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Development of Co-Dominant Amplified Polymorphic Sequence
Development of Co-Dominant Amplified Polymorphic Sequence

... restriction enzymes were used for each marker. From each parent, PCR amplification product (15 µl) was digested in a 40-µl total reaction volume for 3 h at the manufacturer’s specified temperature and buffer conditions. Digestion products were separated via electrophoresis in a 1.5% agarose gel in T ...
PDF
PDF

... heterogeneous surface receptors collectively referred to as PfEMP1. These proteins are encoded by a large, polymorphic gene family called var. The family contains approximately 60 individual genes, which are subject to strict, mutually exclusive expression, with the single expressed var gene determi ...
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Correction to “Frequency of Undetected CYP2D6
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Chapter 13
Chapter 13

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Development of novel computational tools based on
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... complex combination of genetic and environmental factors (Schultz et al. 2005). Mutant mice are important tools for identifying these factors, their function in the auditory system, and the pathogenesis of hearing loss (Haider et al. 2002). For example, studies of polygenic age-related hearing loss ...
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Selective Crossover in Genetic Algorithms: An Empirical Study
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Chapter 13 - Meiosis and Sexual Life Cycles

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Nosology of Deafness - American Academy of Audiology
Nosology of Deafness - American Academy of Audiology

... same as the chance of inheriting a particular chromosome of the pair: 50 per cent . A single mutant gene is recessive (1) if it causes no evident abnormality, the function being well covered by the normal partner gene (allele) . Such an individual may be referred to as a heterozygous carrier. When b ...
PDF
PDF

... We define ‘repeat-masked sequences’ as those in which known famWe scanned a 15-kb region upstream of each gene and localilies of repeats were masked by the computer program Repeat- ized putative first exons and promoter regions using FirstEF preMasker (http://ftp.genome.washington.edu). We aligned t ...
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... So far, we have focused on chromatin structure at the level of the 30 nm chromatin fibre, largely because this is the only level of higher‑order chromatin structure that we have reasonable models for. However, it is clear from electron microscopy studies that a lot of mammalian chromatin is packaged ...
Saccharomycopsis fibuligera and Yarrowia lipol`ica
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... were demonstrated and it was established that four distinct types consistent with their specific positions in the pedigree chart could be clearly distinguished. Furthermore, by a study of the patterns of hybridization signals for specific genes of S. fibuligera for an intergeneric hybrid and i t s m ...
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X-inactivation



X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.
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