visualization, comparison and analysis of 2D maps of protein structure
... calculated 2D maps saved in the above-mentioned format, thus enabling comparison of e.g. computationally predicted and native maps. PROTMAP2D generates a particularly visually appealing output for MD trajectories comprising multiple conformations (e.g. from protein folding or unfolding simulations). ...
... calculated 2D maps saved in the above-mentioned format, thus enabling comparison of e.g. computationally predicted and native maps. PROTMAP2D generates a particularly visually appealing output for MD trajectories comprising multiple conformations (e.g. from protein folding or unfolding simulations). ...
Clean, Burn and Shape
... burning and cleansing. Do not pursue vigorous exercise on Clean Days and do not have more than two Clean Days in succession. ...
... burning and cleansing. Do not pursue vigorous exercise on Clean Days and do not have more than two Clean Days in succession. ...
SPA Enzyme Assay Design
... or generic. Another factor to consider when setting up the assay is that many enzymes require activation, either by post translational modification or the presence of co-factors, likely present in the cell lysate but for pure preparations it may be necessary to add any known co-factors. A wide range ...
... or generic. Another factor to consider when setting up the assay is that many enzymes require activation, either by post translational modification or the presence of co-factors, likely present in the cell lysate but for pure preparations it may be necessary to add any known co-factors. A wide range ...
lecture-4-radioimmunassay
... • The samples to be assayed (the unknowns) are run in parallel. • After determining the ratio of bound to free antigen in each unknown, the antigen concentrations can be read directly from the standard curve. ...
... • The samples to be assayed (the unknowns) are run in parallel. • After determining the ratio of bound to free antigen in each unknown, the antigen concentrations can be read directly from the standard curve. ...
Single Molecule Array (Simoa) technology for ultrasensitive
... Simoa HD-1 Analyzer • Unprecedented ultrasensitivity • Full automation • Precision • Wide dynamic range • Easy & cost-effective implementation • Multiplexing capability with small sample ...
... Simoa HD-1 Analyzer • Unprecedented ultrasensitivity • Full automation • Precision • Wide dynamic range • Easy & cost-effective implementation • Multiplexing capability with small sample ...
Designing Molecular Probes for the Detection of Gene Expression
... • Conventional Chemistries are inefficient (typically <10%) and are not site-specific ...
... • Conventional Chemistries are inefficient (typically <10%) and are not site-specific ...
magnetic nanoparticle simulation
... Diagram of microplate for separation of biomagnetic beads (96 wells with well pitch p = 9 mm) (top), cross section with dimensions in mm (bottom) ...
... Diagram of microplate for separation of biomagnetic beads (96 wells with well pitch p = 9 mm) (top), cross section with dimensions in mm (bottom) ...
Revealing kinase inhibitor mechanisms: ITC leads the way
... populate particular enzyme forms occurring along the reaction pathway, and so information on the relevant enzyme form for maximal affinity is sometimes difficult to obtain directly. ITC may overcome this limitation by measuring binding affinities to different, predetermined enzyme forms. Binding to ...
... populate particular enzyme forms occurring along the reaction pathway, and so information on the relevant enzyme form for maximal affinity is sometimes difficult to obtain directly. ITC may overcome this limitation by measuring binding affinities to different, predetermined enzyme forms. Binding to ...
Technical data sheet
... with the range from 352-441 amino acids. They also differ in either zero, one or two inserts of 29 amino acids at the N-terminal part (exon 2 and 3), and three or four repeat-binding regions at the C-terminus. So, the longest isoform in the CNS has four repeats (R1, R2, R3 and R4) and two inserts (4 ...
... with the range from 352-441 amino acids. They also differ in either zero, one or two inserts of 29 amino acids at the N-terminal part (exon 2 and 3), and three or four repeat-binding regions at the C-terminus. So, the longest isoform in the CNS has four repeats (R1, R2, R3 and R4) and two inserts (4 ...
can detect white spot syndrome virus (wssv
... immunohistochemistry using the monoclonal antibody. Haemolymph from individual shrimp was spotted onto a nitrocellulose membrane (1 µl/spot) and processed for dot blotting using the monoclonal antibody. Pooled haemolymph (10 µl from each individual) at each period of time after injection was tested ...
... immunohistochemistry using the monoclonal antibody. Haemolymph from individual shrimp was spotted onto a nitrocellulose membrane (1 µl/spot) and processed for dot blotting using the monoclonal antibody. Pooled haemolymph (10 µl from each individual) at each period of time after injection was tested ...
Lecture 25
... Antibodies to tumor antigens have advantages over other serum proteins as potential cancer biomarkers as they are stable, highly specific, easily purified from serum, and are readily detected with well-validated secondary reagents. The antibodies directed at self-antigens are referred to as autoanti ...
... Antibodies to tumor antigens have advantages over other serum proteins as potential cancer biomarkers as they are stable, highly specific, easily purified from serum, and are readily detected with well-validated secondary reagents. The antibodies directed at self-antigens are referred to as autoanti ...
Cytochrome P450 Proteins
... – Induction by quantifying the metabolite of a CYP-specific probe substrate generated from treated hepatocytes – Relies on the specificity of enzymatic conversion of probe substrates, and a different probe substrate is required for each CYP isozyme which is not always possible ...
... – Induction by quantifying the metabolite of a CYP-specific probe substrate generated from treated hepatocytes – Relies on the specificity of enzymatic conversion of probe substrates, and a different probe substrate is required for each CYP isozyme which is not always possible ...
Gel Electrophoresis
... • Electrophoresis is performed in buffer solutions (Electrophoresis buffers TBE) to reduce pH changes due to the electric field, which is important because the charge of DNA and RNA depends on pH • Running for too long can exhaust the buffering capacity of the solution so it should be changed from t ...
... • Electrophoresis is performed in buffer solutions (Electrophoresis buffers TBE) to reduce pH changes due to the electric field, which is important because the charge of DNA and RNA depends on pH • Running for too long can exhaust the buffering capacity of the solution so it should be changed from t ...
No Slide Title
... Types 4 and 1 are both active against mites, ticks, fleas • TYPE 4 activates macrophages which stimulate fibroblasts to produce granuloma and neutrophils to form intra-epidermal pustules IMMUNITY PARASITES ...
... Types 4 and 1 are both active against mites, ticks, fleas • TYPE 4 activates macrophages which stimulate fibroblasts to produce granuloma and neutrophils to form intra-epidermal pustules IMMUNITY PARASITES ...
Primary antibody deficiency
... ingest and kill than bacteria that are not coated with antibodies. ...
... ingest and kill than bacteria that are not coated with antibodies. ...
Supplementary methods
... following manufacturer instructions. Elastic fibres and collagen were stained with Orcein and Sirius Red solutions (Sigma), respectively. ...
... following manufacturer instructions. Elastic fibres and collagen were stained with Orcein and Sirius Red solutions (Sigma), respectively. ...
Indirect immunoprecipitations of labeled glycopro
... components may also be of importance, but complex formation does not seem to be greatly dependent on extraneous components, e.g. cytoskeletal elements. During the course of this study, itwas noted that different antisera with the same nominal specificityvaried in their efficiency to precipitate the ...
... components may also be of importance, but complex formation does not seem to be greatly dependent on extraneous components, e.g. cytoskeletal elements. During the course of this study, itwas noted that different antisera with the same nominal specificityvaried in their efficiency to precipitate the ...
Protocol Booklet
... Extraction Kit (ab117152) optimized for use with this product. The target protein bound DNA prepared with Abcam’s ChIP Kit Magnetic - One-Step can be used for various downstream applications including PCR (ChIPPCR), microarrays (ChIP-chip), and sequencing (ChIP-seq). ab156907 contains all necessary ...
... Extraction Kit (ab117152) optimized for use with this product. The target protein bound DNA prepared with Abcam’s ChIP Kit Magnetic - One-Step can be used for various downstream applications including PCR (ChIPPCR), microarrays (ChIP-chip), and sequencing (ChIP-seq). ab156907 contains all necessary ...
Cytochrome P450 3A4: The Impossible Protein
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
Prior Art - Cabic.com
... previously known to result in lowering blood pressure. The inventors assert they have newly produced a stable crystalline form of protein P. Protein P in crystalline form is inactive. The description gives experimental data with explanations of how to make the crystals. Common prior art meth ...
... previously known to result in lowering blood pressure. The inventors assert they have newly produced a stable crystalline form of protein P. Protein P in crystalline form is inactive. The description gives experimental data with explanations of how to make the crystals. Common prior art meth ...
Cytochrome P450 3A4: The Impossible Protein
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
Hardcastle, A., et. al. Pharmacodynamic markers of response to
... both catalogue and in-house assays used Provided proof of principle for mechanism of action in 2 therapeutic areas, HSP90 and HDAC, in different sample matrices Now used in a number of drug discovery projects in the Centre Assays are amenable to GCLP validation to comply with regulatory requ ...
... both catalogue and in-house assays used Provided proof of principle for mechanism of action in 2 therapeutic areas, HSP90 and HDAC, in different sample matrices Now used in a number of drug discovery projects in the Centre Assays are amenable to GCLP validation to comply with regulatory requ ...
D - Protein Information Resource
... We recently designed a PRotein Ontology (PRO) framework to facilitate protein annotation and to guide new experimental design (http://pir.georgetown.edu/pro/). PRO is an ontology of protein entities and relationships in the OBO Foundry framework. Its components extend from the evolutionary relations ...
... We recently designed a PRotein Ontology (PRO) framework to facilitate protein annotation and to guide new experimental design (http://pir.georgetown.edu/pro/). PRO is an ontology of protein entities and relationships in the OBO Foundry framework. Its components extend from the evolutionary relations ...