Technical data sheet
... in neurons of the central nervous system, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes and elsewhere. One of tau's main functions is to modulate the stability of axonal microtubules. Tau is active primarily in the distal portions of axons providing microtubule sta ...
... in neurons of the central nervous system, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes and elsewhere. One of tau's main functions is to modulate the stability of axonal microtubules. Tau is active primarily in the distal portions of axons providing microtubule sta ...
Phosphoproteomics reveals extensive in vivo phosphorylation of
... the non-redundant Arabidopsis thaliana protein database from NCBI using the Bioworks Browser 3.1 SR1 (Thermo Electron). The following modifications were entered in the search. Static: methylation of Asp/Glu and peptide C-termini (+14 Da); carbamidomethylation of Cys (+57 Da). Variable: oxidation of ...
... the non-redundant Arabidopsis thaliana protein database from NCBI using the Bioworks Browser 3.1 SR1 (Thermo Electron). The following modifications were entered in the search. Static: methylation of Asp/Glu and peptide C-termini (+14 Da); carbamidomethylation of Cys (+57 Da). Variable: oxidation of ...
Single-stranded DNA-binding Proteins
... polypeptide can be used to interact in a nonsequencespecific manner to the ssDNA. These generalized electrostatic or hydrogen-bonding interactions between amino acid side-chains from the protein to the phosphodiester backbone and bases of the DNA are ubiquitous but make up only a part of the energy a ...
... polypeptide can be used to interact in a nonsequencespecific manner to the ssDNA. These generalized electrostatic or hydrogen-bonding interactions between amino acid side-chains from the protein to the phosphodiester backbone and bases of the DNA are ubiquitous but make up only a part of the energy a ...
Explain advantages of Carbohydrates Lipids Proteins
... Carbohydrates can be divided into two groups: complex and simple. Simple carbohydrates include lactose, sucrose, fructose, and other sugars. Complex carbohydrates include starches and fiber. You can find complex carbohydrates in beans, peas, whole grains, oatmeal, and rice. A longer time period is n ...
... Carbohydrates can be divided into two groups: complex and simple. Simple carbohydrates include lactose, sucrose, fructose, and other sugars. Complex carbohydrates include starches and fiber. You can find complex carbohydrates in beans, peas, whole grains, oatmeal, and rice. A longer time period is n ...
6 systems biology of cell organization
... translation and typically exist for just several minutes or a few hours (Figure 6.1f ). As discussed later, cells have different mechanisms to degrade proteins to individual amino acids so that the amino acids can be recycled— that is, used to make new proteins. ...
... translation and typically exist for just several minutes or a few hours (Figure 6.1f ). As discussed later, cells have different mechanisms to degrade proteins to individual amino acids so that the amino acids can be recycled— that is, used to make new proteins. ...
Reading Guide: Pratt and Cornely, Chapter 5.1 1. Compare and
... Reading Guide: Pratt and Cornely, Chapter 5.1 1. Compare and contrast the roles of myoglobin and hemoglobin. 2. Describe the major structural features of myoglobin and how they are similar/different than hemoglobin. 3. Draw a simple schematic of the ligands that bind to the iron ion found in myoglob ...
... Reading Guide: Pratt and Cornely, Chapter 5.1 1. Compare and contrast the roles of myoglobin and hemoglobin. 2. Describe the major structural features of myoglobin and how they are similar/different than hemoglobin. 3. Draw a simple schematic of the ligands that bind to the iron ion found in myoglob ...
CHAPTER 1 PATHOGENESIS OF GOUSIEKTE 1.1
... Titin in the I-band exhibits elastic behaviour upon sarcomeric stretch, contributing to the passive tension of cardiac muscle (Fig. 2.1). The extensible I-band region of titin has multiple segments: the tandemly arranged Ig (immunoglobulin-like) segments, N2B, N2A and the PEVK region, so called beca ...
... Titin in the I-band exhibits elastic behaviour upon sarcomeric stretch, contributing to the passive tension of cardiac muscle (Fig. 2.1). The extensible I-band region of titin has multiple segments: the tandemly arranged Ig (immunoglobulin-like) segments, N2B, N2A and the PEVK region, so called beca ...
Macromolecules Exercise Ver8 - STAR
... membranes. In an organism, lipids are a source of stored energy, serve to insulate the body and are found inside ALL different cell types. Below are EXAMPLES of 1) one of the building blocks of lipids, 2) a lipid, and 3) a biological environment abundant in lipids. Ver. 9 ...
... membranes. In an organism, lipids are a source of stored energy, serve to insulate the body and are found inside ALL different cell types. Below are EXAMPLES of 1) one of the building blocks of lipids, 2) a lipid, and 3) a biological environment abundant in lipids. Ver. 9 ...
Centrosomes as Scaffolds - Albert Einstein College of Medicine
... 1999). With the advent of techniques such as immunogold electron microscopy and improved immunofluorescence techniques, it is now possible to identify structural proteins of Boveri’s “centroplasm.” These techniques have unveiled new possibilities for the centrosome as an organizer of cell cycle asso ...
... 1999). With the advent of techniques such as immunogold electron microscopy and improved immunofluorescence techniques, it is now possible to identify structural proteins of Boveri’s “centroplasm.” These techniques have unveiled new possibilities for the centrosome as an organizer of cell cycle asso ...
29. protein targeting and degradation
... Proteins which are to be exported out of the cell are synthesized by ribosomes, associated with the ER. The genetic information from DNA is transferred via RNA. This information determines how the amino acids build up the proteins. First, a signal peptide is formed as a part of the protein. With the ...
... Proteins which are to be exported out of the cell are synthesized by ribosomes, associated with the ER. The genetic information from DNA is transferred via RNA. This information determines how the amino acids build up the proteins. First, a signal peptide is formed as a part of the protein. With the ...
Protein-Chemistry_Svar-lektionsuppgifter
... b) Enzyme catalyzed reactions are monomolecular, while this uncatalyzed reaction is bimolecular. The reacting groups are close to one another with correct orientation in the active site, which is entropically favorable. c) kcat/KM = 4.6x103/1,2x10-4 = 3.8x107 M-1s-1< kdiff = 108-109 M-1s-1 The rate ...
... b) Enzyme catalyzed reactions are monomolecular, while this uncatalyzed reaction is bimolecular. The reacting groups are close to one another with correct orientation in the active site, which is entropically favorable. c) kcat/KM = 4.6x103/1,2x10-4 = 3.8x107 M-1s-1< kdiff = 108-109 M-1s-1 The rate ...
Production and Purification of Recombinant Fluorescent Protein
... demonstrated to be no less viable than corresponding wild type cells . In live cells, fluorescent proteins are most commonly employed to track the localization and dynamics of proteins, organelles, and other cellular compartments. A variety of techniques have been developed to construct fluorescent ...
... demonstrated to be no less viable than corresponding wild type cells . In live cells, fluorescent proteins are most commonly employed to track the localization and dynamics of proteins, organelles, and other cellular compartments. A variety of techniques have been developed to construct fluorescent ...
Leukaemia Section t(9;22)(q34;q11) in ANLL Atlas of Genetics and Cytogenetics
... The crucial event lies on der(22), id est 5' BCR/3' ABL hybrid gene is pathogenic, while ABL/BCR may or may not be expressed; Breakpoint in ABL is variable over a region of 200 kb, often between the two alternative exons 1b and 1a, sometimes 5' of 1b, or 3' of 1a, but always 5' of exon 2; Breakpoint ...
... The crucial event lies on der(22), id est 5' BCR/3' ABL hybrid gene is pathogenic, while ABL/BCR may or may not be expressed; Breakpoint in ABL is variable over a region of 200 kb, often between the two alternative exons 1b and 1a, sometimes 5' of 1b, or 3' of 1a, but always 5' of exon 2; Breakpoint ...
Adaptive Silver Films for Detection of Antibody Binding
... features unique to different conformational states, which is in agreement with X-ray crystallographic studies.20 In this paper we demonstrate that SERS substrates based on nanostructured adaptive silver films (ASFs) make it possible to detect the formation of specific antigen-antibody complexes at a ...
... features unique to different conformational states, which is in agreement with X-ray crystallographic studies.20 In this paper we demonstrate that SERS substrates based on nanostructured adaptive silver films (ASFs) make it possible to detect the formation of specific antigen-antibody complexes at a ...
#315: Ribosomes: Unlocking the secrets to your cellular protein
... So I thought stress is what I should exploit in order to get crystals. So actually I worked only on three different bacteria, all of them crystallised. Knowledge about how these bacteria live was a good start. I thought that if bacteria lives at 80 degrees centigrade or in the Dead Sea where there i ...
... So I thought stress is what I should exploit in order to get crystals. So actually I worked only on three different bacteria, all of them crystallised. Knowledge about how these bacteria live was a good start. I thought that if bacteria lives at 80 degrees centigrade or in the Dead Sea where there i ...
Protein folding
... that transiently associate with newly synthesized proteins and promote their folding. • Misfolded proteins are retained and subsequently degraded by the ER-associated degradation. • Protein misfolding is the cause of several genetic diseases. • Chemical chaperones are small molecules that bind to a ...
... that transiently associate with newly synthesized proteins and promote their folding. • Misfolded proteins are retained and subsequently degraded by the ER-associated degradation. • Protein misfolding is the cause of several genetic diseases. • Chemical chaperones are small molecules that bind to a ...
instructions on the annotation of pdf files
... boundaries that may differ in the two databases. We also required that each domain is formed by a continuous sequence of 50–300 residues and is, thus, in the range where ACO and chain length were shown to have predictive value. Finally, we only considered two-domain proteins in which the combined le ...
... boundaries that may differ in the two databases. We also required that each domain is formed by a continuous sequence of 50–300 residues and is, thus, in the range where ACO and chain length were shown to have predictive value. Finally, we only considered two-domain proteins in which the combined le ...
Table S17. P. gigantea hydrophobin models Existing model
... structure appeared to be more similar with the homologue from P. chrysosporum. In C. subvermispora however, the first exon was relatively large in comparison with the other two homologues. This structural variation did not affect the size of the gene in the abovementioned species. Model 80088 lacks ...
... structure appeared to be more similar with the homologue from P. chrysosporum. In C. subvermispora however, the first exon was relatively large in comparison with the other two homologues. This structural variation did not affect the size of the gene in the abovementioned species. Model 80088 lacks ...
STRUCTURE & FUNCTION OF MYOGLOBIN
... heme as a tightly bound prosthetic group. Role of heme is different in different tissues, e.g.heme group in cytochromeselectron transport carrier. catalase part of the active site. hemoglobin and myoglobin- bind oxygen. ...
... heme as a tightly bound prosthetic group. Role of heme is different in different tissues, e.g.heme group in cytochromeselectron transport carrier. catalase part of the active site. hemoglobin and myoglobin- bind oxygen. ...
Poster - Physiology and Endocrinology: Male reproduction, deers
... major protein categories belong to carbohydrate metabolism and protein folding were highly enriched in the Biological process category, implying the important roles of the 2 processes in spermatogenesis. Further analysis of Biological process category revealed 43 proteins associated with reproductiv ...
... major protein categories belong to carbohydrate metabolism and protein folding were highly enriched in the Biological process category, implying the important roles of the 2 processes in spermatogenesis. Further analysis of Biological process category revealed 43 proteins associated with reproductiv ...
The Right Whey Protein
... The best whey proteins are derived from ultra-high quality whey protein concentrate (WPC), which is created after whole whey has been dried and filtered to remove most of its lactose, minerals and fat. The next step involves the technology of enzyme hydrolysis and several extraction and special filt ...
... The best whey proteins are derived from ultra-high quality whey protein concentrate (WPC), which is created after whole whey has been dried and filtered to remove most of its lactose, minerals and fat. The next step involves the technology of enzyme hydrolysis and several extraction and special filt ...
JCB Raver1, a dual compartment protein, is a ligand for
... since no binding was observed for a vt fragment comprising helices I–III. Remarkably, the interaction with mvt was much stronger than with vt as seen by a 10-fold increase in -galactosidase activity (Fig. 3, C compared with D), although the expression levels of both proteins in the yeast cells were ...
... since no binding was observed for a vt fragment comprising helices I–III. Remarkably, the interaction with mvt was much stronger than with vt as seen by a 10-fold increase in -galactosidase activity (Fig. 3, C compared with D), although the expression levels of both proteins in the yeast cells were ...
Informatics Software Development and Computational Biology
... What is Proteomics? • Proteomics refers to the study of the protein constituents and protein activities of a cell, a tissue or an organism. • Proteomics may be seen from several viewpoints: – Protein Expression – Protein Interaction (Interactome) ...
... What is Proteomics? • Proteomics refers to the study of the protein constituents and protein activities of a cell, a tissue or an organism. • Proteomics may be seen from several viewpoints: – Protein Expression – Protein Interaction (Interactome) ...
Virus-Host Interactions during Movement Processes
... through the vascular system. Plant viruses encode one or more nonstructural proteins specifically required for movement within their hosts and many also require their capsid (coat) protein(s). Classically, a viral movement protein (MP) is defined by its ability to increase the plasmodesmal size excl ...
... through the vascular system. Plant viruses encode one or more nonstructural proteins specifically required for movement within their hosts and many also require their capsid (coat) protein(s). Classically, a viral movement protein (MP) is defined by its ability to increase the plasmodesmal size excl ...
Studies of focal adhesion assembly
... limited repertoire of folded domains of similar structure [4]; (ii) the domains are often connected by intrinsically unfolded linker regions that provide binding sites for other proteins; and (iii) protein–protein interactions can be modulated by phosphorylation and by changes in site exposure cause ...
... limited repertoire of folded domains of similar structure [4]; (ii) the domains are often connected by intrinsically unfolded linker regions that provide binding sites for other proteins; and (iii) protein–protein interactions can be modulated by phosphorylation and by changes in site exposure cause ...
Intrinsically disordered proteins
An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules.