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htp Pseudomonas aeruginosa AMANDA SWANEPOEL
htp Pseudomonas aeruginosa AMANDA SWANEPOEL

Requirement for chitin biosynthesis in epithelial tube morphogenesis. Proc. Natl. Acad. Sci. USA 102: 17014-17019. pdf
Requirement for chitin biosynthesis in epithelial tube morphogenesis. Proc. Natl. Acad. Sci. USA 102: 17014-17019. pdf

... tubes that transport vital fluids or gases. The proper size and shape of tubes are crucial for their transport function, but the molecular processes that govern tube size and shape are not well understood. Here we show that three genes required for tracheal tube morphogenesis in Drosophila melanogas ...
org.Mm.eg.db
org.Mm.eg.db

... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
informe tecnológico de patentes
informe tecnológico de patentes

... disorder caused by the expression of mutant huntingtin protein (Htt). Suppression of Htt expression, using RNA interference, might be an effective therapy. However, if reduction of wild-type protein is not well tolerated in the brain, it may be necessary to suppress just the product of the mutant al ...
The daily rhythm of mice
The daily rhythm of mice

... oscillator. An interesting avenue in this context is the study of epigenetic regulation of gene expression reviewed in this issue by Merrow and Ripperger. 3. Lessons from mice Forward genetics, as mentioned above, provides information on the phenotype, the responsible mutation and sometimes allows d ...
Tandem Genetic Duplications in Phage and Bacteria
Tandem Genetic Duplications in Phage and Bacteria

... of these events involve legitimate recombination between homologous sequences, they might be expected to occur frequently. EXTREMELY LARGE DUPLICATIONS CAN BE TRANSDUCED As mentioned earlier, the only novel base sequence in chromosomes carrying a duplication is the join point between copies of the d ...
MSc Seminar: Donald Dunbar
MSc Seminar: Donald Dunbar

... Non specific binding of labelled target  Need to exclude this background  Several methods exist ...
Gbx2 is required for the morphogenesis of the mouse inner ear
Gbx2 is required for the morphogenesis of the mouse inner ear

... of phenotypes was observed. We divided the specimens into four categories (I, II, III and IV), based on the severity of the phenotype (Fig. 2, Table 1). Overall, Gbx2 mutant inner ears are usually missing the endolymphatic duct (Table 1, n=18/19), with an enlarged membranous labyrinth (Fig. 2A). By ...
Mende an the Gee 11I+t
Mende an the Gee 11I+t

... area, Mendel and the other children received agricultural training in school along with their basic education. As an adolescent, Mendel overcame financial hardship and illness to excel in high school and, later, at the Olmutz Philosophical Institute. In 1843, at the age of21, Mendel entered an Augu ...
Risk assessment - Office of the Gene Technology Regulator
Risk assessment - Office of the Gene Technology Regulator

... might give rise to harm to people or the environment. These 16 events included consideration of whether, or not, expression of the introduced genes could result in products that are toxic or allergenic to people or other organisms, alter characteristics that may impact on the spread and persistence ...
Histological classification and molecular genetics of meningiomas
Histological classification and molecular genetics of meningiomas

... five following criteria may lead to the diagnosis of atypical meningioma: increased cellularity, high nuclear to cytoplasmic ratio (small cells), prominent nucleoli, uninterrupted patternless or sheet-like growth, and foci of spontaneous (not induced by embolism) necrosis. The issue of brain invasion ...
Genetics - Brook Biology
Genetics - Brook Biology

... Gene Expression  Multicellular organisms need a variety of cell types to perform specific functions for the organism; therefore, individual cells differentiate and become specialized in structure and function. • Differentiation happens due to selective gene expression – some genes are turned off, ...
FUNCTIONAL INVESTIGATION OF ARABIDOPSIS
FUNCTIONAL INVESTIGATION OF ARABIDOPSIS

... Callose synthesis occurs at specific stages of cell wall development in all cell types, and in response to pathogen attack, wounding and physiological stresses. We isolated promoters of 12 Arabidopsis callose synthase (CalS1-12) genes and demonstrated that different callose synthases are expressed s ...
Alu
Alu

... Place K points into the space represented by the objects that are being clustered. These points represent initial group centroids.  Assign each object to the group that has the closest centroid.  When all objects have been assigned, recalculate the positions of the K centroids.  Repeat Steps 2 an ...
The Nodal Pathway Acts Upstream of Hedgehog
The Nodal Pathway Acts Upstream of Hedgehog

... 1998). However, the source, exact role, site, and time of action of Hh proteins during anterior CNS patterning remain uncertain. For instance, although shh is expressed within the telencephalon, the endogenous source of Hh proteins that influence early development of this region are uncertain and pr ...
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PDF

... AEL, corresponding to the first and second larval instars. Adult progeny of the appropriate genotype were collected and preserved in 70 % alcohol. In the case of flies irradiated during the first instar, most induced yf36a clones are expected to be sufficiently large to be detectable at low (x25) ma ...
Nodal signaling and the zebrafish organizer
Nodal signaling and the zebrafish organizer

... These mutant phenotypes strongly resemble previously described defects induced by overactivation or inhibition of BMP signaling in Xenopus (De Robertis and Sasai, 1996; Harland and Gerhart, 1997). Indeed, epistatic analysis and molecular cloning has identified five genes of the dorsal-ventral group ...
Deciphering the Galaxy Guppy phenotype
Deciphering the Galaxy Guppy phenotype

... you see a continuous varying trait you can assume it is due to multiple genes, not a single gene. That is why it is so difficult to distinguish between a lace, a cobra, a coarse snakeskin, or whatever term people will try to use to describe a pattern. So even if an international body managed to hamm ...
Educator Materials
Educator Materials

... represented using a nucleotide that differs between the alleles (for example, A, G). Some representations are more complex, such as the alleles for human ABO blood type (IA, IB, i), which is used to show the two codominant alleles (I) and the recessive O allele (i), using superscripts to distinguish ...
Auxin signals — turning genes on and turning cells around
Auxin signals — turning genes on and turning cells around

... Key to our present understanding of auxin-controlled gene expression are transcripts that are rapidly induced by auxin, which are collectively referred to as primary auxin-response genes [4]. In Arabidopsis, these include several families of well-characterized genes [5], including many of the 29 mem ...
Loss of heterozygosity at D8S262: an early genetic event of
Loss of heterozygosity at D8S262: an early genetic event of

... cancer progression. Single-nucleotide polymorphism (SNP) arrays have been used to detect genome-wide abnormalities, such as copy number changes that include loss of heterozygosity (LOH), deletions, and gene amplification events in various types of cancer, and localization of the regions of many onco ...
chromosomal
chromosomal

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Plant Functional Genomics Plant Functional Genomics
Plant Functional Genomics Plant Functional Genomics

... library construction. Because individual clones of the BAC library will be picked, stored, arrayed on filters, and directly used for mapping and sequencing, a BAC library with a small average insert size and high empty clone (no inserts) rate will dramatically increase the cost and labor for subsequ ...
IVRI OB 1809
IVRI OB 1809

... which differed in one recognisable respect: one was tall, the oth<;r dwarf. The first generation, or F I , progeny were all ~tall, but when they were self-pollinated they produced second generation, or F 2 , progeny three-quarters of which were tall and one-quarter dwarf. The dwarfall bred true, and ...
A Common Polygenic Basis for Quinine and
A Common Polygenic Basis for Quinine and

... phenotypes to both compounds in pilot tests (strong avoidance and relative indifference respectively). They were also known to carry the Soab (nontaster) and Soac (demitaster) alleles respectively (Harder et al., 1992). Polygenic control of quinine avoidance had been found in serial backcross genera ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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