Maternal-Effect Genes That Alter the Fate Map of the Drosophila
... have been studied. Each of the maternal-effect mutations alters both the normal pattern of ftx protein expression and proper segmental development. No single mutation or any combination of mutations causes a complete repression or derepression of ftx protein expression; we have not observed in any c ...
... have been studied. Each of the maternal-effect mutations alters both the normal pattern of ftx protein expression and proper segmental development. No single mutation or any combination of mutations causes a complete repression or derepression of ftx protein expression; we have not observed in any c ...
twin studies - Institute for Behavioral Genetics
... Initial explanations of ‘congenital word-blindness’ held that significant defects in the visual system were solely responsible for the letter and word reversals that were believed to epitomize dyslexic reading. This viewpoint turned out to be untenable. Although subtle abnormalities in specific aspe ...
... Initial explanations of ‘congenital word-blindness’ held that significant defects in the visual system were solely responsible for the letter and word reversals that were believed to epitomize dyslexic reading. This viewpoint turned out to be untenable. Although subtle abnormalities in specific aspe ...
Mutants of the Drosophila ncd microtubule motor
... embryos of the null mutant (Sturtevant, 1929; Lewis and Gencarella, 1952). The effects of ncd on chromosome segregation in meiosis and mitosis are separated by the mutant, ncdD. Oocytes of ncdD/ncdD females exhibit defective meiotic chromosome segregation, but embryos of ncdD/ncdD females are near w ...
... embryos of the null mutant (Sturtevant, 1929; Lewis and Gencarella, 1952). The effects of ncd on chromosome segregation in meiosis and mitosis are separated by the mutant, ncdD. Oocytes of ncdD/ncdD females exhibit defective meiotic chromosome segregation, but embryos of ncdD/ncdD females are near w ...
Additional data file 9
... previously uncharacterized TFs that are expressed in the embryonic CNS, as well as 87 other TFs with no previous characterization of the embryonic CNS spatial expression. CG9817 (zf-C2H2), CG4328 (Homeobox), and CG11093 (Ski-Sno domain), are expressed in the brain and ventral nerve cord, and RNA-seq ...
... previously uncharacterized TFs that are expressed in the embryonic CNS, as well as 87 other TFs with no previous characterization of the embryonic CNS spatial expression. CG9817 (zf-C2H2), CG4328 (Homeobox), and CG11093 (Ski-Sno domain), are expressed in the brain and ventral nerve cord, and RNA-seq ...
The Isolation of Mutagen-Sensitive nuv Mutants of
... homozygous wild-type diploids with that of diploids heterozygous and homozygous for each nuv mutation. As before, to make direct comparisons between the different nuv diploids, the determinations were carried out as two large experiments, one for sensitivity to M N N G and the other for sensitivity ...
... homozygous wild-type diploids with that of diploids heterozygous and homozygous for each nuv mutation. As before, to make direct comparisons between the different nuv diploids, the determinations were carried out as two large experiments, one for sensitivity to M N N G and the other for sensitivity ...
Class17 1-31 Win16 Cell Cycle Notes
... Challenge: Imagine that a new strain of E. coli is found that regulates lac operon expression based on levels of mercury in the environment. Design molecular interactions (or new molecules) such that E. coli only produces high levels of lac operon products in low mercury. Why does it make sense that ...
... Challenge: Imagine that a new strain of E. coli is found that regulates lac operon expression based on levels of mercury in the environment. Design molecular interactions (or new molecules) such that E. coli only produces high levels of lac operon products in low mercury. Why does it make sense that ...
Chapter 11 - Genetics & Meiosis Review Questions (w/...
... 34. A pea plant heterozygous for height and seed color (TtYy) is crossed with a pea plant heterozygous for height but homozygous recessive for seed color (Ttyy). If 80 offspring are produced, how many are expected to be tall and have yellow seeds? 35. What might happen if the gametes of a species ha ...
... 34. A pea plant heterozygous for height and seed color (TtYy) is crossed with a pea plant heterozygous for height but homozygous recessive for seed color (Ttyy). If 80 offspring are produced, how many are expected to be tall and have yellow seeds? 35. What might happen if the gametes of a species ha ...
Epigenetic mechanisms regulate placental c-myc
... (Gomez et al., 2012) and in the cellular replicative life span (Nakamura and Cech, 1998) and is generally repressed in most adult human somatic cells, limiting their proliferative potential due to induced chromosomal instability, leading to cellular senescence after a few cell divisions. However, st ...
... (Gomez et al., 2012) and in the cellular replicative life span (Nakamura and Cech, 1998) and is generally repressed in most adult human somatic cells, limiting their proliferative potential due to induced chromosomal instability, leading to cellular senescence after a few cell divisions. However, st ...
Pisum Genetics Volume 24 1992 Research Reports
... In broad terms, five patterns of branching could be discerned among the mutants and their initial lines: complete absence of branches (N = no branches), branches from all, or almost all, vegetative nodes (C = complete), branches from the upper nodes only (A = aerial), branches from the basal nodes o ...
... In broad terms, five patterns of branching could be discerned among the mutants and their initial lines: complete absence of branches (N = no branches), branches from all, or almost all, vegetative nodes (C = complete), branches from the upper nodes only (A = aerial), branches from the basal nodes o ...
Molecular Design of Expression Systems
... upon interaction with a corresponding specific repressor protein. This interaction may be influenced by adjusting the temperature (ts regulatory mutant) or the composition (inducer or corepressor concentration) of the growth medium in order to switch from low to high promoter activity. Limitations o ...
... upon interaction with a corresponding specific repressor protein. This interaction may be influenced by adjusting the temperature (ts regulatory mutant) or the composition (inducer or corepressor concentration) of the growth medium in order to switch from low to high promoter activity. Limitations o ...
MAGMA manual (version 1.05)
... MAGMA detects a header in the file it will look for SNP IDs and p-values in the SNP and P column respectively. If no header is found it will use the first column for SNP IDs and the second column for p-values. If you want to use different columns instead, you can add the use modifier (with two value ...
... MAGMA detects a header in the file it will look for SNP IDs and p-values in the SNP and P column respectively. If no header is found it will use the first column for SNP IDs and the second column for p-values. If you want to use different columns instead, you can add the use modifier (with two value ...
Targeted gene expression as a means of altering cell fates and
... 1. pUAST: we constructed a vector into which genes can be subcloned behind the GAL UAS. A fragment containing five optimized GAL4 binding sites (the ‘ScaI site’ 17-mer; Webster et al., 1988) and a synthetic TATA box (Lillie and Green, 1989) separated by a unique NotI site from the SV40 terminator wa ...
... 1. pUAST: we constructed a vector into which genes can be subcloned behind the GAL UAS. A fragment containing five optimized GAL4 binding sites (the ‘ScaI site’ 17-mer; Webster et al., 1988) and a synthetic TATA box (Lillie and Green, 1989) separated by a unique NotI site from the SV40 terminator wa ...
Identification of Genes Needed for Regeneration, Stem Cell
... Alvarado and Newmark, 1999; data not shown). Nonetheless, since it is impractical to monitor protein levels for the products of each gene in an RNAi screen, some phenotypes resulting from dsRNA treatment could reflect incomplete gene loss of function. The RNAi by feeding methodology used for our scr ...
... Alvarado and Newmark, 1999; data not shown). Nonetheless, since it is impractical to monitor protein levels for the products of each gene in an RNAi screen, some phenotypes resulting from dsRNA treatment could reflect incomplete gene loss of function. The RNAi by feeding methodology used for our scr ...
Mapping the genes that made maize
... teosinte ears. They suggested that each of the four chromosomal segments contained a group of morphological genes rather than a single gene, although they presented no evidence to support this view. Mangelsdorf5 reported that these four segments probably map to chromosomes 1, 3, 4 and 9, but again:h ...
... teosinte ears. They suggested that each of the four chromosomal segments contained a group of morphological genes rather than a single gene, although they presented no evidence to support this view. Mangelsdorf5 reported that these four segments probably map to chromosomes 1, 3, 4 and 9, but again:h ...
Sex Determination: Why So Many Ways of Doing It?
... Meiotic sex likely has a single origin, which dates back to the origin of eukaryotes [144,145]). While most eukaryotes display some form of meiotic sex, many lack differentiated male and female gametes—a situation referred to as isogamy. Even with isogamy, however, mating is often not random but req ...
... Meiotic sex likely has a single origin, which dates back to the origin of eukaryotes [144,145]). While most eukaryotes display some form of meiotic sex, many lack differentiated male and female gametes—a situation referred to as isogamy. Even with isogamy, however, mating is often not random but req ...
Sex Determination: Why So Many Ways of Doing It?
... Meiotic sex likely has a single origin, which dates back to the origin of eukaryotes [144,145]). While most eukaryotes display some form of meiotic sex, many lack differentiated male and female gametes—a situation referred to as isogamy. Even with isogamy, however, mating is often not random but req ...
... Meiotic sex likely has a single origin, which dates back to the origin of eukaryotes [144,145]). While most eukaryotes display some form of meiotic sex, many lack differentiated male and female gametes—a situation referred to as isogamy. Even with isogamy, however, mating is often not random but req ...
Modeling Fragile X Syndrome Using Human Pluripotent Stem Cells
... the precise mechanism governing the silencing of FMR1 is not fully understood. In addition, it remains unclear when FMR1 gene inactivation takes place during embryo development. Previous reports related to the timing of FMR1 silencing showed that the FMR1 locus is still active at 8–10 weeks of gesta ...
... the precise mechanism governing the silencing of FMR1 is not fully understood. In addition, it remains unclear when FMR1 gene inactivation takes place during embryo development. Previous reports related to the timing of FMR1 silencing showed that the FMR1 locus is still active at 8–10 weeks of gesta ...
Extending FISH analysis of Paediatric Tumours
... Table shows the BACs selected and the probe sets for identifying Rhabdomyosarcomas and Ewing;s tumours. (a)This BAC was also labelled SpectrumOrange for use in the EWS-ERG fusion probe set. (b)These were selected for FLI1 after RP11-744N12 originally hybridised to the wrong chromosome and was FLI1 n ...
... Table shows the BACs selected and the probe sets for identifying Rhabdomyosarcomas and Ewing;s tumours. (a)This BAC was also labelled SpectrumOrange for use in the EWS-ERG fusion probe set. (b)These were selected for FLI1 after RP11-744N12 originally hybridised to the wrong chromosome and was FLI1 n ...
Results - BioMed Central
... gene expression level of H. sinensis as the internal control since other housekeeping ...
... gene expression level of H. sinensis as the internal control since other housekeeping ...
Functions of DNA methylation: islands, start sites, gene bodies and
... Does methylation silence transcription initiation? Given the observations of methylation at some repressed TSSs described above, what is the functional relationship between DNA methylation and transcription initiation? There is incontrovertible evidence that methylated CGIs at TSSs cannot initiate t ...
... Does methylation silence transcription initiation? Given the observations of methylation at some repressed TSSs described above, what is the functional relationship between DNA methylation and transcription initiation? There is incontrovertible evidence that methylated CGIs at TSSs cannot initiate t ...
Statistical analysis of simple repeats in the human genome
... Experiments on kinetics of DNA denaturation and renaturation and the analysis of DNA sequences have revealed that most of our genome is populated by DNA repeats of different length, number and degree of dispersion [1]. Long repeats in few copies are usually orthologous genes, which may contain hidde ...
... Experiments on kinetics of DNA denaturation and renaturation and the analysis of DNA sequences have revealed that most of our genome is populated by DNA repeats of different length, number and degree of dispersion [1]. Long repeats in few copies are usually orthologous genes, which may contain hidde ...
A component of calcium-activated potassium channels encoded by
... for molecular characterization of these channels. Genornic and complementary DNA clones &om the slo locus were'isolated and sequenced. The polypeptide predicted by slo is similar to voltage-activated K+ channel polypeptidesin discrete domains known to be essential for function. Thus, these results i ...
... for molecular characterization of these channels. Genornic and complementary DNA clones &om the slo locus were'isolated and sequenced. The polypeptide predicted by slo is similar to voltage-activated K+ channel polypeptidesin discrete domains known to be essential for function. Thus, these results i ...
X-inactivation
X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.