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Drug Treatment of Oral Sub Mucous Fibrosis
Drug Treatment of Oral Sub Mucous Fibrosis

... group SDG, multivitamin, and local heat therapy) in comparison to pentoxifylline test cases (Experimental drug group EDG, 400mg 3 times daily, as coated, sustained release tablets). The authors concluded that pentoxifylline can be used as an adjunct therapy in the management of oral submucous fibros ...
octaplex - Octapharma Canada
octaplex - Octapharma Canada

... of patients in the trial (9 only). In patients with a known predisposition to allergies, prophylactic anti-allergic medications should be considered. If allergic or anaphylactic reactions occur, the injection must be stopped immediately. Mild reactions may be controlled with glucocorticoids and/or a ...
Effectiveness of oral ivermectin for eradicating infesting mites in
Effectiveness of oral ivermectin for eradicating infesting mites in

... whole body after taking a bath and then keep the drug on body for prescribed period, however, it is really a nuisance for a family to perform the same ritual simultaneously. Chances of treatment failure are therefore high, mostly because of lack of treatment compliance. Oral ivermectin has practical ...
The New Oral Anticoagulants and a New Use for Arixtra
The New Oral Anticoagulants and a New Use for Arixtra

... Everyone is developing an antidote Oral anticoagulant inhibits factor Xa Inhibitor ...
Importance of Relative Dose Intensity in Chemotherapy
Importance of Relative Dose Intensity in Chemotherapy

... This trial compares the efficacy of R-CHOP-14 with RCHOP-21 in elderly DLBCL patients. In the preliminary analysis of 202 patients, the two-year progression-free survival rates were 49% for the R-CHOP-14 group and 63% for the R-CHOP-21 group, thus showing no statistically significant difference at t ...
LIVOSTIN Eye Drops and Nasal Spray - E
LIVOSTIN Eye Drops and Nasal Spray - E

... the levocabastine plasma concentrations achieved are very low. Steady-state concentrations of levocabastine are attained within 7 to 10 days following multiple dosage and are predictable from single-dose pharmacokinetics. Levocabastine undergoes minimal hepatic metabolism, i.e. ester glucuronidation ...
ZYRTEC LEVOCABASTINE Eye Drops and Nasal Spray
ZYRTEC LEVOCABASTINE Eye Drops and Nasal Spray

... the levocabastine plasma concentrations achieved are very low. Steady-state concentrations of levocabastine are attained within 7 to 10 days following multiple dosage and are predictable from single-dose pharmacokinetics. Levocabastine undergoes minimal hepatic metabolism, i.e. ester glucuronidation ...
COX-2
COX-2

... • ANALGESIA • ANTI-INFLAMMATORY • ANTI-PYRETIC ...
Coagulation assessment with the new generation of oral
Coagulation assessment with the new generation of oral

... was implicated in 10.5% of adult hospital admissions for adverse drug reactions over a 6-month period ending in April 2002.10 Following a survey (2004–2005) of nationally representative public health surveillance data in the USA, which disclosed that warfarin was implicated in 17.3% of ED visits for ...
Guidelines for the Use of Immunosuppressive
Guidelines for the Use of Immunosuppressive

... methyl prednisolone has been reported to induce arrhythmia, cardiovascular collapse, myocardial infarction, and severe infection. It seems prudent to administer the glucocorticoid over a period of 30 minutes or longer. Finally, studies of patients with rheumatoid arthritis have suggested that long-t ...
1.-Cardiology - PGXL Laboratories
1.-Cardiology - PGXL Laboratories

... Estimated warfarin maintenance dose requirement: 3.9 mg/day‡ _ CYP2C9 Poor Metabolizer (PM): This patient’s genotype is consistent with significantly reduced CYP2C9 enzymatic activity. Reduced CYP2C9 activity leads to lower dose requirement (e.g., warfarin) due to decreased clearance, increased elim ...
DUROGESIC Transdermal System
DUROGESIC Transdermal System

... adverse reactions occur rise with increasing patient tolerance to fentanyl. The rate of development of tolerance varies widely among individuals. At equivalent analgesic serum concentrations, fentanyl and morphine produce a similar degree of hypoventilation. A small number of patients have experienc ...
Angiotensin Converting Enzyme Inhibitors
Angiotensin Converting Enzyme Inhibitors

... some of the differences in pharmacological properties between the two drugs. The most common adverse effect with any chemical is the possibility of an allergic reaction, with a maculopapular pruritic rash, that may be accompanied by eosinophilia. Both captopril and enalapril have been described to c ...
AuspAR: Cabazitaxel - Therapeutic Goods Administration
AuspAR: Cabazitaxel - Therapeutic Goods Administration

... extraction of DEHP. Polyurethane infusion sets gave significant assay declines (presumably due to drug adsorption). Crystallisation was seen under some storage conditions outside the recommended label conditions. The PI recommends against PVC infusion containers (bags or bottles) and polyurethane in ...
Copegus - Genentech
Copegus - Genentech

... Safety and efficacy data are not available for treatment longer than 48 weeks. The safety and efficacy of COPEGUS and PEGASYS therapy have not been established in liver or other organ transplant recipients, patients with decompensated liver disease, or previous non-responders to interferon therapy. ...
Ozurdex® dexamethasone ocular implant for uveitis
Ozurdex® dexamethasone ocular implant for uveitis

... available clinical evidence does not permit an estimate of the permanence or duration of treatment (i.e. the number of implants required before treatment is discontinued for any reason). It is possible that some patients may require a number of repeated implants, whereas others will require fewer or ...
4.3. Contraindications
4.3. Contraindications

... Patients with a history of suicide related events, or those exhibiting a significant degree of suicidal ideation prior to commencement of treatment are known to be at greater risk of suicidal thoughts or suicide attempts, and should receive careful monitoring during treatment. A meta analysis of pla ...
PALS drugs
PALS drugs

... torsades de pointes ...
Denosumab: A New Therapy for Osteoporosis
Denosumab: A New Therapy for Osteoporosis

... concentrations are reached 30 minutes after administration. The half-life of subcutaneous teriparatide is 1 hour. Levels decrease to non-detectable within 3 hours. Accumulation in the bone has not been shown. Metabolism is unknown for teriparatide, however, endogenous PTH is metabolized by the liver ...
Alendrostad Veckotablett 70 mg tablet ENG SmPC
Alendrostad Veckotablett 70 mg tablet ENG SmPC

... complications. A causal relationship cannot be excluded (see section 4.8). Osteonecrosis of the jaw, generally associated with tooth extraction and/or local infection (including osteomyelitis) has been reported in patients with cancer receiving treatment regimens including primarily intravenously ad ...
new oral anticoagulant drugs (noac) and their
new oral anticoagulant drugs (noac) and their

... The Greater Manchester and Cheshire Cardiac and Stroke Network (GMCCSN) have produced guidance to ensure there is a  planned introduction for these drugs.  Guidance documents have been developed and full documents are available on the  GMCCSN website.  This guidance has warfarin as first line treatm ...
Alendronat 1A Farma 70 mg film
Alendronat 1A Farma 70 mg film

... any patient presenting with such symptoms should be evaluated for an incomplete femur fracture. Skin reactions In post-marketing experience, there have been rare reports of severe skin reactions including Stevens Johnson syndrome and toxic epidermal necrolysis. Missed dose If patients forget to take ...
Diovan - Novartis Pharmaceuticals Corporation
Diovan - Novartis Pharmaceuticals Corporation

... renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detecte ...
the file - General Practice
the file - General Practice

... Suboxone differs from buprenorphine (Buprenorphine) in that it allows for an initial dose on day one of 2-4 mgs, which may be followed by a further dose on the same day of 2-4 mg depending on the patient’s requirements. The dose thereafter can be titrated upwards by 2-8 mg per day to a maximum daily ...
AGGRENOX Prescribing Information
AGGRENOX Prescribing Information

... contained in the maximum recommended daily human dose of AGGRENOX. Reproduction studies with dipyridamole have been performed in mice, rabbits and rats at oral doses of up to 125 mg/kg, 40 mg/kg and 1000 mg/kg, respectively (about 1½, 2 and 25 times the maximum recommended daily human oral dose, res ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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