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Human Genetic Disorders
Human Genetic Disorders

... causing pain and weakness – The allele for it is co-dominant. – People with two sickle cell alleles have it – People with one sickle-cell allele produce both normal and abnormal hemoglobin but don’t usually have symptoms. There are treatments but no cure. ...
1 - IGMORIS
1 - IGMORIS

... work plan with environmental safety issues, taking al'1o into consideration the safety to human and animal health when open field experiments are parts of objectives). ...
KEY UNIT TWO TEST – STUDY GUIDE Define primer. A short piece
KEY UNIT TWO TEST – STUDY GUIDE Define primer. A short piece

... A short piece of DNA or RNA that is complementary to a section of template strand and acts as an attachment and starting point for the synthesis strand during DNA replication 2. Define carrier screening Indiscriminate examination of members of a population to detect heterozygotes for serious disorde ...
Chi-Square Analysis
Chi-Square Analysis

... Neither Tim nor Rhoda has Duchenne muscular dystrophy (X-linked recessive disorder), but their firstborn son has it. What is the probability their 2nd child will have it? ...
chapter 15 chromosomal basis of inheritance
chapter 15 chromosomal basis of inheritance

... Morgan Hunt, at Columbia University,1st to associate a specific gene with a specific chromosome, early 1900’s. He studied Drosophila melanogaster and found the eye color of fruit flies is located on the X chromosome. Wild type – most common phenotype in nature, ex. red eyes in fruit fly. Mutant phen ...
Additional traits
Additional traits

... Beyond Mendel’s Laws of Inheritance ...
Imprinting
Imprinting

... Parent Offspring Conflict Hypothesis (Haig hypothesis) Example – The Igf2 gene and its receptor Igf2r • Igf2 (paternally expressed)-if defective=40% reduction in growth • Igf2r (Igf2 receptor)- if defective=increase growth • Igf2-/Igf2r- = normal Another test- Ask if imprinting fails to occur in a ...
How RNA machinery navigates our genomic obstacle
How RNA machinery navigates our genomic obstacle

... our cells. Other researchers had suspected this but had only been able to study it in simplified, modified systems outside the cell. For example, Churchman and her team saw RNA polymerase slow down right before it reached particular obstacles called transcription factors—proteins that help RNA polym ...
Slide 1
Slide 1

... • RNA molecule is single-stranded (rather than double stranded in DNA) • Uracil instead of Thymine. So in RNA Adenine binds with Uracil ...
Mutations - The Super Heroes of Biology
Mutations - The Super Heroes of Biology

... • One nucleotide is replaced by another but it still codes for the same amino acid ...
Chapter 6
Chapter 6

... randomly during gamete formation, and each gamete receives one copy of every factor. • Mendel’s law of independent assortment states that the two alleles for one gene assort independently of the alleles for other genes during gamete formation. Parental genotypes can be inferred from the ratio of phe ...
Note 1
Note 1

... • It is actually a double chain, each chain is called a strand. • A strand consists of repetition of the same nucleotide unit. This unit is formed by a sugar molecule attached to a phosphate residue and a base. ...
Biology
Biology

GENETICS 603 EXAM III Dec. 5, 2002 NAME 5 6 7 8 1 2 4 3 I Gene
GENETICS 603 EXAM III Dec. 5, 2002 NAME 5 6 7 8 1 2 4 3 I Gene

... since the cells fuse all progeny will have mitochondria, unless the petite mutaion is suppressive, in which case it out-replicates the normal mt-DNA and all will be petite. ie all like one parent B) What features of mitochondrial DNA have been useful in tracking human populations? They have a region ...
The Genetic Code - Marengo Community Middle School
The Genetic Code - Marengo Community Middle School

... Genetic code: the dictionary of molecular meaning • Universal: same code used by all organisms on earth • Triplet: 3 bases = one “word” • Unambiguous: each triplet has only one meaning • Degenerate: individual amino acids may be called for by more than one triplet (this is also referred to as redun ...
Test your nucleic acid knowledge!
Test your nucleic acid knowledge!

... DNA is often resuspended in molecular-grade water or _______. ...
Unit 5 DNA/RNA/PROTEIN SYNTHESIS
Unit 5 DNA/RNA/PROTEIN SYNTHESIS

... Translation is the process of interpreting the genetic message and building the protein and begins when the mRNA attaches to a ribosome, which contains proteins and ribosomal RNA (rRNA), in the cytoplasm.  The function of ribosomes is to assemble proteins according to the code that the mRNA brings ...
ppt
ppt

... Given a multiple alignment (of protein coding DNA) we can convert the DNA to proteins. We can then try to model the phylogenetic relations between the proteins using a fixed rate matrix Q, some phylogeney T and branch lengths ti When modeling hundreds/thousands amino acid sequences, we cannot learn ...
Genetics - FW Johnson Collegiate
Genetics - FW Johnson Collegiate

...  Chromosomes contain the information that controls almost everything in our body (how we look, act, etc.)  Humans have 46 chromosomes (23 pairs) that are grouped into homologous (similar) pairs  One of the pairs are called the “sex chromosomes”. These determine what sex we are  Males have an XY ...
Chapter 19
Chapter 19

... 2. Unregulated hunting & habitat removal ...
DNA, RNA and Protein
DNA, RNA and Protein

... build the house of your dreams. If this scenario described the central dogma of biology, which represents protein? ...
Exam 2 Key v3 Bio200 Win16
Exam 2 Key v3 Bio200 Win16

... 5/ 3a) Short chromosomes are copied well. Longer chromosomes are either delayed, or the interior regions of the DNA are never completely replicated. _____ Synonymous mutation in the gene encoding the helicase enzyme _____ Mutation in the promoter regions of all genes encoding DNA polymerase enzymes ...
Learning objectives
Learning objectives

... 6. Describe the role of an expression vector. 7. Describe two advantages of using yeast cells instead of bacteria as hosts for cloning or expressing eukaryotic genes. 8. Describe the structure and function of a yeast artificial chromosome (YAC). 9. Describe two techniques to introduce recombinant DN ...
Slides - Department of Computer Science
Slides - Department of Computer Science

... • Every cell contains the same genomic information – Except sperms and eggs, which only contain half of the genome ...
Learning objectives
Learning objectives

... 6. Describe the role of an expression vector. 7. Describe two advantages of using yeast cells instead of bacteria as hosts for cloning or expressing eukaryotic genes. 8. Describe the structure and function of a yeast artificial chromosome (YAC). 9. Describe two techniques to introduce recombinant DN ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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