Entropy and enthalpy of interaction between amino acid side chains
... conformation in the exit tunnel of the ribosome,2 translocation of peptides through biological channels,3 and dynamics in the crowded cellular environment.4, 5 In addition, the effects of confinement on phase transitions in watermediated interactions have significant applications in nanotribology, a ...
... conformation in the exit tunnel of the ribosome,2 translocation of peptides through biological channels,3 and dynamics in the crowded cellular environment.4, 5 In addition, the effects of confinement on phase transitions in watermediated interactions have significant applications in nanotribology, a ...
2.3 Carbon-Based Molecules
... • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. – Amino acids differ in side groups, or R groups. – Amino acids are linked by peptide bonds. ...
... • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. – Amino acids differ in side groups, or R groups. – Amino acids are linked by peptide bonds. ...
Journal of Bacteriology
... site (Fig. 2). This gene, which we designated nodO, codes for a protein of 284 amino acids with a predicted molecular size of 30,002 daltons. To test whether the gene identified above codes for the secreted protein, we have compared the predicted amino acid sequence with the sequence of the electroe ...
... site (Fig. 2). This gene, which we designated nodO, codes for a protein of 284 amino acids with a predicted molecular size of 30,002 daltons. To test whether the gene identified above codes for the secreted protein, we have compared the predicted amino acid sequence with the sequence of the electroe ...
The DsbA Signal Sequence Directs Efficient
... DsbAss was significantly more hydrophobic than the other two signal sequences (data not shown) (see Materials and Methods). Since at about this time Lee and Bernstein (17) reported that they had engineered cleavable signal sequences with higher hydrophobicity than normal and that proteins attached t ...
... DsbAss was significantly more hydrophobic than the other two signal sequences (data not shown) (see Materials and Methods). Since at about this time Lee and Bernstein (17) reported that they had engineered cleavable signal sequences with higher hydrophobicity than normal and that proteins attached t ...
GuanHongLi (275
... unique nutritional properties with being colourless, hypoallergenic, rich in essential amino acids, and has a bland taste. 5 Besides being as a staple diet for human consumption, rice is also an important starting material for starch, dextrin, grape sugar and syrup manufacturing. A mass of rice resi ...
... unique nutritional properties with being colourless, hypoallergenic, rich in essential amino acids, and has a bland taste. 5 Besides being as a staple diet for human consumption, rice is also an important starting material for starch, dextrin, grape sugar and syrup manufacturing. A mass of rice resi ...
Dear teacher/student
... peptide database). However, the following instructions assume you are using Radboud University’s BLAST tool. 3. Copy your amino acid sequence to the search field. Start the sequence query with a line >nameofyoursequence. You are now using the so called FastA-format, without which the search engine w ...
... peptide database). However, the following instructions assume you are using Radboud University’s BLAST tool. 3. Copy your amino acid sequence to the search field. Start the sequence query with a line >nameofyoursequence. You are now using the so called FastA-format, without which the search engine w ...
Transport of Storage Proteins to Protein Storage Vacuoles Is
... suggests that the vesicles with a density of 1.24 g/cm 3 mediate the transport of major storage proteins to protein storage vacuoles in maturing seeds of pumpkin and castor bean. However, the origin of these vesicles remains unknown. The ultrastructure of these vesicles, which includes an electron-d ...
... suggests that the vesicles with a density of 1.24 g/cm 3 mediate the transport of major storage proteins to protein storage vacuoles in maturing seeds of pumpkin and castor bean. However, the origin of these vesicles remains unknown. The ultrastructure of these vesicles, which includes an electron-d ...
Description of the KDD-Cup 2004 Protein Data
... Roughly, the features are divided as follow. We consider general properties such as sequence similarity, sequence-to-structure matching, secondary structure fitness, exposed surface area, and matching to the whole sequence family of the probe sequence (so called profile) to the template. Each of the ...
... Roughly, the features are divided as follow. We consider general properties such as sequence similarity, sequence-to-structure matching, secondary structure fitness, exposed surface area, and matching to the whole sequence family of the probe sequence (so called profile) to the template. Each of the ...
Use the following information and image to answer the questions
... 1. Proteins are composed of amino acid molecules linked together by peptide bonds. C, H, N, S, and O are typical atoms that compose amino acids. 2. The amino acids contain amino and carboxyl groups. Primary, secondary, tertiary, and quaternary structures of a protein molecule are necessary for the p ...
... 1. Proteins are composed of amino acid molecules linked together by peptide bonds. C, H, N, S, and O are typical atoms that compose amino acids. 2. The amino acids contain amino and carboxyl groups. Primary, secondary, tertiary, and quaternary structures of a protein molecule are necessary for the p ...
Hamster Placental Lactogen-ll Contains a Structural Feature Unique
... Cys165 and Cys 182-Cys189 (13). Presumably, analogous disulfide bonds (Cys 51-Cys 166 and Cys 183Cys191) are present in mPL-ll and rPL-ll. Purified, monomeric haPL-ll does not contain any sulfhydryl groups (10) and therefore contains three disulfide bonds in an unknown arrangement. When purified haP ...
... Cys165 and Cys 182-Cys189 (13). Presumably, analogous disulfide bonds (Cys 51-Cys 166 and Cys 183Cys191) are present in mPL-ll and rPL-ll. Purified, monomeric haPL-ll does not contain any sulfhydryl groups (10) and therefore contains three disulfide bonds in an unknown arrangement. When purified haP ...
Binding Protein HU has a Regulatory Role in the Acid Stress
... by the membrane protein AdiC to serve as substrate for the arginine decarboxylase enzyme AdiA. This leads to the formation of agmatine. Thus, the proton consumption that is involved in this reaction reduces the overall abundance of protons in the cell cytoplasm [13]. In E. coli, this system appears ...
... by the membrane protein AdiC to serve as substrate for the arginine decarboxylase enzyme AdiA. This leads to the formation of agmatine. Thus, the proton consumption that is involved in this reaction reduces the overall abundance of protons in the cell cytoplasm [13]. In E. coli, this system appears ...
Modelling neurodegeneration in Saccharomyces
... dissection in the yeast model system (see main text for details). Although there are undoubtedly conserved apoptotic mechanisms in yeast, the presence of a classical programmed cell death pathway remains controversial. Given the fundamental role of protein misfolding, quality control and degradation ...
... dissection in the yeast model system (see main text for details). Although there are undoubtedly conserved apoptotic mechanisms in yeast, the presence of a classical programmed cell death pathway remains controversial. Given the fundamental role of protein misfolding, quality control and degradation ...
4-6
... protein synthesis is depressed by ARF and protein degradation is increased even in the presence of insulin [9]. Acidosis was identified as an important factor in muscle protein breakdown. Metabolic acidosis activates the catabolism of protein and oxidation of amino acids independently of azotemia, a ...
... protein synthesis is depressed by ARF and protein degradation is increased even in the presence of insulin [9]. Acidosis was identified as an important factor in muscle protein breakdown. Metabolic acidosis activates the catabolism of protein and oxidation of amino acids independently of azotemia, a ...
Chemical synthesis of proteins
... designed to be stable to repeated cycles of Boc removal, yet to be cleanly cleaved by hydrogen fluoride. The second protocol uses the 9-fluorenylmethyloxycarbonyl (Fmoc) group for Na-amino protection. The Fmoc group is usually removed with piperidine in N,N-dimethylformamide or N-methylpyrrolidone. ...
... designed to be stable to repeated cycles of Boc removal, yet to be cleanly cleaved by hydrogen fluoride. The second protocol uses the 9-fluorenylmethyloxycarbonyl (Fmoc) group for Na-amino protection. The Fmoc group is usually removed with piperidine in N,N-dimethylformamide or N-methylpyrrolidone. ...
Isoforms of acetyl-CoA carboxylase
... important inhibitory phosphorylation site at Ser79 in rat ACC-1 is phosphorylated by AMP-activated protein kinase (AMP-PK). Additional sites at Ser-1200 and Ser-1215 may be phosphorylated by either AMP-PK or CAMP-dependent protein kinase (PKA), and although these latter two sites are phosphorylated ...
... important inhibitory phosphorylation site at Ser79 in rat ACC-1 is phosphorylated by AMP-activated protein kinase (AMP-PK). Additional sites at Ser-1200 and Ser-1215 may be phosphorylated by either AMP-PK or CAMP-dependent protein kinase (PKA), and although these latter two sites are phosphorylated ...
pdf file
... and the plasma membrane. Here, we report the identification of COD1/SPF1 (control of HMGCoA reductase degradation/SPF1) through genetic strategies intended to uncover genes involved in protein maturation and endoplasmic reticulum (ER)-associated degradation (ERAD), a quality control pathway that rid ...
... and the plasma membrane. Here, we report the identification of COD1/SPF1 (control of HMGCoA reductase degradation/SPF1) through genetic strategies intended to uncover genes involved in protein maturation and endoplasmic reticulum (ER)-associated degradation (ERAD), a quality control pathway that rid ...
Supplementary Information
... intensities were background subtracted (taking mean of channel intensities and median of background). Spots with low intensities were excluded from normalization (<150 in either or both channels).After intensity filtration only 2503 of 6155 ORFs were present in all 12 microarrays compared. An intens ...
... intensities were background subtracted (taking mean of channel intensities and median of background). Spots with low intensities were excluded from normalization (<150 in either or both channels).After intensity filtration only 2503 of 6155 ORFs were present in all 12 microarrays compared. An intens ...
Gene encoding the group B streptococcal protein R4, its
... type III and some type II and V invasive isolates conforms to these criteria. The Rib protein, although structurally and epidemiologically similar to R4, was reported as resistant to both proteases. We report here the gene encoding the R4 protein from a type III group B streptococcal isolate (76-043 ...
... type III and some type II and V invasive isolates conforms to these criteria. The Rib protein, although structurally and epidemiologically similar to R4, was reported as resistant to both proteases. We report here the gene encoding the R4 protein from a type III group B streptococcal isolate (76-043 ...
Document
... group gives a complex titration curve with two inflection points. 3. More complex amino acids with an ionizable R group show even more complex titration curves. ...
... group gives a complex titration curve with two inflection points. 3. More complex amino acids with an ionizable R group show even more complex titration curves. ...
pdf-Dokument - Universität Bonn
... GTP to GDP. GAPs include several groups based on their substrate proteins, such as ARF (ADP Ribosylation Factor) GAPs, RAB (RAS-like protein in Brain) GAPs, and RHO (RAS Homologue) GAPs. ARFGAPs act specifically inducing hydrolysis of GTP on ARFs. In Arabidopsis thaliana genome, there are 15 protein ...
... GTP to GDP. GAPs include several groups based on their substrate proteins, such as ARF (ADP Ribosylation Factor) GAPs, RAB (RAS-like protein in Brain) GAPs, and RHO (RAS Homologue) GAPs. ARFGAPs act specifically inducing hydrolysis of GTP on ARFs. In Arabidopsis thaliana genome, there are 15 protein ...
Characterisation of new intracellular membranes in Escherichia coli
... amounts of protein by generation of novel membrane structures. The cells respond to the excess membrane protein biosynthesis by a regulated increase of membrane phospholipid biosynthesis such that the lipid:protein ratio remains nearly constant at 0.4. However, the lipid:protein ratio for the prolif ...
... amounts of protein by generation of novel membrane structures. The cells respond to the excess membrane protein biosynthesis by a regulated increase of membrane phospholipid biosynthesis such that the lipid:protein ratio remains nearly constant at 0.4. However, the lipid:protein ratio for the prolif ...
Protein–protein interaction
Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.