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S2P - Zenodo
S2P - Zenodo

... International Conference on Practical Applications of Computational Biology & Bioinformatics: PACBB 2017. Porto, Portugal. 21 - June ...
lecture notes endomembrane system 4
lecture notes endomembrane system 4

... medial compartment, while addition of galactose and sialic acid occurs in the trans compartment and the TGN. 13. Because the oligosaccharide chains are added/modified on the luminal side of the ER and the GA, the distribution of carbohydrate on membrane proteins and lipids is asymmetric. That is wit ...
Carbon Compounds
Carbon Compounds

... • Stored energy (fats) • Structural- part of the cell membrane (phospholipids) • Repel water because they are nonpolar (even distribution of charge across the molecule) Ex- waxes. Helps to ‘waterproof’ a duck’s feathers • Chemical messengers (hormones such as estrogen & testosterone) Building blocks ...
Amino acids - Workforce3One
Amino acids - Workforce3One

... -central carbon atom surrounded by -amino group -carboxyl group -single hydrogen -variable R group ...
lecture 10
lecture 10

... FxFG repeats (Heat repeats 5, 6, 7 are shown in red, green and blue)  the FxFG repeats interdigitate in grooves formed by the Heat repeats  interaction of b importin with nucleoporins allows transport across the nuclear pore complex Core FxFG repeats found in nucleoporins. Each repeat is separated ...
The Structure and Function of Macromolecules
The Structure and Function of Macromolecules

... At least two carbons in the fatty acid chain are NOT “holding hands” with the maximum number of hydrogens they can  Instead two of the carbons (or more) are DOUBLY covalently bound to each other.  This results in a bending of the fatty acid tail ...
Balance Between Protein Synthesis and Degradation
Balance Between Protein Synthesis and Degradation

... negative balanced is observed when amino acids used for tissue building and energy are not replaced. In eukaryotes nitrogen balance can be affected by several catabolic conditions, such as disease, starvation, trauma, metabolic acidosis, composition of diet, and stage of growth. Regulation of Protei ...
Viral Structure Lec. 2
Viral Structure Lec. 2

... – Capsid is made up of polymeric proteins to conserve genome • Ex. 5 Kb genome requires 30,000 a/a capsid, which means 90 Kb genome just for capsid!! • Solution: use multiple copies of same protein • Viral Envelope – It is the covering of the nucleocapsid – Made up of a phospholipid bilayer – It sho ...
Answers to - Studentportalen
Answers to - Studentportalen

... (9) Growth hormone is a small alpha helical protein. Explain how this asymmetric molecule binds to and activates growth hormone receptor. (3p) (10) Epidermal growth factor, like several other growth factors, transmit signals through a receptor tyrosine kinase pathway involving the G protein Ras. Sig ...
Proteases are often associated with cancer and play a role of
Proteases are often associated with cancer and play a role of

... Proteases are often associated with cancer and play a role of leading enzymes responsible for tumour cell invasion and metastasis. Proteolytic activity enables proteases to influence tumour progression in many ways, including cleavage of extracellular matrix, which is necessary for invasion. This th ...
A.D.Hershey and Martha Chase (1952). Independent Function of
A.D.Hershey and Martha Chase (1952). Independent Function of

... 1869 - Frederick Miescher - isolates DNA or “nuclein” from cells 1879- Walter Flemming - chromosome behaviour during cell division described 1902- Waltor Sutton - observed that chromosome segregate in a pattern that match Mendels segregation pattern. 1911- Thomas Hunt Morgan - use Drosophila melanog ...
What is latency? - California State University, Fullerton
What is latency? - California State University, Fullerton

... RNA and lets polymerase elongate • Initially low level of transcription until TAT levels rise • What are possible targets? ...
Biological Molecules
Biological Molecules

... acids. The amino acids are held together by peptide bonds, so proteins are known as polypeptides.  There are usually multiple peptide chains joined together e.g. Haemoglobin has 4 polypeptide chains comprising it.  The polypeptide chains are then folded into a particular shape unique to that type ...
Molecular Ecology of Tree
Molecular Ecology of Tree

... Chemical defences often occur as pools of stored chemicals (e.g. phenolics, terpenoids, and alkaloids) to be released upon attack. However, chemical defences in trees also include enzymes such as chitinases and glucanases that can degrade components of invasive organisms, toxic proteins, and inhibit ...
Chapter 6 Section 3
Chapter 6 Section 3

... nitrogen and sometimes sulfur  Essential to all life/provides structure for tissues and organs  Amino Acids—basic building blocks of all proteins  Proteins are bonded by PEPTIDE BONDS ...
Protein synthesis and Enzyme test review
Protein synthesis and Enzyme test review

... 13. Where does transcription occur? nucleus 14. Where does translation occur? ribosome 15. How many nitrogen bases make up a codon? three 16. How many codons are in a strand of DNA that has 60 nucleotides? 20 17. How many codons would be necessary to code for a strand of protein that has 15 amino a ...
Figure 9-1
Figure 9-1

... For Pro: low a propensity caused by strain For Gly: low a propensity caused by reduced entropy and lack of hydrophobic stabilization For Ala: high a propensity caused by lack of a g substituent; reduced entropic cost; minimal hydrophobic stabilization ...
Protein quantification and detection methods
Protein quantification and detection methods

... Lifetime, nanoseconds; wavelength, nanometers ...
Protein Model Refinement
Protein Model Refinement

PowerPoint - HRSBSTAFF Home Page
PowerPoint - HRSBSTAFF Home Page

... Proteins are not made inside the nucleus, and DNA cannot exit the nucleus! So how can the instructions from the genes actually make proteins to give us our traits if they are in two places?! ...
100% ISO Protein - North Coast Naturals
100% ISO Protein - North Coast Naturals

... • No yeast, wheat or gluten • Free from Bovine Growth Hormone or BSE • Suitable for all body types and ages • Convenient to use, shakes up easily with no blending required • Available in three tasty flavours: Chocolate (made with Cocoa Camino),Vanilla, and Unflavoured (perfect for making fresh fruit ...
Contemporary Nutrition
Contemporary Nutrition

... • Foods are a means of obtaining amino acids • Cooking can make substances available – Vitamin – biotin (cooked eggs) ...
CHEM523 Final Exam
CHEM523 Final Exam

... employ? Draw the mechanism being certain to label specific amino acids, substrates, intermediates and products that occur during the reaction. ...
Structural comparison of three viral fusion proteins
Structural comparison of three viral fusion proteins

... derived membranes with the plasma-membrane, and release of mature extracellular viral particles. Homologues of the vaccinia protein have been found in capripox [2] and in orf, a parapox virus [3]. The degree of homology, when determined by amino acid identity, is low. Depending on the number of gaps ...
Tutorial_4 (2016) - Protein Alignments
Tutorial_4 (2016) - Protein Alignments

... http://www1.technion.ac.il/_local/includes/blocks/scinews-items/100513-elegans/news-item-en.htm ...
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Protein–protein interaction



Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.
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