IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... secretion, either of which may be the predominant feature. The important point here is that insulin secretion does not cease when the disease develops but may be inadequate for the purpose for which it is being secreted. There is usually too much carbohydrate to be metabolized for the amount of insu ...
... secretion, either of which may be the predominant feature. The important point here is that insulin secretion does not cease when the disease develops but may be inadequate for the purpose for which it is being secreted. There is usually too much carbohydrate to be metabolized for the amount of insu ...
Introduction 1.
... ά (TNF ά) in muscle cells has been implicated as an inducer of insulin resistance by increasing the serine phosphorylation of insulin receptor substrates (IRS-1) and (IRS-2), resulting in the reduction in the ability of the IRS molecules to dock with receptor and interact with downstream pathway (Le ...
... ά (TNF ά) in muscle cells has been implicated as an inducer of insulin resistance by increasing the serine phosphorylation of insulin receptor substrates (IRS-1) and (IRS-2), resulting in the reduction in the ability of the IRS molecules to dock with receptor and interact with downstream pathway (Le ...
Preeclampsia
... inexpensive, easy to perform, and should not expose the patient to discomfort or risk The technology should be widely available and the results reproducible and reliable, with a high likelihood ratio for a positive test (>15) and a low likelihood ratio for a negative result (<0.1) and good sensitivi ...
... inexpensive, easy to perform, and should not expose the patient to discomfort or risk The technology should be widely available and the results reproducible and reliable, with a high likelihood ratio for a positive test (>15) and a low likelihood ratio for a negative result (<0.1) and good sensitivi ...
Sodium-glucose cotransporter-2 inhibition for the reduction of
... in earlier studies. As per the prospective statistical analysis plan, hierarchical testing for all primary and secondary CV outcomes was performed combining the two empagliflozin doses for analysis. In the primary analysis, empagliflozin was proved statistically significantly noninferior to placebo ...
... in earlier studies. As per the prospective statistical analysis plan, hierarchical testing for all primary and secondary CV outcomes was performed combining the two empagliflozin doses for analysis. In the primary analysis, empagliflozin was proved statistically significantly noninferior to placebo ...
WORLD DIABETES DAY 10 NOV 2013 - Diabetic Society of Singapore
... it’s in your hands! By Rodiah Hashim ...
... it’s in your hands! By Rodiah Hashim ...
Diabetes CPG - Diabetes Malaysia
... can be greatly reduced by investing in promotive and preventive programmes particularly with regards to early detection of disease and prevention of complications. The system of care and monitoring provided in the previous CPG remains intact but adds new evidence for targets for control. The prevale ...
... can be greatly reduced by investing in promotive and preventive programmes particularly with regards to early detection of disease and prevention of complications. The system of care and monitoring provided in the previous CPG remains intact but adds new evidence for targets for control. The prevale ...
learning zone - Managing diabetic ketoacidosis
... should be increased to ten units per hour. When blood glucose is ≤15mmol/L, the infusion rate and fluids should be changed to a variable rate/sliding scale regimen (Box 2). In the unit where the author works, it has been found that basing the rate of insulin that is infused on the patient’s usual i ...
... should be increased to ten units per hour. When blood glucose is ≤15mmol/L, the infusion rate and fluids should be changed to a variable rate/sliding scale regimen (Box 2). In the unit where the author works, it has been found that basing the rate of insulin that is infused on the patient’s usual i ...
Diabetic Ketoacidosis
... • Serum bicarbonate < 10 mEq/l. • Anion gap > 12 mEq/l (normal gap 7-8 mEq/l) AG = (Na+) – (Cl- + HCO3) ...
... • Serum bicarbonate < 10 mEq/l. • Anion gap > 12 mEq/l (normal gap 7-8 mEq/l) AG = (Na+) – (Cl- + HCO3) ...
Type 2 diabetes and hypertension - COMDIS-HSD
... It will help to educate patients about lifestyle measures and specific treatments so individuals can take responsibility for their own care. This Case Management Desk Guide only includes brief lifestyle education messages and is accompanied by a Health Educator’s Desk Guide, for use by the health ed ...
... It will help to educate patients about lifestyle measures and specific treatments so individuals can take responsibility for their own care. This Case Management Desk Guide only includes brief lifestyle education messages and is accompanied by a Health Educator’s Desk Guide, for use by the health ed ...
PowerPoint プレゼンテーション - 埼玉医科大学総合医療センター 内分泌
... What these studies did show is: (1)the German study found that there is a decrease in both cancer risk and all-cause mortality when insulin glargine is compared to human insulin; (2)the Swedish study found no increase in overall cancer risk with insulin glargine, but for breast cancer an increased ...
... What these studies did show is: (1)the German study found that there is a decrease in both cancer risk and all-cause mortality when insulin glargine is compared to human insulin; (2)the Swedish study found no increase in overall cancer risk with insulin glargine, but for breast cancer an increased ...
Assessment 10 Endocrine
... o Women usually present with amenorrhea, hot flashes, night sweats, etc. due to lack of estradiol production Can have consequences such as osteoporosis, etc. o Progestin challenge test Has endometrium been subjected to any estradiol at all? Artificially give them progesterone to see if they re ...
... o Women usually present with amenorrhea, hot flashes, night sweats, etc. due to lack of estradiol production Can have consequences such as osteoporosis, etc. o Progestin challenge test Has endometrium been subjected to any estradiol at all? Artificially give them progesterone to see if they re ...
Glucose Control in ICU (8/24/16)
... Patients tend to be quite sensitive to insulin. Can start insulin at 0.05 U/kg rather than 0.1 U/kg. In severe hypotension, do not start insulin. This will exacerbation hypotension and will not have effective delivery of insulin until circulating volume is improved. Fall of glucose not tracked as cl ...
... Patients tend to be quite sensitive to insulin. Can start insulin at 0.05 U/kg rather than 0.1 U/kg. In severe hypotension, do not start insulin. This will exacerbation hypotension and will not have effective delivery of insulin until circulating volume is improved. Fall of glucose not tracked as cl ...
What’s going on?? - Rutgers University
... Most African Americans with diabetes have Type 2, which develops in adulthood and requires treatment with some combination of exercise, proper diet, medication and injected insulin African Americans are 1.8 times more likely to have diabetes than other ethnicities. Obesity has reached near epidemic ...
... Most African Americans with diabetes have Type 2, which develops in adulthood and requires treatment with some combination of exercise, proper diet, medication and injected insulin African Americans are 1.8 times more likely to have diabetes than other ethnicities. Obesity has reached near epidemic ...
Helping Your Patients Become Active
... decreasing. With vigorous exercise, such as resistance training or intense aerobic training, metabolic demand increases. This leads to an increase in hepatic glucose production and results in hyperglycemia. In people with type 1 diabetes, the pancreas is unable to regulate insulin based on blood glu ...
... decreasing. With vigorous exercise, such as resistance training or intense aerobic training, metabolic demand increases. This leads to an increase in hepatic glucose production and results in hyperglycemia. In people with type 1 diabetes, the pancreas is unable to regulate insulin based on blood glu ...
care of the clients
... Common Diagnostic Procedures for the Endocrine System Evaluation Various tests have been employed to confirm or rule put endocrinal diseases. Tests are done to identify hyperfunction and hypofunction. Test can be direct, indirect and provocative. HORMONE ASSAY This is a direct test that measures h ...
... Common Diagnostic Procedures for the Endocrine System Evaluation Various tests have been employed to confirm or rule put endocrinal diseases. Tests are done to identify hyperfunction and hypofunction. Test can be direct, indirect and provocative. HORMONE ASSAY This is a direct test that measures h ...
Management of Inpatient Hyperglycemia in Special Populations
... General Guidelines for Glucose Control and Glucocorticoid Therapy • The majority of patients (but not all) receiving highdose glucocorticoid therapy will experience elevations in blood glucose, which are often marked • Suggested approach – Institute glucose monitoring for at least 48 h in all patie ...
... General Guidelines for Glucose Control and Glucocorticoid Therapy • The majority of patients (but not all) receiving highdose glucocorticoid therapy will experience elevations in blood glucose, which are often marked • Suggested approach – Institute glucose monitoring for at least 48 h in all patie ...
DKA guidelines
... The instructions given above are based on consensus recommendations considering general populations of patients Individual inpatient requirements for insulin may vary significantly: o For patients taking insulin at home, the adequacy of glucose control at baseline will have an impact on transiti ...
... The instructions given above are based on consensus recommendations considering general populations of patients Individual inpatient requirements for insulin may vary significantly: o For patients taking insulin at home, the adequacy of glucose control at baseline will have an impact on transiti ...
Diabetes Management Guidelines
... and the urgent need for insulin replacement therapy because of the risk of ketoacidosis and death.Patientsareusuallylessthan30yearsbutitcanpresentinolderpatients.Theonsetof symptomsismorerapidandketonesareusuallypresent. Atpresentation,thepatientwithsus ...
... and the urgent need for insulin replacement therapy because of the risk of ketoacidosis and death.Patientsareusuallylessthan30yearsbutitcanpresentinolderpatients.Theonsetof symptomsismorerapidandketonesareusuallypresent. Atpresentation,thepatientwithsus ...
UNIT 17 Disorders of Glucose Metabolism
... Note: There is a change to the diagnostic criteria for diabetes given in McCance and Huether. The fasting plasma glucose diagnostic level for the standard oral glucose tolerance test OGTT has been lowered from 7.8 mmol/L (140 mg/dl) to 7 mmol/L (126 mg/dl) and therefore criteria 2 on page 673 should ...
... Note: There is a change to the diagnostic criteria for diabetes given in McCance and Huether. The fasting plasma glucose diagnostic level for the standard oral glucose tolerance test OGTT has been lowered from 7.8 mmol/L (140 mg/dl) to 7 mmol/L (126 mg/dl) and therefore criteria 2 on page 673 should ...
Pre-test for Glucose Metabolism
... hyperglycemia due to defective insulin secretion, insulin action or both. Diabetes mellitus is a serious health problem affecting 5% of Canadians. American data indicates that diagnosis of diabetes may be underestimated by almost half, which may mean that up to 10% of Canadians are diabetic. In the ...
... hyperglycemia due to defective insulin secretion, insulin action or both. Diabetes mellitus is a serious health problem affecting 5% of Canadians. American data indicates that diagnosis of diabetes may be underestimated by almost half, which may mean that up to 10% of Canadians are diabetic. In the ...
Type 2 diabetes: is it serious?
... complications that result in significant morbidity and mortality. Diettreated type 2 diabetes is often regarded as a ‘mild’ form of the disease. Complications occur largely as a result of inadequate blood glucose control. Type 2 diabetes and its complications can be present without any of the classi ...
... complications that result in significant morbidity and mortality. Diettreated type 2 diabetes is often regarded as a ‘mild’ form of the disease. Complications occur largely as a result of inadequate blood glucose control. Type 2 diabetes and its complications can be present without any of the classi ...
Plasma sex steroid hormones and risk of developing type 2 diabetes
... supplementary questionnaires to confirm diabetes symptoms and provide results from fasting glucose and oral glucose tolerance tests, as well as details of treatments. Diabetes was confirmed according to the American Diabetes Association criteria of 1997. Previous Women’s Health Study diabetes valida ...
... supplementary questionnaires to confirm diabetes symptoms and provide results from fasting glucose and oral glucose tolerance tests, as well as details of treatments. Diabetes was confirmed according to the American Diabetes Association criteria of 1997. Previous Women’s Health Study diabetes valida ...
Glycaemic Control in Type 2 Diabetes
... Combination therapy (with Metformin, sulphonylurea) Where insulin is unacceptable to the patient Consider referral to the Diabetes Specialist Team Mechanism of action Glucagon Like Peptide (GLP)-1 is one of the key ‘incretin’ hormones - a group of rapidly metabolised peptides secreted from the gut i ...
... Combination therapy (with Metformin, sulphonylurea) Where insulin is unacceptable to the patient Consider referral to the Diabetes Specialist Team Mechanism of action Glucagon Like Peptide (GLP)-1 is one of the key ‘incretin’ hormones - a group of rapidly metabolised peptides secreted from the gut i ...
Infant Body Composition and Adipokine Concentrations in Relation
... span, thus raising the trajectory for diabetes even before the baby is born. Although the mechanisms through which these processes occur are poorly understood, overweight and obesity in offspring of diabetic pregnancies are well documented (19,20), highlighting a potential mediating role of adipocyt ...
... span, thus raising the trajectory for diabetes even before the baby is born. Although the mechanisms through which these processes occur are poorly understood, overweight and obesity in offspring of diabetic pregnancies are well documented (19,20), highlighting a potential mediating role of adipocyt ...
Gestational diabetes
Gestational diabetes (or gestational diabetes mellitus, GDM) is a condition in which women without previously diagnosed diabetes exhibit high blood glucose (blood sugar) levels during pregnancy (especially during their third trimester). Gestational diabetes is caused when insulin receptors do not function properly. This is likely due to pregnancy-related factors such as the presence of human placental lactogen that interferes with susceptible insulin receptors. This in turn causes inappropriately elevated blood sugar levels.Gestational diabetes generally has few symptoms and it is most commonly diagnosed by screening during pregnancy. Diagnostic tests detect inappropriately high levels of glucose in blood samples. Gestational diabetes affects 3-10% of pregnancies, depending on the population studied.As with diabetes mellitus in pregnancy in general, babies born to mothers with untreated gestational diabetes are typically at increased risk of problems such as being large for gestational age (which may lead to delivery complications), low blood sugar, and jaundice. If untreated, it can also cause seizures or stillbirth. Gestational diabetes is a treatable condition and women who have adequate control of glucose levels can effectively decrease these risks. The food plan is often the first recommended target for strategic management of GDM.Women with unmanaged gestational diabetes are at increased risk of developing type 2 diabetes mellitus (or, very rarely, latent autoimmune diabetes or Type 1) after pregnancy, as well as having a higher incidence of pre-eclampsia and Caesarean section; their offspring are prone to developing childhood obesity, with type 2 diabetes later in life. Most women are able to manage their blood glucose levels with a modified diet and the introduction of moderate exercise, but some require antidiabetic drugs, including insulin.