Article 4 - Entod Pharma
... represent a better choice. The agent has several theoretical advantages over cefuroxime, including a longer half-life, concentration dependent activity, making it less dependent upon duration of activity, and a broader spectrum of cidal efficacy, he noted. It is also well tolerated in the eye. Unlik ...
... represent a better choice. The agent has several theoretical advantages over cefuroxime, including a longer half-life, concentration dependent activity, making it less dependent upon duration of activity, and a broader spectrum of cidal efficacy, he noted. It is also well tolerated in the eye. Unlik ...
Comparison of Ultrasound Biomicroscopic Parameters After Laser
... resulting from Irvine-Gass syndrome, and prior vitrectomy. This study suggests that prior history of uveitis may be an additional risk factor for developing sterile endophthalmitis after IVTA injection. Four (67 %) of six patients with sterile endophthalmitis had history of uveitis, whereas only 20 ...
... resulting from Irvine-Gass syndrome, and prior vitrectomy. This study suggests that prior history of uveitis may be an additional risk factor for developing sterile endophthalmitis after IVTA injection. Four (67 %) of six patients with sterile endophthalmitis had history of uveitis, whereas only 20 ...
Luvox and Luvox CR (fluvoxamine)
... in excessive levels of that neurotransmitter when combined with Luvox and produce a toxic syndrome known as serotonin syndrome. The early signs of serotonin syndrome are restlessness, confusion, tremors, flushing, and involuntary muscle jerks. If the medications are not stopped, the individual may d ...
... in excessive levels of that neurotransmitter when combined with Luvox and produce a toxic syndrome known as serotonin syndrome. The early signs of serotonin syndrome are restlessness, confusion, tremors, flushing, and involuntary muscle jerks. If the medications are not stopped, the individual may d ...
Skin and Soft-Tissue Infections: A Critical Review
... to infections in patients with exposure to healthcare environments, but is now identified commonly in patients without this risk factor [47]. Such infections have been identified as community-acquired MRSA (CA-MRSA), now a major causative pathogen associated with cSSSI in the United States [40, 43, 45 ...
... to infections in patients with exposure to healthcare environments, but is now identified commonly in patients without this risk factor [47]. Such infections have been identified as community-acquired MRSA (CA-MRSA), now a major causative pathogen associated with cSSSI in the United States [40, 43, 45 ...
antihypertensive drugs
... - fluid retention (usually combo-therapy with diuretic) - hypertrichosis (OTC, topical application as Rogaine) iii. Sodium Nitroprusside - used for acute emergency hypertension and congestive heart failure - used i.v., (cyanide toxicity via oral administration) - activation of guanylyl cyclase (dire ...
... - fluid retention (usually combo-therapy with diuretic) - hypertrichosis (OTC, topical application as Rogaine) iii. Sodium Nitroprusside - used for acute emergency hypertension and congestive heart failure - used i.v., (cyanide toxicity via oral administration) - activation of guanylyl cyclase (dire ...
Suggestion from clinicians
... daily and rivaroxaban vs warfarin. The finding for dabigatran was confirmed by a large Food and Drug Administration cohort study.23 Patients taking dabigatran also had significantly more dyspepsia and earlier discontinuation of study Meta-analysis of NOACs (2014) Our results show that stroke and sys ...
... daily and rivaroxaban vs warfarin. The finding for dabigatran was confirmed by a large Food and Drug Administration cohort study.23 Patients taking dabigatran also had significantly more dyspepsia and earlier discontinuation of study Meta-analysis of NOACs (2014) Our results show that stroke and sys ...
CAFERGOT
... Drugs (e.g. nevirapine, rifampicin) inducing CYP3A4 can lead to decrease in pharmacological action of ergotamine. ...
... Drugs (e.g. nevirapine, rifampicin) inducing CYP3A4 can lead to decrease in pharmacological action of ergotamine. ...
RE-MODEL
... diminished clinical effect; avoid within 24 hours after surgery Amiodarone Adjust dosing to 150 mg daily dabigatran with amiodarone Pantoprazole Co-administration with Dabigatran may diminish clinical effect ...
... diminished clinical effect; avoid within 24 hours after surgery Amiodarone Adjust dosing to 150 mg daily dabigatran with amiodarone Pantoprazole Co-administration with Dabigatran may diminish clinical effect ...
Low Molecular Weight Heparin and Warfarin or Rivaroxaban for the
... there is concern over bleeding then re-introduction should be delayed, bridging therapy with LMWH may be required if there is a more than 24 hour delay. Management of bleeding on rivaroxaban Where there is minor bleeding then the next dose of rivaroxaban should be withheld and local measures taken t ...
... there is concern over bleeding then re-introduction should be delayed, bridging therapy with LMWH may be required if there is a more than 24 hour delay. Management of bleeding on rivaroxaban Where there is minor bleeding then the next dose of rivaroxaban should be withheld and local measures taken t ...
Drug Utilization Review Board - The Oklahoma Health Care Authority
... and tonight I just want to make some brief comments on the challenges in treating Type II diabetes. In selecting appropriate drugs for Type II the clinicians are always having to balance the efficacy and risk, especially hypoglycemia and weight gain and patients who often present with comorbidities ...
... and tonight I just want to make some brief comments on the challenges in treating Type II diabetes. In selecting appropriate drugs for Type II the clinicians are always having to balance the efficacy and risk, especially hypoglycemia and weight gain and patients who often present with comorbidities ...
TB Management Guidelines
... adult dose is 15 mg/kg per day (maximum of 1000 mg) and 10 mg/kg in persons >59 years of age (maximum of 750 mg) given IM or IV. The usual dose is 750-1000 mg as a single dose 3-7 days per week. After the first 2-4 months of therapy the frequency should be reduced to two to three times weekly. Exerc ...
... adult dose is 15 mg/kg per day (maximum of 1000 mg) and 10 mg/kg in persons >59 years of age (maximum of 750 mg) given IM or IV. The usual dose is 750-1000 mg as a single dose 3-7 days per week. After the first 2-4 months of therapy the frequency should be reduced to two to three times weekly. Exerc ...
Ambien-Sonata - SWLA Center for Health Services
... Use of Alcohol and Other Medications Zaleplon and zolpidem are central nervous system (CNS) depressants that should not be taken with alcohol or other CNS depressants (e.g., barbiturates, benzodiazepines, narcotic medications). They should only be taken shortly before going to bed when needed for sl ...
... Use of Alcohol and Other Medications Zaleplon and zolpidem are central nervous system (CNS) depressants that should not be taken with alcohol or other CNS depressants (e.g., barbiturates, benzodiazepines, narcotic medications). They should only be taken shortly before going to bed when needed for sl ...
SPC - HPRA website
... 4 weeks. In certain cases extension beyond the maximum treatment period may be necessary; if so, it should not take place without re-evaluation of the patient’s status. Long-term continuous use is not recommended. Treatment should be started with the lowest recommended dose. The maximum dose should ...
... 4 weeks. In certain cases extension beyond the maximum treatment period may be necessary; if so, it should not take place without re-evaluation of the patient’s status. Long-term continuous use is not recommended. Treatment should be started with the lowest recommended dose. The maximum dose should ...
Central Nervous System Toxicity of Chemotherapy
... However, these and other “indirect” CNS complications of chemotherapy will not be addressed here. Neurotoxic complications of chemotherapy frequently present with characteristic symptoms and need to be separated from other morphologic (ie metastatic), infectious, or metabolic causes of CNS dysfuncti ...
... However, these and other “indirect” CNS complications of chemotherapy will not be addressed here. Neurotoxic complications of chemotherapy frequently present with characteristic symptoms and need to be separated from other morphologic (ie metastatic), infectious, or metabolic causes of CNS dysfuncti ...
Product Monograph Template - Standard
... the concomitant use of other CNS depressant drugs with opioid analgesics (see DRUG INTERACTIONS). If the decision is made to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. In ...
... the concomitant use of other CNS depressant drugs with opioid analgesics (see DRUG INTERACTIONS). If the decision is made to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. In ...
References
... We thank T. Weiss and colleagues who wrote an interesting correspondence citing our research letter published in a previous issue of the European Respiratory Journal [1]. We compared the findings of an individual data meta-analytic observational cohort of extensively drug-resistant (XDR) tuberculosi ...
... We thank T. Weiss and colleagues who wrote an interesting correspondence citing our research letter published in a previous issue of the European Respiratory Journal [1]. We compared the findings of an individual data meta-analytic observational cohort of extensively drug-resistant (XDR) tuberculosi ...
POST OPERATIVE ENDOPHTHALMITIS
... • Povidone-iodine (5%) has broad antibacterial, as well as antifungal & antiviral activity • It decreases conjunctival flora growth to ...
... • Povidone-iodine (5%) has broad antibacterial, as well as antifungal & antiviral activity • It decreases conjunctival flora growth to ...
RECENT MAJOR CHANGES
... Administer CANCIDAS by slow intravenous (IV) infusion over approximately 1 hour. Do not administer CANCIDAS by IV bolus administration. 2.2 Recommended Dosage in Adult Patients [18 years of age and older] The dosage and duration of CANCIDAS treatment for each indication are as follows: Empirical The ...
... Administer CANCIDAS by slow intravenous (IV) infusion over approximately 1 hour. Do not administer CANCIDAS by IV bolus administration. 2.2 Recommended Dosage in Adult Patients [18 years of age and older] The dosage and duration of CANCIDAS treatment for each indication are as follows: Empirical The ...
Page 1 of 39 KEPPRA (levetiracetam) Rx only 250 mg, 500 mg, 750
... Pharmacokinetics of levetiracetam were evaluated in 16 elderly subjects (age 61-88 years) with creatinine clearance ranging from 30 to 74 mL/min. Following oral administration of twice-daily dosing for 10 days, total body clearance decreased by 38% and the half-life was 2.5 hours longer in the elder ...
... Pharmacokinetics of levetiracetam were evaluated in 16 elderly subjects (age 61-88 years) with creatinine clearance ranging from 30 to 74 mL/min. Following oral administration of twice-daily dosing for 10 days, total body clearance decreased by 38% and the half-life was 2.5 hours longer in the elder ...
analgesic
... were randomized to 400 mg of celecoxib, followed by 200 mg every 12 hours for 10 days, or to placebo. Patients with a solitary kidney, renal insufficiency (CR > 1.8), urinary tract infection, or significant cardiovascular disease were excluded. RESULTS: A total of 57 patients provided consent of whi ...
... were randomized to 400 mg of celecoxib, followed by 200 mg every 12 hours for 10 days, or to placebo. Patients with a solitary kidney, renal insufficiency (CR > 1.8), urinary tract infection, or significant cardiovascular disease were excluded. RESULTS: A total of 57 patients provided consent of whi ...
Use of Bisphosphonates in Chronic Kidney Disease
... play a role because of its probable cumulative effect [25]. According to FDA zoledronic asid is not recommended for use in patients with severe renal impairment (CrCl ≤ 40 mL/min) [11, 26]. Physicians should monitor serum creatinine in patients with pre-existing renal compromise or other risk factor ...
... play a role because of its probable cumulative effect [25]. According to FDA zoledronic asid is not recommended for use in patients with severe renal impairment (CrCl ≤ 40 mL/min) [11, 26]. Physicians should monitor serum creatinine in patients with pre-existing renal compromise or other risk factor ...
Document
... 200mg per day. The need for the further increases should be closely monitored at weekly intervals with the dosage increased in 100mg increments to a maximum of 400mg per day in 2 or 3 divided doses. The dose of 400mg per should not be exceeded. ...
... 200mg per day. The need for the further increases should be closely monitored at weekly intervals with the dosage increased in 100mg increments to a maximum of 400mg per day in 2 or 3 divided doses. The dose of 400mg per should not be exceeded. ...
ASPIRIN
... aggregometry and tests measuring the effect on COX-1 by measuring thromboxane metabolites Increasing aspirin dose may overcome resistance, but patients may develop aspirin resistance over time on a stable dose At this point, there are no guidelines to suggest when to screen for aspirin resistanc ...
... aggregometry and tests measuring the effect on COX-1 by measuring thromboxane metabolites Increasing aspirin dose may overcome resistance, but patients may develop aspirin resistance over time on a stable dose At this point, there are no guidelines to suggest when to screen for aspirin resistanc ...
Strategies for discontinuing benzodiazepines - Gobierno
... that the available efficacy data did not provide robust evidence that a lower dose was effective for most people. However, it also considered that for some individual patients a lower dose could be effective; therefore as for any other drug used to control symptoms, individual patients should take t ...
... that the available efficacy data did not provide robust evidence that a lower dose was effective for most people. However, it also considered that for some individual patients a lower dose could be effective; therefore as for any other drug used to control symptoms, individual patients should take t ...
OsmoPrep - Salix Pharmaceuticals
... in permanent impairment of renal function and several patients required long-term dialysis. The time to onset is typically within days; however, in some cases, the diagnosis of these events has been delayed up to several months after the ingestion of these products. Patients at increased risk of acu ...
... in permanent impairment of renal function and several patients required long-term dialysis. The time to onset is typically within days; however, in some cases, the diagnosis of these events has been delayed up to several months after the ingestion of these products. Patients at increased risk of acu ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.