Download High Resolution Adaptive Optics Scanning Laser Ophthalmoscopy

High Resolution Adaptive Optics Scanning Laser Ophthalmoscopy in Branch Retinal Vein
Occlusion
Hongxin Song1B, PhD, Mina Chung1A,1B, MD
A
Flaum Eye Institute, B Center for Visual Science, 1University of Rochester, Rochester, NY
Purpose: To assess changes in blood flow and the cone photoreceptor mosaic in branch retinal
vein occlusion (BRVO).
Methods: Adaptive optics scanning laser ophthalmoscopy (AOSLO) was used to evaluate the
macula of a patient with a history of branch retinal vein occlusion 7 years ago and subsequent
chronic cystoid macular edema. Reflectance imaging of the macular cone photoreceptors and
retinal vasculature was performed at 796nm wavelength and 5x7 degree montages were
generated. Standard deviation maps of the AOSLO images were generated from 50 frames,
producing high resolution maps delineating the higher contrast capillary distribution of the same
area of retina. AOSLO images were compared to SD-OCT (Heidelberg), fundus photography
and fluorescein angiography.
Results: AOSLO demonstrated abnormal blood flow within microaneurysms associated with
BRVO. Cone photoreceptors were present even within areas affected with cystoid macular
edema.
Conclusion: The retinal vasculature and abnormal blood flow in the setting of branch retinal
vein occlusion can be visualized using AOSLO. The ability to demonstrate the presence of
photoreceptors within cystoid macular edema may be a useful predictor of visual potential.
Financial Disclosure: N
Support: CTSI National Center for Research Resources, Research to Prevent Blindness