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mendelian genetics
mendelian genetics

... MENDELIAN GENETICS Law of Independent Assortment  Random distribution of alleles occurs during gamete formation  Genes on separate chromosomes sort independently during meiosis. ...
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... • Coefficient of relatedness (r): represents the average % of genes that two individuals will share based upon their relationship. A parent will contribute half of its alleles (forms of each gene) to an offspring (r=0.5). The coefficient is 0.5 for full siblings etc. ...
Genetics
Genetics

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Microarray Database - Asia University, Taiwan
Microarray Database - Asia University, Taiwan

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introduction to molecular genetics

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Mendelian Genetics - Home | Phoenix College
Mendelian Genetics - Home | Phoenix College

... • What are the father’s phenotype and genotype? • How many different genotypes could result from this cross? How many different phenotypes? ...
Affymetrix Resequencing Arrays
Affymetrix Resequencing Arrays

... Autosomal recessive disorders are a major cause of infant morbidity and mortality Significantly higher in WM than rest of country (Bundy report, 1990) Clinical phenotypes can be caused by mutations in one of several genes or different mutated genes can cause very similar clinical phenotype Genes are ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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