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Genetic Engineering: How and why scientists manipulate DNA in
Genetic Engineering: How and why scientists manipulate DNA in

... Insert spider genes into cells of lactating goats – manufacture silk along with milk = light, tough, flexible material  military uniforms, medical sutures  30% of US milk produced by genetically modified (GM) cows  Pigs GM to produce high levels of lean meat ...
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... zygote, syngamy. Be able to label a diagram of the different phases - refer to your text. Know the different phases of meiosis and how they are different from mitosis? What are the sexual sources for variation? How does meiosis contribute to genetic variation?What is nondisjunction?Polyploidy? Aneup ...
Exam 3 Material Outline MS Word
Exam 3 Material Outline MS Word

... 1) What it is that one generation passes on so that the next generation can be formed. 2) What controls the development of a living thing as it goes from being a microscopic cell to a larger organism. 3) How it is that the adult body is able to build muscle or repair a wound. I. The Role of DNA in C ...
Slide 1
Slide 1

... You inherit traits through sexual reproduction. During sexual reproduction, a cell containing genetic material (DNA) from the mother and a cell containing genetic material (DNA) from the father combine into a completely new cell, which becomes the offspring. ...
GRADE 11F: Biology 4
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Slide 1

... • Genetic mapping: linkage map determined by recombination frequencies – Currently have 500 markers on human genome • Physical mapping: map units • DNA sequencing: list of bases for all 3million nucleotides pairs ...
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Word - Delaware Department of Education

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... and deletions can alter a gene so that its message is no longer correctly parsed. These changes are called frameshifts. For example, consider the sentence, "The fat cat sat." Each word represents a codon. If we delete the first letter and parse the sentence in the same way, it doesn't make sense. In ...
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12.1 - DNA History / Discovery

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Blueprint of Life

... —a complete set of chromosomes (that is, chromosomes in pairs) is needed for normal development —the inheritance 'factors' are found on chromosomes within the nucleus—that is, chromosomes are the carriers of heredity. Sutton and grasshoppers Walter Sutton (1877-1916), an American cytologist, studied ...
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Chromosome



A chromosome (chromo- + -some) is a packaged and organized structure containing most of the DNA of a living organism. It is not usually found on its own, but rather is complexed with many structural proteins called histones as well as associated transcription (copying of genetic sequences) factors and several other macromolecules. Two ""sister"" chromatids (half a chromosome) join together at a protein junction called a centromere. Chromosomes are normally visible under a light microscope only when the cell is undergoing mitosis. Even then, the full chromosome containing both joined sister chromatids becomes visible only during a sequence of mitosis known as metaphase (when chromosomes align together, attached to the mitotic spindle and prepare to divide). This DNA and its associated proteins and macromolecules is collectively known as chromatin, which is further packaged along with its associated molecules into a discrete structure called a nucleosome. Chromatin is present in most cells, with a few exceptions - erythrocytes for example. Occurring only in the nucleus of eukaryotic cells, chromatin composes the vast majority of all DNA, except for a small amount inherited maternally which is found in mitochondria. In prokaryotic cells, chromatin occurs free-floating in cytoplasm, as these cells lack organelles and a defined nucleus. The main information-carrying macromolecule is a single piece of coiled double-stranded DNA, containing many genes, regulatory elements and other noncoding DNA. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions. Chromosomes vary widely between different organisms. Some species such as certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm which contain cellular DNA and play a role in horizontal gene transfer.Compaction of the duplicated chromosomes during cell division (mitosis or meiosis) results either in a four-arm structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends. Chromosomal recombination during meiosis and subsequent sexual reproduction plays a vital role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe and die, or it may unexpectedly evade apoptosis leading to the progression of cancer.In prokaryotes (see nucleoids) and viruses, the DNA is often densely packed and organized. In the case of archaea by homologs to eukaryotic histones, in the case of bacteria by histone-like proteins. Small circular genomes called plasmids are often found in bacteria and also in mitochondria and chloroplasts, reflecting their bacterial origins.
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