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The Chemistry of Burgers
The Chemistry of Burgers

... meat patty wasn’t exposed to the high temperature of the pan and so it wasn’t able to undergo the hightemperature Maillard reaction, which create these nice crusty brown bits that are very flavorful to us. KIRSHENBAUM: The Maillard reactions result in development of rich brown colors. And they also ...
Practice Exam-Final Fall 2016 W-Ans
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... 16. How many hydrogen atoms are there in 48.0 g of CH4? (a) 1.81x1023 (b) 7.22x1024 (c) 6.02x1023 (d) 1.20x1025 (e) 4.70x1025 Hint: According to the chemical formula, one mole of CH4 contains 1 mole of C atoms and 4 moles of hydrogen atoms. Thus, the mole of H = 4 x {mass of CH4/molar mass of CH4}. ...
MOLES AND CALCULATIONS USING THE MOLE CONCEPT
MOLES AND CALCULATIONS USING THE MOLE CONCEPT

... 1. A mole is the amount of any substance that contains as many elementary entities as there are atoms in exactly 1.00 g of hydrogen-1. 2. A mole is the amount ... in exactly 12.00 g of carbon-12. 3. 6.02 x 1023 of anything 4. It is important to state the entities involved: ...
Thermochemistry - University of Missouri
Thermochemistry - University of Missouri

... change in enthalpy is the same whether the reaction takes place in one step or in a series of steps. (Enthalpy is a state function. It doesn’t matter how you get there, only where you start and end.) ...
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Belarus, National Final, 2001 (PDF 149K).
Belarus, National Final, 2001 (PDF 149K).

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Energetics - chemistryatdulwich
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Atomic Theory (2
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... 3.) At what temperature would 2.10 moles of N2 gas have a pressure of 1.25 atm and in a 25.0 L tank? 4.) What volume is occupied by 5.03 g of O2 at 28°C and a pressure of 0.998atm? 5.) What is the volume of 1.00 mole of a gas at standard temperature and pressure? 6.) A gas takes up a volume of 17 li ...
CHEMISTRY
CHEMISTRY

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Phenomenological description of the transition state, and the bond
Phenomenological description of the transition state, and the bond

... dynamics are ‘‘frozen out’’, and thus one should be able to observe the complete evolution of the chemical event, starting from time zero, passing through transition states, and ultimately forming products’’. Although most femtochemistry studies deal with excited-state processes, ground-state proces ...
The Copper Cycle
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... Acids and Bases In general, acids are compounds that produce hydrogen ions (H+), also called protons. Acids can also be defined as substances that produce hydronium ions (H3O+), which is a hydrogen ion combined with a water molecule: H+(aq) + H2O(l) → H3O+(aq). The two equations below both represent ...
Final Exam SG Part 1 (Unit 5).
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Chemistry Curriculum

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Classifying Chemical Reactions by What Atoms Do

... been just enough titrant added to complete the reaction. In acid-base titrations, because both the reactant and product solutions are colorless, a chemical (indicator) is added that changes color when the solution undergoes large changes in acidity/alkalinity At the endpoint of an acid-base titratio ...
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- Catalyst

... Step 1) Assign oxidation numbers to all elements in the equation. Step 2) From the changes in oxidation numbers, identify the oxidized and reduced species. Step 3) Compute the number of electrons lost in the oxidation and gained in the reduction from the oxidation number changes. Draw tie-lines betw ...
molecular vibrations: from harmonic oscillators to pendulums
molecular vibrations: from harmonic oscillators to pendulums

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Bioorthogonal chemistry



The term bioorthogonal chemistry refers to any chemical reaction that can occur inside of living systems without interfering with native biochemical processes. The term was coined by Carolyn R. Bertozzi in 2003. Since its introduction, the concept of the bioorthogonal reaction has enabled the study of biomolecules such as glycans, proteins, and lipids in real time in living systems without cellular toxicity. A number of chemical ligation strategies have been developed that fulfill the requirements of bioorthogonality, including the 1,3-dipolar cycloaddition between azides and cyclooctynes (also termed copper-free click chemistry), between nitrones and cyclooctynes, oxime/hydrazone formation from aldehydes and ketones, the tetrazine ligation, the isocyanide-based click reaction, and most recently, the quadricyclane ligation.The use of bioorthogonal chemistry typically proceeds in two steps. First, a cellular substrate is modified with a bioorthogonal functional group (chemical reporter) and introduced to the cell; substrates include metabolites, enzyme inhibitors, etc. The chemical reporter must not alter the structure of the substrate dramatically to avoid affecting its bioactivity. Secondly, a probe containing the complementary functional group is introduced to react and label the substrate.Although effective bioorthogonal reactions such as copper-free click chemistry have been developed, development of new reactions continues to generate orthogonal methods for labeling to allow multiple methods of labeling to be used in the same biosystems.
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