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Bacterial Comparative Genomics
Bacterial Comparative Genomics

mRNA
mRNA

... Transcription start = +1 Consensus sequence = –35; TTGACA, recognized by  Pribnow box = -10, TATAAT; determines +1 Terminator sequence: where polymerase stops ...
Nucleic Acids - cpprashanths Chemistry
Nucleic Acids - cpprashanths Chemistry

... • Polymers of nucleic acids are chains of nucleotides joined by condensation reactions • They are held together by covalent bonds between the sugar of one nucleotide and the phosphate of another - called phosphodiester bonds ...
Gene needed for health
Gene needed for health

... The protein made from the mutant gene actually BLOCKS the function of the protein from the normal gene. These mutations are much less common than RECESSIVE mutations. Autosomal dominant mutations lead to MARFAN syndrome. People with this syndrome make a large amount of defective FIBRILLIN, which lea ...
a copy of the Sample Syllabus
a copy of the Sample Syllabus

... Objectives: The fast pace of modern molecular genetics research is driven by major challenges in medicine, agriculture, and industry; and, ultimately, by intellectual curiosity. There is intense public interest in the human genome project and genetic engineering, due in part to fascination with how ...
I. Genetics - LangdonBiology.org
I. Genetics - LangdonBiology.org

... and insertions and deletions which may lead to frameshift mutations. Genetics is the study of how organisms pass their genes to their offspring. There are many different inheritance patterns, the most common of which are described below. ...
Enzymes
Enzymes

... Homeostasis (homeo meaning "same" and stasis meaning "condition") is when an organism keeps its bodily conditions (pH, temperature, amount of oxygen or carbon dioxide in the blood, for example) in a stable condition. It does so by regulating its inner equilibrium. In living things, the study of how ...
Molecular genetics of gene expression
Molecular genetics of gene expression

... Transcription factors: proteins that bind to promoters to affect transcription • Transcriptional activators- Recruits the RNA polymerase complex to the transcription start site by binding to either sequences in the promoter or distant cis-acting elements to increase transcription. • Transcriptional ...
NF1X - BioMed Central
NF1X - BioMed Central

... consensus sequence TTGGC(N)5GCCAA [1], and has been shown to activate replication of adenoviral DNA [2]. It is highly conserved in vertebrates, with chicken and hamster orthologs showing 92% amino acid sequence identity [3]. NF1X is reported to control the expression of a number of different genes i ...
GENETIC ENGINEERING QUESTIONS
GENETIC ENGINEERING QUESTIONS

... b. The amount of DNA produced by PCR doubled with each cycle c. The DNA copies produced by PCR were not accurate copies of the DNA d. The rate at which PCR produced accurate copies fell in later cycles 8. Based on the graph, which of the following might have happened between cycles 12 and 13? a. PCR ...
ANTH 2301 - Week 4 DNA
ANTH 2301 - Week 4 DNA

... Insulin - comprised of 50 amino acids That means that there are 150 base pairs ...
Biology/Life Science CST - Standardized Testing and Reporting (CA
Biology/Life Science CST - Standardized Testing and Reporting (CA

... evolution by natural selection. One of his difficulties in demonstrating the theory, however, was the lack of an example of evolution over a short period of time, which could be observed as it was taking place in nature. Although Darwin was unaware of it, remarkable examples of evolution, which migh ...
origin of genes, the genetic code, and genomes
origin of genes, the genetic code, and genomes

... Origin ...
Exam #2 KEY
Exam #2 KEY

... NOT represent the first amino acid on the encoded polypeptide. Furthermore, the reading frame is set by the first AUG which is preceeded by a ribosome binding site/Shine-Delgarno sequence. a. Imagine that there is an insertion of one nucleotide in the mRNA at arrow #1. What is the effect of this ins ...
Slide 1
Slide 1

... Difficulty: Distinguish genuine RNA-editing from sequencing errors ...
Chapter 15: Chromosomal Basis of Inheritance
Chapter 15: Chromosomal Basis of Inheritance

... -Females that are heterozygous for a certain X chromosome trait can express both traits ...
Review Topics for Final Part 1
Review Topics for Final Part 1

...  Two different classes of synthetases attach the amino acids in slightly different ways  Does it cost energy to “charge” a tRNA with an amino acid? What proofreading mechanism ensures that the right amino acid is added?  Different sequences in varying tRNAs allow recognition by the right syntheta ...
Bio1001Ch13W
Bio1001Ch13W

... Summary- The genetic code uses_ ____________________, or codons, each of which is translated into a specific amino acid. ...
Slide 1
Slide 1

... • Each cell of our body contains 46 chromosomes • They are made of DNA our genetic material • A gene is a segment of DNA along the length of ...
Genes
Genes

...  synthesizing end products ...
Genes do not form channels COMMENTARY
Genes do not form channels COMMENTARY

... over the importance of post-translational regulation of gene products, which is central not only to the findings of the Michard et al. paper itself, but is also one of the most important areas of plant biology (e.g. Amtmann and Blatt 2009; Kaiser and Huber 2001; Plaxton 1996). We suggest that such l ...
Recombination is the principal source of variation in asexually
Recombination is the principal source of variation in asexually

... 70. If an allopolyploid plant that has normal bivalent pairing has the genotype “AaBbCCDD” and each of the loci are on different chromosomes, which of the following phenotypic ratios would you expect if 100 doubled haploids are derived from this plant? a) 1:1 b) 1:1:1:1 c) 1:1:1:1:1 d) 1:1:1:1:1:1 7 ...
Protein Synthesis Powerpoint
Protein Synthesis Powerpoint

... With a single nucleotide, there are only 4 possible codes (41). For two nucleotides, there are only 16 possible codes (42). However, for three nucleotides there are 64 possible codes (43), and that is enough to code for the 20 amino acids. ...
Human Genome
Human Genome

... 4. Merge reads into contigs, starting at the pairwise overlaps with the highest LLR scores. Likely chimeras are not used. 5.A consensus sequence is extracted from the merged sequence, based on voting from the highest adjusted quality scores at any base. ...
STAAR Review 4
STAAR Review 4

... 2. This diagram shows a diploid cell with two pairs of homologous chromosomes. ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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