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Introduction to Bioinformatics
Introduction to Bioinformatics

... specifying a protein of about ? (how many) amino acids  Humans have about 35,000 genes = 40,000,000 DNA bps = 3% of total DNA in genome  Human have another 2,960,000,000 bps for control information. (e.g. when, where, how long, etc…) ...
Document
Document

... • Frequency of recessive alleles – in many instances the recessive allele is much more common than the dominant allele – polydactally (6 or more digits) is a dominant trait but only expressed in ~1/400 births because the majority of the population is homozygous for the recessive gene ...
Spring 2011 Midterm Review Answers
Spring 2011 Midterm Review Answers

... tRNA with the anticodon pairs up with the mRNA sequence The tRNA molecules carry the amino acids which are then bound together with a peptide bond to form the protein When the stop codon is reached, the protein is complete and it detaches from the ribosome ...
PRE-AP Stage 3 – Learning Plan
PRE-AP Stage 3 – Learning Plan

... SCAFFOLD: Students will identify the components of DNA and describe how genetic information is carried in DNA. After identifying the components of the structure of DNA, students will explain how DNA is transcribed and translated into amino acids to make proteins. ACCELERATE: PREAP – purines, pyrimid ...
Document
Document

... Ohno’s hypothesis on the role of gene duplication in evolution Question: How do “new” genes arise? Duplications might allow for major mutation in the extra copy of the gene. Over time, mutations could result in a new function for the duplicated gene - essentially a new ...
Heredity Jeopardy Power Point
Heredity Jeopardy Power Point

... What is Mendel’s ratio for dominant to recessive traits? ...
Study Guide: Lecture 1 1. What does “GMO” stand for and what does
Study Guide: Lecture 1 1. What does “GMO” stand for and what does

... 1. What does “GMO” stand for and what does it mean? 2. What is the meaning of a formula such as 2n = 2x = 18? a. How many chromosomes are there in a pollen grain of a plant with this formula? b. How many chromosomes are there in a leaf cell of a plant with this formula? c. What ploidy level is a pla ...
Biology Professor, Robert Osuna, Receives National Science
Biology Professor, Robert Osuna, Receives National Science

... involved in a variety of important cellular processes. DksA differs from most bacterial gene regulators in that it functions by binding directly to the RNA polymerase enzyme (the enzyme responsible for carrying out transcription) rather than to DNA. Little is known about how DksA itself is regulated ...
GENETICS EOCT STUDY GUIDE 1. DNA Bases: Guanine RNA
GENETICS EOCT STUDY GUIDE 1. DNA Bases: Guanine RNA

... pass on these mutations to their offspring experience an increased risk of cancer develop entirely new DNA sequences in all cells experience difficulties replicating RNA ...
Chapter 5
Chapter 5

... Gene conversion between multiple copies allows the active genes to be maintained during evolution. ...
3.13 Review
3.13 Review

...  Quiz-Quiz-Trade  Pedigree Review  Independent Work  Exit Question ...
What is RNA, and How Does it Differ from DNA?
What is RNA, and How Does it Differ from DNA?

... – Oncogenes: genes that are associated with high rates of cancers – Tumor-suppressor genes: if mutated, more likely to develop cancer ...
Nucleus - Control Center of cell
Nucleus - Control Center of cell

... Order and number differ. Some molecules of DNA can be base pairs in length ...
DNA, RNA, and Protein
DNA, RNA, and Protein

... • RNA polymerase binds to DNA promoter • DNA strands unwind & separate • RNA polymerase adds free RNA nucleotides to complement 1 strand of DNA bases. ...
notes
notes

... • Gene was identified by genetic mapping (using CF families) • This approach (also applied to many other genetic diseases) uses 100s of DNA polymorphisms all over genome ...
BIOTEK
BIOTEK

... adenovirus vector with its expression cassette enters the cells via specific receptors • (d) Its linear dsDNA ultimately gains access to the cell nucleus, where it functions extra chromosomally and expresses the product of the expression cassette (e). ...
tay-sachs disease - Tay
tay-sachs disease - Tay

... • An allele is an alternative form of a gene that is located at a specific position on a specific chromosome • 2/per gene • They come from our parents whether they carry the trait or not • Recessive= r Dominate= R • Dominant means you are more likely to inherit something from your parents • Recessiv ...
Infection cycle: DNA viruses
Infection cycle: DNA viruses

and MUTYH mutation negative FAP and AFAP patients
and MUTYH mutation negative FAP and AFAP patients

... were analyzed with the 1.0 HuEx arrays from Affymetrix. The exon-arrays include over 40 probes for each gene and four probes (one probeset) for every exon for all well annotated genes. The robust multi-array analysis (RMA) algorithm was used for probeset (gene-level) and (exon-level) intensity analy ...
HANDOUT: CH 18 pt 1 Study
HANDOUT: CH 18 pt 1 Study

... CHAPTER 18 STUDY QUESTIONS, part 1 – Regulation of Gene Expression: Prokaryotes vs. Eukaryotes (p. 351-366) 1) What are the two levels within which metabolic control can occur in bacteria? ...
Text S1.
Text S1.

... Using these settings, the number of edges in one of our gene graphs is approximately equal to the number of genes in the studied organism, and the average vertex degree is approximately 2. ...
Unit 1 DNA and the Genome Summary
Unit 1 DNA and the Genome Summary

... base. These nucleotides join together to form a sugar–phosphate backbone. - Base pairing occurs between the two strands of DNA between adenine, thymine and guanine, cytosine. These base pairs bond by weak hydrogen bonds. - The DNA helix is double stranded, and has an anti-parallel structure, with de ...
Review 16-18
Review 16-18

... EXPLAIN replication in detail EXPLAIN how a gene in a eukaryotic cell is transcribed & translated to produce a protein. Draw these processes & label RNA Polymerase, pre-mRNA, mRNA, introns, exons, spliceosome, ribosome, tRNA, codon, anticodon EXPLAIN what changes may occur to the mRNA b4 it leaves t ...
Mendelian Genetics
Mendelian Genetics

... • Linkage occurs when two genes are close to each other on the same chromosome. . • Genes far apart on the same chromosome assort independently: they are not linked. • Linkage is based on the frequency of crossing over between the two genes. Crossing over occurs in prophase of meiosis 1, where homol ...
dnaprotein synthesis
dnaprotein synthesis

... A. RNA is made from the DNA nucleotide sequence during transcription. 1. RNA polymerase attaches to the beginning of one gene or a group of genes, called the promoter, on the DNA molecule. 2. DNA separates at the hydrogen bonds 3. half the DNA serves as a template to make RNA from nucleotides ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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