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3. Insulin titration and glucose monitoring AFTER initiation of infusion
3. Insulin titration and glucose monitoring AFTER initiation of infusion

... (example: if Insulin was running 2 units/hr and the glucose is falling, reduce the infusion by 0.5 units/hr to a final rate of 1.5 units/hr). c. Increased body temperature causes an increase in insulin requirements, particularly if caused by infection. Insulin needs decrease as the infection improve ...
Hypoglycaemia mgt of the adult inpatient with diabetes
Hypoglycaemia mgt of the adult inpatient with diabetes

... Hypoglycaemia results from an imbalance between glucose supply, glucose utilization, and insulin levels resulting in more insulin than is needed at that time (3) Hypoglycaemia is defined as a blood glucose level being equal or less than 4mmols/l, with or without symptoms (1). Hypoglycaemia can occur ...
DIABETIC KETOACIDOSIS (DKA)
DIABETIC KETOACIDOSIS (DKA)

... effective circulating insulin, insulin resistance and increased production of counter-regulatory hormones. The frequency of DKA ranges from 16%-80% of children newly diagnosed with diabetes, depending on geographic location. It is the leading cause of morbidity and is the most common cause of diabet ...
Polycystic Ovary Syndrome
Polycystic Ovary Syndrome

... Although the cause of PCOS is not known, it appears that PCOS may be related to many different factors working together. These factors include insulin resistance, increased levels of hormones called androgens, and an irregular menstrual cycle. ...


... The first step in the nutrition care process is nutrition assessment. Dietetics professionals use nutrition assessment in several ways  to determine a person‘s current nutrition status and needs  to develop a plan for improvement  to monitor the outcomes of interventions  to decide when to chang ...
Type 2 Diabetes Screening and Treatment Guideline
Type 2 Diabetes Screening and Treatment Guideline

... The risk of serious health conditions—such as high blood pressure, heart disease, arthritis, and stroke, as well as diabetes—increases with body mass index (BMI) of 25 or higher. (BMI = weight in kilograms divided by height in meters squared [kg/m2].) Overweight is defined as a BMI of 25 to 29.9, ob ...
Endocrine Drugs - My Illinois State
Endocrine Drugs - My Illinois State

... intake and help with weight control)  Available in liquid form (Riomet)  Also available in extended-release tablets (Fortamet, Glucophage XR)—Dose is taken once daily, best with the evening meal  Not metabolized; must be excreted by the kidney  High levels of metformin can cause fatal lactic aci ...
The Metabolic Syndrome and Glucose Intolerance
The Metabolic Syndrome and Glucose Intolerance

... imbalance between apoptosis and generation of new beta cells. Animal models of diabetes exhibit increased islet apoptosis, as seen in both diabetic and prediabetic Zucker diabetic fatty (ZDF) rats. Oxidative stress ap­pears to mediate the increase in apoptosis and fall in beta-cell mass because trea ...
Does identifying pre-diabetes
Does identifying pre-diabetes

... • Cardiovascular disease is the leading cause of death in the U.S. • One quarter of these deaths preventable • Modifiable risk factors include hypertension, obesity, cigarette use, inactivity, elevated cholesterol, and abnormal blood glucose • Type 2 diabetes develops slowly • Up to one decade betwe ...
View Newsletter - Bristlecone Behavioral Health
View Newsletter - Bristlecone Behavioral Health

... insulin facilitates and initiates the entire melodrama of fat storage. It’s not necessarily the level of insulin circulating in the blood which determines this melodious direction of fat (to storage or burning); but rather, is the responsiveness of the ‘orchestra of organs’ to the conductor’s cue. A ...
Chapter 6 Starvation and Diabetes Mellitus Starvation Glucose and
Chapter 6 Starvation and Diabetes Mellitus Starvation Glucose and

... of glucose in the urine) was added to differentiate it from diabetes insipidus (an unrelated disorder resulting from lack of anti-diuretic hormone action). Type I diabetes is also known as Insulin-Dependent Diabetes Mellitus (IDDM) and juvenile-onset diabetes. Most new cases are diagnosed during chi ...
Type 2 Diabetes Management Goals
Type 2 Diabetes Management Goals

... If HbA1c target not achieved after ~3 months of triple therapy and patient (1) on oral combination, move to injectables, (2) on GLP-1 RA, add basal insulin, or (3) on optimally titrated basal insulin, add GLP-1-RA or mealtime insulin. In refractory patients consider adding TZD or SGL T2-i: ...
Derek Sanders Diabetes Presentation
Derek Sanders Diabetes Presentation

... May be useful when new therapies such as enteral and parenteral nutrition or treatment with glucocorticoids is initiated “Routine and prolonged use is generally not recommended” “SSI regimens are not considered optimal physiologic insulin strategies because of a lack of evidence and efficacy.” Wides ...
Breastfeeding and Postpartum Implications for Infants and Women American Academy of Pediatrics
Breastfeeding and Postpartum Implications for Infants and Women American Academy of Pediatrics

... • Fat-some effect by diet related to type of fat and maternal body composition (increased SFA and UFA in diet increases concentration in breast milk) • Diet does not seem to alter the concentration of cholesterol and phospholipids in human milk • Diet consisting of <1,500 kcal/day have been shown to ...
Case Presentation
Case Presentation

... Marcia is a 40 year old woman who presents with polyuria, polydipsia and fatigue No ketonuria Her father has Type 2 diabetes BMI 32 Random BSL 28 mmol/L, Hba1c 12% How would you treat this patient? ...
deciding whether to transition your patient to mealtime insulin
deciding whether to transition your patient to mealtime insulin

... regular schedules and to more/less carb intake. • Studies have shown that adding just one mealtime dose of rapid acting insulin per day, given before the largest meal, improves glycemic control nearly as much as adding 2-3 doses per dayvii. • It’s an easier transition for many patients because the ...
S1 Protocol.
S1 Protocol.

... If successful, this proposal should help clarify the pathophysiologic mechanisms by which these key genetic variants increase risk of type 2 diabetes, and assess their impact on commonly used antidiabetic treatments. In addition, this pilot study will lay the groundwork for a long-term, outcomes-bas ...
Detection, Prevention, and Treatment of Hypoglycemia in the Hospital Fr om Resear
Detection, Prevention, and Treatment of Hypoglycemia in the Hospital Fr om Resear

... or Class IV heart disease, although the lingering effects of TZDs last several weeks.14 A common error in this population of patients is the discontinuation of oral agents in the absence of an alternate method for diabetes control. These patients should instead be converted to a subcutaneous or IV i ...
Diabetes mellitus and its relevance to the practice of dentistry
Diabetes mellitus and its relevance to the practice of dentistry

... employed treatment and involves subcutaneous administration of a long-acting basal insulin (e.g., Glargine/Detemir), which suppresses glucose production between meals and overnight, and a bolus injection of fast-acting insulin (e.g., Aspart/Lispro/Glulisine) at mealtimes to produce a peak coinciding ...
Lecture 6b Diabetes Management Chapter 19
Lecture 6b Diabetes Management Chapter 19

... • Insulin therapy for people with type 1 diabetes – Insulin preparations vary in how quickly they act, when their peak action occurs, and how long their effects last. – Intermediate- or long-acting insulin is used to meet basal needs. – Rapid- or short-acting insulin is used before each meal. – Clos ...
Slide 1
Slide 1

... An HbA1c or “A1c” test is the measure of the average blood glucose over the past 2-3 months. When BG are high, glucose molecules attach to the hemoglobin in RBCs. The longer hyperglycemia occurs, the more glucose binds to the RBC & the higher the A1c. ...
A1C - AACE Diabetes Resource Center
A1C - AACE Diabetes Resource Center

... Type 1 Diabetes Mellitus Treatment ...
What is continuous glucose monitoring?
What is continuous glucose monitoring?

... Daily self-monitoring of blood glucose provides people with diabetes the information they need to assess how food, physical activity and medications affect their blood glucose levels. Monitoring, however, doesn't stop there. People with diabetes also need to regularly check their blood pressure, uri ...
Antidiabetic Medications & The Nursing Process
Antidiabetic Medications & The Nursing Process

... Indications for Oral Hypoglycemics They are used to lower blood sugar levels in patients that diet and exercise have failed.  The patient must have some pancreatic function left.  They can be used as a monotherapy or in conjunction with other oral hypoglycemics. ...
Glucose Metabolism & Diabetes
Glucose Metabolism & Diabetes

... • Explain the processes of lipolysis, deamination glycogenolysis, and gluconeogenesis. • Define the terms glycosuria, polyuria, polydipsia, and polyphagia and explain why diabetes causes these ...
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Gestational diabetes



Gestational diabetes (or gestational diabetes mellitus, GDM) is a condition in which women without previously diagnosed diabetes exhibit high blood glucose (blood sugar) levels during pregnancy (especially during their third trimester). Gestational diabetes is caused when insulin receptors do not function properly. This is likely due to pregnancy-related factors such as the presence of human placental lactogen that interferes with susceptible insulin receptors. This in turn causes inappropriately elevated blood sugar levels.Gestational diabetes generally has few symptoms and it is most commonly diagnosed by screening during pregnancy. Diagnostic tests detect inappropriately high levels of glucose in blood samples. Gestational diabetes affects 3-10% of pregnancies, depending on the population studied.As with diabetes mellitus in pregnancy in general, babies born to mothers with untreated gestational diabetes are typically at increased risk of problems such as being large for gestational age (which may lead to delivery complications), low blood sugar, and jaundice. If untreated, it can also cause seizures or stillbirth. Gestational diabetes is a treatable condition and women who have adequate control of glucose levels can effectively decrease these risks. The food plan is often the first recommended target for strategic management of GDM.Women with unmanaged gestational diabetes are at increased risk of developing type 2 diabetes mellitus (or, very rarely, latent autoimmune diabetes or Type 1) after pregnancy, as well as having a higher incidence of pre-eclampsia and Caesarean section; their offspring are prone to developing childhood obesity, with type 2 diabetes later in life. Most women are able to manage their blood glucose levels with a modified diet and the introduction of moderate exercise, but some require antidiabetic drugs, including insulin.
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