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chemistry paper 1
chemistry paper 1

... Members of higher molecular mass are often used to make soap. The first few members are often used to make polymers. The members can commonly react with hydrogen halides to give halohydrocarbons. A. ...
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... Rancidity: The oily and fatty food oxidizes and give bad smell and test is called rancidity.Preventatioin:By adding antioxidant which slow down the process of oxidation.2. Vaccum packing,3Flusing N2 gas in chips packets.3.Refrigeration. Q.Explain the various types of reactions with one example of ea ...
Gr. 11 Chemistry Student Workbook (Spring 2016)
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... One of the most important educational skills you can develop is how to monitor and track your own learning. Either at the end of class or at home, you will complete a daily entry in your learning log. Written Work: Use our marking scheme for daily class work (out of 5) to assess your written work. W ...
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Bioorthogonal chemistry



The term bioorthogonal chemistry refers to any chemical reaction that can occur inside of living systems without interfering with native biochemical processes. The term was coined by Carolyn R. Bertozzi in 2003. Since its introduction, the concept of the bioorthogonal reaction has enabled the study of biomolecules such as glycans, proteins, and lipids in real time in living systems without cellular toxicity. A number of chemical ligation strategies have been developed that fulfill the requirements of bioorthogonality, including the 1,3-dipolar cycloaddition between azides and cyclooctynes (also termed copper-free click chemistry), between nitrones and cyclooctynes, oxime/hydrazone formation from aldehydes and ketones, the tetrazine ligation, the isocyanide-based click reaction, and most recently, the quadricyclane ligation.The use of bioorthogonal chemistry typically proceeds in two steps. First, a cellular substrate is modified with a bioorthogonal functional group (chemical reporter) and introduced to the cell; substrates include metabolites, enzyme inhibitors, etc. The chemical reporter must not alter the structure of the substrate dramatically to avoid affecting its bioactivity. Secondly, a probe containing the complementary functional group is introduced to react and label the substrate.Although effective bioorthogonal reactions such as copper-free click chemistry have been developed, development of new reactions continues to generate orthogonal methods for labeling to allow multiple methods of labeling to be used in the same biosystems.
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