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Intellectual property rights and innovation: Evidence from
... My empirical analysis relies on a newly-constructed data set that traces out the distribution of Celera’s IP across the human genome over time, linked to gene-level measures of scientific research and product development outcomes. Whereas in most contexts it is not straightforward to trace the path ...
... My empirical analysis relies on a newly-constructed data set that traces out the distribution of Celera’s IP across the human genome over time, linked to gene-level measures of scientific research and product development outcomes. Whereas in most contexts it is not straightforward to trace the path ...
Exome sequencing as a tool for Mendelian disease gene discovery
... The systematic identification of rare alleles (that is, with a minor allele frequency (MAF) ≤ 1%) associated with common traits typically requires resequencing instead of genotyping83 and has therefore been challenging. Such studies have largely been limited to assessing rare variants that have been ...
... The systematic identification of rare alleles (that is, with a minor allele frequency (MAF) ≤ 1%) associated with common traits typically requires resequencing instead of genotyping83 and has therefore been challenging. Such studies have largely been limited to assessing rare variants that have been ...
A tandem repeat in decay accelerating factor 1 induced autoimmunity
... further examination identified a tandem repeat in the second intron of Daf1 (Figure 2). Sequencing of this region in a number of mouse strains revealed three different genotypes. DBA/2 mice had the longest repeat sequence with CTTTT (or TTTTC) being repeated 11 times. NZB, NZW, BXSB, B10.S, C57BL/6, ...
... further examination identified a tandem repeat in the second intron of Daf1 (Figure 2). Sequencing of this region in a number of mouse strains revealed three different genotypes. DBA/2 mice had the longest repeat sequence with CTTTT (or TTTTC) being repeated 11 times. NZB, NZW, BXSB, B10.S, C57BL/6, ...
Identification of genes specifically required for the
... a hypothetical protein, whereas Gmet 2410 and Gmet 3229 are predicted to encode a superoxide dismutase, and a thioredoxinrelated protein, respectively. The strain in which Gmet 2833 was deleted was deficient in phenol metabolism as well as benzene metabolism (Figure 2), indicating that this gene of ...
... a hypothetical protein, whereas Gmet 2410 and Gmet 3229 are predicted to encode a superoxide dismutase, and a thioredoxinrelated protein, respectively. The strain in which Gmet 2833 was deleted was deficient in phenol metabolism as well as benzene metabolism (Figure 2), indicating that this gene of ...
BIO 402 - National Open University of Nigeria
... The beginning of cytogenetics and of the chromosome theory of inheritance were clearly outlined by Wilson’s statement that the visible chromomeres on the chromosomes were in all probability much larger than the ultimate dividing units and that these units must be capable of assimilation, growth, and ...
... The beginning of cytogenetics and of the chromosome theory of inheritance were clearly outlined by Wilson’s statement that the visible chromomeres on the chromosomes were in all probability much larger than the ultimate dividing units and that these units must be capable of assimilation, growth, and ...
Heavy Chain Diversity Region Segments of the Channel Catfish
... would not be expected to undergo VJ joining without violating the 12/23 rule of recombination (3). In addition, earlier cDNA analyses revealed sequence diversity within the H chain CDR3 region that was not encoded by VH or JH segments suggesting, that DH segments must contribute to CDR3 diversity in ...
... would not be expected to undergo VJ joining without violating the 12/23 rule of recombination (3). In addition, earlier cDNA analyses revealed sequence diversity within the H chain CDR3 region that was not encoded by VH or JH segments suggesting, that DH segments must contribute to CDR3 diversity in ...
Alu - Environmental
... • Alu elements are only found in the primate branch • Each Alu insertion is a unique event and is inherited from each parent • Most occurred millions of years ago and are often on both pairs of chromosomes • There are Alu elements that have occurred since humans branched from other primates • This g ...
... • Alu elements are only found in the primate branch • Each Alu insertion is a unique event and is inherited from each parent • Most occurred millions of years ago and are often on both pairs of chromosomes • There are Alu elements that have occurred since humans branched from other primates • This g ...
A Unified Approach to the Evolutionary Consequences of Genetic
... combination of genetic and nongenetic mechanisms. Following definitions introduced previously (Bonduriansky and Day 2009), nongenetic mechanisms are mediated by the transmission to offspring of an element of the parental phenotype or environment. The transmissible factor mediating nongenetic inherit ...
... combination of genetic and nongenetic mechanisms. Following definitions introduced previously (Bonduriansky and Day 2009), nongenetic mechanisms are mediated by the transmission to offspring of an element of the parental phenotype or environment. The transmissible factor mediating nongenetic inherit ...
Haemoglobinopathies screening and referral
... In a woman with a confirmed haemoglobin disorder, screening is aimed to identify the fetus at risk and enable informed choice regarding management of an affected infant; and thus partners should be encouraged to participate in screening. However if after careful discussion the partner continues to d ...
... In a woman with a confirmed haemoglobin disorder, screening is aimed to identify the fetus at risk and enable informed choice regarding management of an affected infant; and thus partners should be encouraged to participate in screening. However if after careful discussion the partner continues to d ...
DYAD in meiotic chromosome organisation - Development
... probes which were labelled with 32P. In situ hybridisation was carried out as described earlier (Siddiqi et al., 2000) using antisense riboprobe synthesised from the complete coding region of the DYAD cDNA. Control experiments using sense RNA gave no signal (data not shown). ...
... probes which were labelled with 32P. In situ hybridisation was carried out as described earlier (Siddiqi et al., 2000) using antisense riboprobe synthesised from the complete coding region of the DYAD cDNA. Control experiments using sense RNA gave no signal (data not shown). ...
AN ABSTRACT OF THE THESIS OF Sara R. Fassio for the degree of
... SMF, lack of functional NQR can be expected to reduce SMF-dependent flagella rotation. Since motility is correlated to virulence gene expression (27), we previously proposed that NQR might affect toxT expression via flagella rotation (28). Further characterization of this link, however, revealed tha ...
... SMF, lack of functional NQR can be expected to reduce SMF-dependent flagella rotation. Since motility is correlated to virulence gene expression (27), we previously proposed that NQR might affect toxT expression via flagella rotation (28). Further characterization of this link, however, revealed tha ...
MSc Seminar: Donald Dunbar
... The gene might not be on the chip Can’t differentiate splice variants well The gene might be below detection limit Can’t differentiate RNA synthesis and degradation Can’t tell us about post translational events Bioinformatics can be difficult Relatively expensive February 26th 2011 ...
... The gene might not be on the chip Can’t differentiate splice variants well The gene might be below detection limit Can’t differentiate RNA synthesis and degradation Can’t tell us about post translational events Bioinformatics can be difficult Relatively expensive February 26th 2011 ...
drosophila melanogaster.
... all of the third chromosome where heterozygosity was artificially maintained in the selected region, and to a lesser extent in adjacent regions, due to linkage disequilibrium. I n summary, the results of recombination testing in the GI-Sb interval indicate that in four out of six of the original lin ...
... all of the third chromosome where heterozygosity was artificially maintained in the selected region, and to a lesser extent in adjacent regions, due to linkage disequilibrium. I n summary, the results of recombination testing in the GI-Sb interval indicate that in four out of six of the original lin ...
Reprint
... combination of genetic and nongenetic mechanisms. Following definitions introduced previously (Bonduriansky and Day 2009), nongenetic mechanisms are mediated by the transmission to offspring of an element of the parental phenotype or environment. The transmissible factor mediating nongenetic inherit ...
... combination of genetic and nongenetic mechanisms. Following definitions introduced previously (Bonduriansky and Day 2009), nongenetic mechanisms are mediated by the transmission to offspring of an element of the parental phenotype or environment. The transmissible factor mediating nongenetic inherit ...
Control of Cleavage Cycles in Drosophila Embryos by fru¨ hstart
... for example, there is one more cleavage division than in diploids; in tetraploid embryos there is one fewer (Boveri, 1902). According to a model discussed by Newport and Kirschner (1982), chromosomes titrate a cytoplasmic factor that represses the transition until its level reaches a critical value. ...
... for example, there is one more cleavage division than in diploids; in tetraploid embryos there is one fewer (Boveri, 1902). According to a model discussed by Newport and Kirschner (1982), chromosomes titrate a cytoplasmic factor that represses the transition until its level reaches a critical value. ...
Mendelian Genetics
... Laws Of Probability Because alleles are usually distributed randomly, the laws of probability can describe their behavior: 1 Product Law - Describes the probability of two or more independent events occurring in a defined sequence or way 2 Sum Law - Describes the probability of two or more individu ...
... Laws Of Probability Because alleles are usually distributed randomly, the laws of probability can describe their behavior: 1 Product Law - Describes the probability of two or more independent events occurring in a defined sequence or way 2 Sum Law - Describes the probability of two or more individu ...
IVRI OB 1809
... which differed in one recognisable respect: one was tall, the oth<;r dwarf. The first generation, or F I , progeny were all ~tall, but when they were self-pollinated they produced second generation, or F 2 , progeny three-quarters of which were tall and one-quarter dwarf. The dwarfall bred true, and ...
... which differed in one recognisable respect: one was tall, the oth<;r dwarf. The first generation, or F I , progeny were all ~tall, but when they were self-pollinated they produced second generation, or F 2 , progeny three-quarters of which were tall and one-quarter dwarf. The dwarfall bred true, and ...
Potato Genome Sequencing Consortium: Final
... has four, often highly distinct copies of each of these genes. An important aspect of the PGSC’s work was the use of a ‘doubled monoploid’ (DM) clone of the Phureja group of potatoes which has two identical copies of each gene. This clone was made some time ago in the USA by making a ‘monoploid’ wit ...
... has four, often highly distinct copies of each of these genes. An important aspect of the PGSC’s work was the use of a ‘doubled monoploid’ (DM) clone of the Phureja group of potatoes which has two identical copies of each gene. This clone was made some time ago in the USA by making a ‘monoploid’ wit ...
Genetics - York University
... responsible for individual inheritable traits, but not what they were in any physical sense. Work on chromosomes led scientists to believe that these factors were conveyed by the chromosomes , but how was not ...
... responsible for individual inheritable traits, but not what they were in any physical sense. Work on chromosomes led scientists to believe that these factors were conveyed by the chromosomes , but how was not ...
Chromosomes in Saccharomyces cerevisiae
... telomeres, or the presence on natural chromosomes of previously unidentified specialized sequences that are required for accurate chromosome segregation. We examined the role of telomere-centromere separation by analyzing the behavior of telocentric derivatives of chromosome III. We made a full-leng ...
... telomeres, or the presence on natural chromosomes of previously unidentified specialized sequences that are required for accurate chromosome segregation. We examined the role of telomere-centromere separation by analyzing the behavior of telocentric derivatives of chromosome III. We made a full-leng ...
genetics - Liceocopernico.it
... In the next ninety years, genetics grew from virtually zero knowledge to the present day ability to exchange genetic material between a wide range of unrelated organisms. Medicine and agriculture may literally be revolutionized by these Tecent developments in molecular genetics. Some exposure to col ...
... In the next ninety years, genetics grew from virtually zero knowledge to the present day ability to exchange genetic material between a wide range of unrelated organisms. Medicine and agriculture may literally be revolutionized by these Tecent developments in molecular genetics. Some exposure to col ...
gene mapping, marker gene mapping, marker-assisted
... selective breeding, (2) genomic mapping and marker-assisted selection (MAS), (3) gene cloning and (4) transgenic fish production, all with the long-term goal to produce fish broodstocks with improved economic traits. In addition to aquaculture interest, the university has a population genetics progr ...
... selective breeding, (2) genomic mapping and marker-assisted selection (MAS), (3) gene cloning and (4) transgenic fish production, all with the long-term goal to produce fish broodstocks with improved economic traits. In addition to aquaculture interest, the university has a population genetics progr ...
Gene Mapping, Marker-Assisted Selection, Gene Cloning, Genetic
... selective breeding, (2) genomic mapping and marker-assisted selection (MAS), (3) gene cloning and (4) transgenic fish production, all with the long-term goal to produce fish broodstocks with improved economic traits. In addition to aquaculture interest, the university has a population genetics progr ...
... selective breeding, (2) genomic mapping and marker-assisted selection (MAS), (3) gene cloning and (4) transgenic fish production, all with the long-term goal to produce fish broodstocks with improved economic traits. In addition to aquaculture interest, the university has a population genetics progr ...
genetics and cytogenetics
... to them I wish to express my deepest appreciation. However, I must e~phasize that they are in no way responsible for any of the errors that may appear in the book. Professor George H. Shull of Princeton University has read and criticized the entire text in manuscript, and I am very grateful to him f ...
... to them I wish to express my deepest appreciation. However, I must e~phasize that they are in no way responsible for any of the errors that may appear in the book. Professor George H. Shull of Princeton University has read and criticized the entire text in manuscript, and I am very grateful to him f ...