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Construction of a set of convenient saccharomyces cerevisiae
Construction of a set of convenient saccharomyces cerevisiae

... replacement. For each marker, we determined that for the European Union Yeast Genome Sequencthe auxotrophy segregated 2 : 2 in tetrads (data not ing Programme. This DNA has been or is curshown) and confirmed the gene replacement by rently being used for sequencing chromosomes Southern analysis (data ...
Chromosomal G + C Content Evolution in Yeasts
Chromosomal G + C Content Evolution in Yeasts

... reduced. We propose that these GC-poor troughs indicate the positions of centromeres because in Y. lipolytica they coincide with the five experimentally identified centromeres. In P. stipitis, the troughs contain clusters of the retrotransposon Tps5. Likewise, in Debaryomyces hansenii, there is one ...
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Mendelian Genetics and Beyond Chapter 4 Study Prompts 1. What is a

... 1. A mode of inheritance is a pattern in which traits are inherited from one generation to the next. 2. Definitions: a. Autosomal dominant is a trait that is on one of the 22 autosomal chromosomes and will mask another trait. These traits are evident in every generation. b. Autosomal recessive is a ...
here
here

... 2. Hitchhikers Thumb- a straight thumb seems to be dominant over a bent one. The letter T is used to express the dominant allele (straight thumb), a lowercase (t) for Hitchhikers thumb allele. 3. Dimpled chin- a distinct depression or dimple in the chin results from a dominant allele (D). 4. Rolling ...
Genetics Trivia Review
Genetics Trivia Review

Mendelian Genetics
Mendelian Genetics

... recombination for any 2 genes located on different chromosomes due to independent assortment of metaphase I Linked Genes – freq of recombination varies depending on distance between linked genes due to crossing over during prophase I Using the freq of recombination can construct a genetic map (order ...
Cockatiel Genetics
Cockatiel Genetics

... caution about averages is in order at this point. The above expectations are only accurate for a large sampling. One clutch of four young could be far from the calculated average. If silver or fallow is substituted for pied in all the foregoing matings. the results are exactly the same. Now let's ha ...
genetics: typical test questions
genetics: typical test questions

... produced that are smaller but identical to the parent cell. In mitosis/meiosis, the haploid /diploid parent cell undergoes a process in which one /two / four cells are produced that are not identical to the parent cell. Fill in the blanks: 2. Humans have ___________ ___________of chromosomes, ______ ...
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...  Xist RNA may cause replication origins to fire late, resulting in heterochromatin formation  modulate histone acetetylation – The Drosophila mof gene is required for dosage compensation and is an acetyltransferase ...
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... DMs are numerous paired minute chromatin bodies that were often detected among 4#,6-diamidino-2-phenylindole- or Giemsa-stained metaphase chromosome spreads prepared from human cancer cells (for recent review, see refs 1,2). The DMs appear in various kinds of human cancer cells but not in normal cel ...
Research Update Winter 2003/2004
Research Update Winter 2003/2004

... standard trisomy 21 Down syndrome) or it can be an extra 21 attached to another chromosome (translocation Down syndrome). First of all, there is no known difference in the physical and developmental outcome between individuals with standard trisomy 21 and those with the much less common translocatio ...
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Prentice Hall Biology

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... • Nondisjunction: Failure of paired chromosomes to separate (to disjoin) during cell division, so that both chromosomes go to one daughter cell and none go to the other. Nondisjunction causes errors in chromosome number, such as trisomy 21 (Down syndrome) and monosomy X (Turner syndrome). It is also ...
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supplementary materials

... unviable embryo, and the w2 locus on chromosome arm 10L which results in a mutant kernels in a purple kernel stock displaying a mottled purple aleurone phenotype, and producing albino seedlings. Both anl1 and w2 are distal to the more commonly used a2 and r1 loci on chromosome arms 5S and 10L, resp ...
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A GENETIC EXPLANATION OF HOW GPRA IS INHERITED

letter Widespread aneuploidy revealed by DNA microarray expression profiling
letter Widespread aneuploidy revealed by DNA microarray expression profiling

... a function of its chromosomal location, we noted an expres- Fig. 3 Selection for aneuploidy in rnr1∆ and rps24a∆/rps24a∆ mutants. a, Slow-growing rnr1∆ (sector 2) or sion bias in a 56-ORF region on rps24a∆/rps24a∆ (sector 4) cells or their isogenic parental wild-type cells (sectors 1 and 3) were str ...
Exam 2 (pdf - 90.37kb)
Exam 2 (pdf - 90.37kb)

... • Write your student number in the space provided above on this page. • Check that your name and student number as printed on your answer sheet for multiple-choice questions are correct, and sign your name in the space provided to verify this. • All written responses must be in English. At the end o ...
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Genetics Jeopardy

... A) Your DNA B) Your Genotype C) Your Environment D) Both DNA and Environment ...
Biology Final Exam Review
Biology Final Exam Review

... 10. The difference between an ecosystem and a community is that a(an) a) community includes both living and nonliving parts of the environment. b) community includes both natural and artificial parts of the environment. c) ecosystem includes both living and nonliving parts of the environment. d) eco ...
Bio 102 Practice Problems Chromosomes, Karyotyping and Sex
Bio 102 Practice Problems Chromosomes, Karyotyping and Sex

A small region on the X chromosome of Drosophila regulates a key
A small region on the X chromosome of Drosophila regulates a key

... deleted (Dobzhansky and Schultz, 1934; Pipkin, 1940). These results suggested a purely quantitative effect achieved by many female determining factors scattered along the X chromosome. Attempts to localize major female determining genes in diploid animals failed. When small duplications of various r ...
Bioreg2017_Replication3_V4
Bioreg2017_Replication3_V4

... Hence, you plan on identifying the gene that encodes the protein and mutagenizing the gene in cells where you can functionally assay the sequence element However, before you take all the effort to clone the gene and do the reverse genetics, you want some indication that this binding protein is proba ...
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1 Characteristics of Life

... scientist Robert Hooke invented a basic light microscope and observed cells for the first time, by looking at a piece of cork. You may use light microscopes in the classroom. You can use a light microscope to see cells (Figure 3.1). But many structures in the cell are too small to see with a light m ...
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Chromosome



A chromosome (chromo- + -some) is a packaged and organized structure containing most of the DNA of a living organism. It is not usually found on its own, but rather is complexed with many structural proteins called histones as well as associated transcription (copying of genetic sequences) factors and several other macromolecules. Two ""sister"" chromatids (half a chromosome) join together at a protein junction called a centromere. Chromosomes are normally visible under a light microscope only when the cell is undergoing mitosis. Even then, the full chromosome containing both joined sister chromatids becomes visible only during a sequence of mitosis known as metaphase (when chromosomes align together, attached to the mitotic spindle and prepare to divide). This DNA and its associated proteins and macromolecules is collectively known as chromatin, which is further packaged along with its associated molecules into a discrete structure called a nucleosome. Chromatin is present in most cells, with a few exceptions - erythrocytes for example. Occurring only in the nucleus of eukaryotic cells, chromatin composes the vast majority of all DNA, except for a small amount inherited maternally which is found in mitochondria. In prokaryotic cells, chromatin occurs free-floating in cytoplasm, as these cells lack organelles and a defined nucleus. The main information-carrying macromolecule is a single piece of coiled double-stranded DNA, containing many genes, regulatory elements and other noncoding DNA. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions. Chromosomes vary widely between different organisms. Some species such as certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm which contain cellular DNA and play a role in horizontal gene transfer.Compaction of the duplicated chromosomes during cell division (mitosis or meiosis) results either in a four-arm structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends. Chromosomal recombination during meiosis and subsequent sexual reproduction plays a vital role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe and die, or it may unexpectedly evade apoptosis leading to the progression of cancer.In prokaryotes (see nucleoids) and viruses, the DNA is often densely packed and organized. In the case of archaea by homologs to eukaryotic histones, in the case of bacteria by histone-like proteins. Small circular genomes called plasmids are often found in bacteria and also in mitochondria and chloroplasts, reflecting their bacterial origins.
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