Variable Autosomal and X Divergence Near and Far from Genes
... This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For ...
... This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For ...
Molecular Characterization of CDC42, a Saccharomyces cerevisiae
... (R) and HinfI (Hf) sites are also shown. YEp(42)3 was constructed by inserting the l.l-kb Hpa I-Xba I fragment from pBR(42)l into Sma I/Nhe I-digested YEp24. YEp(42)4 was constructed by inserting the ,,o0.5-kb Rsa I fragment from pBR(42)3 into Pvu II-digested YEp24. YEp(42)5 was constructed by inser ...
... (R) and HinfI (Hf) sites are also shown. YEp(42)3 was constructed by inserting the l.l-kb Hpa I-Xba I fragment from pBR(42)l into Sma I/Nhe I-digested YEp24. YEp(42)4 was constructed by inserting the ,,o0.5-kb Rsa I fragment from pBR(42)3 into Pvu II-digested YEp24. YEp(42)5 was constructed by inser ...
Identification of novel endogenous antisense transcripts by DNA
... either poly(A)+ or total RNA (data not shown), but quantitative RT-PCR, ISH and microarray analyses were able to detect this transcript within the testis and kidney (see Additional file 5). This result implies that NATs detected by microarray analysis using AFAS probes are transcribed in vivo. We al ...
... either poly(A)+ or total RNA (data not shown), but quantitative RT-PCR, ISH and microarray analyses were able to detect this transcript within the testis and kidney (see Additional file 5). This result implies that NATs detected by microarray analysis using AFAS probes are transcribed in vivo. We al ...
PTC_241Lecture005Cells
... have to bind transcription factors in order for transcription to take place. So protein synthesis just doesn’t happen willy nilly. It’s only activated when certain kind of factors bind to the chromosome and start transcription. So it’s a switch that turns transcription on, turns transcription off. S ...
... have to bind transcription factors in order for transcription to take place. So protein synthesis just doesn’t happen willy nilly. It’s only activated when certain kind of factors bind to the chromosome and start transcription. So it’s a switch that turns transcription on, turns transcription off. S ...
F 1 Generation
... Overview: Locating Genes Along Chromosomes • Mendel’s “hereditary factors” were genes, though this wasn’t known at the time • Today we can show that genes are located on chromosomes • The location of a particular gene can be seen by tagging isolated chromosomes with a fluorescent dye that highlights ...
... Overview: Locating Genes Along Chromosomes • Mendel’s “hereditary factors” were genes, though this wasn’t known at the time • Today we can show that genes are located on chromosomes • The location of a particular gene can be seen by tagging isolated chromosomes with a fluorescent dye that highlights ...
Inheritance (heredity): The transmission of genes from parents to
... The transmission of genes from parents to offspring. * Gene: - Unit of information about heritable trait passed from parents to offspring. - Each gene has a specific location (locus) on a chromosome. * Alleles: - Alternate forms of genes. - Designated by letters. * Dominant = Capital E, A, S, T, …. ...
... The transmission of genes from parents to offspring. * Gene: - Unit of information about heritable trait passed from parents to offspring. - Each gene has a specific location (locus) on a chromosome. * Alleles: - Alternate forms of genes. - Designated by letters. * Dominant = Capital E, A, S, T, …. ...
Multimeric Protein Structures of African Horsesickness Virus
... aetiological agent of African horsesickness, a highly infectious non-contagious disease of equines. The AHSV virion is composed of seven structural proteins organised into a double layered capsid, which encloses ten double-stranded RNA segments. The double stranded (ds) RNA genome of AHSV encodes, i ...
... aetiological agent of African horsesickness, a highly infectious non-contagious disease of equines. The AHSV virion is composed of seven structural proteins organised into a double layered capsid, which encloses ten double-stranded RNA segments. The double stranded (ds) RNA genome of AHSV encodes, i ...
Sterile, 24-well tissue culture plates are filled with melted minimal ... 1.0 ml per well using a repeating syringe. After the...
... The plates are incubated seven days at 25°C in a plastic bag to prevent drying. Pairings giving wild type growth are repeated on minimal agar plates (C orrell et al. 1987) to confirm the complementation reaction. Complementation reactions are more definitive when the auxotrophic mutants are separate ...
... The plates are incubated seven days at 25°C in a plastic bag to prevent drying. Pairings giving wild type growth are repeated on minimal agar plates (C orrell et al. 1987) to confirm the complementation reaction. Complementation reactions are more definitive when the auxotrophic mutants are separate ...
Molecular Genetics and Genomics
... site, is located on the 3.7-kb PstI fragment. R. leguminosarum bv trifolii RS800 harbors three plasmids with molecular weights of about 190, 280, and 470 MDa (Rodriguez-QuinÄones et al. 1989). In order to locate the exoB gene in the genome of RS800, a blotted Eckhardt gel (Rosenberg et al. 1982) was ...
... site, is located on the 3.7-kb PstI fragment. R. leguminosarum bv trifolii RS800 harbors three plasmids with molecular weights of about 190, 280, and 470 MDa (Rodriguez-QuinÄones et al. 1989). In order to locate the exoB gene in the genome of RS800, a blotted Eckhardt gel (Rosenberg et al. 1982) was ...
Leukaemia Section t(3;12)(q26;p13) ETV6/MECOM / t(3;12)(q26;p13) ETV6/EVI1 Atlas of Genetics and Cytogenetics
... The ETV6 gene spans a region of less than 250 kb at band 12p13.1 and consists of 8 exons. There are two start codons, one (exon 1a starting at codon 1) located at the beginning of the gene and another alternative (exon 1b starting at codon 43) upstream of exon 3. Protein The ETV6 protein (452 amino ...
... The ETV6 gene spans a region of less than 250 kb at band 12p13.1 and consists of 8 exons. There are two start codons, one (exon 1a starting at codon 1) located at the beginning of the gene and another alternative (exon 1b starting at codon 43) upstream of exon 3. Protein The ETV6 protein (452 amino ...
Ii.
... indicating that tandem amplification of this sequence is tolerated until a threshold number of copies is reached. ◦ iv.Amplification of CGG repeats occurs only in females, perhaps during a slipped mispairing process during DNA replication. ◦ v. The FMR-1 product (FMRP) is an RNA-binding protein. The ...
... indicating that tandem amplification of this sequence is tolerated until a threshold number of copies is reached. ◦ iv.Amplification of CGG repeats occurs only in females, perhaps during a slipped mispairing process during DNA replication. ◦ v. The FMR-1 product (FMRP) is an RNA-binding protein. The ...
Chromosome number 2
... indicating that tandem amplification of this sequence is tolerated until a threshold number of copies is reached. ◦ iv.Amplification of CGG repeats occurs only in females, perhaps during a slipped mispairing process during DNA replication. ◦ v. The FMR-1 product (FMRP) is an RNA-binding protein. The ...
... indicating that tandem amplification of this sequence is tolerated until a threshold number of copies is reached. ◦ iv.Amplification of CGG repeats occurs only in females, perhaps during a slipped mispairing process during DNA replication. ◦ v. The FMR-1 product (FMRP) is an RNA-binding protein. The ...
Population genetics
... genetics, descriptions can be made of the frequencies of various genotypes and alleles in populations, and/or the levels of genetic variation can be determined. A population is a collection of organisms of a single species the individuals of which interact with each other in some way. So, a species ...
... genetics, descriptions can be made of the frequencies of various genotypes and alleles in populations, and/or the levels of genetic variation can be determined. A population is a collection of organisms of a single species the individuals of which interact with each other in some way. So, a species ...
View/Open
... XY placentas being significantly larger than XX placentas and that such differences are independent of androgen effects [37]. Although the possession of one X chromosome rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattl ...
... XY placentas being significantly larger than XX placentas and that such differences are independent of androgen effects [37]. Although the possession of one X chromosome rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattl ...
Presentation
... A plot of # “lethal” aberrations vs natural log S.F. showed that an average of 1 lethal lesion decreased survival by e. In other words, S.F. = e –(D + bD2) ...
... A plot of # “lethal” aberrations vs natural log S.F. showed that an average of 1 lethal lesion decreased survival by e. In other words, S.F. = e –(D + bD2) ...
Genes in conflict: the biology of selfish genetic elements
... the process is thought to have gone to completion: there are no mitochondria, but there are other organelles called hydrogenosomes that appear to be derived from mitochondria but do not contain any DNA at all (Embley et al. 2003). In all species, the vast majority of proteins in mitochondria are enc ...
... the process is thought to have gone to completion: there are no mitochondria, but there are other organelles called hydrogenosomes that appear to be derived from mitochondria but do not contain any DNA at all (Embley et al. 2003). In all species, the vast majority of proteins in mitochondria are enc ...
how to analyze a splicing mutation - Stamm revision
... point mutations [1]. Furthermore, for some genes this is much higher for example in NF1 and ATM, it has been shown that mutations that cause splicing alterations occur in approximately 50% of the affected patients [2,3]. Of these mutations, 24% would have been mis-assessed as frameshift, missense or ...
... point mutations [1]. Furthermore, for some genes this is much higher for example in NF1 and ATM, it has been shown that mutations that cause splicing alterations occur in approximately 50% of the affected patients [2,3]. Of these mutations, 24% would have been mis-assessed as frameshift, missense or ...
Glycosylphosphatidyl inositol-anchored protein (GPI
... expressed genes. We validated the differential expression of several of the genes identified through Biochip analysis, by means of quantitative RT-PCR of RNA from 48 thymoma tumors. We found that GPI-80 was significantly higher in invasive thymoma (stage IV thymoma) than in stage I thymoma. It has p ...
... expressed genes. We validated the differential expression of several of the genes identified through Biochip analysis, by means of quantitative RT-PCR of RNA from 48 thymoma tumors. We found that GPI-80 was significantly higher in invasive thymoma (stage IV thymoma) than in stage I thymoma. It has p ...
Functional SNPs in the SCGB3A2 promoter are
... of susceptibility genes (3) and non-genetic factors, such as infection (4). Many genetic studies of GD have been carried out and several genes, such as human leukocyte antigen (3), cytotoxic T lymphocyte antigen 4 (CTLA-4) (5,6), CD40 gene (7), PTPN22 (8), TSHR (9) and SAS-ZFAT (10) have been linked ...
... of susceptibility genes (3) and non-genetic factors, such as infection (4). Many genetic studies of GD have been carried out and several genes, such as human leukocyte antigen (3), cytotoxic T lymphocyte antigen 4 (CTLA-4) (5,6), CD40 gene (7), PTPN22 (8), TSHR (9) and SAS-ZFAT (10) have been linked ...
NDC1 : A Nuclear Periphery Component Required for Yeast Spindle Pole Body Duplication.
... SPBs stage (Winey et al., 1991). Two recently identified mutants, mpsl and mps2 (monopolar spindle), identify genes whose functions are essential for this transition (Winey et al., 1991). Upon transfer to the nonpermissive temperature, mpsl-1 strains fail in SPB duplication, yielding a single large ...
... SPBs stage (Winey et al., 1991). Two recently identified mutants, mpsl and mps2 (monopolar spindle), identify genes whose functions are essential for this transition (Winey et al., 1991). Upon transfer to the nonpermissive temperature, mpsl-1 strains fail in SPB duplication, yielding a single large ...
How does the cell regulate arsenate respiration and
... a. Expression represents the ratio of the relative quantity of arrA or arsC transcripts to that of the housekeeping gene gyrB. b. Induction was determined by normalizing the expression value for arrA or arsC to no As conditions. Saltikov et al. J. Bacteriology 2005. 187 (21): 7390-7396 ...
... a. Expression represents the ratio of the relative quantity of arrA or arsC transcripts to that of the housekeeping gene gyrB. b. Induction was determined by normalizing the expression value for arrA or arsC to no As conditions. Saltikov et al. J. Bacteriology 2005. 187 (21): 7390-7396 ...
Recombination
... a probability of 0.5 for both the formation of each gamete followed by random assortment: paternal gametes R r R RR Rr r ...
... a probability of 0.5 for both the formation of each gamete followed by random assortment: paternal gametes R r R RR Rr r ...
Untitled
... understand the mechanisms of inheritance. Mendel hypothesized about what the offspring of various pea plants would look like. From these experiments, he discovered the “Laws of Inheritance.” The Laws of Inheritance state that traits of the parents are passed to their offspring Mendel’s discoveries p ...
... understand the mechanisms of inheritance. Mendel hypothesized about what the offspring of various pea plants would look like. From these experiments, he discovered the “Laws of Inheritance.” The Laws of Inheritance state that traits of the parents are passed to their offspring Mendel’s discoveries p ...
Genome Projector: zoomable genome map with multiple views
... biological context for the visualisation and interpretation of data, and serve as a gateway to information stored in a database [2]. For example, the popular two-dimensional genome map viewer, Gbrowse, provides an entry point for browsing the model organism genome database, GMOD [3], and biochemical ...
... biological context for the visualisation and interpretation of data, and serve as a gateway to information stored in a database [2]. For example, the popular two-dimensional genome map viewer, Gbrowse, provides an entry point for browsing the model organism genome database, GMOD [3], and biochemical ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.