Molecules of Life - Morgan Community College
... The Synthesis and Breakdown of Polymers • Monomers form larger molecules by condensation reactions called dehydration reactions • Polymers are disassembled to monomers by hydrolysis, a reaction that is essentially the reverse of the dehydration reaction ...
... The Synthesis and Breakdown of Polymers • Monomers form larger molecules by condensation reactions called dehydration reactions • Polymers are disassembled to monomers by hydrolysis, a reaction that is essentially the reverse of the dehydration reaction ...
A Chemical Look at Proteins: Workhorses of the Cell
... generation of new cells) and through transcription (DNA making RNA, which is important for protein synthesis). RNA is single stranded and can fold into many different kinds of structures, and it plays several different kinds of roles in the cell. For example, messenger RNA encodes proteins, amino-ac ...
... generation of new cells) and through transcription (DNA making RNA, which is important for protein synthesis). RNA is single stranded and can fold into many different kinds of structures, and it plays several different kinds of roles in the cell. For example, messenger RNA encodes proteins, amino-ac ...
Complete amino acid sequence of bovine colostrum lowM r cysteine
... The complete amino acid sequence of bovine colostrum cysteine proteinase inhibitor was determined by sequencing native inhibitor and peptides obtained by cyanogen bromide degradation, Achromobacter lysylendopeptidase digestion and partial acid hydrolysis of reduced and S-carboxymethylated protein. A ...
... The complete amino acid sequence of bovine colostrum cysteine proteinase inhibitor was determined by sequencing native inhibitor and peptides obtained by cyanogen bromide degradation, Achromobacter lysylendopeptidase digestion and partial acid hydrolysis of reduced and S-carboxymethylated protein. A ...
Ontogenetic Changes in the Rates of Protein Synthesis and
... accounted for primarily by individual variability in the relationships of placental and fetal masses. The placental/fetal dry weight ratio ranged between 2.86 and 0.77 (Table 3) and was significantly correlated ( r = 0.84) with the R , d D R ratio (Fig. 1). There was a strong correlation ( r = 0.94) ...
... accounted for primarily by individual variability in the relationships of placental and fetal masses. The placental/fetal dry weight ratio ranged between 2.86 and 0.77 (Table 3) and was significantly correlated ( r = 0.84) with the R , d D R ratio (Fig. 1). There was a strong correlation ( r = 0.94) ...
The Ribosome, rRNA and mRNA (3.1)
... Aminoacyl transfer RNA, also called anticodon or adaptor molecule. One or more tRNAs for each amino acid. ...
... Aminoacyl transfer RNA, also called anticodon or adaptor molecule. One or more tRNAs for each amino acid. ...
Biochemistry
... – Activates specific E3 of host leading to destruction of p53 (tumor suppressor) and other DNA repair genes. ...
... – Activates specific E3 of host leading to destruction of p53 (tumor suppressor) and other DNA repair genes. ...
IndelFR: a database of indels in protein structures and their flanking
... domain has a bias for amino acid usage and secondary structure element composition (11–13). Intriguingly, the flanking regions of an indel also have some special qualities that are different from other regions. Utilizing the data stored in IndelFR database, we can display some of these qualities (Fig ...
... domain has a bias for amino acid usage and secondary structure element composition (11–13). Intriguingly, the flanking regions of an indel also have some special qualities that are different from other regions. Utilizing the data stored in IndelFR database, we can display some of these qualities (Fig ...
Amino Acids, Peptides, and Proteins
... 13. The Isoelectric Point of Histones Histones are proteins found in eukaryotic cell nuclei, tightly bound to DNA, which has many phosphate groups. The pI of histones is very high, about 10.8. What amino acid residues must be present in relatively large numbers in histones? In what way do these resi ...
... 13. The Isoelectric Point of Histones Histones are proteins found in eukaryotic cell nuclei, tightly bound to DNA, which has many phosphate groups. The pI of histones is very high, about 10.8. What amino acid residues must be present in relatively large numbers in histones? In what way do these resi ...
Journal of Agricultural and Food Chemistry
... Gorinstein et al., 1996). There also are investigations showing comparisons among soybean, oats, and amaranth in relation to nutritional, structural, and functional properties (Gorinstein, 1993; Marcone and Yada, 1992; Segura-Nieto et al., 1994). To date, there is no information on the relative stab ...
... Gorinstein et al., 1996). There also are investigations showing comparisons among soybean, oats, and amaranth in relation to nutritional, structural, and functional properties (Gorinstein, 1993; Marcone and Yada, 1992; Segura-Nieto et al., 1994). To date, there is no information on the relative stab ...
Changes in Cotton Root Proteins Correlated with Resistance to Root
... penetration. Results presented in this report show that a specific protein is produced in the resistant cotton roots at about the same time that development of the nematode is shut down. The temporal correlation of appearance of the protein and disruption of root knot nematode development opens the ...
... penetration. Results presented in this report show that a specific protein is produced in the resistant cotton roots at about the same time that development of the nematode is shut down. The temporal correlation of appearance of the protein and disruption of root knot nematode development opens the ...
- Wiley Online Library
... 70% activity of the wild-type NHase still remained in this mutant (Table 1), indicating that these His residues only partially participate in P14K function. In addition, residue Arg96, which is conserved among the self-subunit swapping chaperones (Fig. 2), was also changed to investigate any effect ...
... 70% activity of the wild-type NHase still remained in this mutant (Table 1), indicating that these His residues only partially participate in P14K function. In addition, residue Arg96, which is conserved among the self-subunit swapping chaperones (Fig. 2), was also changed to investigate any effect ...
137. - Blue Ridge Institute for Medical Research
... VEGFR2 (Flk-1/KDR, Fetal liver kinase-1/Kinase insert Domaincontaining Receptor) is the predominant mediator of VEGF-stimulated endothelial cell migration, proliferation, survival, and enhanced vascular permeability [1]. Although VEGFR2 has lower affinity for VEGF than VEGFR1, VEGFR2 exhibits robust ...
... VEGFR2 (Flk-1/KDR, Fetal liver kinase-1/Kinase insert Domaincontaining Receptor) is the predominant mediator of VEGF-stimulated endothelial cell migration, proliferation, survival, and enhanced vascular permeability [1]. Although VEGFR2 has lower affinity for VEGF than VEGFR1, VEGFR2 exhibits robust ...
Vll. Nitrogen metabolism:
... • Na+-dependent cotransport into cells • Semi-specific for categories of amino acids • Na+/K+ ATP active transport pump removes Na+ • Facilitated transporter into blood ...
... • Na+-dependent cotransport into cells • Semi-specific for categories of amino acids • Na+/K+ ATP active transport pump removes Na+ • Facilitated transporter into blood ...
Protein Folding and Expression
... proteases, which facilitates production of intact protein products. Examples of successfully expressed proteins can be seen in Table 1. This includes expression of enzymes, antigens, and cytokines. Each protein was produced at a very high level of expression and confirmed to have native biological a ...
... proteases, which facilitates production of intact protein products. Examples of successfully expressed proteins can be seen in Table 1. This includes expression of enzymes, antigens, and cytokines. Each protein was produced at a very high level of expression and confirmed to have native biological a ...
urea cycle
... • Facilitated transporter into blood • Facilitated transporters into cells of different tissues • Liver, muscle have Na+-dependent transporters into cells also ...
... • Facilitated transporter into blood • Facilitated transporters into cells of different tissues • Liver, muscle have Na+-dependent transporters into cells also ...
Poster
... During embryogenesis, in all mammals, the eyelids grow across the eye anterior, fuse together, and subsequently reopen. This process is essential for proper eye development. ADAM17 is a Zn2+ metalloprotease that has a role in cleaving numerous proteins including growth factors involved in EGFR signa ...
... During embryogenesis, in all mammals, the eyelids grow across the eye anterior, fuse together, and subsequently reopen. This process is essential for proper eye development. ADAM17 is a Zn2+ metalloprotease that has a role in cleaving numerous proteins including growth factors involved in EGFR signa ...
Hemoglobin Lecture 2
... • This allows transfer of O2 from mother to child • This explains the need for multiple Hb types • If [BPG] = 0, HbA > HbF for O2 binding • HbF has neutral Serine in place of HbA His ...
... • This allows transfer of O2 from mother to child • This explains the need for multiple Hb types • If [BPG] = 0, HbA > HbF for O2 binding • HbF has neutral Serine in place of HbA His ...
Dominant Negative Inhibition in Prion Protein
... • Reproducible differences between ∆PrPs in efficiencies of dominant-negative inhibition were observed • The differences suggests that the loop region between the second beta strand and the second alpha helix might be important for efficient inhibition • This supports the point of view that the loop ...
... • Reproducible differences between ∆PrPs in efficiencies of dominant-negative inhibition were observed • The differences suggests that the loop region between the second beta strand and the second alpha helix might be important for efficient inhibition • This supports the point of view that the loop ...
gene cloning and identification of the Circumsporozoite protein of
... precipitates a protein of approximate 50,000 Mr. To compare this in vitro product with the CS protein from sporozoites, we made a Western blot. Nonidet P-40 extracts of P. berghei sporozoites (lanes 4 and 7), translation products of total P. berghei sporozoite RNA (lanes 5 and 8), and translation pr ...
... precipitates a protein of approximate 50,000 Mr. To compare this in vitro product with the CS protein from sporozoites, we made a Western blot. Nonidet P-40 extracts of P. berghei sporozoites (lanes 4 and 7), translation products of total P. berghei sporozoite RNA (lanes 5 and 8), and translation pr ...
Urea kinetic modelling
... and which have been long postulated to be factors in uremia— Consequently using the quantitative analysis of production and removal of urea (which is urea kinetic modeling) ...
... and which have been long postulated to be factors in uremia— Consequently using the quantitative analysis of production and removal of urea (which is urea kinetic modeling) ...
Molecule of the Month: AgrA DNA Binding Domain AgrA is the
... from water (Figure 2). The helices play no role in actual binding to DNA and seem to serve only to help support the β-sheets3. An interesting feature of this molecule is that it has twofold symmetry – strands 15 and 6-10 are symmetrical, as are the 310 helices that connect them (Figure 3). The autho ...
... from water (Figure 2). The helices play no role in actual binding to DNA and seem to serve only to help support the β-sheets3. An interesting feature of this molecule is that it has twofold symmetry – strands 15 and 6-10 are symmetrical, as are the 310 helices that connect them (Figure 3). The autho ...
IDENTIFICATION OF LEAD COMPOUNDS WITH COBRA VENOM NEUTRALISING ACTIVITY IN
... showed that the hydroxyl groups (-OH) of the ligand proximadiol formed H-bonds with the hydrophobic residues HIS47, ALA22 and CYS44 of the target molecule. Cobrotoxin is the main neurotoxin found in Cobra venom, which consists of 62 amino acids stabilized by four disulphide bridges. Structural detai ...
... showed that the hydroxyl groups (-OH) of the ligand proximadiol formed H-bonds with the hydrophobic residues HIS47, ALA22 and CYS44 of the target molecule. Cobrotoxin is the main neurotoxin found in Cobra venom, which consists of 62 amino acids stabilized by four disulphide bridges. Structural detai ...
SMOOTH MUSCLE
... DIAMETER: from 10 to 100 micrometres. SHAPE: elongated & cylindrical. OUTER MEMBRANE: called sarcolemma. Nucleus & Organelles: present. Mitochondria, microsomes & ER ...
... DIAMETER: from 10 to 100 micrometres. SHAPE: elongated & cylindrical. OUTER MEMBRANE: called sarcolemma. Nucleus & Organelles: present. Mitochondria, microsomes & ER ...
Protein–protein interaction
Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.