Chromosome Instability Mutants of Saccharomyces cerevisiae That Are Defective in Microtubule-Mediated Processes.
... (20). For each sample, the DNA content of 20,000 cells was determined with a Coulter EPICS 752 flow cytometer. Karyogamy measurement. a strains DBY3383 and DBY3384 and a strains DBY3382 and DBY3385 (see Table 1 for genotypes) were mated on filters in all four combinations as previously described (12 ...
... (20). For each sample, the DNA content of 20,000 cells was determined with a Coulter EPICS 752 flow cytometer. Karyogamy measurement. a strains DBY3383 and DBY3384 and a strains DBY3382 and DBY3385 (see Table 1 for genotypes) were mated on filters in all four combinations as previously described (12 ...
human lymphoblastoid cells. and unbalanced translocation in p53
... Human tumorigenesis is a multistep process in which multiple genetic alterations accumulate, ultimately producing the neoplastic phenotype (11, 29). These genetic alterations vary and include point mutations, gene amplifications, rearrangements, translocations, and deletions of specific genes. It ha ...
... Human tumorigenesis is a multistep process in which multiple genetic alterations accumulate, ultimately producing the neoplastic phenotype (11, 29). These genetic alterations vary and include point mutations, gene amplifications, rearrangements, translocations, and deletions of specific genes. It ha ...
27_Lecture_Presentation_PC
... – the movement of genes between bacteria by bacteriophages (viruses that infect bacteria) ...
... – the movement of genes between bacteria by bacteriophages (viruses that infect bacteria) ...
fall bellwork
... A. Meiosis produces cells without nuclei. B. Meiosis produces egg and sperm cells. C. Chromosomes divide during mitosis but not during meiosis. D. Mitosis results in cells with one half the number of chromosomes. ...
... A. Meiosis produces cells without nuclei. B. Meiosis produces egg and sperm cells. C. Chromosomes divide during mitosis but not during meiosis. D. Mitosis results in cells with one half the number of chromosomes. ...
Achiasmate meiosis in fission yeast - Journal of Cell Science
... Meiosis in fission yeast has some unusual features. Unlike most of the eukaryotes, S. pombe has no synaptonemal complexes (Bähler et al., 1993) and shows no crossover interference (Munz, 1994). Linear elements, which resemble the axial cores of other eukaryotes, have been proposed to play a role in ...
... Meiosis in fission yeast has some unusual features. Unlike most of the eukaryotes, S. pombe has no synaptonemal complexes (Bähler et al., 1993) and shows no crossover interference (Munz, 1994). Linear elements, which resemble the axial cores of other eukaryotes, have been proposed to play a role in ...
A Modified Genetic Algorithm for Matching Building Sets with the
... The value chosen for K depends on the number and separation of the buildings that will be matched from sketches. This value can have a significant impact on the performance of the algorithm. If the number of nearest neighbors is too small, it may become impossible to find the set of buildings that m ...
... The value chosen for K depends on the number and separation of the buildings that will be matched from sketches. This value can have a significant impact on the performance of the algorithm. If the number of nearest neighbors is too small, it may become impossible to find the set of buildings that m ...
Genetics—The Study of Inheritance
... How are traits passed from parents to offspring during fertilization? The flower color trait in pea plants can be used as an example. Suppose a hybrid purple-flowered pea plant (one with two different alleles for flower color) is mated with a white-flowered pea plant. What color flowers will the off ...
... How are traits passed from parents to offspring during fertilization? The flower color trait in pea plants can be used as an example. Suppose a hybrid purple-flowered pea plant (one with two different alleles for flower color) is mated with a white-flowered pea plant. What color flowers will the off ...
Sample Chapter - McGraw Hill Higher Education
... DNA molecule. When replication is complete, two double helices have been created from a single one. Each new DNA molecule consists of one strand from the original molecule and another built using that parental strand as a template. This is called semiconservative replication. Replication is a remark ...
... DNA molecule. When replication is complete, two double helices have been created from a single one. Each new DNA molecule consists of one strand from the original molecule and another built using that parental strand as a template. This is called semiconservative replication. Replication is a remark ...
Primer - Workforce Development in Stem Cell Research
... or growth). During these three phases, the cell grows by producing proteins and cytoplasmic organelles. Chromosomes are replicated only during the S phase. The genetic material in the nucleus is normally found loosely bundled in a protein coil called chromatin. At the onset of prophase (the first s ...
... or growth). During these three phases, the cell grows by producing proteins and cytoplasmic organelles. Chromosomes are replicated only during the S phase. The genetic material in the nucleus is normally found loosely bundled in a protein coil called chromatin. At the onset of prophase (the first s ...
mei-38 Is Required for Chromosome Segregation During Meiosis in
... Accepted for publication July 13, 2008 ABSTRACT Meiotic chromosome segregation occurs in Drosophila oocytes on an acentrosomal spindle, which raises interesting questions regarding spindle assembly and function. One is how to organize a bipolar spindle without microtubule organizing centers at the p ...
... Accepted for publication July 13, 2008 ABSTRACT Meiotic chromosome segregation occurs in Drosophila oocytes on an acentrosomal spindle, which raises interesting questions regarding spindle assembly and function. One is how to organize a bipolar spindle without microtubule organizing centers at the p ...
Gene mapping - Australian Mathematical Sciences Institute
... The cell is the basic structural, functional and biological unit of all living things. All organisms are composed of one or more cells and all cells come from preexisting cells. Humans contain trillions of cells. Most plant and animal cells are between 1 and 100 micrometres and therefore are visible ...
... The cell is the basic structural, functional and biological unit of all living things. All organisms are composed of one or more cells and all cells come from preexisting cells. Humans contain trillions of cells. Most plant and animal cells are between 1 and 100 micrometres and therefore are visible ...
The evolutionary history of human chromosome 7
... regions at 7q22 and 7p22 in African apes, but not in the homologous chromosome regions in orangutan and gibbon. Since a detailed analysis of the WBS orthologous region on mouse chromosome 5 provided no evidence of duplicated segments, the authors concluded that these segmental duplications are of re ...
... regions at 7q22 and 7p22 in African apes, but not in the homologous chromosome regions in orangutan and gibbon. Since a detailed analysis of the WBS orthologous region on mouse chromosome 5 provided no evidence of duplicated segments, the authors concluded that these segmental duplications are of re ...
Chromatin folding – from biology to polymer models - UvA-DARE
... within a 10 kb range are averaged. In the analysis of large-scale chromatin folding such an approach is justified as long as the monomer size is larger than the persistence length Lp of the chromatin fibre, i.e. the length over which the fibre is stiff (Box 1). It should be noted that the precise va ...
... within a 10 kb range are averaged. In the analysis of large-scale chromatin folding such an approach is justified as long as the monomer size is larger than the persistence length Lp of the chromatin fibre, i.e. the length over which the fibre is stiff (Box 1). It should be noted that the precise va ...
Array Flip Book
... • Autism or unexplained autisitic features • Seizures A patient with any of the above and/or a normal karyotype/FISH studies To confirm and further characterize abnormal cytogenetic results ...
... • Autism or unexplained autisitic features • Seizures A patient with any of the above and/or a normal karyotype/FISH studies To confirm and further characterize abnormal cytogenetic results ...
V Sem Zoology MUTATIONS
... a) Mutations that are in the somatic tissues of the body b) Mutations are NOT transmitted to progeny c) The extent of the phenotypic effect depends upon whether the mutation is dominant or recessive (dominant mutations generally have a greater effect) d) The extent of the phenotypic effect depends u ...
... a) Mutations that are in the somatic tissues of the body b) Mutations are NOT transmitted to progeny c) The extent of the phenotypic effect depends upon whether the mutation is dominant or recessive (dominant mutations generally have a greater effect) d) The extent of the phenotypic effect depends u ...
Genetics
... Genes can be as short as 1000 base pairs or as long as several hundred thousand base pairs. It can even be carried by more than one chromosome. The estimate for the number of genes in humans has decreased as our knowledge has increased. As of 2001, humans are thought to have between 30,000 and 40,00 ...
... Genes can be as short as 1000 base pairs or as long as several hundred thousand base pairs. It can even be carried by more than one chromosome. The estimate for the number of genes in humans has decreased as our knowledge has increased. As of 2001, humans are thought to have between 30,000 and 40,00 ...
Answers to test 1
... in mice using the chemical mutagen, EMS. She then attempts to determine whether each mutant shows segregation consistent with single gene ratios by carrying out the appropriate set of crosses. This process above is best described as: a) Northern blotting b) Meiosis c) Reverse genetics (in reverse yo ...
... in mice using the chemical mutagen, EMS. She then attempts to determine whether each mutant shows segregation consistent with single gene ratios by carrying out the appropriate set of crosses. This process above is best described as: a) Northern blotting b) Meiosis c) Reverse genetics (in reverse yo ...
Translocation Breakpoints Are Clustered on Both Chromosome 8
... HE t(8;2 l)(q22;q22) is a balanced reciprocal translocation associated with about 6% of all cases of acute myeloid leukemia (AML). Up to 92% of cases with this translocation are classified as French-American-British (FAB) subtype M2, and they have distinctive clinical and morphologic features. ',* T ...
... HE t(8;2 l)(q22;q22) is a balanced reciprocal translocation associated with about 6% of all cases of acute myeloid leukemia (AML). Up to 92% of cases with this translocation are classified as French-American-British (FAB) subtype M2, and they have distinctive clinical and morphologic features. ',* T ...
Molecular tools for breeding basidiomycetes
... conditions. True diploidy occurs at the basidia where karyogamy takes place immediately before the onset of the meiosis giving rise to four uninucleate basidiospores. At this diploid stage, genetic recombination can occur, although some reports have also suggested the occurrence of parasexual somati ...
... conditions. True diploidy occurs at the basidia where karyogamy takes place immediately before the onset of the meiosis giving rise to four uninucleate basidiospores. At this diploid stage, genetic recombination can occur, although some reports have also suggested the occurrence of parasexual somati ...
grade: / 125
... Creutzfeldt-‐Jakob and famililal fata insomnia: get one disease or the other depending on which polymorphism they have at codon 129 (have same mutation at codon 128) Modifier genes of disease expression, ...
... Creutzfeldt-‐Jakob and famililal fata insomnia: get one disease or the other depending on which polymorphism they have at codon 129 (have same mutation at codon 128) Modifier genes of disease expression, ...
Chapter 7 Notes: DNA Profiling
... • DNA is negatively charged, so drawn toward positive pole (anode) when placed in an electric field • Matrix of gel acts as a molecular sieve through which smaller DNA fragments can move more easily than larger ones • Smaller fragments (fewer base pairs) move more quickly than larger ones (more base ...
... • DNA is negatively charged, so drawn toward positive pole (anode) when placed in an electric field • Matrix of gel acts as a molecular sieve through which smaller DNA fragments can move more easily than larger ones • Smaller fragments (fewer base pairs) move more quickly than larger ones (more base ...
- NRC Research Press
... blocks using a deletion mapping approach. All three chromosomes, 5A, 5B, and 5D, were shown to have a similar structure, apart from the 4A–5A translocation on the distal end of chromosome arm 5AL. The physical mapping of rice markers on the deletion lines revealed that the whole of rice chromosome 9 ...
... blocks using a deletion mapping approach. All three chromosomes, 5A, 5B, and 5D, were shown to have a similar structure, apart from the 4A–5A translocation on the distal end of chromosome arm 5AL. The physical mapping of rice markers on the deletion lines revealed that the whole of rice chromosome 9 ...
F plasmid
... some species form colonies • Most prokaryotic cells are 0.5–5 µm, much smaller than the 10–100 µm of many eukaryotic cells • Prokaryotic cells have a variety of shapes • The three most common shapes are spheres (cocci), rods (bacilli), and spirals Copyright © 2008 Pearson Education, Inc., publishing ...
... some species form colonies • Most prokaryotic cells are 0.5–5 µm, much smaller than the 10–100 µm of many eukaryotic cells • Prokaryotic cells have a variety of shapes • The three most common shapes are spheres (cocci), rods (bacilli), and spirals Copyright © 2008 Pearson Education, Inc., publishing ...
Chromosome
A chromosome (chromo- + -some) is a packaged and organized structure containing most of the DNA of a living organism. It is not usually found on its own, but rather is complexed with many structural proteins called histones as well as associated transcription (copying of genetic sequences) factors and several other macromolecules. Two ""sister"" chromatids (half a chromosome) join together at a protein junction called a centromere. Chromosomes are normally visible under a light microscope only when the cell is undergoing mitosis. Even then, the full chromosome containing both joined sister chromatids becomes visible only during a sequence of mitosis known as metaphase (when chromosomes align together, attached to the mitotic spindle and prepare to divide). This DNA and its associated proteins and macromolecules is collectively known as chromatin, which is further packaged along with its associated molecules into a discrete structure called a nucleosome. Chromatin is present in most cells, with a few exceptions - erythrocytes for example. Occurring only in the nucleus of eukaryotic cells, chromatin composes the vast majority of all DNA, except for a small amount inherited maternally which is found in mitochondria. In prokaryotic cells, chromatin occurs free-floating in cytoplasm, as these cells lack organelles and a defined nucleus. The main information-carrying macromolecule is a single piece of coiled double-stranded DNA, containing many genes, regulatory elements and other noncoding DNA. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions. Chromosomes vary widely between different organisms. Some species such as certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm which contain cellular DNA and play a role in horizontal gene transfer.Compaction of the duplicated chromosomes during cell division (mitosis or meiosis) results either in a four-arm structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends. Chromosomal recombination during meiosis and subsequent sexual reproduction plays a vital role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe and die, or it may unexpectedly evade apoptosis leading to the progression of cancer.In prokaryotes (see nucleoids) and viruses, the DNA is often densely packed and organized. In the case of archaea by homologs to eukaryotic histones, in the case of bacteria by histone-like proteins. Small circular genomes called plasmids are often found in bacteria and also in mitochondria and chloroplasts, reflecting their bacterial origins.