PPTX
... • Do we know all participants of the complex? • Do we have (open) sets of participants? • How do we indicate the depth of data available, i.e. compare Reactome import vs. manual curation? ...
... • Do we know all participants of the complex? • Do we have (open) sets of participants? • How do we indicate the depth of data available, i.e. compare Reactome import vs. manual curation? ...
Protein Degradation, Volume 1 ch01_p 1..9
... examined. According to the concept of Folin, most exogenously administered leucine should have appeared in urinary waste products. This was not the case: less than one-third of the isotope was excreted in the urine, and most of it was found to be incorporated into tissue proteins [2]. Since the weig ...
... examined. According to the concept of Folin, most exogenously administered leucine should have appeared in urinary waste products. This was not the case: less than one-third of the isotope was excreted in the urine, and most of it was found to be incorporated into tissue proteins [2]. Since the weig ...
Coarse-grained normal mode analysis in structural biology
... define the nodes is shown. Once the EN model is constructed, various motions are calculable by NMA, ranging from the level of the entire molecule to domains and individual residues. (e) The global motions computed for the GroEL–GroES complex (PDB code 1gru) [68], revealing a counter-rotation of the ...
... define the nodes is shown. Once the EN model is constructed, various motions are calculable by NMA, ranging from the level of the entire molecule to domains and individual residues. (e) The global motions computed for the GroEL–GroES complex (PDB code 1gru) [68], revealing a counter-rotation of the ...
Insulin-like Growth Factor-I (IGF-I) (Human) Cat. No. HEGFP
... The ED50 determined by a cell proliferation assay using serum free human MCF-7 cells is less than 2 ng/mL, corresponding to a specific activity of > 5.0 × 105 IU/mg. ...
... The ED50 determined by a cell proliferation assay using serum free human MCF-7 cells is less than 2 ng/mL, corresponding to a specific activity of > 5.0 × 105 IU/mg. ...
H - Free
... immobilisation of DNA. 3.2 Physical adsorption to the surface Many materials (e.g. glass, gold, silica gel) adsorb proteins on their surfaces. No reagents are required in this method. Proteins usually loose their 3D structure and biological recognition ability. 3.3 Biological interactions: affinity ...
... immobilisation of DNA. 3.2 Physical adsorption to the surface Many materials (e.g. glass, gold, silica gel) adsorb proteins on their surfaces. No reagents are required in this method. Proteins usually loose their 3D structure and biological recognition ability. 3.3 Biological interactions: affinity ...
Module 17 / Microscopic Level—The Sarcomere
... filaments) are organized into parallel units. Sarcomeres were first identified by imaging (histology), and the nomenclature described below reflects their microscopic "appearance." ...
... filaments) are organized into parallel units. Sarcomeres were first identified by imaging (histology), and the nomenclature described below reflects their microscopic "appearance." ...
Publication JournalArticle (Originalarbeit in einer wissenschaftlichen
... Keywords ANTP, HOX, bip2, dTAF3, Drosophila, eye-to-wing transformation, homeotic transformation HOX genes specify segment identity along the anteroposterior axis of the embryo. They code for transcription factors harbouring the highly conserved homeodomain and a YPWM motif, situated amino terminall ...
... Keywords ANTP, HOX, bip2, dTAF3, Drosophila, eye-to-wing transformation, homeotic transformation HOX genes specify segment identity along the anteroposterior axis of the embryo. They code for transcription factors harbouring the highly conserved homeodomain and a YPWM motif, situated amino terminall ...
the proposal
... interactions can coexist with physical interactions. For example, hemoglobin senses the binding of oxygen and transmits the information from one of its subunits to the others via physical interaction. ...
... interactions can coexist with physical interactions. For example, hemoglobin senses the binding of oxygen and transmits the information from one of its subunits to the others via physical interaction. ...
The SPFH domain - Tavernarakis Lab
... domain, after the initials of the related protein families: stomatins, prohibitins, flotillins and HflK/C. The core motif of this domain is partially described in the Pfam database (Pfam entry: Band_7, accession ...
... domain, after the initials of the related protein families: stomatins, prohibitins, flotillins and HflK/C. The core motif of this domain is partially described in the Pfam database (Pfam entry: Band_7, accession ...
Microscopic Level—The Sarcomere
... Thin filaments, composed of actin, attach to a protein in the Z disc (or Z line) called alpha-actinin, and they are present across the entire length of the I band and a portion of the A band. The region where thick and thin filaments overlap has a dense appearance, as there is little space between ...
... Thin filaments, composed of actin, attach to a protein in the Z disc (or Z line) called alpha-actinin, and they are present across the entire length of the I band and a portion of the A band. The region where thick and thin filaments overlap has a dense appearance, as there is little space between ...
Expression of Hepatitis C Virus Structural Proteins in
... efficient replication of HCV, it is hard to prove that the aggregates can be formed in the course of infection. However, this tendency to form aggregates is not an artifact linked to the expression system, but probably an intrinsic property of these proteins [6-8]. The inefficient folding of HCV str ...
... efficient replication of HCV, it is hard to prove that the aggregates can be formed in the course of infection. However, this tendency to form aggregates is not an artifact linked to the expression system, but probably an intrinsic property of these proteins [6-8]. The inefficient folding of HCV str ...
The Amino Acid Sequence of Chlorella fusca Plastocyanin
... 1958) and Azotobacter (cytochrome cs; Tissieres, 1956) contain proteins with a-band maxima at about 555nm. In studies of other cytochromes from pseudomonads, we have frequently met with cytochromes of the cs type, but chroniatographic properties and yields have been very erratic. All purifications u ...
... 1958) and Azotobacter (cytochrome cs; Tissieres, 1956) contain proteins with a-band maxima at about 555nm. In studies of other cytochromes from pseudomonads, we have frequently met with cytochromes of the cs type, but chroniatographic properties and yields have been very erratic. All purifications u ...
Chemistry Worksheet Name: ___________________________ Functional Groups and Amino Acids
... Name: ___________________________ Block: ___________ ...
... Name: ___________________________ Block: ___________ ...
Study Guide for Midterm 3 – Chem 109 C
... to steric repulsion - adjacent amino acids can't have the same charge ( for example two lys) due to electrostatic repulsion B. Beta pleated sheet - extended zigzag structure - parallel beta sheets have the adjacent chains both running N end to C end - anti parallel beta sheets run in opposite direct ...
... to steric repulsion - adjacent amino acids can't have the same charge ( for example two lys) due to electrostatic repulsion B. Beta pleated sheet - extended zigzag structure - parallel beta sheets have the adjacent chains both running N end to C end - anti parallel beta sheets run in opposite direct ...
Computational Biology
... Proteins that make up multimeric structural complexes are likely to have similar profiles. Also, proteins that are known to participate in a given biochemical pathway are likely to be neighbors in the space of phylogenetic profiles. Proteins that are functionally linked are far more likely to be nei ...
... Proteins that make up multimeric structural complexes are likely to have similar profiles. Also, proteins that are known to participate in a given biochemical pathway are likely to be neighbors in the space of phylogenetic profiles. Proteins that are functionally linked are far more likely to be nei ...
Biological Polymers - McQuarrie General Chemistry
... water. This interplay causes the protein to coil, fold, and bend into a three-dimensional shape called the tertiary structure. The tertiary structure of a protein can be obtained from X-ray analysis. Because proteins play crucial roles in nearly all biological processes, an active area of biochemica ...
... water. This interplay causes the protein to coil, fold, and bend into a three-dimensional shape called the tertiary structure. The tertiary structure of a protein can be obtained from X-ray analysis. Because proteins play crucial roles in nearly all biological processes, an active area of biochemica ...
Quantitative profiling of differentiation
... paired with another signal. The automated precursor ion selection afforded by the mass spectrometer, together with the exclusion of peptides previously sequenced within a user-defined time window (dynamic exclusion), permitted the analysis by collision-induced dissociation (CID) of 12 of the peptide ...
... paired with another signal. The automated precursor ion selection afforded by the mass spectrometer, together with the exclusion of peptides previously sequenced within a user-defined time window (dynamic exclusion), permitted the analysis by collision-induced dissociation (CID) of 12 of the peptide ...
acbp-1
... fatty acids, are important intermediates in both anabolic and catabolic processes, but have also been identified as regulators of ion channels, enzymes, membrane fusion, and gene expression. Acyl-CoA binding protein (ACBP) is a small, primarily cytosolic protein, which binds acyl-CoA esters with hig ...
... fatty acids, are important intermediates in both anabolic and catabolic processes, but have also been identified as regulators of ion channels, enzymes, membrane fusion, and gene expression. Acyl-CoA binding protein (ACBP) is a small, primarily cytosolic protein, which binds acyl-CoA esters with hig ...
Post-translational Modifications and Their
... proteins in signaling pathways will make it possible to find the common basis of biological regulation. Phosphorylation and dephosphorylation on S, T, Y and H residues are the best known modifications involved in reversible, activation and inactivation of enzyme activity and modulation of molecular ...
... proteins in signaling pathways will make it possible to find the common basis of biological regulation. Phosphorylation and dephosphorylation on S, T, Y and H residues are the best known modifications involved in reversible, activation and inactivation of enzyme activity and modulation of molecular ...
an eGOcentric view of tOrC1 signaling
... The structurally and functionally conserved target of rapamycin complex 1 (TORC1) plays a pivotal role in the control of eukaryotic cell growth by promoting anabolic processes (such as protein synthesis) and inhibiting catabolic processes (such as autophagy) in response to diverse signals including ...
... The structurally and functionally conserved target of rapamycin complex 1 (TORC1) plays a pivotal role in the control of eukaryotic cell growth by promoting anabolic processes (such as protein synthesis) and inhibiting catabolic processes (such as autophagy) in response to diverse signals including ...
Hydrophobic Interaction Chromatography (HIC
... *Hydrophobic literally means “water fearing.” It refers to substances that do not mix well with water (i.e., Oil is hydrophobic). Note how it stays together in small beads and does not mix with water. Purpose: To separate hydrophobic proteins based on their tendency to stick to specially treated bea ...
... *Hydrophobic literally means “water fearing.” It refers to substances that do not mix well with water (i.e., Oil is hydrophobic). Note how it stays together in small beads and does not mix with water. Purpose: To separate hydrophobic proteins based on their tendency to stick to specially treated bea ...
Jake Wang - Critical Review of the Rosetta Algorithm
... Jake Wang Biochemistry 218 Final Project I. Introduction Proteins are linear chains of amino acids that evolved the property of folding into unique three-dimensional structures in order to perform complex biological functions. Determining their structures has far-reaching implications in science and ...
... Jake Wang Biochemistry 218 Final Project I. Introduction Proteins are linear chains of amino acids that evolved the property of folding into unique three-dimensional structures in order to perform complex biological functions. Determining their structures has far-reaching implications in science and ...
6 II. PRIMARY STRUCTURE OF PROTEINS A. Peptide bond
... • The linear sequence of the linked amino acids contains the information necessary to generate a protein molecule with a unique three-dimensional shape. • The complexity of protein structure is best analyzed by considering the molecule in terms of four organizational levels: • primary, secondary, te ...
... • The linear sequence of the linked amino acids contains the information necessary to generate a protein molecule with a unique three-dimensional shape. • The complexity of protein structure is best analyzed by considering the molecule in terms of four organizational levels: • primary, secondary, te ...
Screening for novel snake venom toxins using protein chemistry and molecular biology.
... We have been involved in isolation and characterization of novel toxins from snake venoms and identified a number of new toxins that belong to known family of toxins, but with different biological properties. We have also identified a few new families of snake venom toxins. The new toxins include (a ...
... We have been involved in isolation and characterization of novel toxins from snake venoms and identified a number of new toxins that belong to known family of toxins, but with different biological properties. We have also identified a few new families of snake venom toxins. The new toxins include (a ...
Intrinsically disordered proteins
An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules.