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Smoking Cessation Services
Smoking Cessation Services

... During January to March 2015 Pilot Open to all Optometrists and Dispensing Opticians Data collected by Public Health Wales due to be published at the end of 2015 Groundbreaking use of the profession – Wales Leads The Way! The Future – more use of high street services helping GPs, Pharmacists and oth ...
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Department of Ophthalmology, Kharkiv National Medical University
Department of Ophthalmology, Kharkiv National Medical University

... monitored in the dynamics of 32 patients (47 eyes) with preperimetric glaucoma of them men - 14, women - 18. The age of patients ranged from 40 to 77 years. Ophthalmic examination included conventional methods, automated static perimetry and optical coherence tomography. Observation periods were up ...
A Patient With Acute Visual Loss and Transient
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Who are the 100 most influential people in ophthalmology?
Who are the 100 most influential people in ophthalmology?

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First Presentation - Fundus Examination
First Presentation - Fundus Examination

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phototransduction
phototransduction

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sards
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Unilateral Retinitis Pigmentosa in One Eye and Tilted Hypoplastic
Unilateral Retinitis Pigmentosa in One Eye and Tilted Hypoplastic

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Visual System Powerpont file for students
Visual System Powerpont file for students

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Study questions - (canvas.brown.edu).
Study questions - (canvas.brown.edu).

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Retinal Gene Therapy Coming of Age
Retinal Gene Therapy Coming of Age

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Introduction to Genetics and Genomics
Introduction to Genetics and Genomics

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Word version of this scenario

... Sudden painless loss of vision A 74 year old South African male presents with sudden painless loss of vision in his right eye. This occurred shortly after waking. He has no associated symptoms and no past ocular history of note. His medical history includes hypertension, atrial fibrillation, and he ...
Eye Disease Fact Sheet RETINITIS PIGMENTOSA
Eye Disease Fact Sheet RETINITIS PIGMENTOSA

... vision loss. If these therapies are successful they might prevent a person who is treated when first diagnosed, from ever developing vision loss. Corrective therapies might also help slow the disease in people whose vision has already been affected, especially in the earlier stages. The corrective t ...
The University Eye Center proudly announces the establishment of
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... patients with known or suspected hereditary and developmental diseases of the retina and optic nerve. The clinic will be attended by Sherry J. Bass, OD, FAAO and Jerome Sherman, OD, FAAO, who are both Distinguished Teaching Professors and members of the clinical faculty at the SUNY State College of ...
High Resolution Adaptive Optics Scanning Laser Ophthalmoscopy
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... producing high resolution maps delineating the higher contrast capillary distribution of the same area of retina. AOSLO images were compared to SD-OCT (Heidelberg), fundus photography and fluorescein angiography. Results: AOSLO demonstrated abnormal blood flow within microaneurysms associated with B ...
Hereditary Retinal Dystrophies
Hereditary Retinal Dystrophies

... Inheritance - mainly autosomal-recessive; there is a rare autosomal-dominant variant. Presentation - childhood (aged about 6 years) to early adulthood: bilateral (usually) decreased central vision. This is often out of proportion to the clinical picture. There is also progressive colour blindness. P ...
Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE)
Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE)

... Patients with this syndrome can have colon cancer and skin tumors in addition to the retinal findings. If you are found to have these features, Dr. Schefler will refer you to a gastroenterologist and/or geneticist for further testing. If you have a family history of this disorder, it is important to ...
ReNeuron Group plc ReNeuron files application to commence
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... Pre-clinical studies carried out in disease models by the Company’s academic collaborators have demonstrated that, when transplanted into the retina, ReNeuron’s retinal progenitor cell technology has the potential to preserve existing photoreceptors, potentially reducing or halting further deteriora ...
Fundus photo showing bone spicules typical of Retinitis Fundus
Fundus photo showing bone spicules typical of Retinitis Fundus

... Mutations in over 50 genes have been shown to cause retinitis pigmentosa and there are three main categories of the disease; autosomal dominant, autosomal recessive and x-linked. The main difference between recessive genes and dominant genes is that in-order to develop the disease, you need two copi ...
BIOL 116T
BIOL 116T

... 3. dark current - constant stream of Na+ into photoreceptor cell a. light --> rhodopsin bleaching, blocks dark current b. light stimulation may be breaking down cGMP which causes Na+ channels to close ---> stops glutamic acid secretion by rod cell c. glutamic acid stimulates or inhibits bipolar cell ...
Starchville, J
Starchville, J

... XLRS phenotype.5 Of these, the most common variants include missense mutations affecting all regions of the protein.2 Any residual translation of the gene into the resulting protein likely results in an unstable, truncated polypeptide that would be rapidly degraded within the cell. Hence, the diseas ...
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Retinitis pigmentosa



Retinitis pigmentosa (RP) is an inherited, degenerative eye disease that causes severe vision impairment due to the progressive degeneration of the rod photoreceptor cells in the retina. This form of retinal dystrophy manifests initial symptoms independent of age; thus, RP diagnosis occurs anywhere from early infancy to late adulthood. Patients in the early stages of RP first notice compromised peripheral and dim light vision due to the decline of the rod photoreceptors. The progressive rod degeneration is later followed by abnormalities in the adjacent retinal pigment epithelium (RPE) and the deterioration of cone photoreceptor cells. As peripheral vision becomes increasingly compromised, patients experience progressive ""tunnel vision"" and eventual blindness. Affected individuals may additionally experience defective light-dark adaptations, nyctalopia (night blindness), and the accumulation of bone spicules in the fundus (eye).
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