Eph signalling and morphogenesis - Development
... 1997), were identified in 1994 (Bartley et al., 1994). Ephrins exist in two classes: GPI-linked (class A) or transmembrane (class B) proteins. The receptors are now termed EphA or EphB based on sequence homologies and depending on the class of ligands (ephrins) that they bind (Eph Nomenclature Commi ...
... 1997), were identified in 1994 (Bartley et al., 1994). Ephrins exist in two classes: GPI-linked (class A) or transmembrane (class B) proteins. The receptors are now termed EphA or EphB based on sequence homologies and depending on the class of ligands (ephrins) that they bind (Eph Nomenclature Commi ...
Receptor Activation and Homer Differentially Control the Lateral
... 20 mM H EPES, pH 7.2, 10% fetal calf serum, and 2 mM penicillin, streptomycin, and glutamax at 37°C and 5% C O2. Hippocampal neurons were obtained from embryonic day 18 rat embryos, and cultured as described (Hemar et al., 1997). All cells were grown on glass coverslips. All reagents were from Invit ...
... 20 mM H EPES, pH 7.2, 10% fetal calf serum, and 2 mM penicillin, streptomycin, and glutamax at 37°C and 5% C O2. Hippocampal neurons were obtained from embryonic day 18 rat embryos, and cultured as described (Hemar et al., 1997). All cells were grown on glass coverslips. All reagents were from Invit ...
Neurogenic Inflammation in Acute Pancreatitis
... tract [27, 28, 29]. SP controls intestinal motility, blood flow, and ion and fluid transport. It inhibits secretion from the intact pancreas in dogs and rats. It also inhibits basal fluid secretion from isolated rat pancreatic ducts in a dose dependent manner. SP and its receptor neurokinin-1 (NK-1R ...
... tract [27, 28, 29]. SP controls intestinal motility, blood flow, and ion and fluid transport. It inhibits secretion from the intact pancreas in dogs and rats. It also inhibits basal fluid secretion from isolated rat pancreatic ducts in a dose dependent manner. SP and its receptor neurokinin-1 (NK-1R ...
Protective effects of sphingosine-1
... Methods and results Isolated rat cardiomyocytes were stimulated with exogenous S1P, the selective S1P1 receptor agonist SEW2871, or the S1P1/3 receptor agonist FTY720. Western blot analysis was performed to analyse downstream signalling pathways. Ischaemia–reperfusion studies were conducted in rat c ...
... Methods and results Isolated rat cardiomyocytes were stimulated with exogenous S1P, the selective S1P1 receptor agonist SEW2871, or the S1P1/3 receptor agonist FTY720. Western blot analysis was performed to analyse downstream signalling pathways. Ischaemia–reperfusion studies were conducted in rat c ...
Short Forms of Membrane Receptors: Generation and Role in
... and also by some other factors [47]. Participation of several types of serine/threonine kinases—calmodulindependent kinase, MAP-kinase, and some others—in phosphorylation of these proteins has been revealed at the present time. Besides universal regulatory mechanisms, there are tissue-specific facto ...
... and also by some other factors [47]. Participation of several types of serine/threonine kinases—calmodulindependent kinase, MAP-kinase, and some others—in phosphorylation of these proteins has been revealed at the present time. Besides universal regulatory mechanisms, there are tissue-specific facto ...
Identification of Amino Acid Residues within GABAA Receptor
... b3 subunit have shown that in contrast to homomeric a1, b2, or g2L subunits, this protein has the capacity to access the cell surface on homomeric expression as determined by immunofluorescence (Connolly et al., 1996b). In addition, homomeric b3 subunits produce spontaneously gated ion channels on e ...
... b3 subunit have shown that in contrast to homomeric a1, b2, or g2L subunits, this protein has the capacity to access the cell surface on homomeric expression as determined by immunofluorescence (Connolly et al., 1996b). In addition, homomeric b3 subunits produce spontaneously gated ion channels on e ...
Introduction:
... Prediction of Transmembrane helices: Prediction of transmembrane helices of the olfactory receptor O2D2 was done using TMHMM v. 2.0 (Sonnhammer, et. al., 1998). It was predicted to be a seven helix bundle similar to GPCR as shown in Fig. 1A. It is interesting to note that the putative metal binding ...
... Prediction of Transmembrane helices: Prediction of transmembrane helices of the olfactory receptor O2D2 was done using TMHMM v. 2.0 (Sonnhammer, et. al., 1998). It was predicted to be a seven helix bundle similar to GPCR as shown in Fig. 1A. It is interesting to note that the putative metal binding ...
Biology of Cancer - Tunghai University
... growth factor receptorbound protein 2 SH2, SH3: Src homolog 2 or 3 Sos: son of sevenless ...
... growth factor receptorbound protein 2 SH2, SH3: Src homolog 2 or 3 Sos: son of sevenless ...
apoptosis - Fort Bend ISD
... Apoptosis or programmed cell death, is carefully coordinated collapse of cell, protein degradation , DNA fragmentation followed by rapid engulfment of corpses by neighbouring cells. ...
... Apoptosis or programmed cell death, is carefully coordinated collapse of cell, protein degradation , DNA fragmentation followed by rapid engulfment of corpses by neighbouring cells. ...
Analysis of the Juxtamembrane Dileucine Motif in the Insulin Receptor
... insulin receptor, we mutated the LeuLeu residues to MetSer and AlaAla, and expressed the various recombinant receptors in NIH-3T3 cells. Metabolic labeling studies confirmed that the mutant receptors were synthesized, processed, and transported to the plasma membrane normally (data not shown) (19). ...
... insulin receptor, we mutated the LeuLeu residues to MetSer and AlaAla, and expressed the various recombinant receptors in NIH-3T3 cells. Metabolic labeling studies confirmed that the mutant receptors were synthesized, processed, and transported to the plasma membrane normally (data not shown) (19). ...
Chapter 15
... • Cells express receptors for extracellular matrix proteins. • The proteins in the extracellular matrix and cell junctions control: – the three-dimensional organization of cells in tissues – the growth, movement, shape, and differentiation of these cells ...
... • Cells express receptors for extracellular matrix proteins. • The proteins in the extracellular matrix and cell junctions control: – the three-dimensional organization of cells in tissues – the growth, movement, shape, and differentiation of these cells ...
Chapter 45 - Groupfusion.net
... cascade that leads to the conversation of glycogen to glucose • Intracellular receptors are bound by hormones that are lipidsoluble. The receptor then acts as a transcription factor, causing a change in gene expresion. • Example: Testerone and estrogen enter the nuclei of target cells, bind the DNA, ...
... cascade that leads to the conversation of glycogen to glucose • Intracellular receptors are bound by hormones that are lipidsoluble. The receptor then acts as a transcription factor, causing a change in gene expresion. • Example: Testerone and estrogen enter the nuclei of target cells, bind the DNA, ...
Immunocytochemical Localization of the
... Department of Anatomy, McGill L'niversity, 3640 L'nirersily Street, Montreal, Quebec, Canada H3A 2B2 [T. A..D. OJ; and Department of Human Biological Chemistryana Genetics, t 'niversity of Texas Medical Rranch. Galveston, Texas [E. B. T.J ...
... Department of Anatomy, McGill L'niversity, 3640 L'nirersily Street, Montreal, Quebec, Canada H3A 2B2 [T. A..D. OJ; and Department of Human Biological Chemistryana Genetics, t 'niversity of Texas Medical Rranch. Galveston, Texas [E. B. T.J ...
Topic 21 - FSU Biology
... ovary and testes 3. thyroid stimulating hormone (TSH) - stimulates thyroid to release thyroid hormone 4. adrenocorticotropic hormone- causes the cortical region of the adrenal gland to release the hormone cortisol (important in carbohydrate and protein metabolism) An example of control of hormone se ...
... ovary and testes 3. thyroid stimulating hormone (TSH) - stimulates thyroid to release thyroid hormone 4. adrenocorticotropic hormone- causes the cortical region of the adrenal gland to release the hormone cortisol (important in carbohydrate and protein metabolism) An example of control of hormone se ...
Chapter 11 - My Teacher Site
... • The G protein is loosely attached to cytoplasmic side of membrane • It functions as a molecular switch that is either “on” or “off” • Inactive form: GDP (guanosine diphosphate) is bound to G protein • Active form: GTP (guanosine triphosphate) is bound to G protein • The receptor and G protein work ...
... • The G protein is loosely attached to cytoplasmic side of membrane • It functions as a molecular switch that is either “on” or “off” • Inactive form: GDP (guanosine diphosphate) is bound to G protein • Active form: GTP (guanosine triphosphate) is bound to G protein • The receptor and G protein work ...
Chapter 45 Hormones and the Endocrine System
... Depending on the species, the pineal body has connections from the eyes, and receives input about the intensity of light and length of the day Melatonin secretion is a link between a biological clock daily or seasonal activity. In some animals, mating behavior and gonadal size varies with the length ...
... Depending on the species, the pineal body has connections from the eyes, and receives input about the intensity of light and length of the day Melatonin secretion is a link between a biological clock daily or seasonal activity. In some animals, mating behavior and gonadal size varies with the length ...
Molecular Physiology: Enzymes and Cell Signaling Proteins Binding
... Signaling Cascade Function 4. distribute signal so that several different processes can be altered 5. modulate signal – each step of the cascade can be influenced by other factors – signal can be altered depending on prevalent conditions ...
... Signaling Cascade Function 4. distribute signal so that several different processes can be altered 5. modulate signal – each step of the cascade can be influenced by other factors – signal can be altered depending on prevalent conditions ...
Distribution of P2X receptors in the rat adrenal gland
... The specificity of the P2X antibodies has been verified by immunoblotting with membrane preparations from cloned P2X1–7 receptor-expressing CHO-K1 cells or 1321N1 cells (Oglesby et al. 1999). The antibodies recognize only one protein of the expected size in the heterologous expression systems and ha ...
... The specificity of the P2X antibodies has been verified by immunoblotting with membrane preparations from cloned P2X1–7 receptor-expressing CHO-K1 cells or 1321N1 cells (Oglesby et al. 1999). The antibodies recognize only one protein of the expected size in the heterologous expression systems and ha ...