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Abstracts
Abstracts

... Amide-linked amino acid conjugates of some plant hormones are known to help regulate the level and activity of these hormones. However, our knowledge of how conjugation controls signaling has been limited because the conjugating enzymes were unknown. We have discovered an enzyme family that conjugat ...
Metabolic Engineering of Plant Secondary Metabolism
Metabolic Engineering of Plant Secondary Metabolism

... possibilities to alter secondary metabolite pathways. The next two chapters deal with the state-of-the-art of the transformation technologies: the Agrobacterium system and the particle gun. The next chapter will deal with the possibilities of producing antibodies in plants, this is potentially also ...
Analysis of two alleles of the urease gene from potato
Analysis of two alleles of the urease gene from potato

... absence of a canonical TATA box has been reported for other genes (Dynan, 1986; Ibrahim et al., 2001). Steady-state levels of urease mRNA were found to be undetectable by northern blot analysis using 30 lg of total RNA from a variety of organs (not shown), suggesting either a low level of transcript ...
Crosstalk Between Insulin and Toll-like Receptor
Crosstalk Between Insulin and Toll-like Receptor

... by pathogenic mechanisms). TLRs are one class of this receptor family. These receptors are expressed widely in CNS cells and play a role in the physiology and pathophysiology of the CNS (TLRs will be described in the succeeding sections) [17]. Purinergic Receptors These receptors are expressed on mi ...
Full-Text PDF
Full-Text PDF

... persistence and spread of a PDR Gram-negative organism could occur over five years. In the longer term, this equates to an approximate 4% annual chance of the scenario starting in a given year. This in turn suggests that the likelihood over a 20-year period is around 0.8, highlighting the urgent nee ...
Comparative Virulence of Monokaryotic and Dikaryotic Stages of
Comparative Virulence of Monokaryotic and Dikaryotic Stages of

... S1-5, P14-1, and 229 were used in this study. Each isolate was derived from a single uredinium and was increased and maintained separately on plants of susceptible bean cultivar Pinto 111. Plants were inoculated with either urediniospores or aeciospores one week after planting. The inoculation metho ...
Evolution of bopA Gene in Burkholderia: A Case of Convergent
Evolution of bopA Gene in Burkholderia: A Case of Convergent

... the gene is transferred horizontally. If a putative gene is an ancestral gene, it should retain a similar nucleotide composition as the rest of the genome. Similarly, exogenous gene by HGT could be detected by a significant difference of nucleotide composition to whole genome. To confirm whether bop ...
Antibiotic-resistant E. coli on supermarket meat – a serious threat to
Antibiotic-resistant E. coli on supermarket meat – a serious threat to

... second most common infections (after respiratory infections), affecting up to 15% of women each year [2], and causing an estimated 150 million cases globally per year [4]. In the UK, approximately 70-80% of all UTIs are caused by E. coli [4], and over 700,000 cases of E. coli UTIs were tested for an ...
No resistance was found to any of these antibiotics in E. coli from
No resistance was found to any of these antibiotics in E. coli from

... second most common infections (after respiratory infections), affecting up to 15% of women each year [2], and causing an estimated 150 million cases globally per year [4]. In the UK, approximately 70-80% of all UTIs are caused by E. coli [4], and over 700,000 cases of E. coli UTIs were tested for an ...
Antibacterial Honey (Medihoney™)
Antibacterial Honey (Medihoney™)

... evidence and clearly demonstrate that honey has a valuable therapeutic role to play in wound care, often where modern approaches have failed.2 There are a number of in-vitro studies that have shown the effectiveness of medical honeys on antibiotic resistant organisms, such as MRSA and P aeruginosa.5 ...
Original article A comprehensive surveillance of adamantane
Original article A comprehensive surveillance of adamantane

... AVT-10-OA-1527_Lan.indd 853 ...
Evolution and manipulation of vector host choice
Evolution and manipulation of vector host choice

... Note, that our analysis yields extreme preference strategies that may ultimately lead the pathogen  population  to extinction (figure 1).  This is because  the  current  model assumes that any  preference  strategy can evolve. Preference, however, requires an ability to discriminate between differen ...
Virulence and Pathogenicity of Fungal
Virulence and Pathogenicity of Fungal

... by inducing transcriptional and translational changes that promote survival under the newest environmental conditions. When fungi enter the mammalian host their lifestyle changes from saprophytic to parasitic. As saprophytes, fungi survive in an environment with a moderate ambient temperature and pH ...
Virulence and Pathogenicity of Fungal Pathogens with
Virulence and Pathogenicity of Fungal Pathogens with

... by inducing transcriptional and translational changes that promote survival under the newest environmental conditions. When fungi enter the mammalian host their lifestyle changes from saprophytic to parasitic. As saprophytes, fungi survive in an environment with a moderate ambient temperature and pH ...
View Full Text-PDF
View Full Text-PDF

... resistivity pattern of Klebsiella isolates has been the global necessity. This study was done to determine the isolation rate of Klebsiella, their antibiogram and for the presence of resistant strains from various clinical samples. A total number of 698 pus, 312 sputum and 2176 urine samples were in ...
Download - 1,015Kb
Download - 1,015Kb

... are very low. The mutation induction methodology can be applied to improve many plant species. Two thousand, five hundred and forty three mutant cultivars of 175 plant species have been developed trough induction mutation; some of them are grown at large scales [3, 7]. Valuable progress has been rep ...
Plant Circadian Rhythms
Plant Circadian Rhythms

... heterodimer of the dCLOCK (dCLK) and CYCLE (CYC) transcription factors. The dCLK/CYC heterodimer also activates the transcription of vrille and Pdp1e, which encode negative and positive regulators, respectively, of clk transcription (Hardin, 2004). Thus, there are at least two interlocked feedback l ...
Adeno-Associated Virus Gene Therapy for Liver Disease
Adeno-Associated Virus Gene Therapy for Liver Disease

... functions in the body.9,10 These functions include carbohydrate use and storage, lipid metabolism, and hemostasis. In addition, the liver plays an important role in detoxifying naturally occurring metabolites such as ammonia and bilirubin. Numerous inherited metabolic disorders (IMDs) have their ori ...
Materials and methods
Materials and methods

... ETI is engaged following the recognition of microbial effectors via plant intracellular immune ...
The pericarp and its surface wax layer in maize kernels as
The pericarp and its surface wax layer in maize kernels as

... standards, at concentrations of 0, 222, 667, 2000 and 6000 mg g1 of fumonisins, were subjected to ELISA. Absorbance was measured at 450 nm with a microplate reader BioRad 680 (BioRad, USA). Concentration of total fumonisins in the samples was estimated on the basis of a logit–log function between f ...
Complement evasion strategies of pathogens
Complement evasion strategies of pathogens

... hence indirectly can block the pore formation. Bacteria do not only use vitronectin as a bridge for adhesion but also bind vitronectin in order to prevent the formation of the MAC and hereby significantly increase survival in serum. 3. Examples of binding of complement inhibitors to microbial pathoge ...
Full-text PDF - Explore Bristol Research
Full-text PDF - Explore Bristol Research

... of alternative dosing strategies when designing studies may help to push forward our understanding of how best to use Azithromycin and help to expand future treatment options. However, several key factors associated with drug adherence may be of particular relevance in the treatment of STIs and act ...
Genetic analysis of innate immunity in resistance to
Genetic analysis of innate immunity in resistance to

... used have been shown to influence overall lethality during infection.32 The three phenotypes most frequently measured to ascertain host response to C. albicans infection are tissue damage, fungal burden, and mortality, with each representing a different aspect of the host– fungus interaction.33 Tiss ...
PestFax Issue 15, July 2016 - Department of Agriculture and Food
PestFax Issue 15, July 2016 - Department of Agriculture and Food

... Doug Abrecht (DAFWA) reports that sclerotinia was also identified the week of 21-28 June in Nuseed GT50 canola seeded on 5 April 2016 at Merredin Research Station. There was also evidence of a low level of blackleg lesions on the leaves. At the time 30% of the canola plants were flowering, some had ...
expression of cd152 (ctla-4) in children with autoimmune thyroiditis
expression of cd152 (ctla-4) in children with autoimmune thyroiditis

... autoimmune diseases, especially thyroid autoimmune disease (1). The association between its polymorphisms and autoimmune disease was found in many populations, irrespectively of the ethnic origin (2). CTLA-4 gene is located on 2q33, close to genes of other regulatory molecules: CD28 and ICOS (3). It ...
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Plant disease resistance

Plant disease resistance protects plants from pathogens in two ways: by preformed mechanisms and by infection-induced responses of the immune system. Relative to a susceptible plant, disease resistance is the reduction of pathogen growth on or in the plant, while the term disease tolerance describes plants that exhibit little disease damage despite substantial pathogen levels. Disease outcome is determined by the three-way interaction of the pathogen, the plant and the environmental conditions (an interaction known as the disease triangle).Defense-activating compounds can move cell-to-cell and systemically through the plant vascular system. However, plants do not have circulating immune cells, so most cell types exhibit a broad suite of antimicrobial defenses. Although obvious qualitative differences in disease resistance can be observed when multiple specimens are compared (allowing classification as “resistant” or “susceptible” after infection by the same pathogen strain at similar inoculum levels in similar environments), a gradation of quantitative differences in disease resistance is more typically observed between plant strains or genotypes. Plants consistently resist certain pathogens but succumb to others; resistance is usually pathogen species- or pathogen strain-specific.
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