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Statistical analysis of simple repeats in the human genome
Statistical analysis of simple repeats in the human genome

... Experiments on kinetics of DNA denaturation and renaturation and the analysis of DNA sequences have revealed that most of our genome is populated by DNA repeats of different length, number and degree of dispersion [1]. Long repeats in few copies are usually orthologous genes, which may contain hidde ...
A Common Polygenic Basis for Quinine and
A Common Polygenic Basis for Quinine and

... phenotypes to both compounds in pilot tests (strong avoidance and relative indifference respectively). They were also known to carry the Soab (nontaster) and Soac (demitaster) alleles respectively (Harder et al., 1992). Polygenic control of quinine avoidance had been found in serial backcross genera ...
lilliputian - Development - The Company of Biologists
lilliputian - Development - The Company of Biologists

... blastoderm-specific transcripts are not known, genetic evidence suggests that the onset of expression of the Sry α and nullo genes might depend on maternal gene products rather than a unique zygotically active regulator (Merrill et al., 1988; Wieschaus and Sweeton, 1988; Simpson-Rose and Wieschaus, ...
A gain of function mutation causing skeletal overgrowth in the
A gain of function mutation causing skeletal overgrowth in the

... (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critical region. All five genes are located on the same strand. Marker positions are shown along with their number of crossovers from rapunzel (see Supplemental data for more details rega ...
Running Head: THE GENDER ASSOCIATION OF DYSLEXIA THE
Running Head: THE GENDER ASSOCIATION OF DYSLEXIA THE

... that has been accomplished in each child rather than the dyslexic difference in each child. There are also a few other limitations to this study. First of all, the amount of things like tests that are required result in a very costly study, especially since the size sample is large, with 120 childre ...
REVIEWS
REVIEWS

... a bona fide neural crest, Slug (a Snail family member) seems to be involved in neural-crest specification in both the chick and Xenopus embryos9,14,45,46. Having been specified, both the mesoderm and the neural crest have to delaminate from the tissue in which they originate — the PRIMITIVE STREAK a ...
Cytogenetic Analysis Shows that the Unusually Large Chromosome
Cytogenetic Analysis Shows that the Unusually Large Chromosome

... (black larval marking) silkworm (Bombyx mori) strain (TWPB). We have analyzed the composition and arrangement of this large chromosome. A genetic linkage analysis shows that the large chromosome is made up of the W chromosome, the second chromosome fragment (p fragment), and the fifth chromosome (li ...
Lecture 15 Notes CH.14
Lecture 15 Notes CH.14

... The factor for white flowers was not diluted or destroyed because it reappeared in the F2 generation ...
Gene Section EVI1 (ecotropic viral integration site 1 (EVI1) and
Gene Section EVI1 (ecotropic viral integration site 1 (EVI1) and

... absent limb buds, a pale yolk sac and placenta, abnormal development of the nervous system and the heart, and massive haemorrhaging. EVI1 is thought to exert its biological functions mainly by acting as a transcription factor. In addition, however, EVI1 has been reported to inhibit c-jun Nterminal k ...
Chromosome location and characterization of genes for grain
Chromosome location and characterization of genes for grain

... higher grain yield than their recurrent parent, LDN (303.6 g m-1); though none were significantly higher. Nine LDN-DIC lines did not differ significantly from LDN for grain yield. The three lines LDN(521-3A) (207.4 g m-1), LDN(742-2B) (212.2 g m-1), and LDN(742-7B) (233.7 g m-1) had the lowest yield ...
BMC Developmental Biology
BMC Developmental Biology

... Background: Expression of the mouse Delta-like 1 (Dll1) gene in the presomitic mesoderm and in the caudal halves of somites of the developing embryo is required for the formation of epithelial somites and for the maintenance of caudal somite identity, respectively. The rostro-caudal polarity of somi ...
MOLECULAR RECOGNITION AND RESPONSE IN POLLEN AND
MOLECULAR RECOGNITION AND RESPONSE IN POLLEN AND

... parent (sporophyte). In the simplest case, the pollen is recognized by the pistil as self if either of the two S-haplotypes carried by its parent matches one of the two S-haplotypes carried by the pistil. Thus crosses between two plants are possible only if their S-genotypes do not share any haploty ...
version pdf - Atlas of Genetics and Cytogenetics in Oncology and
version pdf - Atlas of Genetics and Cytogenetics in Oncology and

... Patients with chromosome aberrations always have a distinct clinical picture. They resemble each other as a group Many, but not all chromosome aberrations, cause a highly distinct pattern of abnormalities; patients with these aberrations resemble each other more than their sibs and parents Although ...
Supplementary Information (doc 132K)
Supplementary Information (doc 132K)

... other functional elements in the region are as noted. QTL (eQTL) columns list genes whose expression or methylation levels (m) are associated (P-value) with the specified SNP in that row, specifically as identified previously in EU-ancestry frontal (F), parietal (P) or cerebellar (C) tissue. mQTL an ...
Foundations of Biology - Geoscience Research Institute
Foundations of Biology - Geoscience Research Institute

... Example - If one card in a deck of 52 is the queen of hearts, and hearts make up 1/4 of the deck, if you have a card with hearts on it, what are the odds that it is the queen of hearts? Probability queen of hearts/probability of hearts = ...
C3H/HeJ
C3H/HeJ

... between APN, an in-house strain with low CYP1A2 expression, and C3H/HeJ, a laboratory strain expressing normal CYP1A2 levels, determined that this phenotype is mediated by three quantitative trait loci (QTL) localized to chromosomes 1, 4 and 9, as previously reported. The QTL on chromosome 9 co-loca ...
PDF manual - QIAGEN Bioinformatics
PDF manual - QIAGEN Bioinformatics

... all entries in sequence lists where one or more of the reads is 56bp or longer. The mapping parameters are: • Maximum number of mismatches. This parameter is available if you have selected at least one sequence list containing only short reads (shorter than 56 nucleotides, except in the case of colo ...
Gene Section USP1 (ubiquitin specific peptidase 1) Atlas of Genetics and Cytogenetics
Gene Section USP1 (ubiquitin specific peptidase 1) Atlas of Genetics and Cytogenetics

Genetic studies of psoriasis and psoriatic arthritis
Genetic studies of psoriasis and psoriatic arthritis

... region on chromosome 3q21. Another purpose was to investigate whether several autoimmuneassociating genes and genomic regions are susceptibility factors for psoriasis/psoriatic arthritis. Association studies on a psoriatic arthritis case-control material revealed an association with a marker in the ...
C 2:  A A -
C 2: A A -

... but also imipenem to a minor extent. This enzyme was identified in P. aeruginosa from a university hospital in Pretoria, South Africa, and was associated with an outbreak occurring in the same hospital from March to July 2000 (51). Seventy-two ceftazidimeresistant isolates were isolated from nine pa ...
Role of sexlinked genes in quantitative inheritance
Role of sexlinked genes in quantitative inheritance

... environmental effects and interactions, providing variances are increased by the amount of variance of this origin. In this discussion we will be concerned with the contribution of sex­ linked genes to quantitative characteristics. ...
Expert Reviews in Molecular Medicine Androgenetic alopecia
Expert Reviews in Molecular Medicine Androgenetic alopecia

... receptor, a member of the steroid-thyroid hormone nuclear receptor superfamily. The structure of the androgen receptor includes a ligand-binding domain and a DNA-binding domain. Both testosterone and DHT can bind to the ligand domain, which activates the DNAbinding domain. The receptor–ligand comple ...
Role of Hereditary Factors in Weight Loss and Its
Role of Hereditary Factors in Weight Loss and Its

... Role of genetic factors in development of obesity The regulation of body weight and energy homeostasis is subject to complex regulatory mechanisms that maintain balance between energy intake, energy expenditure and energy stores. Genetic factors play an important role in this regulation as well as i ...
A Plastid in the Making: Evidence for a Second
A Plastid in the Making: Evidence for a Second

... One of the major steps in the evolution of life was the origin of photosynthesis in nucleated cells underpinning the evolution of plants. It is well accepted that this evolutionary process was initiated when a photosynthetic bacterium (a cyanobacterium) was taken up by a colorless host cell, probabl ...
Systematic Studies on the Family Cucurbitaceae
Systematic Studies on the Family Cucurbitaceae

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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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