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Multiple Choice
Multiple Choice

... 6. Though the presence of self-replicating molecules was essential for the origin of life, what could be considered as the essential requirement for the construction of a cell? A. The presence of proteins, nucleic acids and polysaccharides. B. None of the above are essential. C. Membranes D. Enzymes ...
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PPT2

... The catalysis of all biochemical reactions is done by enzymes, which contain protein. ...
Chapter 2 Water
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... very weak very short range (4 kJ/mole) molecules have to be almost touching before significant optimum when atoms are touching each other at van der Waals radius H. Weak interactions crucial to macromolecule structure All forces seen are weak compared to single bond but will use lots Just to binding ...
Proteomics methods for subcellular proteome analysis
Proteomics methods for subcellular proteome analysis

... Kit (Pierce, Rockford, IL, USA), and several others. Most of these kits can be easily used in benchtop centrifuges and are suitable for subsequent MS analysis, thereby increasing the reproducibility while being costeffective and time-effective. However, such kits are often limited with regard to wha ...
Aspekte der Thermodynamik in der Strukturbiologie Einführung in
Aspekte der Thermodynamik in der Strukturbiologie Einführung in

... • Bioinformatics = computational branch of molecular biology • in vivo – in vitro – in silico • Bioinformatics in a narrower sense: Databases and computational methods for sequences and sequence-related properties of proteins, DNA, and RNA ...
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molecular biology and phylogeny
molecular biology and phylogeny

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... – is the major protein of human plasma (3.4-4.7 g/dL) – Approximately 40% of albumin is present in plasma and the other 60% in the extracellular space – It synthesized in the liver as preproprotein – The synthesis of albumin is depressed in a variety of diseases, particularly those of the liver (dec ...
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Acuity Change in Fellow Eye

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... diseases and conditions that in majority have a genetic basis ...
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... regularity is due to hydrogen bonds formed between the atoms of the amino acid backbone of the polypeptide chain. The two most common types of secondary structure are the ones shown. (alpha helix and beta pleated sheet.) ...
Lecture 33
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... The central dogma states that once “information” has passed into protein it cannot get out again. The transfer of information from nucleic acid to nucleic acid, or from nucleic acid to protein, may be possible, but transfer from protein to protein, or from protein to nucleic acid is impossible. Info ...
Open Reading Frame (ORF) finding - Manatee
Open Reading Frame (ORF) finding - Manatee

... -The top line show the amino acid coordinates over which the match extends for our protein -The second line shows the amino acid coordinates over which the match extends for the match protein, along with the name and accession of the match protein -The last line indicates the number of amino acids i ...
Guide for Bioinformatics Project Module 1 - SGD-Wiki
Guide for Bioinformatics Project Module 1 - SGD-Wiki

... that  plays  an  important  role  for  this  organism  as  a  powerhouse  in  genetics  research.    As  with  any  sequencing  project  of   any   organism,   while   this   data   tells   us   much   about   potential   gene   locatio ...
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Protein Unit Study Guide/Review Sheets

... If you have questions, make sure to ask them. Stop in before or after school. Review questions: 1. What elements comprise proteins? C, H, O, N 2. Are proteins organic? YES – CONTAIN CARBON AND HYDROGEN, THE REQUIREMENT FOR BEING AN ORGANIC MOLECULE 3. What element MAY be present in proteins? SULFUR ...
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TRUE or FALSE - GEOCITIES.ws

... Ca++ is a second messenger for some hormones and neurotransmitters The cytosolic free Ca++ concentration is higher than the extracellular concentration Ca++ increase in a nerve terminal stimulates the release of acetylcholine The cytosolic free Ca++ concentration is lower than the extracellular conc ...
Dr Asmat Salim MM707-electrophoresis 2014
Dr Asmat Salim MM707-electrophoresis 2014

... and will move if electric field is applied.  In electrophoresis, macromolecules are characterized by their rate of movement in an electric field. This technique is used to (1) distinguish molecules on the basis of charge and shape (2) to determine molecular weight of proteins (3) to detect amino a ...
protein synthesis
protein synthesis

... A. RNA polymerase reads DNA template sense strand B. Complementary nucleotides are added to the 3' end of RNA using information in DNA as instructions **Polymerases always work from the 3' to the 5' end of the coding strand of DNA (template); thus the antiparallel structure it is forming is going fr ...
Data-driven docking for the study of biomolecular complexes
Data-driven docking for the study of biomolecular complexes

... With the presently available amount of genetic information, a lot of attention focuses on systems biology and in particular on biomolecular interactions. Considering the huge number of such interactions, and their often weak and transient nature, conventional experimental methods such as Xray crysta ...
THE EFFECT OF VARIOUS ACIDS ON THE DIGESTION OF
THE EFFECT OF VARIOUS ACIDS ON THE DIGESTION OF

... rate of liberation of carmine from carmine fibrin. As has been pointed out by various authors, there is considerable doubt as to whether any of these methods actually follows the chemical changes in the structure of the protein during hydrolysis. The recent improvements in the technique of the deter ...
Ivy Mead 24 February 2011 Bioinformatics Lab report 3 The analysis
Ivy Mead 24 February 2011 Bioinformatics Lab report 3 The analysis

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Networks and pathways

... Pathways can be broken down sub-pathways Some common pathways: signal transduction metabolic pathways, gene regulatory pathways Entities in one pathway can be found in others ...
Protein_hierarchy
Protein_hierarchy

... bonds which are formed by ........................... reactions. The linking bonds are formed between the ................ and ................. groups of the amino acids when ........................ is released from the reaction. The polypeptide chains may be folded into secondary structures, such ...
Hand Outs B 1 - University of Wisconsin–Madison
Hand Outs B 1 - University of Wisconsin–Madison

... Definitions for Parents-complex concepts in simple language for you to use with your school-aged children ...
Biomolecules - Mercer Island School District
Biomolecules - Mercer Island School District

... 5. It is used to make up cell walls in plants 6. It can store the most energy and is used for long term energy storage in animals ...
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Protein–protein interaction



Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.
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