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(i) C
(i) C

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When wood, paper, and wax are burned, they ap

... oranges contains 12 oranges, 1 mole of hydrogen atoms contains 6.022  1023 H atoms. Figure 3.1 shows 1 mole each of several common elements. We have seen that 1 mole of carbon-12 atoms has a mass of exactly 12 g and contains 6.022  1023 atoms. This mass of carbon-12 is its molar mass (), defined ...
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Chapter 2: Atoms, Ions, and the Periodic Table
Chapter 2: Atoms, Ions, and the Periodic Table

... C) The mass of the products of a chemical reaction is equal to the mass of the starting materials of the reaction. D) When a metal reacts with oxygen, the oxygen content of the products is fixed at one or two values. E) When water is broken down into its elements by electrolysis, elemental oxygen an ...
Chapter 2: Atoms, Ions, and the Periodic Table
Chapter 2: Atoms, Ions, and the Periodic Table

... C) The mass of the products of a chemical reaction is equal to the mass of the starting materials of the reaction. D) When a metal reacts with oxygen, the oxygen content of the products is fixed at one or two values. E) When water is broken down into its elements by electrolysis, elemental oxygen an ...
FREE Sample Here
FREE Sample Here

... C) The mass of the products of a chemical reaction is equal to the mass of the starting materials of the reaction. D) When a metal reacts with oxygen, the oxygen content of the products is fixed at one or two values. E) When water is broken down into its elements by electrolysis, elemental oxygen an ...
Chapter 2: Atoms, Ions, and the Periodic Table
Chapter 2: Atoms, Ions, and the Periodic Table

... C) The mass of the products of a chemical reaction is equal to the mass of the starting materials of the reaction. D) When a metal reacts with oxygen, the oxygen content of the products is fixed at one or two values. E) When water is broken down into its elements by electrolysis, elemental oxygen an ...
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Isotopic labeling



Isotopic labeling (or isotopic labelling) is a technique used to track the passage of an isotope, or an atom with a variation, through a reaction, metabolic pathway, or cell. The reactant is 'labeled' by replacing specific atoms by their isotope. The reactant is then allowed to undergo the reaction. The position of the isotopes in the products is measured to determine the sequence the isotopic atom followed in the reaction or the cell's metabolic pathway. The nuclides used in isotopic labeling may be stable nuclides or radionuclides. In the latter case, the labeling is called radiolabeling.In isotopic labeling, there are multiple ways to detect the presence of labeling isotopes; through their mass, vibrational mode, or radioactive decay. Mass spectrometry detects the difference in an isotope's mass, while infrared spectroscopy detects the difference in the isotope's vibrational modes. Nuclear magnetic resonance detects atoms with different gyromagnetic ratios. The radioactive decay can be detected through an ionization chamber or autoradiographs of gels.An example of the use of isotopic labeling is the study of phenol (C6H5OH) in water by replacing common hydrogen (protium) with deuterium (deuterium labeling). Upon adding phenol to deuterated water (water containing D2O in addition to the usual H2O), the substitution of deuterium for the hydrogen is observed in phenol's hydroxyl group (resulting in C6H5OD), indicating that phenol readily undergoes hydrogen-exchange reactions with water. Only the hydroxyl group was affected, indicating that the other 5 hydrogen atoms did not participate in these exchange reactions.
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