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The Genetic Basis of Idiopathic Pulmonary Arterial Hypertension
The Genetic Basis of Idiopathic Pulmonary Arterial Hypertension

... 45 IPAH and non-IPAH patients. Exons I, 8, and 13 of the BMPR2 genes of these patients were re-sequenced using PCR amplification and gel purification. Exons 1, 8, and 12 were particularly chosen because of their locations in the extra celh,dar,kinase, and cytoplasmic tail portions of the BMPR2 gene, ...
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Microevolution

Microevolution is the change in allele frequencies that occur over time within a population. This change is due to four different processes: mutation, selection (natural and artificial), gene flow, and genetic drift. This change happens over a relatively short (in evolutionary terms) amount of time compared to the changes termed 'macroevolution' which is where greater differences in the population occur.Population genetics is the branch of biology that provides the mathematical structure for the study of the process of microevolution. Ecological genetics concerns itself with observing microevolution in the wild. Typically, observable instances of evolution are examples of microevolution; for example, bacterial strains that have antibiotic resistance.Microevolution over time leads to speciation or the appearance of novel structure, sometimes classified as macroevolution. Macro and microevolution describe fundamentally identical processes on different scales.
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