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Genetics Principles And Analysis
Genetics Principles And Analysis

... Genetics: Principles and analysis / Daniel L. Hartl, Elizabeth W. Jones.—4th ed. p. cm. Includes bibliographical references (p.). ISBN 0-7637-0489-X 1. Genetics. I. Jones, Elizabeth W. II. Title. QH430.H3733 1998 576.5—dc21 ...
Translation of Drug Metabolic Enzyme and Transporter (DMET) Genetic Variants into Star Allele Notation using SAS.
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... The cytochrome P450 superfamily of enzymes (CYPs), together with other enzyme classes and transport proteins have important roles in the uptake, distribution, metabolism and excretion of a host of therapeutic drugs and other xenobiotic molecules (Lewis (2005) and Cascorbi (2006)). Extensive literatu ...
Recombination in large RNA viruses: Coronaviruses
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... The effects of recombination on the evolution of coronavirus DI RNAs have also been demonstrated.25,28,29 Furthermore, in natural coronavirus infections, recombination also serves as an evolutionary tool. This is particularly evident for IBV, many field isolates of which are recombinants between var ...
A gain of function mutation causing skeletal overgrowth in the
A gain of function mutation causing skeletal overgrowth in the

... (rpz, rpz2 and rpz3). Two additional paralogues (rpz4 and rpz5) are also present on chromosome 16, outside of the critical region. All five genes are located on the same strand. Marker positions are shown along with their number of crossovers from rapunzel (see Supplemental data for more details rega ...
The Complex Inheritance of Maize Domestication Traits and Gene
The Complex Inheritance of Maize Domestication Traits and Gene

... was given to shepherd them to completion. Every day and conversation I have had with John as my advisor has made me into a better scientist and I am extremely thankful for the opportunity I was given six years ago when I joined the Doebley lab. I have been fortunate enough to also work in an outstan ...
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Genetic studies of psoriasis and psoriatic arthritis
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... occupational aspects. Psoriasis patients suffer impaired quality of life similar to or worse than patients with other chronic diseases such as ischemic heart disease and diabetes (Finlay et al. 1987). Over the past 20 years, our understanding of the disease mechanisms has advanced significantly and ...
org.Dr.eg.db
org.Dr.eg.db

... Whenever any of these mappings are cast as a data.frame, all the results will be output in an appropriate tabular form. Mappings between entrez gene identifiers and GO information were obtained through their mappings to Entrez Gene identifiers. NAs are assigned to entrez gene identifiers that can no ...
Transcriptional Attenuation
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... phenomenon that reduces the extent or rate of transcription. In studies of bacterial gene regulation, however, it has acquired a more restricted definition and is used to describe a mechanism in which the level of transcriptional termination at a single, specific site within an operon, called an att ...
Complex inheritance of larval adaptation in Plutella
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... the glucosinolate–myrosinase defense system toxic to most herbivores but harmless to P. xylostella larvae that circumvent this defense system with a specific enzyme, glucosinolate sulfatase (Ratzka et al., 2002). Owing to the success of this detoxicative strategy, DBM is a major pest of cultivated c ...
Baker, B. S., Hoff, G., Kaufman, T. C., Wolfner, M. W., and Hazelrigg, T. (1991). A cytopgenetic analysis of the doublesex locus and its flanking regions. Genetics 127: 125-138.
Baker, B. S., Hoff, G., Kaufman, T. C., Wolfner, M. W., and Hazelrigg, T. (1991). A cytopgenetic analysis of the doublesex locus and its flanking regions. Genetics 127: 125-138.

... into the male-specific dsx mRNA (R.N. NAGOSHI and B. S. BAKER, in preparation). Surprisingly, when dsxD is heterozygous with a wild type dsx allele in a chromosomally female individual, and thus both the malespecific and female-specific dsx mRNAs are being produced (R. N. NAGOSHIand B. S. BAKER, in ...
Persistence and Loss of Meiotic Recombination
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... allele or even to slow its rate of loss. The model, however, assumed an infinitely large population, whereas many of the benefits of genetic recombination are thought to derive from the stochastic nature of events in small populations (Otto and Barton 2001). The model also considered only chromosome ...
chicken.db - Bioconductor
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Using Genetic Algorithms with Asexual Transposition
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... certain genetic elements in corn occasionally move producing kernels with unusual colors that could not have resulted from crossover or mutation. Transposons were for a long time considered as some sort of abnormality, but in 1983, when she was awarded the Nobel Prize, many such transposons had been ...
Warren, ST and Ashley, CT: Triplet repeat expansion mutations: The example of fragile X syndrome. Annual Review of Neuroscience 18:77-99 (1995).
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... single restriction fragment of approximately 5 kb that contained both the proximal and distal fragile X hybrid breakpoints and also detected length variation in fragile X patients on Southern blots. Kremer et al ( 199 1a) further localized this instability to a single 1.0-kb Pst I fragment, pfxa2, t ...
attached / unattached earlobes
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... X to her. It is for that reason that males are more commonly affected by sex-X-linked conditions than females. ...
Genetics of asthma and atopy Koppelman, Gerard
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... 2003 - Essential Completion = 30, 000 – 40,000 genes ?? = 24, 195 genes !!!??? ...
Apical-basal pattern formation in the Arabidopsis
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... asymmetric division of the zygote, we have performed a detailed genetic and phenotypic analysis of the gnom gene to determine its role in apical-basal pattern formation. Our results suggest that the gnom gene very likely acts before the asymmetric division of the zygote when apical-basal polarity fi ...
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... Autores: Khokhlov,R. YU.; Kuznetcov,S. I. The authors have used non-laying and laying hens (Lohmann Brown), in order to study morphological aspects development of tunica mucosa of the oviduct. The results showed that the oviduct of the hen is well-developed at the left side, atrophied at the right s ...
Pitx1 and Pitx2 are required for development of hindlimb buds
Pitx1 and Pitx2 are required for development of hindlimb buds

... the hypothesis of a partial redundancy between these two Pitx genes. In order to ascertain the putative redundancy between Pitx1 and Pitx2 genes, Pitx1+/– mice were crossed with mice carrying either a hypomorphic (neo) or null allele of the Pitx2 gene (Fig. 1A) (Gage et al., 1999). To obtain double ...
SPATULA, a bHLH carpel development gene
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... and pollen tract tissues throughout their development confirming its role in regulating their growth. It is also expressed in many other tissues where it may act redundantly to control growth, including the peripheral zone of the shoot apical meristem, and specific tissues within leaves, petals, sta ...
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THE GENETICS AND REPRODUCTIVE ISOLATING MECHANISMS
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... could be noticed. On the contrary the homozygous BB individuals which appeared first in the 10th generation were obviously darker and had broader vein markings than the mother. This is also proof that the mother was, in spite of her high-alpine origin, heterozygous. In spite of the well-proven monoh ...
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X-inactivation



X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.
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