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Heredity and Development: Second Edition
Heredity and Development: Second Edition

... manner: First, we assume that the hypothesis is correct and then make certain deductions. These deductions can be tested to see if they are true or false. Morgan made four such deductions and found that the predicted results were always obtained. The more deductions that are verified, the more likel ...
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enzymes,  only  a  few  appear ... Angelman syndrome to a single gene like
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X-inactivation



X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.
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