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H1N1 Influenza A (Swine flu) Update
H1N1 Influenza A (Swine flu) Update

... Mexican health officials have reported several hundred suspect cases, including several deaths associated with confirmed swine influenza A (H1N1) virus infection. In Mexico, many patients have experienced rapidly progressive pneumonia, respiratory failure requiring mechanical ventilation & acute res ...
Talking Points
Talking Points

... surgical mask to avoid spreading the illness to the infant. ...
Pandemic Response Lessons from Influenza H1N1 2009 in Asia
Pandemic Response Lessons from Influenza H1N1 2009 in Asia

... reported in the Western Pacific and South-East Asian regions respectively.11 Although the number of confirmed cases quickly increased, accuracy in reporting decreased with the recommendation to “stop testing, just treat when clinically suspected and indicated”. This was made on July 16 2009, since m ...
Infection Prevention for all KCI and KCC Staff
Infection Prevention for all KCI and KCC Staff

...  The most frequent cause of vaccine-preventable death in the US. Causes 24,000 deaths per year and 150,000 hospitalizations per year ...
Pandemic Influenza - Massachusetts Medical Society
Pandemic Influenza - Massachusetts Medical Society

... Median age of those infected -18 years (90% of cases < 40 years) –the young and healthy Incubation ~ 3-5 days - Illness starts out as typical influenza – fever, myalgia, sore throat, cough, may progress to diffuse viral pneumonia often leading to ARDS and death. Currently case fatality (> 60%) is mu ...
Click here for handout
Click here for handout

... children were getting very sick with H1N1, not the elderly, as expected with seasonal flu Children at high risk for serious H1N1 complications often had underlying health concerns, like asthma When H1N1 spread through the US, there was a better idea of what to expect-this enabled high risk patients ...
Avian Flu: Preparing for a Pandemic
Avian Flu: Preparing for a Pandemic

... In 1997, an outbreak of avian influenza among poultry in Hong Kong was traced to the H5N1 virus strain (see sidebar on page 5). The outbreak was accompanied by 18 cases of human infection; six of those people died. There was immediate apprehension among world health officials, as this was the first ...
B. Pharm - South African Pharmacist`s Assistant
B. Pharm - South African Pharmacist`s Assistant

... In addition to the above it is recommended that individuals in the agricultural, veterinary and laboratory sectors who are conducting surveillance and/or research into avian influenza are also vaccinated. This recommendation is based on the following considerations: • There is a theoretical risk of ...
My Friend Has the Flu… FAQ`s
My Friend Has the Flu… FAQ`s

My Friend Has the Flu… FAQ`s
My Friend Has the Flu… FAQ`s

... How long can influenza virus remain viable on objects (such as books and doorknobs)?  Studies have shown that influenza virus can survive on environmental surfaces and can infect a person  for 2 to 8 hours after being deposited on the surface.  What surfaces are most likely to be sources of contami ...
Managing infected employees
Managing infected employees

... This section focuses on the management of patients / employees affected by a SEVERE prepandemic or pandemic virus – for example, if H5N1 develops the ability to spread easily from human to human and continues to be a severe infection. As of July 2009, the H1N1 pandemic virus is classified by the WHO ...
ROUND ROCK MEDICAL CENTER
ROUND ROCK MEDICAL CENTER

...  Quickly recognizing unusual clusters of patients presenting with similar illness and reporting increased activity or clusters of symptoms to the local Health Department  Maintaining strict Infection Control practices at all times to prevent the spread of infection among patients, staff and visito ...
Influenza Prevention and Treatment for the 2012-2013
Influenza Prevention and Treatment for the 2012-2013

... patients can not be expected to return for the vaccine when influenza is likely to be circulating in the community. • Vaccination does not cause influenza or influenza-like illness, but a healthy immune response can produce cold-like symptoms following vaccination. ...
- WordPress.com
- WordPress.com

... major change;  Results fro genetic recombination of human with animal/avian virus  Leads to a novel subtype different from both parent viruses  If novel subtype has sufficient genes from H1 viruses which make it readily transmissible from person to person, it may cause pandemic ...
Calculation of High Risk Population and Potential Impacts of Shortage
Calculation of High Risk Population and Potential Impacts of Shortage

... Influenza vaccine can be given to people 6 months of age and older. It is recommended for people who are at risk of serious influenza or its complications, and for people who can spread influenza to those at high risk (including all household members) ...
Avian Influenza Infections in Humans and Poultryof
Avian Influenza Infections in Humans and Poultryof

... Pathogenicity and oseltamivir resistance of LPAI isolated from broilers in Lebanon Although losses from LPAI viruses are lower, compared to those resulting from HPAI; H9N2 LPAI viruses in Lebanon demonstrated an ability to increase their pathogenicity, and host range, following their passaging in di ...
Pandemic Influenza
Pandemic Influenza

... with flu like symptoms:  has difficulty breathing or chest pain  has purple or blue discoloration of the lips  is vomiting and unable to keep liquids down  has signs of dehydration such as dizziness when standing, or absence of urination  has seizures (for example, uncontrolled convulsions)  i ...
H1N1 Influenza A (Swine Flu)
H1N1 Influenza A (Swine Flu)

... on a surface through these steps can reduce the chances of hand transfer of virus. Influenza viruses are susceptible to inactivation by a number of chemical disinfectants readily available from consumer and commercial ...
Upswing in Local Influenza activity
Upswing in Local Influenza activity

... Be aware that influenza activity is on the rise in our community. In fact, both Kitsap County and statewide surveillance data show increases in laboratory positive tests, influenza-like-illness visits, and other measures. Offer influenza vaccine to your patients, especially those who are at high ris ...
Dec. 24
Dec. 24

... positive for avian influenza through blood tests since April, and one of them showed an increase in antibodies confirming an infection. The infected male employee, who had taken two tests, suffered from a sore throat for a few days after taking anti-virus medication. The four other people have not b ...
Poster  - University of Wisconsin Oshkosh
Poster - University of Wisconsin Oshkosh

... In the event of an avian flu pandemic, all the roads entering the city of Oshkosh will be closed and monitored with surveillance 24/7. The military will be in charge of the main roads and highways entering into the city. All the minor roads will be closed and monitored by the local police forces at ...
Swine Flu - A Pandemic Outbreak
Swine Flu - A Pandemic Outbreak

... Facility management includes using disinfectants and ambient temperature to control virus in the environment. The virus is unlikely to survive outside living cells for more than two weeks, except in cold (but above freezing) conditions, and it is readily inactivated by disinfectants. Herd management ...
Oct. 15 - University of Washington
Oct. 15 - University of Washington

... development and thus take advantage of this preventive option. Progress is needed on three fronts. First, countries experiencing outbreaks need to rapidly share human and animal viruses with laboratories in the WHO Global Influenza Surveillance Network. Analysis of these viruses determines the possi ...
The 1918-1919 Influenza Pandemic as covered in The Journal of
The 1918-1919 Influenza Pandemic as covered in The Journal of

... of Pathology, Bacteriology, time believed the cause of and Disinfection, contended that, to establish etiological influenza to be bacterial. German physician Richard Pfeiffer significance, it was not sufficient merely to establish had isolated bacteria from influenza patients during the the presence of ...
Tamiflu: To Stockpile or Not to Stockpile
Tamiflu: To Stockpile or Not to Stockpile

... substitution in neuraminidase conferring high-level resistance to oseltamivir was isolated from two of eight Vietnamese patients during oseltamivir treatment. Both patients died of influenza A (H5N1) virus infection, despite early initiation of treatment in one patient. Surviving patients had rapid ...
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Human mortality from H5N1

Human mortality from H5N1 or the human fatality ratio from H5N1 or the case-fatality rate of H5N1 refer to the ratio of the number of confirmed human deaths resulting from confirmed cases of transmission and infection of H5N1 to the number of those confirmed cases. For example, if there are 100 confirmed cases of humans infected with H5N1 and 10 die, then there is a 10% human fatality ratio (or mortality rate). H5N1 flu is a concern due to the global spread of H5N1 that constitutes a pandemic threat. The majority of H5N1 flu cases have been reported in southeast and east Asia. The case-fatality rate is central to pandemic planning. While estimates of case-fatality (CF) rates for past influenza pandemics have ranged from about 0.1% (1957 and 1968 pandemics) to 2.5% (1918 pandemic); the official World Health Organization estimate for the current outbreak of H5N1 avian influenza to date is around 60%. While the real H5N1 CF rate (what it would be if we had perfect knowledge) could be lower (one study suggests that the real H5N1 CF rate is closer to 14–33%); it is unlikely that, if it becomes a pandemic, it will go to the 0.1–0.4% level currently embraced by many pandemic plans.H5N1 infections in humans are generally caused by bird to human transmission of the virus. Until May 2006, the WHO estimate of the number of human to human transmission had been ""two or three cases"". On May 24, 2006, Dr. Julie L. Gerberding, director of the United States Centers for Disease Control and Prevention in Atlanta, estimated that there had been ""at least three."" On May 30, Maria Cheng, a WHO spokeswoman, said there were ""probably about half a dozen,"" but that no one ""has got a solid number."" The cases of suspected human to human transmission that continue to be found have been isolated and contained, and include transmission among members of a family in Sumatra, Indonesia in June 2006 as well as earlier and later instances arising in other countries. However, no pandemic strain of H5N1 has yet been found. The key point is that, at present, ""the virus is not spreading efficiently or sustainably among humans.""H5N1 vaccines for chickens exist and are sometimes used, although there are many difficulties that make it especially difficult to decide whether vaccination will do more harm than good. In the U.S. H5N1 pre-pandemic vaccines exist in quantities sufficient to inoculate a few million people and might be useful for priming to ""boost the immune response to a different H5N1 vaccine tailor-made years later to thwart an emerging pandemic"". Japan has inoculated 6,000 health care workers with a pre-pandemic vaccine, and is planning how to proceed with widespread vaccinations, particularly workers who would provide utilities during an outbreak. Switzerland is also considering preemptive vaccination to protect the general public. H5N1 pandemic vaccines and the technologies to rapidly create them are in the H5N1 clinical trials stage but cannot be verified as useful until after a pandemic strain emerges. Efforts to identify the changes that might result in a human-communicable strain have resulted in laboratory-generated H5N1 with substantially greater affinity for human cellular receptors after a change of just two of the H5 surface proteins. Significantly, mouse antibodies were 10 times less potent against the mutants than against the pre-mutated viruses.
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