ADRENERGIC SYSTEM - LEC.2 2008
... 4- promote the uptake of potassium into cells lead to fall in the extra cellular potassium which may cause fall in the plasma potassium concentration ( through Beta- 2 receptors ). Effects on endocrine function and leukocytosis : 1- increase insulin secretion ( through Beta receptors ) . 2- inhibiti ...
... 4- promote the uptake of potassium into cells lead to fall in the extra cellular potassium which may cause fall in the plasma potassium concentration ( through Beta- 2 receptors ). Effects on endocrine function and leukocytosis : 1- increase insulin secretion ( through Beta receptors ) . 2- inhibiti ...
After myocardial infarction carvedilol improves insulin resistance
... Due to the advancement in the drug science and developments in medicinal treatment; mortality has declined even in developing countries. Many potentially fatal diseases can be completely cured by modern treatments; however, the number of patients suffering from particular chronic diseases like diabe ...
... Due to the advancement in the drug science and developments in medicinal treatment; mortality has declined even in developing countries. Many potentially fatal diseases can be completely cured by modern treatments; however, the number of patients suffering from particular chronic diseases like diabe ...
Ivabradine and the SIGNIFY conundrum
... Ivabradine is a novel antianginal agent that inhibits the sinus node If channel to produce a dose-dependent bradycardia and thus antiischaemic effects without significant direct effects on vasomotor tone, blood pressure, or myocardial contractility. Previous studies have shown it to be superior to p ...
... Ivabradine is a novel antianginal agent that inhibits the sinus node If channel to produce a dose-dependent bradycardia and thus antiischaemic effects without significant direct effects on vasomotor tone, blood pressure, or myocardial contractility. Previous studies have shown it to be superior to p ...
JNC 7 Organizational Structure - Karachi Institute of Heart Diseases
... regularly. In contrast, HRT does not raise BP. Development of HTN—consider other forms of contraception. ...
... regularly. In contrast, HRT does not raise BP. Development of HTN—consider other forms of contraception. ...
Hypertension
... The older the patient, the less aggressive BP control Controlling diastolic to < 90 in ages 30-59 is very important BP goal may be > 140/90 in CKD patients without albuminuria if > 70 years old BP goal in patients with urine albumin > 30-mg/g creatinine who are 60 and older is the same as un ...
... The older the patient, the less aggressive BP control Controlling diastolic to < 90 in ages 30-59 is very important BP goal may be > 140/90 in CKD patients without albuminuria if > 70 years old BP goal in patients with urine albumin > 30-mg/g creatinine who are 60 and older is the same as un ...
Cholinergic and Anticholinergic Drugs 1
... -Sjogren syndrome (immunologic disorder with destruction of the exocrine glands) leading to mucosal dryness ...
... -Sjogren syndrome (immunologic disorder with destruction of the exocrine glands) leading to mucosal dryness ...
Beta-Blockers and Beta- Agonists: What Is the
... asthma or COPD. A decreased response to beta-agonists seems to be the most commonly observed effect of non-cardioselective beta-blockers in these patients, although increased airway hyperresponsiveness was observed with both types of beta-blockers. Cardioselective beta-blockers, administered at dose ...
... asthma or COPD. A decreased response to beta-agonists seems to be the most commonly observed effect of non-cardioselective beta-blockers in these patients, although increased airway hyperresponsiveness was observed with both types of beta-blockers. Cardioselective beta-blockers, administered at dose ...
Review: Combination treatment for hypertension
... more than 20 mmHg systolic and 10 mmHg diastolic above the target (goal) blood pressure, when there is subclinical organ damage (diabetes, renal, cardiovascular disease).2 The choice between initiating monotherapy or combination therapy is often based more on wisdom and experience than trial evidenc ...
... more than 20 mmHg systolic and 10 mmHg diastolic above the target (goal) blood pressure, when there is subclinical organ damage (diabetes, renal, cardiovascular disease).2 The choice between initiating monotherapy or combination therapy is often based more on wisdom and experience than trial evidenc ...
Inhibitors of angiotensin
... – CNS: sedation, severe mental depression, & extrapyramidal effects resembling Parkinson's disease – PNS: nasal congestion, postural hypotension, diarrhea, bradycardia, increased gastric secretion, and impotence ...
... – CNS: sedation, severe mental depression, & extrapyramidal effects resembling Parkinson's disease – PNS: nasal congestion, postural hypotension, diarrhea, bradycardia, increased gastric secretion, and impotence ...
07 Rhinitis & cough
... o Non-pharmacological therapy – Avoidance of irritants/ allergen – Dusting/vacuuming; washing of bed sheets – Intake of fluids ...
... o Non-pharmacological therapy – Avoidance of irritants/ allergen – Dusting/vacuuming; washing of bed sheets – Intake of fluids ...
Protective effects of betaglucin on myocardial tissue during
... Results: The MI mass in both rats and dogs was significantly reduced by betaglucin (30 and 100 mg/kg, P<0.01) and propranolol (P<0.01). In anesthetized dogs, coronary artery blood flow was increased significantly by betaglucin (30 and 100 mg/kg, P<0.01), but blood pressure, heart rate and ventricula ...
... Results: The MI mass in both rats and dogs was significantly reduced by betaglucin (30 and 100 mg/kg, P<0.01) and propranolol (P<0.01). In anesthetized dogs, coronary artery blood flow was increased significantly by betaglucin (30 and 100 mg/kg, P<0.01), but blood pressure, heart rate and ventricula ...
Pharmacology/Therapeutics II Block I Lectures
... a. Category A – Studies in women during the first trimester are negative. b. Category B – Either animal studies have not demonstrated a risk and studies in women are not available; or an adverse effect seen in animals was not confirmed in a human trial in the first trimester. c. Category C – Either ...
... a. Category A – Studies in women during the first trimester are negative. b. Category B – Either animal studies have not demonstrated a risk and studies in women are not available; or an adverse effect seen in animals was not confirmed in a human trial in the first trimester. c. Category C – Either ...
A Review: Stereochemical consideration and eudismic ratio in chiral
... that it led to prolong the cardiac repolariozation, and the studies were stopped. Although since last 15 years, racemic fluoxetine has been shown to be a safe and effective antidepressant, but due to safety concern, the (R)-enantiomer formulation was not viable [23]. The clinical findings highlighte ...
... that it led to prolong the cardiac repolariozation, and the studies were stopped. Although since last 15 years, racemic fluoxetine has been shown to be a safe and effective antidepressant, but due to safety concern, the (R)-enantiomer formulation was not viable [23]. The clinical findings highlighte ...
IN-SILICO PROTEIN LIGAND INTERACTION STUDY OF TYPICAL ANTIPSYCHOTIC DRUGS
... Both generations of medication tend to block receptors in the brain's dopamine pathways, but compared to the typicals, the atypicals are less likely to cause extrapyramidal motor control disabilities in patient, which include unsteady Parkinson's disease-type movements, body rigidity and involuntary ...
... Both generations of medication tend to block receptors in the brain's dopamine pathways, but compared to the typicals, the atypicals are less likely to cause extrapyramidal motor control disabilities in patient, which include unsteady Parkinson's disease-type movements, body rigidity and involuntary ...
m5zn_a6cb78119c5a815
... b- fetal risk NOT demonstrated in animal studies but there are no controlled studies in pregnant women or animal reproduction studies have shown an adverse effect that was NOT confirmed in controlled studies in women during trimester c-either animal study have revealed adverse effect on the fetus an ...
... b- fetal risk NOT demonstrated in animal studies but there are no controlled studies in pregnant women or animal reproduction studies have shown an adverse effect that was NOT confirmed in controlled studies in women during trimester c-either animal study have revealed adverse effect on the fetus an ...
anticholinergic drugs
... ciliary paralysis (have high ciliary tone). • Retinal examination - when mydriasis is required , So for complete examination, eye drops or ointment. (less systemic absorbtion of ointment form by passage through naso-lacrimal duct) • Shorter acting anti-muscarinics (Cyclopentolate and tropicamide) ha ...
... ciliary paralysis (have high ciliary tone). • Retinal examination - when mydriasis is required , So for complete examination, eye drops or ointment. (less systemic absorbtion of ointment form by passage through naso-lacrimal duct) • Shorter acting anti-muscarinics (Cyclopentolate and tropicamide) ha ...
Predicting Cardiac Risk of Anti-Cancer Drugs: A Role for Human
... Cardiotoxicity is a major complication of many anti-cancer drugs. Acute effects on cardiac ion channels alter cardiac excitability and induce arrhythmias and ultimately heart failure can develop during chronic treatment. Current in vitro strategies for detecting these risks are minimal and often ine ...
... Cardiotoxicity is a major complication of many anti-cancer drugs. Acute effects on cardiac ion channels alter cardiac excitability and induce arrhythmias and ultimately heart failure can develop during chronic treatment. Current in vitro strategies for detecting these risks are minimal and often ine ...
Patrick chapter 19 part 2
... Steroid acts as a spacer for the quaternary centres (1.09nm) Acyl groups are added to introduce the Ach skeleton Faster onset then tubocurarine but slower than suxamethonium Longer duration of action than suxamethonium (45 min) No effect on blood pressure and fewer side effects © 1 ...
... Steroid acts as a spacer for the quaternary centres (1.09nm) Acyl groups are added to introduce the Ach skeleton Faster onset then tubocurarine but slower than suxamethonium Longer duration of action than suxamethonium (45 min) No effect on blood pressure and fewer side effects © 1 ...
Adrenergic Agonists
... A portion of the released Norepinephrine “circles back” and reacts with the α2-receptors on the neuronal membrane (see Figure 6.5). The stimulation of the α2-receptors causes feedback inhibition of the ongoing release of Norepinephrine from the stimulated adrenergic neuron. This inhibitory action de ...
... A portion of the released Norepinephrine “circles back” and reacts with the α2-receptors on the neuronal membrane (see Figure 6.5). The stimulation of the α2-receptors causes feedback inhibition of the ongoing release of Norepinephrine from the stimulated adrenergic neuron. This inhibitory action de ...
Hypertensive Emergencies in Children
... Arterial and venous vasodilator No chronotropic or inotropic effects Extremely short half-life Easily titrated to effect Dose: 0.3-0.5 micrograms/kg/min. Maximum 8 mcg/kg/min Most patients will respond at rates of 3 mcg/kg/min ...
... Arterial and venous vasodilator No chronotropic or inotropic effects Extremely short half-life Easily titrated to effect Dose: 0.3-0.5 micrograms/kg/min. Maximum 8 mcg/kg/min Most patients will respond at rates of 3 mcg/kg/min ...
Beta Blockers for Migraine - Brigham and Women`s Faulkner Hospital
... case can be made against the indiscriminate use of propranolol for prophylaxis in migraine . . . the same prudence should extend to the use of propranolol as to the use of ergotamines and oral contraceptive pills in cases of complicated migraine.”22 Assumption No. 3: “Beta-blockers might cause or ex ...
... case can be made against the indiscriminate use of propranolol for prophylaxis in migraine . . . the same prudence should extend to the use of propranolol as to the use of ergotamines and oral contraceptive pills in cases of complicated migraine.”22 Assumption No. 3: “Beta-blockers might cause or ex ...
File
... Drugs interact with receptors by means of chemical forces or bonds. These are of three major types: 1. Covalent: It is very strong and in many cases not reversible under biologic conditions. Thus, the duration of drug action is frequently, but not necessarily, prolonged (irreversible) 2. Electrosta ...
... Drugs interact with receptors by means of chemical forces or bonds. These are of three major types: 1. Covalent: It is very strong and in many cases not reversible under biologic conditions. Thus, the duration of drug action is frequently, but not necessarily, prolonged (irreversible) 2. Electrosta ...
Side Effects
... Drug Interactions Steroids increase the metabolism of barbiturates, phenytoin, rifampicin, salicylates, antihypertensive, anti diabetic and increase in their dosage during concomitant therapy is therefore essential. ...
... Drug Interactions Steroids increase the metabolism of barbiturates, phenytoin, rifampicin, salicylates, antihypertensive, anti diabetic and increase in their dosage during concomitant therapy is therefore essential. ...
C
... vascular disease.[5] In addition, ALLHAT participants randomised to lisinopril experienced a higher risk of stroke, combined cardiovascular disease and angioedema than those assigned to the calcium channel antagonist amlodipine, but conversely experienced less heart failure.[5,6] In general, ACE inh ...
... vascular disease.[5] In addition, ALLHAT participants randomised to lisinopril experienced a higher risk of stroke, combined cardiovascular disease and angioedema than those assigned to the calcium channel antagonist amlodipine, but conversely experienced less heart failure.[5,6] In general, ACE inh ...