous Nuclear Gene Sequences Coding for the

... within a three-dimensional framework is mainly determined by the structure and mutual interactions of the two largest subunits (Wlassoff, Kimura, and Ishihama 1999). Under the assumption that RPB2 is generally single-copy, it has been suggested that it has great potential for phylogenetic studies (S ...
Not now, but soon: Justification for continued research on CRISPR
Not now, but soon: Justification for continued research on CRISPR

... in the germline cells of embryos that will be inherited by future generations. While somatic cell therapies alter non-reproductive cells and thus affect only the one patient, germline therapy in contrast can affect the DNA of the patient’s children, grandchildren and even great grandchildren. Creati ...
Amplification and partial sequencing of Ixodes Scapularis Shaker
Amplification and partial sequencing of Ixodes Scapularis Shaker

... passing pathogens to humans that cause lyme disease, rocky mountain spotted fever and tularemia (9). The research project undertaken provides an easy and efficient means to begin the tick DNA sequencing on a small scale, which can be done in almost any molecular biology laboratory. The sequence homo ...
HMW glutenin subunits in multiploid Aegilops species: composition
HMW glutenin subunits in multiploid Aegilops species: composition

... amino acid sequence similarity to the 1Dy subunits specified by the Glu-1D locus[9 11]. In contrast to the studies carried for Ae. tauschii, little is known about the composition of HMW glutenin subunits and the genes encoding these polypeptides in polyploid Aegilops species (such as Ae. crassa, Ae. ...
Genetic background of systemic sclerosis: autoimmune genes take
Genetic background of systemic sclerosis: autoimmune genes take

... Complex genetic diseases are influenced by the interplay of multiple genes and/or the environment; susceptibility genes act in concert to increase an individual’s risk of disease. Thus, in contrast to the situation in monogenic traits, most susceptibility genes exert only a minor individual effect o ...
Color and Scent: How Single Genes Influence Pollinator Attraction
Color and Scent: How Single Genes Influence Pollinator Attraction

... genes. AN2, AN1, and AN11 code for a R2R3-MYB transcription factor (R2R3-MYB), a basic-helix-loop-helix (bHLH) transcription factor, and a WD40-repeat (WDR) protein, respectively. These proteins act in a complex (MYB-bHLH-WDR) to coordinately up-regulate the expression of late anthocyanin biosynthet ...
Case Study #5 - davis.k12.ut.us
Case Study #5 - davis.k12.ut.us

... 2. The symptoms of Hemophilia include excessive bleeding. This bleeding may occur externally due to injury but more often occurs spontaneously as bleeding into the joints. Symptoms are often first evident during circumcision. In this case, the infant had not been circumcised. Symptoms did not become ...
The Primary Structure of a 4.0-kDa Photosystem I Polypeptide
The Primary Structure of a 4.0-kDa Photosystem I Polypeptide

... but complete amino acidsequences corresponding to five formic acid at 40 “C. Plasma Desorption Mass Spectrometry-For molecular mass deterdifferent nuclear-encodedsubunits have beenreported (4-10). mination, the lyophilized polypeptide was dissolved in 0.1% trifluoThe amino acid sequence of the three ...
DNA Denaturing through UV-C Photon Dissipation: A
DNA Denaturing through UV-C Photon Dissipation: A

... as a result of UV-C light induced denaturing by photon dissipation, the extinction rises during the light on periods, due to absorption hyperchromicity and increased Rayleigh or Mie scattering of the denatured strands . Figure 2(b) shows the correlation spectrum of the extinction peaks versus only s ...
(EC 2.2.1.1) active in the Calvin cycle of spinach chloroplasts
(EC 2.2.1.1) active in the Calvin cycle of spinach chloroplasts

... per lane. The film was exposed for 48 h at -80 °C. ...
Involvement of HLS1 in Sugar and Auxin
Involvement of HLS1 in Sugar and Auxin

... affecting a common part of the signaling pathways for both sugar-induced and sugar-repressed gene expression. HLS1 expression in vegetative and reproductive tissues was much lower (20-fold less) than that in etiolated seedlings in the dark (Lehman et al. 1996). hls1-1 and hls1-7 genes have base subs ...
1. The evolutionary process that favors individuals of a species that
1. The evolutionary process that favors individuals of a species that

... A. surrogate mothering B. gamete intrafallopian transfer C. artificial insemination D. in vitro fertilization 59. Norah and Bob are elated as they have just brought their twins home. After trying to have a baby of their own for eight years, they opted for fertility treatment a year ago. Their gamete ...
Natural Selection Lab
Natural Selection Lab

... Part D – Heterozygous Advantage – Simulating the Sickle Cell Condition 1. Place 10 Blue beads and 10 Red beads into your “population” container. Assume that Blue beads represent the dominant allele (normal hemoglobin – T) and Red represents the recessive allele (sickle cell hemoglobin – t). Mix the ...
Genetic identification of eleven aquatic bacteria using the 16S rDNA
Genetic identification of eleven aquatic bacteria using the 16S rDNA

... The identification of bacteria is fundamental to understanding the biodiversity in an ecosystem as well as the ecological processes. Bacteria are very important to the environment because they interact with life on Earth by their metabolic activities. Nitrifying bacteria, for instance, make nitrogen ...
Powerpoint Presentation: Meiosis
Powerpoint Presentation: Meiosis

... © 2010 Paul Billiet ODWS ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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